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Journal Articles

Rare Germline Alterations of Myeloperoxidase Predispose to Myeloid Neoplasms and Are Associated with Increased Circulating Burden of Microbial DNA

Sunisa Kongkiatkamon, MD, Samuel Li, BA, Tatiana Dombrovski, Laila Terkawi, Cassandra M Kerr, MS, Vera Adema, PhD, Yasunobu Nagata, MD PhD, Wencke Walter, PhD, Hassan Awada, MD, Bartlomiej Przychodzen, Stephan Hutter, PhD, Carmelo Gurnari, MD, Simona Pagliuca, MD, Manja Meggendorfer, PhD, Claudia Haferlach, MD, Valeria Visconte, PhD, Torsten Haferlach, MD, Jaroslaw P. Maciejewski, MD PhD, Thomas LaFramboise, PhD

Blood (2020) 136 (Supplement 1): 2–3.

https://doi.org/10.1182/blood-2020-139972

Published: 2020

Journal Articles

Pharmacologic Normalization of Altered Transcriptome of SF3B1 Mutant Myeloid Neoplasia

Blood (2019) 134 (Supplement_1): 564.

https://doi.org/10.1182/blood-2019-129189

Published: 2019

Journal Articles

The Biological Inferences from the Ranking of SF3B1 Mutations in the Clonal Hierarchy of Myeloid Neoplasia

Hassan Awada, Jibran Durrani, Ashwin Kishtagari, MBBS, Vera Adema, PhD, Cassandra M Kerr, MS, Sunisa Kongkiatkamon, Bartlomiej Przychodzen, Jack Khouri, MD, Heesun J. Rogers, MD PhD, Manja Meggendorfer, PhD, Anjali S. Advani, MD, Aziz Nazha, MD, Torsten Haferlach, MD, Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Jaroslaw P. Maciejewski, MD PhD, Valeria Visconte, PhD

Blood (2019) 134 (Supplement_1): 5411.

https://doi.org/10.1182/blood-2019-128965

Published: 2019

Journal Articles

Molecular Dissection of Del(5q): Distinction between Primary and Secondary Del(5q) and Pathogenetic Implications

Vera Adema, PhD, Laura Palomo, Cassandra M Kerr, MS, Wencke Walter, PhD, Bartlomiej Przychodzen, Stephan Hutter, PhD, Thomas Laframboise, PhD, María Díez-Campelo, MD PhD, Mar Mallo, PhD, Aziz Nazha, MD, Blanca Xicoy, MD MSc, Manja Meggendorfer, PhD, Hetty E. Carraway, MD MBA, Claudia Haferlach, MD, Mikkael A. Sekeres, MD MS, Valeria Visconte, PhD, Torsten Haferlach, MD, Francesc Sole, PhD, Jaroslaw P. Maciejewski, MD PhD

Blood (2019) 134 (Supplement_1): 4221.

https://doi.org/10.1182/blood-2019-129292

Published: 2019

Journal Articles

Therapeutic Applications of a Unique Calcium Channel Blocker to Target SF3B1 MDS

Sunisa Kongkiatkamon, Anand Tiwari, Vera Adema, PhD, Cassandra M Kerr, MS, Bartlomiej Przychodzen, Hassan Awada, Jibran Durrani, Yvonne Parker, Drew Adams, Yuriy Fedorov, Hetty E. Carraway, MD MBA, Chao-Yie Yang, Mikkael A. Sekeres, MD MS, Daniel J. Lindner, James G Phillips, PhD, Jaroslaw P. Maciejewski, MD PhD, Valeria Visconte, PhD

Blood (2019) 134 (Supplement_1): 881.

https://doi.org/10.1182/blood-2019-128671

Published: 2019

Journal Articles

Angioimmunoblastic T-Cell Lymphoma: Molecular Characterization of Clonal T and B-Cells and a Patient Derived Xenograft Model of Coexisting T and B-Cell Proliferations

Xiaoxian Zhao, PhD, Bartlomiej Przychodzen, Juraj Bodo, PhD, Lisa Durkin, Daniel Lindner, MD PhD, Neetha Parameswaran, PhD, Michael Clemente, MS, Sarah L. Ondrejka, DO, Jaroslaw P. Maciejewski, MD PhD, Deepa Jagadeesh, MDMPH, Eric D. Hsi, MD

Blood (2019) 134 (Supplement_1): 1572.

