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Barbara J. McClure
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Journal Articles

Asciminib is a novel inhibitor of ABL1 and ABL2 gene fusions in ALL but requires the ABL SH3 domain for efficacy

Laura N. Eadie, Elias Lagonik, Elyse C. Page, Caitlin E. Schutz, Susan L. Heatley, Barbara J. McClure, Michelle O. Forgione, David T. Yeung, Timothy P. Hughes, Deborah L. White
Journal: Blood
Blood (2024) 144 (9): 1022–1026.
https://doi.org/10.1182/blood.2024024776
Published: 2024
Includes: Supplemental data
Journal Articles

Modeling Relapsed, Refractory Acute Lymphoblastic Leukemia from a Child with Neurofibromatosis

Susan L Heatley, Elyse C Page, Laura N Eadie, Barbara J McClure, Jacqueline Rehn, David T Yeung, Michael Philip Osborn, Tamas Revesz, Maria Kirby, Deborah L White
Journal: Blood
Blood (2021) 138 (Supplement 1): 1317.
https://doi.org/10.1182/blood-2021-150086
Published: 2021
Journal Articles

Acquired Mutations within the JAK2 Kinase Domain Confer Resistance to JAK Inhibitors in an in Vitro model of a High-Risk Acute Lymphoblastic Leukemia

Charlotte EJ Downes, BS, Barbara J McClure, BSc,PhD, Jacqueline Rehn, MSc(BioTech), James Breen, BSc,PhD, John B Bruning, BSc,PhD, David T Yeung, BSc,PhDFRACP,FRCPA,MBBS, Deborah L White, PhDFFSc(RCPA)
Journal: Blood
Blood (2020) 136 (Supplement 1): 5–6.
https://doi.org/10.1182/blood-2020-133491
Published: 2020
Journal Articles

Next Generation Genomic Analyses in T-ALL Patients Identify Recurrent and Novel Genomic Abnormalities

Laura N Eadie, BSc, PhD, Jacqueline Rehn, MSc(BioTech), Susan L Heatley, PhD MD, Barbara J McClure, BSc,PhD, Caitlin Schutz Schutz, BSc (Hons), James Breen, BSc,PhD, Timothy P. Hughes, MDMBBS,FRACP,FRCPA, David T Yeung, BSc,PhDFRACP,FRCPA,MBBS, Rosemary Sutton, BSc MSc PhD, Deborah L White, PhDFFSc(RCPA)
Journal: Blood
Blood (2020) 136 (Supplement 1): 13–14.
https://doi.org/10.1182/blood-2020-138995
Published: 2020
Journal Articles

Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML

Jason A. Powell, Daniel Thomas, Emma F. Barry, Chung H. Kok, Barbara J. McClure, Anna Tsykin, L. Bik To, Anna Brown, Ian D. Lewis, Kirsten Herbert, Gregory J. Goodall, Terence P. Speed, Norio Asou, Bindya Jacob, Motomi Osato, David N. Haylock, Susan K. Nilsson, Richard J. D'Andrea, Angel F. Lopez, Mark A. Guthridge
Journal: Blood
Blood (2009) 114 (23): 4859–4870.
https://doi.org/10.1182/blood-2009-02-204818
Published: 2009
Includes: Supplemental data
Journal Articles

Expression Profiling of a Hemopoietic Cell Survival Transcriptome Identifies a Functional Prognostic Gene Signature in Normal Karyotype AML.

Mark Guthridge, Daniel Thomas, MD, Emma F Barry, Kok H Chung, Barbara J McClure, L. Bik To, MD, Greg Goodall, Terry P Speed, Motomi Osato, David Haylock, Susie Nilsson, MD, Richard D'Andrea, PhD, Angel Lopez, Jason A Powell, PhD
Journal: Blood
Blood (2009) 114 (22): 1618.
https://doi.org/10.1182/blood.V114.22.1618.1618
Published: 2009
Journal Articles

The phosphoserine-585–dependent pathway of the GM-CSF/IL-3/IL-5 receptors mediates hematopoietic cell survival through activation of NF-κB and induction of bcl-2

Mark A. Guthridge, Emma F. Barry, Fernando A. Felquer, Barbara J. McClure, Frank C. Stomski, Hayley Ramshaw, Angel F. Lopez
Journal: Blood
Blood (2004) 103 (3): 820–827.
https://doi.org/10.1182/blood-2003-06-1999
Published: 2004
Journal Articles

Molecular assembly of the ternary granulocyte-macrophage colony-stimulating factor receptor complex

Barbara J. McClure, Timothy R. Hercus, Bronwyn A. Cambareri, Joanna M. Woodcock, Christopher J. Bagley, Geoff J. Howlett, Angel F. Lopez
Journal: Blood
Blood (2003) 101 (4): 1308–1315.
https://doi.org/10.1182/blood-2002-06-1903
Published: 2003
Journal Articles

Structure of the activation domain of the GM-CSF/IL-3/IL-5 receptor common β-chain bound to an antagonist

Jamie Rossjohn, William J. McKinstry, Joanna M. Woodcock, Barbara J. McClure, Timothy R. Hercus, Michael W. Parker, Angel F. Lopez, Christopher J. Bagley
Journal: Blood
Blood (2000) 95 (8): 2491–2498.
https://doi.org/10.1182/blood.V95.8.2491
Published: 2000
Journal Articles

The Human Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF ) Receptor Exists as a Preformed Receptor Complex That Can Be Activated by GM-CSF, Interleukin-3, or Interleukin-5

Joanna M. Woodcock, Barbara J. McClure, Frank C. Stomski, Michael J. Elliott, Christopher J. Bagley, Angel F. Lopez
Journal: Blood
Blood (1997) 90 (8): 3005–3017.
https://doi.org/10.1182/blood.V90.8.3005
Published: 1997