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Journal Articles

Differentiation of BCMA-specific induced pluripotent stem cells into rejuvenated CD8αβ + T cells targeting multiple myeloma

Jooeun Bae, Shuichi Kitayama, Zach Herbert, Laurence Daheron, Keiji Kurata, Derin B. Keskin, Kenneth Livak, Shuqiang Li, Mubin Tarannum, Rizwan Romee, Mehmet Samur, Nikhil C. Munshi, Shin Kaneko, Jerome Ritz, Kenneth C. Anderson

Blood (2024) 143 (10): 895–911.

https://doi.org/10.1182/blood.2023020528

Published: 2024

Includes: Supplemental data

Journal Articles

iPSC-Derived HLA-A2 CAR Tregs Showed Suppression of GvHD in a Xenograft Model

Hisashi Yano, Takayuki Sato, Tokuyuki Shinohara, Keiko Koga, Shoichi Iriguchi, Atsushi Matsuda, Yasuyuki Miyake, Yoshiaki Kassai, Hitoshi Kiyoi, Shin Kaneko

Blood (2022) 140 (Supplement 1): 2365–2366.

https://doi.org/10.1182/blood-2022-156904

Published: 2022

Journal Articles

Rejuvenated BCMA-Specific CD8 + Cytotoxic T Lymphocytes Derived from Antigen-Specific Induced Pluripotent Stem Cells : Immunotherapeutic Application in Multiple Myeloma

Jooeun Bae, Shuichi Kitayama, Laurence Daheron, Zach Herbert, Nikhil C. Munshi, Shin Kaneko, Jerome Ritz, Kenneth C. Anderson

Blood (2021) 138 (Supplement 1): 75.

https://doi.org/10.1182/blood-2021-153110

Published: 2021

Journal Articles

Guided Polarization of iPSC-Derived CD4SP Helper T Cells By CRISPR/Cas9-Based Genome-Editing

Hisashi Yano, MD, Tokuyuki Shinohara, PhD, Keiko Koga, PhD, Shoichi Iriguchi, PhD, Yasuyuki Miyake, Xuewei Song, Megumi Tada, Yoshiaki Kassai, PhD, Hitoshi Kiyoi, MD PhD, Shin Kaneko, MD PhD

Blood (2019) 134 (Supplement_1): 1937.

https://doi.org/10.1182/blood-2019-122193

Published: 2019

Journal Articles

Junctional Adhesion Molecule 2 Intensifies T Lymphopoiesis of Hematopoietic Stem Cells By Facilitating Notch/Delta Signaling

Visnja Radulovic, PhD, Mark Van Der Garde, PhD, Valgardur Sigurdsson, PhD, Alya Zriwil, PhD, Svetlana Soboleva, Ewa Sitnicka Quinn, PhD, Shin Kaneko, MD PhD, Kenichi Miharada, PhD

Blood (2017) 130 (Supplement 1): 635.

https://doi.org/10.1182/blood.V130.Suppl_1.635.635

Published: 2017

Journal Articles

Junctional Adhesion Molecule 2 Represents a Novel Subset of Hematopoietic Stem Cells Poised for T Lymphopoiesis

Visnja Radulovic, PhD, Mark van der Garde, PhD, Valgardur Sigurdsson, PhD, Alya Zriwil, Svetlana Soboleva, Shin Kaneko, MD PhD, Ewa Sitnicka Quinn, PhD, Kenichi Miharada, PhD

Blood (2016) 128 (22): 3862.

https://doi.org/10.1182/blood.V128.22.3862.3862

Published: 2016

Journal Articles

Generation of BCR-ABL Reactive CD4+ T Helper Cells By Reprograming and Redifferentiation

Norihiro Ueda, MD, Yasusi Uemura, PhD, Rhong Zhang, MD PhD, Shuichi Kitayama, Yutaka Yasui, Minako Tatsumi, Tian-Yi Liu, MD PhD, Kiyotaka Kuzushima, MD PhD, Hitoshi Kiyoi, MD PhD, Tomoki Naoe, MD PhD, Shin Kaneko, MD PhD

Blood (2015) 126 (23): 3424.

https://doi.org/10.1182/blood.V126.23.3424.3424

Published: 2015

Journal Articles

T-cell–restricted T-bet overexpression induces aberrant hematopoiesis of myeloid cells and impairs function of macrophages in the lung

Shoichi Iriguchi, Norihiro Kikuchi, Shin Kaneko, Emiko Noguchi, Yuko Morishima, Masashi Matsuyama, Keigyou Yoh, Satoru Takahashi, Hiromitsu Nakauchi, Yukio Ishii

Blood (2015) 125 (2): 370–382.

https://doi.org/10.1182/blood-2014-05-575225

Published: 2015

Includes: Supplemental data

Journal Articles

Modeling Congenital Amegakaryocytic Thrombocytopenia Using Patient-Specific Induced Pluripotent Stem Cells

Naoya Takayama, M.D., Ph.D., Shinji Hirata, Ryoko Jono-Ohnishi, Sou Nakamura, Sho-ichi Hirose, Hiroshi Endo, M.D., Masanori Nishi, MD, Yuhei Hamazaki, Shin Kaneko, M.D., Ph.D., Eiichi Ishii, MD, PhD, Hiromitsu Nakauchi, MD, PhD, Shinji Kunishima, PhD, Koji Eto, M.D., Ph.D.

