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Journal Articles

An erythroid-to-myeloid cell fate conversion is elicited by LSD1 inactivation

Lei Yu, Greggory Myers, Chia-Jui Ku, Emily Schneider, Yu Wang, Sharon A. Singh, Natee Jearawiriyapaisarn, Andrew White, Takashi Moriguchi, Rami Khoriaty, Masayuki Yamamoto, Michael G. Rosenfeld, Julien Pedron, John H. Bushweller, Kim-Chew Lim, James Douglas Engel

Blood (2021) 138 (18): 1691–1704.

https://doi.org/10.1182/blood.2021011682

Published: 2021

Includes: Supplemental data

Journal Articles

How KEAP1 Deletion in Single Cell Mitigates Sickle Cell Pathology

Nadine Keleku Lukwete, PhD, Mikiko Suzuki, PhD, Harit Panda, Akihito Otsuki, PhD, Fumiki Katsuoka, PhD, Ritsumi Saitou, MD, Daisuke Saigusa, PhD, Akira Uruno, MD PhD, Masayuki Yamamoto, MD PhD

Blood (2018) 132 (Supplement 1): 2353.

https://doi.org/10.1182/blood-2018-99-110502

Published: 2018

Journal Articles

Role of GATA2 in the Maintenance of the Bone Marrow Microenvironment

Shin Hasegawa, Tohru Fujiwara, MD PhD, Yoko Okitsu, MD PhD, Hiroki Kato, MD, PhD, Yuki Sato, Noriko Fukuhara, MD PhD, Yasushi Onishi, MD PhD, Kenichi Ishizawa, Ritsuko Shimizu, MD PhD, Masayuki Yamamoto, MD PhD, Hideo Harigae, MD

Blood (2017) 130 (Supplement 1): 3781.

https://doi.org/10.1182/blood.V130.Suppl_1.3781.3781

Published: 2017

Journal Articles

GATA2 haploinsufficiency accelerates EVI1-driven leukemogenesis

Saori Katayama, Mikiko Suzuki, Ayaka Yamaoka, Nadine Keleku-Lukwete, Fumiki Katsuoka, Akihito Otsuki, Shigeo Kure, James Douglas Engel, Masayuki Yamamoto

Blood (2017) 130 (7): 908–919.

https://doi.org/10.1182/blood-2016-12-756767

Published: 2017

Includes: Supplemental data

Journal Articles

Specific Deletion of Keap1 in Endothelial Cells or/and Macrophages of SCD Mice Induces Nrf2 to Protect Tissues Against Oxidative Insults

Nadine Keleku-Lukwete, MD PhD, Panda Harit, Eriko Naganuma, Mikiko Suzuki, PhD, Masayuki Yamamoto, MD PhD

Blood (2016) 128 (22): 2475.

https://doi.org/10.1182/blood.V128.22.2475.2475

Published: 2016

Journal Articles

GATA2 regulates dendritic cell differentiation

Koichi Onodera, Tohru Fujiwara, Yasushi Onishi, Ari Itoh-Nakadai, Yoko Okitsu, Noriko Fukuhara, Kenichi Ishizawa, Ritsuko Shimizu, Masayuki Yamamoto, Hideo Harigae

Blood (2016) 128 (4): 508–518.

https://doi.org/10.1182/blood-2016-02-698118

Published: 2016

Includes: Supplemental data

Journal Articles

GATA-2 Regulates Dendritic Cell Differentiation

Koichi Onodera, MD, PhD, Tohru Fujiwara, MD, PhD, Yasushi Onishi, MD, PhD, Ari Itoh-Nakadai, PhD, Yoko Okitsu, MD PhD, Noriko Fukuhara, MD PhD, Kenichi Ishizawa, MD, PhD, Ritsuko Shimizu, MD, PhD, Masayuki Yamamoto, MD, PhD, Hideo Harigae, MD, PhD

Blood (2015) 126 (23): 2382.

https://doi.org/10.1182/blood.V126.23.2382.2382

Published: 2015

Journal Articles

A Stress-Responsive Transcriptional Factor NRF2 Activates Hematopoietic Stem Cells

Murakami Shohei, PhD, Masayuki Yamamoto, MD PhD, Hozumi Motohashi, MD PhD

Blood (2015) 126 (23): 2351.

