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Journal Articles

Efficacy and Safety of Venetoclax in Combination with Azacitidine for the Treatment of Patients with Treatment-Naive, Higher-Risk Myelodysplastic Syndromes

Jacqueline S. Garcia, Uwe Platzbecker, Olatoyosi Odenike, Shaun Fleming, Chun Yew Fong, Rachel Cook, Meagan Jacoby, Daniel Nowak, Brenda Chyla, Ying Zhou, Grace Ku, Jalaja Potluri, Guillermo Garcia-Manero

Blood (2023) 142 (Supplement 1): 319.

https://doi.org/10.1182/blood-2023-189446

Published: 2023

Journal Articles

Instructive Interaction between Myelodysplastic Hematopoiesis and the Bone Marrow Microenvironment at Single Cell Level

Blood (2023) 142 (Supplement 1): 3217.

https://doi.org/10.1182/blood-2023-186130

Published: 2023

Journal Articles

Distinct and Targetable Role of Calcium and Calcium Sensing Receptor in Leukaemia

Blood (2023) 142 (Supplement 1): 5709.

https://doi.org/10.1182/blood-2023-177990

Published: 2023

Journal Articles

The Novel Bispecific Innate Cell Engager (ICE®) AFM28 Efficiently Directs Allogeneic NK Cells to CD123+ Leukemic Stem- and Progenitor Cells in AML

Nanni Schmitt, Jana-Julia Siegler, Lena Wagner, Nicole Schulze, Alexandra Beck, Wolf-Karsten Hofmann, Torsten Haneke, Uwe Reusch, José Medina-Echeverz, Jan Endell, Thorsten Ross, Christian Merz, Daniel Nowak

Blood (2022) 140 (Supplement 1): 8815–8816.

https://doi.org/10.1182/blood-2022-169729

Published: 2022

Journal Articles

ASXL1 Mutations Are Associated with a Response to the Combination of Alvocidib and 5-Azacytidine in Higher-Risk Myelodysplastic Syndromes

Blood (2022) 140 (Supplement 1): 9749–9750.

https://doi.org/10.1182/blood-2022-165298

Published: 2022

Journal Articles

Inter-Modality Variance of Blast Quantification in Patients with Myelodysplastic Syndrome (MDS) and Its Impact on Risk Stratification and Overall Survival

Laurenz Steiner, Navkirandeep Kaur, Alexander Streuer, Johann-Christoph Jann, Alice Fabarius, Georgia Metzgeroth, Wolf-Karsten Hofmann, Daniel Nowak, Mohamad Jawhar

Blood (2022) 140 (Supplement 1): 9831–9832.

https://doi.org/10.1182/blood-2022-168850

Published: 2022

Journal Articles

Inhibition of Lysyl Oxidases Synergizes with 5-Azacytidine to Restore Erythropoiesis in Myeloid Neoplasms

Blood (2022) 140 (Supplement 1): 3054–3055.

https://doi.org/10.1182/blood-2022-159507

Published: 2022

Journal Articles

Direct Comparison of NSG and NBSGW Mice for MDS Patient-Derived Xenograft Models

Nanni Schmitt, Alexander Streuer, Justine Danner, Eva Altrock, Vladimir Riabov, Qingyu Xu, Felicitas Rapp, Nadine Weimer, Iris Palme, Verena Nowak, Julia Obländer, Melda Göl, Ali Darwich, Laurenz Steiner, Tobias Boch, Mohamad Jawhar, Georgia Metzgeroth, Wolf-Karsten Hofmann, Daniel Nowak

Blood (2022) 140 (Supplement 1): 4009–4010.

https://doi.org/10.1182/blood-2022-168709

Published: 2022

Journal Articles

Molecular Responses Are Observed across Mutational Spectrum in Treatment-Naïve Higher-Risk Myelodysplastic Syndrome Patients Treated with Venetoclax Plus Azacitidine

Blood (2021) 138 (Supplement 1): 241.

https://doi.org/10.1182/blood-2021-145613

Published: 2021

Journal Articles

AFM28, a Novel Bispecific Innate Cell Engager (ICE ® ), Designed to Selectively Re-Direct NK Cell Lysis to CD123+ Leukemic Cells in Acute Myeloid Leukemia and Myelodysplastic Syndrome

Jana-Julia Götz, Jens Pahl, Nanni Schmitt, Thomas Müller, Torsten Haneke, Izabela Kozlowska, Séverine Sarlang, Stefan Knackmuss, Eike Peters, Uwe Reusch, Thorsten Ross, Daniel Nowak, Wolf-Karsten Hofmann, Christian Merz

Blood (2021) 138 (Supplement 1): 3344.

