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Journal Articles

Germ line DDX41 mutations define a unique subtype of myeloid neoplasms

Hideki Makishima, Ryunosuke Saiki, Yasuhito Nannya, Sophia Korotev, Carmelo Gurnari, June Takeda, Yukihide Momozawa, Steve Best, Pramila Krishnamurthy, Tetsuichi Yoshizato, Yoshiko Atsuta, Yusuke Shiozawa, Yuka Iijima-Yamashita, Kenichi Yoshida, Yuichi Shiraishi, Yasunobu Nagata, Nobuyuki Kakiuchi, Makoto Onizuka, Kenichi Chiba, Hiroko Tanaka, Ayana Kon, Yotaro Ochi, Masahiro M. Nakagawa, Rurika Okuda, Takuto Mori, Akinori Yoda, Hidehiro Itonaga, Yasushi Miyazaki, Masashi Sanada, Takayuki Ishikawa, Shigeru Chiba, Hisashi Tsurumi, Senji Kasahara, Carsten Müller-Tidow, Akifumi Takaori-Kondo, Kazuma Ohyashiki, Toru Kiguchi, Fumihiko Matsuda, Joop H. Jansen, Chantana Polprasert, Piers Blombery, Yoichiro Kamatani, Satoru Miyano, Luca Malcovati, Torsten Haferlach, Michiaki Kubo, Mario Cazzola, Austin G. Kulasekararaj, Lucy A. Godley, Jaroslaw P. Maciejewski, Seishi Ogawa

Blood (2023) 141 (5): 534–549.

https://doi.org/10.1182/blood.2022018221

Published: 2023

Includes: Supplemental data

Journal Articles

Cooperative Effects of SRSF2 and STAG2 mutations on Development of Myelodysplastic Syndrome and Its Related Disorders

Blood (2022) 140 (Supplement 1): 4022–4023.

https://doi.org/10.1182/blood-2022-158748

Published: 2022

Journal Articles

Germline Risks and Clinical Impacts of DDX41 Mutations in Myeloid Malignancies

Hideki Makishima, Ryunosuke Saiki, Yasuhito Nannya, Sophia C. Korotev, Carmelo Gurnari, June Takeda, Yukihide Momozawa, Steve Best, Pramila Krishnamurthy, Tetsuichi Yoshizato, Yoshiko Atsuta, Yusuke Shiozawa, Yuka Iijima-Yamashita, Kenichi Yoshida, Yuichi Shiraishi, Yasunobu Nagata, Nobuyuki Kakiuchi, Makoto Onizuka, Kenichi Chiba, Hiroko Tanaka, Ayana Kon, Yotaro Ochi, Masahiro Marshall Nakagawa, Rurika Okuda, Takuto Mori, Akinori Yoda, Hidehiro Itonaga, Yasushi Miyazaki, Masashi Sanada, Takayuki Ishikawa, Shigeru Chiba, Hisashi Tsurumi, Senji Kasahara, Carsten Müller-Tidow, Akifumi Takaori-Kondo, Kazuma Ohyashiki, Toru Kiguchi, Fumihiko Matsuda, Joop H. Jansen, Chantana Polprasert, Piers Blombery, Yoichiro Kamatani, Satoru Miyano, Luca Malcovati, Torsten Haferlach, Michiaki Kubo, Mario Cazzola, Austin Kulasekararaj, Lucy A. Godley, Jaroslaw P. Maciejewski, Seishi Ogawa

Blood (2022) 140 (Supplement 1): 208–210.

https://doi.org/10.1182/blood-2022-158851

Published: 2022

Journal Articles

Machine learning integrates genomic signatures for subclassification beyond primary and secondary acute myeloid leukemia

Blood (2021) 138 (19): 1885–1895.

https://doi.org/10.1182/blood.2020010603

Published: 2021

Includes: Supplemental data

Journal Articles

Epigenetic Enzyme Mutations in Myeloid Malignancies Are Selected By Chromatin-Remodeling Requirements That Vary By Lineage- and Maturation-Stage