https://doi.org/10.1182/blood.V126.23.2351.2351

Published: 2015

Journal Articles

Keap1-Nrf2 System: Potential Role in Prevention of Sickle Cell Disease Organs Damages and Inflammation

Nadine Keleku-Lukwete, MD, Mikiko Suzuki, PhD, Akihito Otsuki, DDS, Kouhei Tsuchida, Saori Katayama, MD, Makiko Hayashi, Eriko Naganuma, Takashi Moriguchi, MDPhD, Osamu Tanabe, MDPhD, James Doug Engel, PhD, Masue Imaizumi, MDPhD, Masayuki Yamamoto, MD PhD

Blood (2015) 126 (23): 411.

https://doi.org/10.1182/blood.V126.23.411.411

Published: 2015

Journal Articles

GATA2 is critical for the maintenance of cellular identity in differentiated mast cells derived from mouse bone marrow

Shin’ya Ohmori, Takashi Moriguchi, Yuki Noguchi, Muneharu Ikeda, Kota Kobayashi, Nazuki Tomaru, Yasushi Ishijima, Osamu Ohneda, Masayuki Yamamoto, Kinuko Ohneda

Blood (2015) 125 (21): 3306–3315.

https://doi.org/10.1182/blood-2014-11-612465

Published: 2015

Includes: Supplemental data

Journal Articles

Forced HoxB4 Sustains CD45 - c-kit + Pre-Hematopoieitc Stem Cells (HSCs) Derived from Murine Induced-Pluripotent Stem Cells, Which Develop Long-Term and Short-Term Repopulating HSCs According to GATA2 Expression Level

Kiyoko Izawa, PhD, Tomoya Kakegawa, Master, Masayuki Yamamoto, MD PhD, Arinobu Tojo, MD PhD

Blood (2014) 124 (21): 1567.

https://doi.org/10.1182/blood.V124.21.1567.1567

Published: 2014

Journal Articles

Long-Term Ex Vivo Maintenance Of Murine iPSC-Derived Hematopoietic Stem/Progenitor Cells By Conditional HoxB4

Kiyoko Izawa, PhD, Masayuki Yamamoto, MD, PhD, Arinobu Tojo, MD, PhD.

Blood (2013) 122 (21): 2418.

https://doi.org/10.1182/blood.V122.21.2418.2418

Published: 2013

Journal Articles

The Gata1 5′ region harbors distinct cis -regulatory modules that direct gene activation in erythroid cells and gene inactivation in HSCs

Jun Takai, Takashi Moriguchi, Mikiko Suzuki, Lei Yu, Kinuko Ohneda, Masayuki Yamamoto

Blood (2013) 122 (20): 3450–3460.

https://doi.org/10.1182/blood-2013-01-476911

Published: 2013

Includes: Supplemental data

Journal Articles

Naturally occurring oncogenic GATA1 mutants with internal deletions in transient abnormal myelopoiesis in Down syndrome

Tsutomu Toki, Rika Kanezaki, Eri Kobayashi, Hiroshi Kaneko, Mikiko Suzuki, RuNan Wang, Kiminori Terui, Hirokazu Kanegane, Miho Maeda, Mikiya Endo, Tatsuki Mizuochi, Souichi Adachi, Yasuhide Hayashi, Masayuki Yamamoto, Ritsuko Shimizu, Etsuro Ito

Blood (2013) 121 (16): 3181–3184.

https://doi.org/10.1182/blood-2012-01-405746

Published: 2013

Includes: Supplemental data

Journal Articles

DNA Binding Diversity Achieved Through the Interaction of GATA1 N-Finger and GATA Motif Is Important for Embryonic Erythropoiesis

Atsushi Hasegawa, Ritsuko Shimizu, MD, PhD, Hirofumi Kurokawa, PhD, Masayuki Yamamoto, MD, PhD

Blood (2012) 120 (21): 3441.

https://doi.org/10.1182/blood.V120.21.3441.3441

Published: 2012

Journal Articles

Mature erythrocyte membrane homeostasis is compromised by loss of the GATA1-FOG1 interaction

Atsushi Hasegawa, Ritsuko Shimizu, Narla Mohandas, Masayuki Yamamoto

Blood (2012) 119 (11): 2615–2623.