https://doi.org/10.1182/blood-2019-129131

Published: 2019

Journal Articles

Integrated Analysis of Copy-Number Alterations and Gene Mutations in 2,000 Patients with Myeloid Neoplasms

Ryunosuke Saiki, Yusuke Shiozawa, MD PhD, Tetsuichi Yoshizato, MD PhD, Yasuhito Nannya, MD PhD, June Takeda, MD, Kenichi Yoshida, MD PhD, Yuichi Shiraishi, PhD, Hiroko Tanaka, BA, Kenichi Chiba, PhD, Yoshiko Atsuta, MD PhD, Makoto Onizuka, MD PhD, Hidehiro Itonaga, MD PhD, Masashi Sanada, MD, Yoshinobu Kanda, MD PhD, Bartlomiej Przychodzen, Mikkael A. Sekeres, MD MS, Kathryn Guinta, Yogenthiran Saunthararajah, MD, Lee-Yung Shih, MD, Shuichi Miyawaki, MD PhD, Tsuyoshi Nakamaki, MD PhD, Masataka Taguchi, Shigeo Fuji, MD PhD, Nana Sasaki, MD, Nobuhiko Uoshima, MD PhD, Yasunori Ueda, MD PhD, Yasushi Miyazaki, MD PhD, Kensuke Usuki, MD PhD, Kazunori Imada, MD PhD, Akifumi Takaori-Kondo, MD PhD, Shigeru Chiba, MD PhD, Senji Kasahara, MD PhD, Toru Kiguchi, MD PhD, Hisashi Tsurumi, MD PhD, Luca Malcovati, MD, Mario Cazzola, MD, Takayuki Ishikawa, MD PhD, Satoru Miyano, PhD, Jaroslaw P. Maciejewski, MD PhD, Hideki Makishima, MD PhD, Seishi Ogawa, MD PhD

Blood (2019) 134 (Supplement_1): 4216.

https://doi.org/10.1182/blood-2019-132174

Published: 2019

Journal Articles

Molecular Spectrum of CSF3R variants Correlate with Specific Myeloid Malignancies and Secondary Mutations

Vera Adema, PhD, Cassandra M. Hirsch, Bartlomiej Przychodzen, Yasunobu Nagata, Tomas Radivoyevitch, Thomas Laframboise, PhD, Amy C Graham, BS, MS, Louis Williams, MD MBA, Hassan Awada, MD, Aziz Nazha, Hetty E. Carraway, MD MBA, Valeria Santini, Hrishikesh M Mehta, PhD, Francesc Sole, PhD, Mikkael A. Sekeres, MD MS, Valeria Visconte, PhD, Rabi Hanna, MD, Seth J. Corey, MD, Jaroslaw P. Maciejewski

Blood (2018) 132 (Supplement 1): 4389.

https://doi.org/10.1182/blood-2018-99-116554

Published: 2018

Journal Articles

SNP-Array Genome Wide Association Study Meta-Analysis Identifies Innate Immune Susceptibility Loci Associated with Non-Del(5q) Myelodysplastic Syndromes Predisposition

Blood (2018) 132 (Supplement 1): 107.

https://doi.org/10.1182/blood-2018-99-118747

Published: 2018

Journal Articles

Paroxysmal Nocturnal Hemoglobinuria Results from Initial Clonal PIG-a Mosaicism

Michael J. Clemente, Bartlomiej Przychodzen, Cassandra M. Hirsch, BS, Bhumika J. Patel, MD, Taha Bat, Yasunobu Nagata, MD PhD, Marcin W. Wlodarski, MD PhD, Hideki Makishima, MD PhD, Jaroslaw P. Maciejewski, PhD MD FACP

Blood (2017) 130 (Supplement 1): 1179.

https://doi.org/10.1182/blood.V130.Suppl_1.1179.1179

Published: 2017

Journal Articles

Clinical and Molecular Characteristics of Therapy-Related Acute Lymphoblastic Leukemia

Blood (2017) 130 (Supplement 1): 3993.

https://doi.org/10.1182/blood.V130.Suppl_1.3993.3993

Published: 2017

Journal Articles

Mutational Signatures Associated with Intensity and Duration of Smoking in Myelodysplastic Syndromes (MDS)

