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Journal Articles

A First-in-Human Study of YTB323, a Novel, Autologous CD19-Directed CAR-T Cell Therapy Manufactured Using the Novel T-Charge TM platform, for the Treatment of Patients (Pts) with Relapsed/Refractory (r/r) Diffuse Large B-Cell Lymphoma (DLBCL)

Blood (2021) 138 (Supplement 1): 740.

https://doi.org/10.1182/blood-2021-146268

Published: 2021

Journal Articles

Ibrutinib before Apheresis May Improve Tisagenlecleucel Manufacturing in Relapsed/Refractory Adult Diffuse Large B-Cell Lymphoma: Initial Results from a Phase 1b Study

Julio C. Chavez, MD, Frederick L. Locke, MD, Ellen Napier, CRNP, Carl Simon, MS, Andrew Lewandowski, PhD, Rakesh Awasthi, PhD, Boris Engels, PhD, Petrina Georgala, PhD, Attilio Bondanza, MD, Stephen J. Schuster, MD

Blood (2020) 136 (Supplement 1): 3–4.

https://doi.org/10.1182/blood-2020-134270

Published: 2020

Journal Articles

Combining De-Glycosylating Agents with CAR-T Cells for Targeting Solid Tumors and Reducing Toxicity

Beatrice Greco, MSc, Katia Paolella, Barbara Camisa, Valeria Malacarne, PhD, Laura Falcone, Andrea Graziani, PhD, Chiara Bonini, MD, Attilio Bondanza, MD, Monica Casucci, PhD

Blood (2018) 132 (Supplement 1): 4544.

https://doi.org/10.1182/blood-2018-99-116019

Published: 2018

Journal Articles

Exhausted Central Memory and Memory Stem T Cells Specific for Leukemia Infiltrate the Bone Marrow of AML Patients Relapsing after Allogeneic HSCT

Francesco Manfredi, MD, Maddalena Noviello, PhD, Eliana Ruggiero, PhD, Tommaso Perini, MD, Giacomo Oliveira, PhD, Filippo Cortesi, PhD, Pantaleo De Simone, MD, Cristina Toffalori, Valentina Gambacorta, MSc, Raffaella Greco, MD, Jacopo Peccatori, Monica Casucci, PhD, Giulia Casorati, PhD, Paolo Dellabona, MD PhD, Nicoletta Cieri, MD PhD, Attilio Bondanza, MD, Luca Vago, MD PhD, Fabio Ciceri, MD, Chiara Bonini, MD

Blood (2018) 132 (Supplement 1): 2028.

https://doi.org/10.1182/blood-2018-99-118104

Published: 2018

Journal Articles

Early and Profound Exhausted Phenotype of Central Memory and Memory Stem T Cells in the Bone Marrow of AML Patients Characterizes and Predicts Relapse after Allo-HSCT

Maddalena Noviello, PhD, Francesco Manfredi, MD, Tommaso Perini, MD, Oliveira Giacomo, PhD, Filippo Cortesi, PhD, Pantaleo De Simone, MD, Cristina Toffalori, PhD, Valentina Gambacorta, MSc, Attilio Bondanza, MD, Raffaella Greco, MD, Jacopo Peccatori, MD, Giulia Casorati, PhD, Paolo Dellabona, MD PhD, Nicoletta Cieri, MD PhD, Luca Vago, MD PhD, Fabio Ciceri, MD, Chiara Bonini, MD

Blood (2017) 130 (Supplement 1): 4491.

https://doi.org/10.1182/blood.V130.Suppl_1.4491.4491

Published: 2017

Journal Articles

NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease

Blood (2017) 130 (5): 606–618.

https://doi.org/10.1182/blood-2016-08-732636

Published: 2017

Includes: Supplemental data

Journal Articles

Mother Donors Improve Outcomes after HLA Haploidentical Hematopoietic Transplantation: A Retrospective Study By the Cell Therapy and Immunobiology Working Party of the EBMT

Blood (2016) 128 (22): 3472.

https://doi.org/10.1182/blood.V128.22.3472.3472

Published: 2016

Journal Articles

Monocytes Are Required for Both Optimal Anti-Leukemic Efficacy and the Cytokine Release Syndrome By CAR-T Cells: Lessons from an Innovative Xenotolerant Mouse Model

