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Journal Articles

TR4 and BCL11A Repress γ-globin Transcription via Independent Mechanisms

Yu Wang, Greggory Myers, Lei Yu, Kaiwen Deng, Ginette Balbin-Cuesta, Sharon A. Singh, Yuanfang Guan, Rami Khoriaty, James Douglas Engel

Blood blood.2024024599.

https://doi.org/10.1182/blood.2024024599

Published: 2024

Includes: Supplemental data

Journal Articles

Whole-Genome CRISPR-Cas9 Screening Identifies Genes Required for Human and Mouse Erythroid Development

Greggory Myers, Ann Friedman, Lei Yu, Claire Kerpet, Masaki Ito, Rilie Saba, Ginette Balbin-Cuesta, Zesen Lin, Claire Drysdale, Ayse Bilge Ozel, James Engel, Rami Khoriaty

Blood (2023) 142 (Supplement 1): 3828.

https://doi.org/10.1182/blood-2023-181929

Published: 2023

Journal Articles

Identifying Novel Regulators of γ-Globin Expression Using a Genome-Scale CRISPR Activation Screen

Ginette Balbin-Cuesta, Greggory Myers, Zesen Lin, Claire Kerpet, Beth McGee, Katherine Rybkin, Richard King, Claire Drysdale, Ann Friedman, Lei Yu, Masaki Ito, Rilie Saba, Ayse Bilge Ozel, Rami Khoriaty

Blood (2023) 142 (Supplement 1): 1100.

https://doi.org/10.1182/blood-2023-182203

Published: 2023

Journal Articles

Whole-Genome CRISPR-Cas9 Screen Identifies ZBTB7A As a Potential Therapeutic Target for Cda-II

Lei Yu, Greggory Myers, Beth McGee, Xiaofang Liu, Gallagher Patrick, Richard King, Ann Friedman, Ginette Balbin-Cuesta, Zesen Lin, Claire Drysdale, Claire Kerpet, Singh Sharon, James Engel, Rami Khoriaty

Blood (2023) 142 (Supplement 1): 12.

https://doi.org/10.1182/blood-2023-182246

Published: 2023

Journal Articles

Identification of CNOT4 As a Positive Regulator of Erythroid Cell Growth Using a Genome Wide CRISPR Knock-out Screen

Claire Drysdale, Greggory Myers, Lei Yu, Ann Friedman, Claire Kerpet, Ginette Balbin-Cuesta, Zesen Lin, Ayse Bilge Ozel, James Engel, Rami Khoriaty

Blood (2023) 142 (Supplement 1): 2447.

https://doi.org/10.1182/blood-2023-182187

Published: 2023

Journal Articles

A Genome Scale CRISPR Screen Identifies Novel Genes That Regulate Erythropoietin Production

Zesen Lin, Ginette Balbin-Cuesta, Greggory Myers, Lei Yu, Claire Drysdale, Vi Tang, Ayse Bilge Ozel, Ann Friedman, Beth McGee, Masaki Ito, Rilie Saba, Claire Kerpet, Richard King, Gallagher Patrick, James Engel, Rami Khoriaty

Blood (2023) 142 (Supplement 1): 3820.

https://doi.org/10.1182/blood-2023-182427

Published: 2023

Journal Articles

The CDK-Inhibitor p27 Kip1 Regulates Fetal Hemoglobin Expression

Ginette Balbin-Cuesta, Greggory Myers, Claire Kerpet, Beth McGee, Katherine Rybkin, Zesen Lin, Claire Drysdale, Ann Friedman, Sharon A Singh, Lei Yu, Ayse Bilge Ozel, Rami Khoriaty

Blood (2023) 142 (Supplement 1): 556.

https://doi.org/10.1182/blood-2023-181197

Published: 2023

Journal Articles

Disruption of the Malate-Aspartate Shuttle Leads to Anemia

Narges Pourmandi, Greggory Myers, Kelsey Temprine, Amanda Sankar, Noah Nelson, Yatrik Shah, Costas Lyssiotis, James Engel, Rami Khoriaty

Blood (2023) 142 (Supplement 1): 3823.

https://doi.org/10.1182/blood-2023-188220

Published: 2023

Journal Articles

Identification of Novel Regulators of Erythropoiesis Using Whole-Genome CRISPR-Cas9 Screening