Sunisa Kongkiatkamon, Xiaorong Gu, Kwok Peng Ng, Simona Pagliuca, Vera Adema, Wencke Walter, Yasunobu Nagata, Cassandra M Kerr, Cassandra M Kerr, Manja Meggendorfer, Hassan Awada, Stephan Hutter, Carmelo Gurnari, Claudia Haferlach, Babal K. Jha, Valeria Visconte, Torsten Haferlach, Jaroslaw P. Maciejewski, Yogenthiran Saunthararajah

Blood (2021) 138 (Supplement 1): 1148.

https://doi.org/10.1182/blood-2021-153618

Published: 2021

Journal Articles

Der(1;7)(q10;p10) Presents with a Unique Genetic Profile and Frequent ETNK1 Mutations in Myeloid Neoplasms

Blood (2021) 138 (Supplement 1): 1513.

https://doi.org/10.1182/blood-2021-149556

Published: 2021

Journal Articles

EPOR/JAK/STAT Signaling Pathway As Therapeutic Target of Acute Erythroid Leukemia

Blood (2021) 138 (Supplement 1): 610.

https://doi.org/10.1182/blood-2021-152800

Published: 2021

Journal Articles

Germline MPO Variants Predispose to Myeloid Neoplasia: Potential Mechanisms Suggested By In Vivo and in Vitro Studies

Blood (2021) 138 (Supplement 1): 3662.

https://doi.org/10.1182/blood-2021-149598

Published: 2021

Journal Articles

Machine learning demonstrates that somatic mutations imprint invariant morphologic features in myelodysplastic syndromes

Yasunobu Nagata, Ran Zhao, Hassan Awada, Cassandra M. Kerr, Inom Mirzaev, Sunisa Kongkiatkamon, Aziz Nazha, Hideki Makishima, Tomas Radivoyevitch, Jacob G. Scott, Mikkael A. Sekeres, Brian P. Hobbs, Jaroslaw P. Maciejewski

Blood (2020) 136 (20): 2249–2262.

https://doi.org/10.1182/blood.2020005488

Published: 2020

Includes: Supplemental data

Journal Articles

Double Genetic Hits and Subclonal Mosaicism in the Ras Signaling Pathway in Myeloid Neoplasia

Sunisa Kongkiatkamon, MD, Yasunobu Nagata, MD PhD, Vera Adema, PhD, Hassan Awada, MD, Misam Zawit, MD, Laila Terkawi, Simona Pagliuca, MD, Carmelo Gurnari, MD, Cassandra M Kerr, MS, Mikkael A. Sekeres, MD MS, Hetty E. Carraway, MD MBA, Yogenthiran Saunthararajah, MD, Bhumika J. Patel, MD, Jaroslaw P. Maciejewski, MD PhD, Valeria Visconte, PhD

Blood (2020) 136 (Supplement 1): 34–35.

https://doi.org/10.1182/blood-2020-143210

Published: 2020

Journal Articles

Genotype-Phenotype Relationships and Therapeutic Targets in Acute Erythroid Leukemia

June Takeda, MD, Kenichi Yoshida, MDPhD, Akinori Yoda, PhD, Lee-Yung Shih, MD, Yasuhito Nannya, MD PhD, Yotaro Ochi, MD, Ayana Kon, MD PhD, Kenichi Chiba, Yuichi Shiraishi, PhD, Yusuke Shiozawa, MD PhD, Tetsuichi Yoshizato, MD PhD, Cassandra M Kerr, MS, Yasunobu Nagata, MD PhD, Toshiyuki Kitano, MD PhD, Akira Hangaishi, MD PhD, Ken Ishiyama, MD PhD, Hisashi Tsurumi, MD PhD, Yasushi Miyazaki, MD PhD, Nobuhiro Hiramoto, MD, Takayuki Ishikawa, MD PhD, Masahiro Marshall Nakagawa, MDPhD, Akifumi Takaori-Kondo, MD PhD, Shigeru Chiba, MD PhD, Hideyuki Nakazawa, MD PhD, Ming-Chung Kuo, MD, Keisuke Kataoka, MD PhD, Ryunosuke Saiki, MD, Hiroko Tanaka, Kensuke Usuki, MD PhD, Shuichi Miyawaki, MD PhD, Satoru Miyano, PhD, Jaroslaw P. Maciejewski, MD PhD, Arnold Ganser, Michael Heuser, Prof., MD, Felicitas Thol, Hideki Makishima, MD PhD, Seishi Ogawa, MD PhD