Blood (2011) 118 (21): 703.

https://doi.org/10.1182/blood.V118.21.703.703

Published: 2011

Journal Articles

In Vitro Generation of Mature T Lymphocytes From Human Ips Cells and Genetic Analysis of TCR Gene Rearrangements

Toshinobu Nishimura, Shin Kaneko, M.D., Ph.D., Yoko Tajima, Naoya Takayama, M.D., Ph.D., Ai Tachikawa-Kawana, Ph.D., Koji Eto, M.D., Ph.D., Hiromitsu Nakauchi, MD, PhD

Blood (2011) 118 (21): 2984.

https://doi.org/10.1182/blood.V118.21.2984.2984

Published: 2011

Journal Articles

IL-7 receptor expression identifies suicide gene–modified allospecific CD8 + T cells capable of self-renewal and differentiation into antileukemia effectors

Attilio Bondanza, Lothar Hambach, Zohara Aghai, Bart Nijmeijer, Shin Kaneko, Sara Mastaglio, Marina Radrizzani, Katharina Fleischhauer, Fabio Ciceri, Claudio Bordignon, Chiara Bonini, Els Goulmy

Blood (2011) 117 (24): 6469–6478.

https://doi.org/10.1182/blood-2010-11-320366

Published: 2011

Includes: Supplemental data

Journal Articles

Generation of Monoclonal TCR-Expressing Human T-Lineage Lymphocytes From Induced Pluripotent Stem Cells of Single Peripheral T-Lymphocyte Origin

Toshinobu Nishimura, Shin Kaneko, M.D., Ph.D., Haruo Gotoh, Naoya Takayama, M.D., Ph.D., Takafumi Shimizu, Shoichi Iriguchi, Yoko Tajima, Yutaka Yasui, Nobukazu Watanabe, M.D., Ph.D., Satoshi Takahashi, M.D., Ph.D., Koji Eto, M.D., Ph.D., Hiromitsu Nakauchi, M.D., Ph.D.

Blood (2010) 116 (21): 490.

https://doi.org/10.1182/blood.V116.21.490.490

Published: 2010

Journal Articles

Establishment of Mouse PMF Model by the Introduction of Constitutive STAT5a Into Purified Hematopoietic Stem Cells.

Takafumi Shimizu, Akihiko Ito, Akira Nakagawa, Toshinobu Nishimura, Satoshi Yamazaki, Shoichi Iriguchi, Shin Kaneko, Hiromitsu Nakauchi

Blood (2009) 114 (22): 3900.

https://doi.org/10.1182/blood.V114.22.3900.3900

Published: 2009

Journal Articles

IL-7 and IL-15 allow the generation of suicide gene–modified alloreactive self-renewing central memory human T lymphocytes

Shin Kaneko, Sara Mastaglio, Attilio Bondanza, Maurilio Ponzoni, Francesca Sanvito, Luca Aldrighetti, Marina Radrizzani, Simona La Seta-Catamancio, Elena Provasi, Anna Mondino, Toshiro Nagasawa, Katharina Fleischhauer, Vincenzo Russo, Catia Traversari, Fabio Ciceri, Claudio Bordignon, Chiara Bonini

Blood (2009) 113 (5): 1006–1015.

https://doi.org/10.1182/blood-2008-05-156059

Published: 2009

Journal Articles

Requirements for Retroviral Targeting of a Suicide Gene to Alloreactive Memory Stem T Cells for Adoptive Immunotherapy of Leukemia.

Attilio Bondanza, MD, PhD, Lothar Hambach, MD, Shin Kaneko, MD, PhD, Sara Mastaglio, MD, Bart Nijmeijer, PhD, Astrid Van Halteren, PhD, Maurilio Ponzoni, MD, Luca Aldrighetti, MD, Salvatore Toma, PhD, Marina Radrizzani, BSc, Fabio Ciceri, MD, Claudio Bordignon, MD, Els Goulmy, PhD, Chiara Bonini, MD

Blood (2007) 110 (11): 2176.

https://doi.org/10.1182/blood.V110.11.2176.2176

Published: 2007

Journal Articles

High Alloreactive Potential of Central Memory T-Lymphocytes Expressing a Suicide Gene for the Cure of Hematologic Malignancies.

Shin Kaneko, MD, PhD, Sara Mastaglio, MD, Attilio Bondanza, MD, Maurilio Ponzoni, MD, Luca Aldrighetti, MD, Salvatore Toma, PhD, Marina Radrizzani, PhD, Simona La Seta Catamancio, PhD, Fabio Ciceri, MD, Toshiro Nagasawa, MD,PhD, Claudio Bordignon, MD,PhD, Chiara Bonini, MD

Blood (2006) 108 (11): 3265.

https://doi.org/10.1182/blood.V108.11.3265.3265

Published: 2006

Journal Articles

Rapid and Wide Immunereconstitution Obtained with HSV-TK Engineered Donor Lymphocyte Add-Backs Permits Long-Term Survival after haplo-HSCT.