Greggory Myers, Lei Yu, Ginette Balbin-Cuesta, Ayse Bilge Ozel, James Douglas Engel, Rami Khoriaty

Blood (2022) 140 (Supplement 1): 8155–8156.

https://doi.org/10.1182/blood-2022-170101

Published: 2022

Journal Articles

Identifying Novel Regulators of Erythroid Maturation and Proliferation Using a Genome-Scale CRISPR Activation Screen

Ginette Balbin-Cuesta, Katherine Rybkin, Greggory Myers, Rami Khoriaty

Blood (2022) 140 (Supplement 1): 8170–8171.

https://doi.org/10.1182/blood-2022-170108

Published: 2022

Journal Articles

p53-Independent Pathways in Diamond Blackfan Anemia

Kaiwen Deng, Lei Yu, Susan Hammoud, Alejandra Sanchez-Martinez, Xiaofang Liu, Ghazi-Abullah Saroya, Greggory Myers, Yu Wang, Ginette Balbin-Cuesta, Yuanfang Guan, Vesa Kaartinen, Rami Khoriaty, James Douglas Engel, Sharon A Singh

Blood (2022) 140 (Supplement 1): 11474.

https://doi.org/10.1182/blood-2022-165705

Published: 2022

Journal Articles

Identification of Critical Proteins Required for Efficient Von Willebrand Factor Secretion Using CRISPR Knockout Screening

Lauren Shevell, Krista Golden, Ginette Balbin-Cuesta, Rami Khoriaty, Brian Emmer, Karl Desch

Blood (2022) 140 (Supplement 1): 1672–1673.

https://doi.org/10.1182/blood-2022-162524

Published: 2022

Journal Articles

An erythroid-to-myeloid cell fate conversion is elicited by LSD1 inactivation

Lei Yu, Greggory Myers, Chia-Jui Ku, Emily Schneider, Yu Wang, Sharon A. Singh, Natee Jearawiriyapaisarn, Andrew White, Takashi Moriguchi, Rami Khoriaty, Masayuki Yamamoto, Michael G. Rosenfeld, Julien Pedron, John H. Bushweller, Kim-Chew Lim, James Douglas Engel

Blood (2021) 138 (18): 1691–1704.

https://doi.org/10.1182/blood.2021011682

Published: 2021

Includes: Supplemental data

Journal Articles

A Genome Scale CRISPR Screen Identifies the ER Cargo Receptor That Facilitates the Efficient Secretion of Erythropoietin

Zesen Lin, B.S., Greggory Myers, Beth McGee, Richard King, MD, Vi Tang, B.S., Ann Friedman, B.S., Brian Emmer, MD, Rami Khoriaty

Blood (2019) 134 (Supplement_1): 340.

https://doi.org/10.1182/blood-2019-131208

Published: 2019

Journal Articles

Functional Overlap between the SEC23 Paralogs Suggests a Novel Treatment Paradigm for Congenital Dyserythropoietic Anemia Type II

Richard King, MD, Ann Friedman, BS, Zesen Lin, BS, Rami Khoriaty, MD

Blood (2019) 134 (Supplement_1): 2221.

https://doi.org/10.1182/blood-2019-129669

Published: 2019

Journal Articles

Targeting Sec23b in COPII Vesicles Regulates T Cell Immunity

Stephanie Kim, BS, Rami Khoriaty, MD, Rajesh Valanparambil, PhD, Julia Wu, PhD, Austin Taylor, BS, Hideaki Fujiwara, MD, Dan Peltier, MD, Yaping Sun, MD PhD MS, Israel Henig, MD, Cynthia Zajac, Katherine Oravecz-Wilson, BS, MS, Stuart Brabbs, Rafi Ahmed, PhD, David Ginsburg, MD, Pavan Reddy, MD

Blood (2018) 132 (Supplement 1): 859.

https://doi.org/10.1182/blood-2018-99-111628

Published: 2018

Journal Articles

Overlap of SEC23A and SEC23B Function Suggests a Novel Therapeutic Approach for Congenital Dyserythropoietic Anemia Type II