https://doi.org/10.1182/blood-2021-152463

Published: 2021

Journal Articles

Mesenchymal Stromal Cells (MSCs) from Myelodysplastic Syndromes (MDS) Are Not Clonally Mutated I n Vivo

Johann-Christoph Jann, Maximilian Mossner, Vladimir Riabov, Eva Altrock, Nanni Schmitt, Johanna Flach, Qingyu Xu, Verena Nowak, Julia Obländer, Iris Palme, Nadine Weimer, Alexander Streuer, Ahmed Jawhar, Ali Darwich, Georgia Metzgeroth, Florian Nolte, Wolf-Karsten Hofmann, Daniel Nowak

Blood (2021) 138 (Supplement 1): 1514.

https://doi.org/10.1182/blood-2021-150244

Published: 2021

Journal Articles

Preclinical Assessment of Alvocidib in Combination with 5-Azacytidine in High-Risk Myelodysplastic Syndromes

Vladimir Riabov, Qingyu Xu, Nanni Schmitt, Alexander Streuer, Johann-Christoph Jann, Alina Wein, Eva Altrock, Arwin Mehralivand, Verena Nowak, Nadine Weimer, Julia Obländer, Iris Palme, Mohamad Jawhar, Christel Weiss, Georgia Metzgeroth, Jason M Foulks, Wolf-Karsten Hofmann, Daniel Nowak

Blood (2021) 138 (Supplement 1): 4649.

https://doi.org/10.1182/blood-2021-150778

Published: 2021

Journal Articles

Anti-Leukemic Efficacy of Talazoparib and APE1 Inhibitor III Combined with Decitabine in Myeloid Malignancies

Vanessa Kohl, MSc, Susanne Brendel, MTA, Johanna Flach, PhD, Helga Kleiner, MTA, Christel Weiss, PhD, Wolfgang Seifarth, PhD, Daniel Nowak, MD, Wolf-Karsten Hofmann, MD PhD, Alice Fabarius, PhD, Henning D. Popp

Blood (2019) 134 (Supplement_1): 5056.

https://doi.org/10.1182/blood-2019-122672

Published: 2019

Journal Articles

Comparison of Four Different Humanized Hematopoietic Niche Xenotransplantation Methods to Engraft Myelodysplastic Syndromes (MDS)

Blood (2019) 134 (Supplement_1): 4227.

https://doi.org/10.1182/blood-2019-128075

Published: 2019

Journal Articles

R-Loops-Induced ATR Signaling As a Potential Therapeutic Target in Myelodysplastic Syndrome

Johann-Christoph Jann, Johanna Flach, PhD, Antje Knaflic, Eva Altrock, PhD, Nanni Schmitt, MSc, Alexander Streuer, Justine Danner, Franziska Hofmann, Verena Nowak, Nina Draeger, Julia Obländer, Iris Palme, Patrick Wuchter, MD, Ahmed Jawhar, MD, Georgia Metzgeroth, MD, Florian Nolte, MD, Wolf-Karsten Hofmann, MD PhD, Daniel Nowak, MD

Blood (2019) 134 (Supplement_1): 4218.

https://doi.org/10.1182/blood-2019-126431

Published: 2019

Journal Articles

Placebo Controlled Functional Analysis of Eltrombopag in a Preclinical Xenograft Model of Myelodysplastic Syndromes (MDS)

Nanni Schmitt, MSc, Eva Altrock, PhD, Johann-Christoph Jann, MD, Johanna Flach, PhD, Carla Sens-Albert, PhD, Justine Danner, Stefanie Uhlig, Jovita Pressler, Iris Palme, Verena Nowak, Julia Obländer, Lena Drangmeister, MD, Franziska La Meir, MD, Georgia Metzgeroth, MD, Florian Nolte, MD, Wolf-Karsten Hofmann, Daniel Nowak, MD

Blood (2018) 132 (Supplement 1): 942.

https://doi.org/10.1182/blood-2018-99-116341

Published: 2018

Journal Articles

Genomic CDKN2A/2B deletions in adult Ph + ALL are adverse despite allogeneic stem cell transplantation

Blood (2018) 131 (13): 1464–1475.

https://doi.org/10.1182/blood-2017-07-796862

Published: 2018

Includes: Supplemental data

Journal Articles

Validation of a Molecular Risk Score for Prognosis of Patients with Acute Promyelocytic Leukemia

Anna Hecht, MD, Seraphina Doll, Heidi Schaarschmidt, Daniel Nowak, MD, Verena Nowak, Julia Obländer, Christina Xanthopoulos, Eva Lengfelder, MD, Christoph Röllig, MD, Gerhard Ehninger, MD, Wolf-Karsten Hofmann, MD, Uwe Platzbecker