Yazan F. Madanat, MD, Tomas Radivoyevitch, PhD, Aziz Nazha, MD, Yazeed Sawalha, MD, Karam Al-Issa, MD, Nour Abuhadra, MD, Teodora Kuzmanovic, BA, Bartlomiej Przychodzen, Cassandra M. Hirsch, BS, Bhumika J. Patel, MD, David Seastone, PhDDO, Yogenthiran Saunthararajah, MD, Sudipto Mukherjee, MD PhD MPH, Anjali S. Advani, MD, Hetty E. Carraway, MD MBA, Aaron T. Gerds, MDMS, Jaroslaw P. Maciejewski, PhD MD FACP, Mikkael A. Sekeres, MD MS

Blood (2017) 130 (Supplement 1): 424.

https://doi.org/10.1182/blood.V130.Suppl_1.424.424

Published: 2017

Journal Articles

Mutations in DNMT3A , U2AF1 , and EZH2 Identify Intermediate-Risk Acute Myeloid Leukemia Patients with Poor Outcome after CR1

Caner Saygin, MD, Cassandra M. Hirsch, BS, Bartlomiej Przychodzen, M.S., Mikkael A. Sekeres, MD MS, Betty K. Hamilton, MD, Matt Kalaycio, MD, Hetty E. Carraway, MD MBA, Aaron T. Gerds, MDMS, Sudipto Mukherjee, MD PhD MPH, Aziz Nazha, MD, Ronald Sobecks, MD, Christopher Goebel, Donna M. Abounader, Jaroslaw P. Maciejewski, PhD MD FACP, Anjali S. Advani, MD

Blood (2017) 130 (Supplement 1): 2665.

https://doi.org/10.1182/blood.V130.Suppl_1.2665.2665

Published: 2017

Journal Articles

Transcriptome of DNA Repair Genes in CMML: Rationale for Targeting ERCC1 and CDKN1A As a Synthetic Lethality Approach

Blood (2017) 130 (Supplement 1): 1679.

https://doi.org/10.1182/blood.V130.Suppl_1.1679.1679

Published: 2017

Journal Articles

Origins of myelodysplastic syndromes after aplastic anemia

Eiju Negoro, Yasunobu Nagata, Michael J. Clemente, Naoko Hosono, Wenyi Shen, Aziz Nazha, Tetsuichi Yoshizato, Cassandra Hirsch, Bartlomiej Przychodzen, Reda Z. Mahfouz, Teodora Kuzmanovic, Mikkael A. Sekeres, Hideki Makishima, Seishi Ogawa, Jaroslaw P. Maciejewski

Blood (2017) 130 (17): 1953–1957.

https://doi.org/10.1182/blood-2017-02-767731

Published: 2017

Includes: Supplemental data

Journal Articles

Genetic abnormalities in myelodysplasia and secondary acute myeloid leukemia: impact on outcome of stem cell transplantation

Blood (2017) 129 (17): 2347–2358.

https://doi.org/10.1182/blood-2016-12-754796

Published: 2017

Includes: Supplemental data

Journal Articles

PHF6 - Somatic Mutations and Their Role in Pathophysiology of MDS and AML

Bartlomiej Przychodzen, MSc, Xiaorong Gu, PhD, Dewen You, PhD, Cassandra M. Hirsch, Michael J. Clemente, Aaron D. Viny, MD MS, Ross L. Levine, MD, Torsten Haferlach, Manja Maggendorfer, Mikkael A. Sekeres, MD MS, Hetty E. Carraway, MD MBA, Aziz Nazha, MD, Francis Enane, Jaroslaw P. Maciejewski, MD PhD

Blood (2015) 126 (23): 1259.

https://doi.org/10.1182/blood.V126.23.1259.1259

Published: 2015

Journal Articles

Activation of the Unfolded Protein Response with the First-in-Class P97 Inhibitor CB-5083 Induces Stable Disease Regression and Overcomes Ara-C Resistance in AML

Steffan T. Nawrocki, PhD, Yingchun Han, MD, Ronan LE Moigne, PhD, Valeria Visconte, PhD, Bartlomiej Przychodzen, MSc, Mark Rolfe, PhD, Stevan Djakovic, PhD, Daniel Anderson, David Wustrow, PhD, Han-Jie Zhou, Steve Wong, PhD, Anjali Advani, MD, Hetty E. Carraway, MD MBA, Jaroslaw P. Maciejewski, MD PhD, Mikkael A. Sekeres, MD MS, Kevin R. Kelly, MD PhD, Jennifer S. Carew, PhD

