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Journal Articles

Genetic risk stratification and outcomes among treatment-naive patients with AML treated with venetoclax and azacitidine

CME Clinical Trials & Observations
Hartmut Döhner, Keith W. Pratz, Courtney D. DiNardo, Andrew H. Wei, Brian A. Jonas, Vinod A. Pullarkat, Michael J. Thirman, Christian Récher, Andre C. Schuh, Sunil Babu, Xiaotong Li, Grace Ku, Zihuan Liu, Yan Sun, Jalaja Potluri, Monique Dail, Brenda Chyla, Daniel A. Pollyea
Journal: Blood
Blood (2024) 144 (21): 2211–2222.
https://doi.org/10.1182/blood.2024024944
Published: 2024
Includes: Supplemental data
Journal Articles

HIF-1α-Dependent Autophagy Deficiency in Bone Marrow Endothelial Progenitor Cells Contributes to Acute Graft-Versus-Host Disease after Allotransplant

Wenkai Zhang, Xie-Na Cao, Wei Shi, Linghui Xia, Li Li, Chun-Yan Sun, Yu Hu
Journal: Blood
Blood (2023) 142 (Supplement 1): 4794.
https://doi.org/10.1182/blood-2023-184413
Published: 2023
Journal Articles

Long-term follow-up of VIALE-C in patients with untreated AML ineligible for intensive chemotherapy

Clinical Trials & Observations
Andrew H. Wei, Panayiotis Panayiotidis, Pau Montesinos, Kamel Laribi, Vladimir Ivanov, Inho Kim, Jan Novak, Rebecca Champion, Walter Fiedler, Maria Pagoni, Julie Bergeron, Stephen B. Ting, Jing-Zhou Hou, Achilles Anagnostopoulos, Andrew McDonald, Vidhya Murthy, Takahiro Yamauchi, Jianxiang Wang, Qi Jiang, Yan Sun, Brenda Chyla, Wellington Mendes, Courtney D. DiNardo
Journal: Blood
Blood (2022) 140 (25): 2754–2756.
https://doi.org/10.1182/blood.2022016963
Published: 2022
Includes: Supplemental data
Journal Articles

Multi-Omic Single-Cell Sequencing Reveals Genetic and Immunophenotypic Clonal Selection in Patients With FLT3-Mutated AML Treated With Gilteritinib/Venetoclax

Vanessa E. Kennedy, Cheryl Peretz, Paul Lee, Brenda Chyla, Yan Sun, Monique Dail, Jason Hill, Elaine Tran, Andrew Koh, Jessica K. Altman, Naval Daver, Mark J. Levis, James McCloskey, Alexander Perl, Catherine Smith
Journal: Blood
Blood (2022) 140 (Supplement 1): 2244–2246.
https://doi.org/10.1182/blood-2022-160304
Published: 2022
Journal Articles

ELN Risk Stratification Is Not Predictive of Outcomes for Treatment-Naïve Patients with Acute Myeloid Leukemia Treated with Venetoclax and Azacitidine

Hartmut Döhner, Keith W. Pratz, Courtney D. DiNardo, Brian A. Jonas, Vinod A. Pullarkat, Michael J. Thirman, Christian Recher, Andre C. Schuh, Sunil Babu, Monique Dail, Grace Ku, Yan Sun, Jalaja Potluri, Brenda Chyla, Daniel A. Pollyea
Journal: Blood
Blood (2022) 140 (Supplement 1): 1441–1444.
https://doi.org/10.1182/blood-2022-169509
Published: 2022
Journal Articles

The Combination of Navitoclax and Ruxolitinib in JAK Inhibitor-Naïve Patients with Myelofibrosis Mediates Responses Suggestive of Disease Modification

Francesco Passamonti, James M. Foran, Anand Tandra, Valerio De Stefano, Maria Laura Fox, Ahmad H. Mattour, Mary Frances McMullin, Andrew Charles Perkins, Gabriela Rodríguez-Macias, Hassan Sibai, Qin Qin, Yan Sun, Jalaja Potluri, Jason Harb, Jonathan How
Journal: Blood
Blood (2022) 140 (Supplement 1): 583–585.
https://doi.org/10.1182/blood-2022-157949
Published: 2022
Journal Articles

Overall Survival By Best Overall Response with Tabelecleucel in Patients with Epstein-Barr Virus-Driven Post-Transplant Lymphoproliferative Disease Following Solid Organ or Allogeneic Hematopoietic Cell Transplant