Margherita Norelli, MSc, Monica Casucci, PhD, Barbara Camisa, BSc, Laura Falcone, MSc, Catia Traversari, PhD, Claudio Bordignon, MD, Fabio Ciceri, MD, Chiara Bonini, MD, Attilio Bondanza, MD PhD

Blood (2016) 128 (22): 997.

https://doi.org/10.1182/blood.V128.22.997.997

Published: 2016

Journal Articles

Pre-Transplant Colonization By a Multidrug-Resistant Gram Negative Bacteria Has No Impact on Overall Survival and Mortality after Hematopoietic Stem Cell Transplantation: A Single-Center Experience in 362 Patients

Vincenzo Marasco, MD, Alessandra Forcina, MD, Francesca Lorentino, MD, Raffaella Greco, MD, Mara Morelli, MD, Fabio Giglio, MD, Carlo Messina, MD, Maria Teresa Lupo Stanghellini, MD, Carrabba Matteo, MD, Magda Marcatti, MD, Attilio Bondanza, MD PhD, Massimo Bernardi, MD, Jacopo Peccatori, MD, Consuelo Corti, MD, Fabio Ciceri, MD

Blood (2016) 128 (22): 5743.

https://doi.org/10.1182/blood.V128.22.5743.5743

Published: 2016

Journal Articles

How to Monitor Immune Reconstitution Following Allogeneic Hematopoietic Stem Cell Transplantation: A Survey from the EBMT- Cellular Therapy & Immunobiology Working Party

Raffaella Greco, MD, Fabio Ciceri, MD, Maddalena Noviello, PhD, Attilio Bondanza, MD PhD, Luca Vago, MD PhD, Giacomo Oliveira, PhD, Jacopo Peccatori, MD, Nicoletta Cieri, MD PhD, Annalisa Ruggeri, Ulrike Koehl, Katharina Fleischhauer, MD, Vanderson Rocha, MD PhD, Francesco Dazzi, PhD, Steffie Maria van der Werf, Sofie Rosanne Terwel, Antoine Toubert, Christian Chabannon, MD PhD, Chiara Bonini, MD

Blood (2016) 128 (22): 4581.

https://doi.org/10.1182/blood.V128.22.4581.4581

Published: 2016

Journal Articles

Impact of Immune Reconstitution (IR) and Graft-Versus-Host Disease (GvHD) on Clinical Outcomes after Treatment with Donor T Cells Transduced to Express the Herpes Simplex Virus Thymidine-Kinase Suicide Gene (TK cells) in Acute Leukemia Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplantation (HSCT)

Blood (2016) 128 (22): 4599.

https://doi.org/10.1182/blood.V128.22.4599.4599

Published: 2016

Journal Articles

Infection-Related Mortality (IRM) after Allogeneic Hematopoietic Stem Cell Transplantation: Age, CMV Status, Pre-Transplant IgA and IgM Levels Predict IRM and Survival in a New Clinico-Biological Scoring System Developed in 492 Consecutive Patients

Alessandra Forcina, MD, Paola Maria Vittoria Rancoita, Vincenzo Marasco, MD, Raffaella Greco, MD, Maria Teresa Lupo-Stanghellini, MD, Matteo Giovanni Carrabba, MD, Marcatti Magda, MD, Clelia Di Serio, Massimo Bernardi, MD, Jacopo Peccatori, MD, Consuelo Corti, MD, Attilio Bondanza, MD PhD, Fabio Ciceri, MD

Blood (2016) 128 (22): 2220.

https://doi.org/10.1182/blood.V128.22.2220.2220

Published: 2016

Journal Articles

Multiple Inhibitory Receptors Are Expressed on Central Memory and Memory Stem T Cells Infiltrating the Bone Marrow of AML Patients Relapsing after Allo-HSCT

Maddalena Noviello, PhD, Francesco Manfredi, Tommaso Perini, MD, Giacomo Oliveira, PhD, Filippo Cortesi, PhD, Cristina Toffalori, PhD, Valentina Gambacorta, MSc, Attilio Bondanza, MD PhD, Raffaella Greco, MD, Jacopo Peccatori, MD, Giulia Casorati, PhD, Paolo Dellabona, PhD, Nicoletta Cieri, MD PhD, Luca Vago, MD PhD, Fabio Ciceri, MD, Chiara Bonini, MD