Blood (2015) 126 (23): 1350.

https://doi.org/10.1182/blood.V126.23.1350.1350

Published: 2015

Journal Articles

Whole-Exome Sequencing Identifies Germline IDH2 and IDH3 mutations That Predispose to Myeloid Neoplasms

Remco Molenaar, M.Sc., Srinivasa Reddy Sanikommu, MD, Bhumika J. Patel, Bartlomiej Przychodzen, MSc, Cornelis J van Noorden, PhD, Tomas Radivoyevitch, PhD, Hideki Makishima, MD PhD, Hetty E. Carraway, MD MBA, Jaroslaw P. Maciejewski, MD PhD

Blood (2015) 126 (23): 1405.

https://doi.org/10.1182/blood.V126.23.1405.1405

Published: 2015

Journal Articles

Outcome of Newly Diagnosed Acute Myeloid Leukemia (AML) Refractory to 1 or 2 Cycles of Induction Chemotherapy

Ahmad Zarzour, MD, Aziz Nazha, MD, Matt Kalaycio, MD, Bhumika J. Patel, Aaron T. Gerds, MD MS, Michael J. Clemente, Cassandra M Hirsch, Jennifer S. Carew, PhD, Anjali S. Advani, MD, Srinivasa R. Sanikommu, MBBS, Bartlomiej Przychodzen, MSc, Hetty E. Carraway, MD MBA, Sudipto Mukherjee, MD PhD, Jaroslaw P. Maciejewski, MD PhD, Mikkael A. Sekeres, MD MS

Blood (2015) 126 (23): 1319.

https://doi.org/10.1182/blood.V126.23.1319.1319

Published: 2015

NARROW

Rare Germline Alterations of Myeloperoxidase Predispose to Myeloid Neoplasms and Are Associated with Increased Circulating Burden of Microbial DNA

Pharmacologic Normalization of Altered Transcriptome of SF3B1 Mutant Myeloid Neoplasia

The Biological Inferences from the Ranking of SF3B1 Mutations in the Clonal Hierarchy of Myeloid Neoplasia

Molecular Dissection of Del(5q): Distinction between Primary and Secondary Del(5q) and Pathogenetic Implications

Therapeutic Applications of a Unique Calcium Channel Blocker to Target SF3B1 MDS

Angioimmunoblastic T-Cell Lymphoma: Molecular Characterization of Clonal T and B-Cells and a Patient Derived Xenograft Model of Coexisting T and B-Cell Proliferations

Integrated Analysis of Copy-Number Alterations and Gene Mutations in 2,000 Patients with Myeloid Neoplasms

Molecular Spectrum of CSF3R variants Correlate with Specific Myeloid Malignancies and Secondary Mutations

SNP-Array Genome Wide Association Study Meta-Analysis Identifies Innate Immune Susceptibility Loci Associated with Non-Del(5q) Myelodysplastic Syndromes Predisposition

Paroxysmal Nocturnal Hemoglobinuria Results from Initial Clonal PIG-a Mosaicism

Clinical and Molecular Characteristics of Therapy-Related Acute Lymphoblastic Leukemia

Mutational Signatures Associated with Intensity and Duration of Smoking in Myelodysplastic Syndromes (MDS)

Mutations in DNMT3A , U2AF1 , and EZH2 Identify Intermediate-Risk Acute Myeloid Leukemia Patients with Poor Outcome after CR1

Transcriptome of DNA Repair Genes in CMML: Rationale for Targeting ERCC1 and CDKN1A As a Synthetic Lethality Approach

Origins of myelodysplastic syndromes after aplastic anemia

Genetic abnormalities in myelodysplasia and secondary acute myeloid leukemia: impact on outcome of stem cell transplantation

PHF6 - Somatic Mutations and Their Role in Pathophysiology of MDS and AML

Activation of the Unfolded Protein Response with the First-in-Class P97 Inhibitor CB-5083 Induces Stable Disease Regression and Overcomes Ara-C Resistance in AML

Whole-Exome Sequencing Identifies Germline IDH2 and IDH3 mutations That Predispose to Myeloid Neoplasms

Outcome of Newly Diagnosed Acute Myeloid Leukemia (AML) Refractory to 1 or 2 Cycles of Induction Chemotherapy

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American Society of Hematology

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American Society of Hematology

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