Blood (2006) 108 (11): 307.

https://doi.org/10.1182/blood.V108.11.307.307

Published: 2006

Journal Articles

Suicide Gene Therapy of Graft-Versus-Host Disease Induced by Central Memory Human T Lymphocytes.

Attilio Bondanza, MD, Veronica Valtolina, BSc, Zulma Magnani, BSc, Shin Kaneko, MD, PhD, Maurilio Ponzoni, MD, Francesca Sanvito, MD, Mark Bonyhadi, PhD, Catia Traversari, PhD, Salvatore Toma, PhD, Marina Radrizzani, BSc, Simona La Seta-Catamancio, BSc, Katharina Fleischhauer, MD, Fabio Ciceri, MD, Claudio Bordignon, MD, Chiara Bonini, MD

Blood (2005) 106 (11): 3096.

https://doi.org/10.1182/blood.V106.11.3096.3096

Published: 2005

Journal Articles

Erythroid expansion mediated by the Gfi-1B zinc finger protein: role in normal hematopoiesis

Mitsujiro Osawa, Tomoyuki Yamaguchi, Yukio Nakamura, Shin Kaneko, Masafumi Onodera, Ken-ichi Sawada, Armin Jegalian, Hong Wu, Hiromitsu Nakauchi, Atsushi Iwama

Blood (2002) 100 (8): 2769–2777.

https://doi.org/10.1182/blood-2002-01-0182

Published: 2002

Journal Articles

Fas-Independent and Nonapoptotic Cytotoxicity Mediated by a Human CD4 + T-Cell Clone Directed Against an Acute Myelogenous Leukemia–Associated DEK-CAN Fusion Peptide

Hideki Ohminami, Masaki Yasukawa, Shin Kaneko, Yoshihiro Yakushijin, Yasuhito Abe, Yoshihito Kasahara, Yasushi Ishida, Shigeru Fujita

Blood (1999) 93 (3): 925–935.

https://doi.org/10.1182/blood.V93.3.925

Published: 1999

NARROW

Differentiation of BCMA-specific induced pluripotent stem cells into rejuvenated CD8αβ + T cells targeting multiple myeloma

iPSC-Derived HLA-A2 CAR Tregs Showed Suppression of GvHD in a Xenograft Model

Rejuvenated BCMA-Specific CD8 + Cytotoxic T Lymphocytes Derived from Antigen-Specific Induced Pluripotent Stem Cells : Immunotherapeutic Application in Multiple Myeloma

Guided Polarization of iPSC-Derived CD4SP Helper T Cells By CRISPR/Cas9-Based Genome-Editing

Junctional Adhesion Molecule 2 Intensifies T Lymphopoiesis of Hematopoietic Stem Cells By Facilitating Notch/Delta Signaling

Junctional Adhesion Molecule 2 Represents a Novel Subset of Hematopoietic Stem Cells Poised for T Lymphopoiesis

Generation of BCR-ABL Reactive CD4+ T Helper Cells By Reprograming and Redifferentiation

T-cell–restricted T-bet overexpression induces aberrant hematopoiesis of myeloid cells and impairs function of macrophages in the lung

Modeling Congenital Amegakaryocytic Thrombocytopenia Using Patient-Specific Induced Pluripotent Stem Cells

In Vitro Generation of Mature T Lymphocytes From Human Ips Cells and Genetic Analysis of TCR Gene Rearrangements

IL-7 receptor expression identifies suicide gene–modified allospecific CD8 + T cells capable of self-renewal and differentiation into antileukemia effectors

Generation of Monoclonal TCR-Expressing Human T-Lineage Lymphocytes From Induced Pluripotent Stem Cells of Single Peripheral T-Lymphocyte Origin

Establishment of Mouse PMF Model by the Introduction of Constitutive STAT5a Into Purified Hematopoietic Stem Cells.

IL-7 and IL-15 allow the generation of suicide gene–modified alloreactive self-renewing central memory human T lymphocytes

Requirements for Retroviral Targeting of a Suicide Gene to Alloreactive Memory Stem T Cells for Adoptive Immunotherapy of Leukemia.

High Alloreactive Potential of Central Memory T-Lymphocytes Expressing a Suicide Gene for the Cure of Hematologic Malignancies.

Rapid and Wide Immunereconstitution Obtained with HSV-TK Engineered Donor Lymphocyte Add-Backs Permits Long-Term Survival after haplo-HSCT.

Suicide Gene Therapy of Graft-Versus-Host Disease Induced by Central Memory Human T Lymphocytes.

Erythroid expansion mediated by the Gfi-1B zinc finger protein: role in normal hematopoiesis

Fas-Independent and Nonapoptotic Cytotoxicity Mediated by a Human CD4 + T-Cell Clone Directed Against an Acute Myelogenous Leukemia–Associated DEK-CAN Fusion Peptide

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American Society of Hematology

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American Society of Hematology

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