Blood (2016) 128 (22): 1668.

https://doi.org/10.1182/blood.V128.22.1668.1668

Published: 2016

Journal Articles

RNA Sequencing of Bone Marrow Derived Mesenchymal Stromal Cells (MSCs) of Healthy Young, Healthy Old and Patients with Myelodysplastic Syndrome (MDS) Reveals Transcriptomic Changes upon Aging of the Niche and Onset of MDS

Johann-Christoph Jann, Maximilian Mossner, Florian Nolte, MD, Tobias Boch, MD, Verena Nowak, Iris Palme, Julia Obländer, Jovita Pressler, Christina Xanthopoulos, Henning Röhl, MD, Wolf-Karsten Hofmann, MD, Daniel Nowak, MD

Blood (2016) 128 (22): 4300.

https://doi.org/10.1182/blood.V128.22.4300.4300

Published: 2016

Journal Articles

Safety and Efficacy of the CD95-Ligand Inhibitor APG101 in Transfusion-Dependent Patients with Low Risk MDS: Results from a Phase I Study

Tobias Boch, MD, Thomas Luft, MD PhD, Maximilian Mossner, Johann-Christoph Jann, Daniel Nowak, MD, Christine Folz, Jennifer Klemmer, Susanne Brendel, Harald Fricke, MD, Claudia Kunz, PhD, Wolf-Karsten Hofmann, MD, Florian Nolte, MD

Blood (2016) 128 (22): 228.

https://doi.org/10.1182/blood.V128.22.228.228

Published: 2016

NARROW

Efficacy and Safety of Venetoclax in Combination with Azacitidine for the Treatment of Patients with Treatment-Naive, Higher-Risk Myelodysplastic Syndromes

Instructive Interaction between Myelodysplastic Hematopoiesis and the Bone Marrow Microenvironment at Single Cell Level

Distinct and Targetable Role of Calcium and Calcium Sensing Receptor in Leukaemia

The Novel Bispecific Innate Cell Engager (ICE®) AFM28 Efficiently Directs Allogeneic NK Cells to CD123+ Leukemic Stem- and Progenitor Cells in AML

ASXL1 Mutations Are Associated with a Response to the Combination of Alvocidib and 5-Azacytidine in Higher-Risk Myelodysplastic Syndromes

Inter-Modality Variance of Blast Quantification in Patients with Myelodysplastic Syndrome (MDS) and Its Impact on Risk Stratification and Overall Survival

Inhibition of Lysyl Oxidases Synergizes with 5-Azacytidine to Restore Erythropoiesis in Myeloid Neoplasms

Direct Comparison of NSG and NBSGW Mice for MDS Patient-Derived Xenograft Models

Molecular Responses Are Observed across Mutational Spectrum in Treatment-Naïve Higher-Risk Myelodysplastic Syndrome Patients Treated with Venetoclax Plus Azacitidine

AFM28, a Novel Bispecific Innate Cell Engager (ICE ® ), Designed to Selectively Re-Direct NK Cell Lysis to CD123+ Leukemic Cells in Acute Myeloid Leukemia and Myelodysplastic Syndrome

Mesenchymal Stromal Cells (MSCs) from Myelodysplastic Syndromes (MDS) Are Not Clonally Mutated I n Vivo

Preclinical Assessment of Alvocidib in Combination with 5-Azacytidine in High-Risk Myelodysplastic Syndromes

Anti-Leukemic Efficacy of Talazoparib and APE1 Inhibitor III Combined with Decitabine in Myeloid Malignancies

Comparison of Four Different Humanized Hematopoietic Niche Xenotransplantation Methods to Engraft Myelodysplastic Syndromes (MDS)

R-Loops-Induced ATR Signaling As a Potential Therapeutic Target in Myelodysplastic Syndrome

Placebo Controlled Functional Analysis of Eltrombopag in a Preclinical Xenograft Model of Myelodysplastic Syndromes (MDS)

Genomic CDKN2A/2B deletions in adult Ph + ALL are adverse despite allogeneic stem cell transplantation

Validation of a Molecular Risk Score for Prognosis of Patients with Acute Promyelocytic Leukemia

RNA Sequencing of Bone Marrow Derived Mesenchymal Stromal Cells (MSCs) of Healthy Young, Healthy Old and Patients with Myelodysplastic Syndrome (MDS) Reveals Transcriptomic Changes upon Aging of the Niche and Onset of MDS

Safety and Efficacy of the CD95-Ligand Inhibitor APG101 in Transfusion-Dependent Patients with Low Risk MDS: Results from a Phase I Study

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American Society of Hematology

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