Blood (2016) 128 (22): 4564.

https://doi.org/10.1182/blood.V128.22.4564.4564

Published: 2016

Journal Articles

Clinical and Biological Features Associated with Engraftment of Acute Myeloid Leukemia Patient-Derived Xenografts

Giacomo Oliveira, PhD, Gabriele Bucci, PhD, Cristina Toffalori, PhD, Carolina Caserta, Lara Crucitti, MD, Barbara Camisa, BSc, Raffaella Greco, MD, Francesca Biavasco, Lucia Zanotti, PhD, Laura Zito, MSc, Jose Manuel Garcia-Manteiga, PhD, Dejan Lazarevic, MD, Matteo Giovanni Carrabba, MD, Massimo Bernardi, MD, Attilio Bondanza, MD PhD, Chiara Bonini, MD, Fabio Ciceri, MD, Luca Vago, MD PhD

Blood (2016) 128 (22): 2858.

https://doi.org/10.1182/blood.V128.22.2858.2858

Published: 2016

Journal Articles

An Accelerated CD8+, but Not CD4+, T-Cell Reconstitution Associates with a More Favorable Outcome Following HLA-Haploidentical HSCT: Results from a Retrospective Study of the Cell Therapy and Immunobiology Working Party of the EBMT

Blood (2015) 126 (23): 1929.

https://doi.org/10.1182/blood.V126.23.1929.1929

Published: 2015

Journal Articles

Tracking Genetically Engineered Lymphocytes Long-Term Reveals the Dynamics of T-Cell Immunological Memory

Blood (2015) 126 (23): 263.

https://doi.org/10.1182/blood.V126.23.263.263

Published: 2015

Journal Articles

Generation of human memory stem T cells after haploidentical T-replete hematopoietic stem cell transplantation

Nicoletta Cieri, Giacomo Oliveira, Raffaella Greco, Mattia Forcato, Cristian Taccioli, Beatrice Cianciotti, Veronica Valtolina, Maddalena Noviello, Luca Vago, Attilio Bondanza, Francesca Lunghi, Sarah Marktel, Laura Bellio, Claudio Bordignon, Silvio Bicciato, Jacopo Peccatori, Fabio Ciceri, Chiara Bonini

Blood (2015) 125 (18): 2865–2874.

https://doi.org/10.1182/blood-2014-11-608539

Published: 2015

Includes: Supplemental data

Journal Articles

Revealing the Generation of Human Memory Stem T Cells in Haploidentical T-Replete Hematopoietic Stem Cell Transplantation

Nicoletta Cieri, MD PhD, Giacomo Oliveira, MSc, Raffaella Greco, MD, Mattia Forcato, PhD, Cristian Taccioli, PhD, Veronica Valtolina, MSc, Maddalena Noviello, PhD, Luca Vago, MD PhD, Attilio Bondanza, MD PhD, Francesca Lunghi, MD, Sarah Marktel, MD, Laura Bellio, MD, Claudio Bordignon, MD, Silvio Bicciato, PhD, Jacopo Peccatori, MD, Fabio Ciceri, MD, Chiara Bonini, MD

Blood (2014) 124 (21): 192.

https://doi.org/10.1182/blood.V124.21.192.192

Published: 2014

Journal Articles

Long-Term Immunological Profile of Patients Treated with Haploidentical HSCT and TK-Cells to Study the Requirements of Memory T Cell Persistence

Giacomo Oliveira, MSc, Maria Teresa Lupo Stanghellini, MD, Eliana Ruggiero, PhD, Nicoletta Cieri, MD PhD, Mattia D'Agostino, MD, Raffaella Greco, MD, Sara Mastaglio, MD, Maddalena Noviello, PhD, Luca Vago, MD PhD, Luca Biasco, PhD, Attilio Bondanza, MD PhD, Alessandro Aiuti, MD, Antonio Lambiase, MD, Manfred Schmidt, PhD, Catia Traversari, PhD, Christof von Kalle, MD, Fabio Ciceri, MD, Claudio Bordignon, MD, Chiara Bonini, MD