Blood (2020) 136 (Supplement 1): 17–18.

https://doi.org/10.1182/blood-2020-141750

Published: 2020

Journal Articles

Rare Germline Alterations of Myeloperoxidase Predispose to Myeloid Neoplasms and Are Associated with Increased Circulating Burden of Microbial DNA

Sunisa Kongkiatkamon, MD, Samuel Li, BA, Tatiana Dombrovski, Laila Terkawi, Cassandra M Kerr, MS, Vera Adema, PhD, Yasunobu Nagata, MD PhD, Wencke Walter, PhD, Hassan Awada, MD, Bartlomiej Przychodzen, Stephan Hutter, PhD, Carmelo Gurnari, MD, Simona Pagliuca, MD, Manja Meggendorfer, PhD, Claudia Haferlach, MD, Valeria Visconte, PhD, Torsten Haferlach, MD, Jaroslaw P. Maciejewski, MD PhD, Thomas LaFramboise, PhD

Blood (2020) 136 (Supplement 1): 2–3.

https://doi.org/10.1182/blood-2020-139972

Published: 2020

Journal Articles

The Application of Machine Learning to Improve the Subclassification and Prognostication of Acute Myeloid Leukemia

Blood (2020) 136 (Supplement 1): 28.

https://doi.org/10.1182/blood-2020-139013

Published: 2020

Journal Articles

Clinical Impacts of Germline DDX41 Mutations on Myeloid Neoplasms

Hideki Makishima, MD PhD, Yasuhito Nannya, MD PhD, June Takeda, MD, Yukihide Momozawa, DVM,PhD, Ryunosuke Saiki, MD, Tetsuichi Yoshizato, MD PhD, Yoshiko Atsuta, MD PhD, Yuka Iijima-Yamashita, Kenichi Yoshida, MD PhD, Yuichi Shiraishi, PhD, Yasunobu Nagata, MD PhD, Yusuke Shiozawa, MD PhD, Makoto Onizuka, MD PhD, Kenichi Chiba, Hiroko Tanaka, Nobuyuki Kakiuchi, MD, Yotaro Ochi, MD, Hiroo Ueno, MD PhD, Hidehiro Itonaga, MD PhD, Yoshinobu Kanda, MD PhD, Masashi Sanada, MD, Ayana Kon, MD PhD, Yasushi Miyazaki, MD PhD, Keizo Horibe, MD PhD, Maria Creignou, Magnus Tobiasson, MD, Hisashi Tsurumi, MD PhD, Senji Kasahara, MD PhD, Chantana Polprasert, MD, Eva Hellstrom Lindberg, MD PhD, Akifumi Kondo Takaori, MD PhD, Toru Kiguchi, MD PhD, Mario Cazzola, MD, Fumihiko Matsuda, MD PhD, Kazuma Ohyashiki, MD PhD, Jaroslaw P. Maciejewski, MD PhD, Torsten Haferlach, MD, Yoichiro Kamatani, MDPhD, Michiaki Kubo, MDPhD, Satoru Miyano, PhD, Seishi Ogawa, MD PhD

Blood (2020) 136 (Supplement 1): 38–40.

https://doi.org/10.1182/blood-2020-140174

Published: 2020

Journal Articles

Can Monosomy 7 be Targeted By Next Generation Cereblon-Modulating Agents?