Susan Prockop, Laurence Gamelin, Rajani Dinavahi, Yan Sun, Weizhi Zhao, Faith Galderisi, Aditi Mehta
Journal: Blood
Blood (2021) 138 (Supplement 1): 887.
https://doi.org/10.1182/blood-2021-147226
Published: 2021
Journal Articles

Molecular Responses Are Observed across Mutational Spectrum in Treatment-Naïve Higher-Risk Myelodysplastic Syndrome Patients Treated with Venetoclax Plus Azacitidine

Jacqueline S. Garcia, Andrew H. Wei, Meagan A. Jacoby, Chun Yew Fong, Uma Borate, Maria R. Baer, Ilona Cunningham, Olatoyosi Odenike, Joseph G. Jurcic, Daniel Nowak, Pierre Peterlin, Uwe Platzbecker, Diana Dunshee, Ying Zhou, David Hoffman, Yan Sun, Relja Popovic, Barrett Ainsworth, Kiran Naqvi, Steve Kye, Leah Hogdal, Guillermo Garcia-Manero
Journal: Blood
Blood (2021) 138 (Supplement 1): 241.
https://doi.org/10.1182/blood-2021-145613
Published: 2021
Journal Articles

Outcomes in Patients with Poor-Risk Cytogenetics with or without TP53 Mutations Treated with Venetoclax Combined with Hypomethylating Agents

Daniel A. Pollyea, Keith W. Pratz, Andrew H. Wei, Vinod A. Pullarkat, Brian A. Jonas, Christian Recher, Sunil Babu, Andre C. Schuh, Monique Dail, Yan Sun, Jalaja Potluri, Brenda Chyla, Courtney D. DiNardo
Journal: Blood
Blood (2021) 138 (Supplement 1): 224.
https://doi.org/10.1182/blood-2021-145639
Published: 2021
Journal Articles

Human Cytomegalovirus Selectively Suppresses the Megakaryo/Thrombopoiesis of PDGFR + and αvβ3 + Megakaryocytes Via the TPO/c-Mpl Pathway after Allo-HSCT

Feng-qi Liu, Fei-er Feng, Gao-chao Zhang, Yan Su, Xue-yan Sun, Qiu-sha Huang, Qi Chen, Xiao Liu, Yun He, Xiao-lu Zhu, Hai-xia Fu, Kai-yan Liu, Xiao-hui Zhang
Journal: Blood
Blood (2020) 136 (Supplement 1): 25.
https://doi.org/10.1182/blood-2020-137115
Published: 2020
Journal Articles

Biomarker Modulation By Mivebresib (ABBV-075) +/- Venetoclax in Relapsed/Refractory Acute Myeloid Leukemia

Gautam M. Borthakur, MD, Olatoyosi Odenike, MD, Ibrahim Aldoss, MD, David A. Rizzieri, MD, Thomas Prebet, MD PhD, Dimple A. Modi, PhD, Rujuta Joshi, Beibei Hu, Yan Sun, PhD, Johannes E. Wolff, MD, Brian A Jonas, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 539.
https://doi.org/10.1182/blood-2019-126854
Published: 2019
Journal Articles

Response to Venetoclax in Combination with Low Intensity Therapy (LDAC or HMA) in Untreated Patients with Acute Myeloid Leukemia Patients with IDH, FLT3 and Other Mutations and Correlations with BCL2 Family Expression

Brenda J Chyla, PhD, Jason Harb, PhD, Christine Mantis, PhD, Jacob J Riehm, PhD, Jeremy A. Ross, PhD, Yan Sun, PhD, Xin Huang, PhD MD, Qi Jiang, PhD, Monique Dail, PhD, Franklin V. Peale, Jr., MD PhD, Jalaja Potluri, MD, John Hayslip
Journal: Blood
Blood (2019) 134 (Supplement_1): 546.
https://doi.org/10.1182/blood-2019-128373
Published: 2019
Journal Articles

T(11;14) and High BCL2 Expression Are Predictive Biomarkers of Response to Venetoclax in Combination with Bortezomib and Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma: Biomarker Analyses from the Phase 3 Bellini Study

Simon Harrison, MBBS, MRCP, FRCPath, FRACP, PhD, Michele Cavo, Javier De La Rubia, Rakesh Popat, Cristina Gasparetto, MD, Vania T.M. Hungria, MD PhD, Hans Salwender, Kenshi Suzuki, MD PhD, Inho Kim, MD PhD, Philippe Moreau, MD, Andrew Spencer, MBBS, FRACP, FRCPA, DM, Michael E O'Dwyer, MD, Mamta Garg, MD FRCP, FRCPath, Elizabeth A Punnoose, PhD, Muhammad Jalaluddin, PhD, Jia Jia, PhD MBA, Xiaoqing Yang, PhD, Yan Sun, PhD, James E. Ward, MD, Paulo C. Maciag, MD PhD, Jeremy A. Ross, PhD, Shaji K. Kumar, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 142.
https://doi.org/10.1182/blood-2019-126094
Published: 2019
Journal Articles