Blood (2014) 124 (21): 4793.

https://doi.org/10.1182/blood.V124.21.4793.4793

Published: 2014

Journal Articles

Infusion of Donor Lymphocytes Genetically Engineered to Express the Herpes Simplex Virus Thymidine Kinase (HSV-TK) Suicide Gene after Haploidentical Hematopoietic Stem Cell Transplantation (HSCT): Preliminary Efficacy Data from the Randomized TK008 Study

Blood (2014) 124 (21): 2535.

https://doi.org/10.1182/blood.V124.21.2535.2535

Published: 2014

NARROW

A First-in-Human Study of YTB323, a Novel, Autologous CD19-Directed CAR-T Cell Therapy Manufactured Using the Novel T-Charge TM platform, for the Treatment of Patients (Pts) with Relapsed/Refractory (r/r) Diffuse Large B-Cell Lymphoma (DLBCL)

Ibrutinib before Apheresis May Improve Tisagenlecleucel Manufacturing in Relapsed/Refractory Adult Diffuse Large B-Cell Lymphoma: Initial Results from a Phase 1b Study

Combining De-Glycosylating Agents with CAR-T Cells for Targeting Solid Tumors and Reducing Toxicity

Exhausted Central Memory and Memory Stem T Cells Specific for Leukemia Infiltrate the Bone Marrow of AML Patients Relapsing after Allogeneic HSCT

Early and Profound Exhausted Phenotype of Central Memory and Memory Stem T Cells in the Bone Marrow of AML Patients Characterizes and Predicts Relapse after Allo-HSCT

NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease

Mother Donors Improve Outcomes after HLA Haploidentical Hematopoietic Transplantation: A Retrospective Study By the Cell Therapy and Immunobiology Working Party of the EBMT

Monocytes Are Required for Both Optimal Anti-Leukemic Efficacy and the Cytokine Release Syndrome By CAR-T Cells: Lessons from an Innovative Xenotolerant Mouse Model

Pre-Transplant Colonization By a Multidrug-Resistant Gram Negative Bacteria Has No Impact on Overall Survival and Mortality after Hematopoietic Stem Cell Transplantation: A Single-Center Experience in 362 Patients

How to Monitor Immune Reconstitution Following Allogeneic Hematopoietic Stem Cell Transplantation: A Survey from the EBMT- Cellular Therapy & Immunobiology Working Party

Infection-Related Mortality (IRM) after Allogeneic Hematopoietic Stem Cell Transplantation: Age, CMV Status, Pre-Transplant IgA and IgM Levels Predict IRM and Survival in a New Clinico-Biological Scoring System Developed in 492 Consecutive Patients

Multiple Inhibitory Receptors Are Expressed on Central Memory and Memory Stem T Cells Infiltrating the Bone Marrow of AML Patients Relapsing after Allo-HSCT

Clinical and Biological Features Associated with Engraftment of Acute Myeloid Leukemia Patient-Derived Xenografts

An Accelerated CD8+, but Not CD4+, T-Cell Reconstitution Associates with a More Favorable Outcome Following HLA-Haploidentical HSCT: Results from a Retrospective Study of the Cell Therapy and Immunobiology Working Party of the EBMT

Tracking Genetically Engineered Lymphocytes Long-Term Reveals the Dynamics of T-Cell Immunological Memory

Generation of human memory stem T cells after haploidentical T-replete hematopoietic stem cell transplantation

Revealing the Generation of Human Memory Stem T Cells in Haploidentical T-Replete Hematopoietic Stem Cell Transplantation

Long-Term Immunological Profile of Patients Treated with Haploidentical HSCT and TK-Cells to Study the Requirements of Memory T Cell Persistence

Infusion of Donor Lymphocytes Genetically Engineered to Express the Herpes Simplex Virus Thymidine Kinase (HSV-TK) Suicide Gene after Haploidentical Hematopoietic Stem Cell Transplantation (HSCT): Preliminary Efficacy Data from the Randomized TK008 Study

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American Society of Hematology

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American Society of Hematology

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