Rami Khoriaty, MD, Angela Weyand, MD, Geoffrey Hesketh, PhD, Amélie Bernard, PhD, Lesley Everett, MD PhD, Guojing Zhu, MD, Beth McGee, Bin Zhang, PhD, Daniel Klionsky, PhD, Anne-Claude Gingras, Jordan A. Shavit, MD PhD, David Ginsburg, MD

Blood (2017) 130 (Supplement 1): 80.

https://doi.org/10.1182/blood.V130.Suppl_1.80.80

Published: 2017

Journal Articles

Mice with LMAN1 Deficiency Exhibit Thrombocytopenia and Reduced Serum Thrombopoietin Level

Rami Khoriaty, MD, Lesley Everett, BS, MPhil, Jennifer Chase, Guojing Zhu, Bin Zhang, PhD, Ivan Maillard, MD PhD, David Ginsburg, MD

Blood (2016) 128 (22): 412.

https://doi.org/10.1182/blood.V128.22.412.412

Published: 2016

Journal Articles

SEC23A Functionally Compensates for SEC23B Deficiency in Mice

Rami Khoriaty, MD, Lesley Everett, BS, MPhil, Jennifer Chase, Guojing Zhu, Bin Zhang, PhD, Mark Hoenerhoff, DVM, PhD DACVP, Ivan Maillard, MD PhD, David Ginsburg, MD

Blood (2015) 126 (23): 935.

https://doi.org/10.1182/blood.V126.23.935.935

Published: 2015

Journal Articles

TMEM16F Deficiency Causes a Strain-Dependent Lethality in Mice and Reduced Phosphatidylserine Exposure on Heterozygous As Well As Homozygous Deficient Mouse Platelets

Colin A Kretz, PhD, Valerie A Novakovic, M.S., Anna Kiseleva, Audrey C.A. Cleuren, PhD, Rami Khoriaty, MD, Elizabeth Adams, PhD, David Ginsburg, MD, Gary E. Gilbert, MD

Blood (2014) 124 (21): 4157.

https://doi.org/10.1182/blood.V124.21.4157.4157

Published: 2014

NARROW

TR4 and BCL11A Repress γ-globin Transcription via Independent Mechanisms

Whole-Genome CRISPR-Cas9 Screening Identifies Genes Required for Human and Mouse Erythroid Development

Identifying Novel Regulators of γ-Globin Expression Using a Genome-Scale CRISPR Activation Screen

Whole-Genome CRISPR-Cas9 Screen Identifies ZBTB7A As a Potential Therapeutic Target for Cda-II

Identification of CNOT4 As a Positive Regulator of Erythroid Cell Growth Using a Genome Wide CRISPR Knock-out Screen

A Genome Scale CRISPR Screen Identifies Novel Genes That Regulate Erythropoietin Production

The CDK-Inhibitor p27 Kip1 Regulates Fetal Hemoglobin Expression

Disruption of the Malate-Aspartate Shuttle Leads to Anemia

Identification of Novel Regulators of Erythropoiesis Using Whole-Genome CRISPR-Cas9 Screening

Identifying Novel Regulators of Erythroid Maturation and Proliferation Using a Genome-Scale CRISPR Activation Screen

p53-Independent Pathways in Diamond Blackfan Anemia

Identification of Critical Proteins Required for Efficient Von Willebrand Factor Secretion Using CRISPR Knockout Screening

An erythroid-to-myeloid cell fate conversion is elicited by LSD1 inactivation

A Genome Scale CRISPR Screen Identifies the ER Cargo Receptor That Facilitates the Efficient Secretion of Erythropoietin

Functional Overlap between the SEC23 Paralogs Suggests a Novel Treatment Paradigm for Congenital Dyserythropoietic Anemia Type II

Targeting Sec23b in COPII Vesicles Regulates T Cell Immunity

Overlap of SEC23A and SEC23B Function Suggests a Novel Therapeutic Approach for Congenital Dyserythropoietic Anemia Type II

Mice with LMAN1 Deficiency Exhibit Thrombocytopenia and Reduced Serum Thrombopoietin Level

SEC23A Functionally Compensates for SEC23B Deficiency in Mice

TMEM16F Deficiency Causes a Strain-Dependent Lethality in Mice and Reduced Phosphatidylserine Exposure on Heterozygous As Well As Homozygous Deficient Mouse Platelets

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American Society of Hematology

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American Society of Hematology

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