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Journal Articles

Hijacking of the Fibrinolytic System By B-Cell Acute Lymphoblastic Leukaemia and Its Therapeutic Targeting

Valentina Minciacchi, Christina Karantanou, Costanza Zanetti, Rahul Kumar, Theresa Krack, Nathalie Thomasberger, Pablo Llavona, Sylvia Hartmann, Veronique Maguer-Satta, Sylvain Lefort, Mateusz Putyrski, Andreas Ernst, Eshwar Meduri, Brian Huntly, Wolfram Ruf, Daniela S. Krause
Journal: Blood
Blood (2023) 142 (Supplement 1): 2781.
https://doi.org/10.1182/blood-2023-178811
Published: 2023
Journal Articles

Distinct and Targetable Role of Calcium and Calcium Sensing Receptor in Leukaemia

Raquel Pereira, Rahul Kumar, Alessia Cais, Lara Paulini, Alisa Kahler, Jimena Bravo, Valentina R. Minciacchi, Eric Kowarz, Costanza Zanetti, Parimala Sonika Godavarthy, Fabian Hoeller, Pablo Llavona, Tabea Stark, Georg Tascher, Daniel Nowak, Eshwar Meduri, Brian Huntly, Christian Münch, Francesco Pampaloni, Rolf Marschalek, Daniela S. Krause
Journal: Blood
Blood (2023) 142 (Supplement 1): 5709.
https://doi.org/10.1182/blood-2023-177990
Published: 2023
Journal Articles

HOXA9 Nucleates a Repressive Chromatin Complex with Nuclear Matrix-Associated Protein- Safb to Maintain Acute Myeloid Leukemia

Shuchi Agrawal Singh, Jaana Bagri, George Giotopoulos, Eshwar Meduri, Shubha Anad, Sarah J. Horton, Daniel Sasca, Haiyang Yun, Anthony Whetton, Brian James Patrick Huntly
Journal: Blood
Blood (2022) 140 (Supplement 1): 720–721.
https://doi.org/10.1182/blood-2022-156341
Published: 2022
Journal Articles

Genetic Vulnerabilities of DNMT3A R882H in Myeloid Malignancies

Malgorzata Gozdecka, PhD, Monika Dudek, MSc, Konstantinos Tzelepis, Aristi Damaskou, MSc, Vijay Baskar, PhD, Penny Wright, Graham Duddy, Eshwar Meduri, PhD, Milena Mazan, PhD, Kosuke Yusa, PhD, Brian J. P. Huntly, PhD MRCP, MB, FRCPath, George S. Vassiliou, FRCPath, MRCP, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 111.
https://doi.org/10.1182/blood-2019-126505
Published: 2019
Journal Articles

Mutational Synergy Coordinately Remodels Chromatin Accessibility, Enhancer Landscape and 3-Dimensional DNA Topology to Alter Gene Expression during Leukemia Induction

Haiyang Yun, PhD, Shabana Vohra, PhD, Annalisa Mupo, PhD, George Giotopoulos, PhD, Daniel Sasca, MD, Sarah J. Horton, PhD, Shuchi Agrawal-Singh, PhD, Eshwar Meduri, PhD, Faisal Basheer, MBBChir, MA, PhD, Ludovica Marando, Malgorzata Gozdecka, PhD, Oliver M. Dovey, PhD, Xiaonan Wang, PhD, Paolo Gallipoli, PhD, Cameron Osborne, PhD, George S. Vassiliou, FRCPath, MRCP, PhD, Brian J. P. Huntly, PhD MRCP, MB, FRCPath
Journal: Blood
Blood (2019) 134 (Supplement_1): 278.
https://doi.org/10.1182/blood-2019-122413
Published: 2019
Journal Articles

Contrasting Stage Dependent Requirements for the Histone Methyltransferase EZH2 during the Evolution of Acute Myeloid Leukemia

Faisal Basheer, MBBChir, MA, George Giotopoulos, PhD, Eshwar Meduri, PhD, Haiyang Yun, PhD, Milena Mazan, PhD, Olivia Sheppard, Daniel Sasca, MD, Malgorzata Gozdecka, PhD, George S. Vassiliou, MD PhD, Brian J.P Huntly
Journal: Blood
Blood (2017) 130 (Supplement 1): 1215.
https://doi.org/10.1182/blood.V130.Suppl_1.1215.1215
Published: 2017
Journal Articles

Functional and Molecular Consequences of the Dnmt3aR882H Mutation in Acute Myeloid Leukaemia

Malgorzata Gozdecka, PhD, Milena M. Mazan, PhD, Vivek Iyer, Anna Farne, Eshwar Meduri, Ruben Bautista, Nicolas Walker, Anne C Ferguson-Smith, PhD, George S. Vassiliou, MD PhD, Brian J.P Huntly, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2424.
https://doi.org/10.1182/blood.V126.23.2424.2424
Published: 2015
Journal Articles

Modelling Cellular and Molecular Progression Of CML In The Mouse

George Giotopoulos, Louise Van Der Weyden, Hikari Osaki, Wai-In Chan, Alistair Rust, Eshwar Meduri, Steffen Koschmieder, Daniel Tenen, George Vassiliou, David Adams, Brian Huntly
Journal: Blood
Blood (2013) 122 (21): 2706.
https://doi.org/10.1182/blood.V122.21.2706.2706
Published: 2013