Blood (2019) 134 (Supplement_1): 1270.

https://doi.org/10.1182/blood-2019-128967

Published: 2019

Journal Articles

TET Dioxygenase Inhibition As a Therapeutic Strategy in TET2 Mutant Myeloid Neoplasia

Yihong Guan, PhD, Anand D. Tiwari, PhD, James G Phillips, PhD, Metis Hasipek, PhD, Dale Grabowski, BS, Cassandra M Kerr, MS, Vera Adema, PhD, Yasunobu Nagata, MD PhD, Valeria Visconte, PhD, Tomas Radivoyevitch, PhD, Daniel Lindner, MD PhD, Manja Meggendorfer, PhD, Mohamed Abazeed, Mikkael A. Sekeres, MD MS, Torsten Haferlach, MD, Jaroslaw P. Maciejewski, MD PhD, Babal K. Jha, PhD

Blood (2019) 134 (Supplement_1): 880.

https://doi.org/10.1182/blood-2019-131920

Published: 2019

Journal Articles

Novel Molecular Pathogenesis and Therapeutic Target in Acute Erythroid Leukemia

Blood (2019) 134 (Supplement_1): 914.

https://doi.org/10.1182/blood-2019-129940

Published: 2019

Journal Articles

PPM1D and DNMT3A Mutations in Myelodysplasia and Clonal Hematopoiesis

Blood (2019) 134 (Supplement_1): 1709.

https://doi.org/10.1182/blood-2019-122032

Published: 2019

Journal Articles

How Morphologic Features Are Shaped By Underlying Somatic Genotype in MDS

Yasunobu Nagata, MD PhD, Ran Zhao, Hassan Awada, Cassandra M Kerr, MS, Abhinav Goyal, Inom Mirzaev, Sunisa Kongkiatkamon, Aziz Nazha, MD, Tomas Radivoyevitch, PhD, Jacob Scott, MD, Mikkael A. Sekeres, MD MS, Brian P. Hobbs, PhD, Jaroslaw P. Maciejewski, MD PhD

Blood (2019) 134 (Supplement_1): 1716.

https://doi.org/10.1182/blood-2019-127285

Published: 2019

Journal Articles

A Personalized Prediction Model to Risk Stratify Patients with Acute Myeloid Leukemia (AML) Using Artificial Intelligence

Blood (2019) 134 (Supplement_1): 2091.

https://doi.org/10.1182/blood-2019-128066

Published: 2019

NARROW

Germ line DDX41 mutations define a unique subtype of myeloid neoplasms

Cooperative Effects of SRSF2 and STAG2 mutations on Development of Myelodysplastic Syndrome and Its Related Disorders

Germline Risks and Clinical Impacts of DDX41 Mutations in Myeloid Malignancies

Machine learning integrates genomic signatures for subclassification beyond primary and secondary acute myeloid leukemia

Epigenetic Enzyme Mutations in Myeloid Malignancies Are Selected By Chromatin-Remodeling Requirements That Vary By Lineage- and Maturation-Stage

Der(1;7)(q10;p10) Presents with a Unique Genetic Profile and Frequent ETNK1 Mutations in Myeloid Neoplasms

EPOR/JAK/STAT Signaling Pathway As Therapeutic Target of Acute Erythroid Leukemia

Germline MPO Variants Predispose to Myeloid Neoplasia: Potential Mechanisms Suggested By In Vivo and in Vitro Studies

Machine learning demonstrates that somatic mutations imprint invariant morphologic features in myelodysplastic syndromes

Double Genetic Hits and Subclonal Mosaicism in the Ras Signaling Pathway in Myeloid Neoplasia

Genotype-Phenotype Relationships and Therapeutic Targets in Acute Erythroid Leukemia

Rare Germline Alterations of Myeloperoxidase Predispose to Myeloid Neoplasms and Are Associated with Increased Circulating Burden of Microbial DNA

The Application of Machine Learning to Improve the Subclassification and Prognostication of Acute Myeloid Leukemia

Clinical Impacts of Germline DDX41 Mutations on Myeloid Neoplasms

Can Monosomy 7 be Targeted By Next Generation Cereblon-Modulating Agents?

TET Dioxygenase Inhibition As a Therapeutic Strategy in TET2 Mutant Myeloid Neoplasia

Novel Molecular Pathogenesis and Therapeutic Target in Acute Erythroid Leukemia

PPM1D and DNMT3A Mutations in Myelodysplasia and Clonal Hematopoiesis

How Morphologic Features Are Shaped By Underlying Somatic Genotype in MDS

A Personalized Prediction Model to Risk Stratify Patients with Acute Myeloid Leukemia (AML) Using Artificial Intelligence

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American Society of Hematology

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American Society of Hematology

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