Long-Term Outcomes of Subjects with Epstein-Barr Virus-Driven Post-Transplant Lymphoproliferative Disorder (EBV + PTLD) Following Solid Organ (SOT) or Allogeneic Hematopoietic Cell Transplants (HCT) Treated with Tabelecleucel on an Expanded Access Program

Susan Prockop, MD, Ran Reshef, MDMSc, Donald E. Tsai, MD PhD, Nancy Bunin, MD, Rolla Abu-Arja, MD, Kris Michael Mahadeo, MD, Wen-Kai Weng, MD PhD, Koen Van Besien, MD PhD, David Loeb, MD PhD, Sunita Dwivedy Nasta, MD, Eneida R. Nemecek, MDMBA,MSc, Minoti Hiremath, MBBS, PhD, Susan Yue, MD, Yan Sun, PhD, Willis Navarro, MD, Sarah Nikiforow, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4071.
https://doi.org/10.1182/blood-2019-124904
Published: 2019
Journal Articles

A Retrospective Analysis of Outcomes of Diffuse Large B Cell Lymphoma (DLBCL) in the Elder Patients in China

Peng Liu, Ying Han, Jianliang Yang, Xiaohui He, Changgong Zhang, Shengyu Zhou, Yan Qin, Liqiang Zhou, Song Yongwen, Ming-Zhe Han, MD, Yan Sun, Yuankai Shi, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5410.
https://doi.org/10.1182/blood-2018-99-116641
Published: 2018
Journal Articles

A Prognostic Nomogram and Survival Analysis in Relapsed or Refractory Diffuse Large B-Cell Lymphoma Patients

Shiyu Jiang, Yan Qin, Peng Liu, Jiangliang Yang, Sheng Yang, Xiaohui He, Shengyu Zhou, Lin Gui, Changgong Zhang, Liqiang Zhou, Ming-Zhe Han, Yan Sun, Yuankai Shi, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2994.
https://doi.org/10.1182/blood-2018-99-116442
Published: 2018
Journal Articles

CircPVT1 Inhibit Apoptosis and Enhance Drug Resistance in Multiple Myeloma

Xiao-Yue Wan, MD, Zhang-Bo Chu, MDPhD, Yu Hu, MD PhD, Chun-Yan Sun, MD PhD, Jing Zou, PhD MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3085.
https://doi.org/10.1182/blood.V130.Suppl_1.3085.3085
Published: 2017
Journal Articles

MicroRNA-486 regulates normal erythropoiesis and enhances growth and modulates drug response in CML progenitors

Li-Sheng Wang, Ling Li, Liang Li, Su Chu, Keh-Dong Shiang, Min Li, Hui-Yan Sun, Jun Xu, Feng-Jun Xiao, Guihua Sun, John J. Rossi, YinWei Ho, Ravi Bhatia
Journal: Blood
Blood (2015) 125 (8): 1302–1313.
https://doi.org/10.1182/blood-2014-06-581926
Published: 2015
Includes: Supplemental data
Journal Articles

Brain-Derived Neurotrophic Factor Enhances Osteoclastogenesis in Multiple Myeloma via Upregulation of RANKL/OPG Ratio Both in Vitro and in a Murine Model of Myeloma Bone Disease

Li-Sha Ai, Chun-Yan Sun, Tao Guo, Ya-Dan Wang, Lu Zhang, You Qin, Lei Chen, Han Yan, Wei Zeng, Jun Fang, Yu Hu
Journal: Blood
Blood (2012) 120 (21): 568.
https://doi.org/10.1182/blood.V120.21.568.568
Published: 2012
Journal Articles

Down-Regulation of Homeobox Gene Ventx Promotes Expansion of Human Bone Marrow Hematopoietic Stem Cells (HSC)

Hong (Jenny) Gao, MD, Ph.D., Xiaoming Wu, Ph.D., Yan Sun, PH.D.&M.D., Jiayun Lu, MD, PhD, Leslie E Silberstein, MD, Zhenglun (Jerry) Zhu, MD, Ph.D.
Journal: Blood
Blood (2011) 118 (21): 1272.
https://doi.org/10.1182/blood.V118.21.1272.1272
Published: 2011