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Karanpreet Bhatia
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Journal Articles

Targeting TP53 promotes anti-leukemia immunity and enhances CD70 CAR-T efficacy in AML by transcriptionally upregulating CD70

Free
Chuqi Wang, Jordan Yong Ming Tan, Previtha Vale, Nishtha Chitkara, Yuhan Wang, Yuan Song, Fang Qi Lim, Yun Li, Karanpreet Bhatia, Yash Manish Agrawal, Haiyan Liu, Nicholas RJ Gascoigne, Shruti Bhatt
Journal: Blood
Blood (2025) 146 (Supplement 1): 2349.
https://doi.org/10.1182/blood-2025-2349
Published: 2025
Journal Articles

Evidence for pre-existing myeloma cells with a gene expression pattern associated with resistance to BCMA CAR T cells.

Free
Angelica Amanso, Karanpreet Bhatia, Mackenzie Mekler, James Ackley, Pankoj Das, London Harper, Holly Lee, Madhav Dhodapkar, Stanley Riddell, Paola Neri, Nizar Bahlis, Sagar Lonial, Adam Marcus, Lawrence Boise
Journal: Blood
Blood (2025) 146 (Supplement 1): 1031.
https://doi.org/10.1182/blood-2025-1031
Published: 2025
Journal Articles

Functional genomic screens identify positive and negative regulators of venetoclax resistance

Free
Beena Thomas, Karanpreet Bhatia, Devin Bog, Benjamin Barwick, Constantine Mitsiades, Lawrence Boise, Vikas Gupta
Journal: Blood
Blood (2025) 146 (Supplement 1): 5733.
https://doi.org/10.1182/blood-2025-5733
Published: 2025
Journal Articles

Dissection of non-genetic resistance mechanisms by lineage tracing and single cell multiomics reveals drug-specific persister programs in Acute Myeloid Leukemia

Free
Karanpreet Bhatia, Xiao Xian Lin, Ankit Jana, Emanuelle Grody, Ryan Jeremy Lim Jing Wei, Shawn Koh Jia Jun, Elisha Teh Jia Yu, Cin thet Kyi, Prasad Iyer, Greg Kellogg, Yogesh Goyal, Lawrence Boise, Yaara Oren, Shruti Bhatt
Journal: Blood
Blood (2025) 146 (Supplement 1): 640.
https://doi.org/10.1182/blood-2025-640
Published: 2025
Journal Articles

CD43 functions as a CD47 independent “don't eat me” signal and novel immune checkpoint in AML

Free
Yun Li, Chuqi Wang, Javier Sanmartín‑Martínez, Bob vangasteren, Jordan Yong Ming Tan, Shaista Jasdanwala, Karanpreet Bhatia, Ankit Jana, Xiao Xian Lin, Yuhan Wang, Peter Miller, Adam Sperling, Anna Marneth, Shruti Bhatt
Journal: Blood
Blood (2025) 146 (Supplement 1): 5025.
https://doi.org/10.1182/blood-2025-5025
Published: 2025
Journal Articles

Targeting Mitochondrial Apoptotic Priming State to Personalize Therapy for Relapsed Acute Myeloid Leukemia

Free
Elyse Olesinski, Karanpreet Bhatia, Chuqi Wang, Marissa Pioso, Shu Xuan Ng, Xiao Xian Lin, Vedant Sandhu, Binyam Yilma, Stephan Rainer Maximilian Bohl, Jeremy Ryan, Disha Malani, Marlise R. Luskin, Olli Kallioniemi, Kimmo Porkka, Allen Yeoh, Sophia Adamia, Wee Joo Chng, Motomi Osato, David M. Weinstock, Jacqueline S. Garcia, Anthony G. Letai, Shruti Bhatt
Journal: Blood
Blood (2023) 142 (Supplement 1): 48.
https://doi.org/10.1182/blood-2023-189156
Published: 2023