https://doi.org/10.1182/blood-2011-09-382473

Published: 2012

Includes: Supplemental data

Journal Articles

Two Distinct Transactivation Domains of GATA1 Contribute Megakaryopoiesis,

Hiroshi Kaneko, Eri Kobayashi, MS, Ritsuko Shimizu, MD, PhD, Masayuki Yamamoto, MD, PhD

Blood (2011) 118 (21): 3384.

https://doi.org/10.1182/blood.V118.21.3384.3384

Published: 2011

Journal Articles

GATA1 Mutants Lacking Rb-Binding Motif Observed in Transient Abnormal Myelopoiesis in Down Syndrome

Tsutomu Toki, PhD, Eri Kobayashi, MS, Rika Kanezaki, MS, RuNan Wang, MD, Kiminori Terui, MD, PhD, Hirokazu Kanegane, MD, PhD, Miho Maeda, MD, PhD, Mikiya Endo, MD, PhD, Tatsuki Mizuochi, MD, PhD, Souichi Adachi, MD, PhD, Yasuhide Hayashi, MD, PhD, Ritsuko Shimizu, MD, PhD, Masayuki Yamamoto, MD, PhD, Etsuro Ito, MD, PhD

Blood (2011) 118 (21): 1491.

https://doi.org/10.1182/blood.V118.21.1491.1491

Published: 2011

Journal Articles

Heme regulates B-cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2

Miki Watanabe-Matsui, Akihiko Muto, Toshitaka Matsui, Ari Itoh-Nakadai, Osamu Nakajima, Kazutaka Murayama, Masayuki Yamamoto, Masao Ikeda-Saito, Kazuhiko Igarashi

Blood (2011) 117 (20): 5438–5448.

https://doi.org/10.1182/blood-2010-07-296483

Published: 2011

Journal Articles

Nrf2 and selenoproteins are essential for maintaining oxidative homeostasis in erythrocytes and protecting against hemolytic anemia

Yukie Kawatani, Takafumi Suzuki, Ritsuko Shimizu, Vincent P. Kelly, Masayuki Yamamoto

Blood (2011) 117 (3): 986–996.

https://doi.org/10.1182/blood-2010-05-285817

Published: 2011

Includes: Supplemental data

NARROW

An erythroid-to-myeloid cell fate conversion is elicited by LSD1 inactivation

How KEAP1 Deletion in Single Cell Mitigates Sickle Cell Pathology

Role of GATA2 in the Maintenance of the Bone Marrow Microenvironment

GATA2 haploinsufficiency accelerates EVI1-driven leukemogenesis

Specific Deletion of Keap1 in Endothelial Cells or/and Macrophages of SCD Mice Induces Nrf2 to Protect Tissues Against Oxidative Insults

GATA2 regulates dendritic cell differentiation

GATA-2 Regulates Dendritic Cell Differentiation

A Stress-Responsive Transcriptional Factor NRF2 Activates Hematopoietic Stem Cells

Keap1-Nrf2 System: Potential Role in Prevention of Sickle Cell Disease Organs Damages and Inflammation

GATA2 is critical for the maintenance of cellular identity in differentiated mast cells derived from mouse bone marrow

Forced HoxB4 Sustains CD45 - c-kit + Pre-Hematopoieitc Stem Cells (HSCs) Derived from Murine Induced-Pluripotent Stem Cells, Which Develop Long-Term and Short-Term Repopulating HSCs According to GATA2 Expression Level

Long-Term Ex Vivo Maintenance Of Murine iPSC-Derived Hematopoietic Stem/Progenitor Cells By Conditional HoxB4

The Gata1 5′ region harbors distinct cis -regulatory modules that direct gene activation in erythroid cells and gene inactivation in HSCs

Naturally occurring oncogenic GATA1 mutants with internal deletions in transient abnormal myelopoiesis in Down syndrome

DNA Binding Diversity Achieved Through the Interaction of GATA1 N-Finger and GATA Motif Is Important for Embryonic Erythropoiesis

Mature erythrocyte membrane homeostasis is compromised by loss of the GATA1-FOG1 interaction

Two Distinct Transactivation Domains of GATA1 Contribute Megakaryopoiesis,

GATA1 Mutants Lacking Rb-Binding Motif Observed in Transient Abnormal Myelopoiesis in Down Syndrome

Heme regulates B-cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2

Nrf2 and selenoproteins are essential for maintaining oxidative homeostasis in erythrocytes and protecting against hemolytic anemia

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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