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Journal Articles

Paroxysmal nocturnal hemoglobinuria–related thrombosis in the era of novel therapies: a 2043-patient-year analysis

Carmelo Gurnari, Hussein Awada, Simona Pagliuca, Danai Dima, Fauzia Ullah, Naomi Kawashima, Yasuo Kubota, Ceylan Colak, Valeria Visconte, Bhumika J. Patel, Vikram Dhillon, Naimisha Marneni, Suresh Kumar Balasubramanian, Ashwin Kishtagari, Taha Bat, Jaroslaw P. Maciejewski

Blood (2024) 144 (2): 145–155.

https://doi.org/10.1182/blood.2024023988

Published: 2024

Journal Articles

Phase 1b/2 Study of Escalating Doses of the NEDD8 Activating Enzyme Inhibitor Pevonedistat Administered in Combination with Standard Induction Therapy (Cytarabine and Idarubicin) in Newly Diagnosed High Risk Acute Myeloid Leukemia

Blood (2023) 142 (Supplement 1): 4279.

https://doi.org/10.1182/blood-2023-185481

Published: 2023

Journal Articles

Molecular Patterns Identify Distinct Subclasses of Myeloid Neoplasia

Blood (2022) 140 (Supplement 1): 6881–6883.

https://doi.org/10.1182/blood-2022-165603

Published: 2022

Journal Articles

New Approaches to Chronic Idiopathic Neutropenia in the Era of Clonal Hematopoiesis

Olisaemeka Ogbue, Tariq Kewan, Waled Bahaj, Carmelo Gurnari, Valeria Visconte, Suresh Kumar Balasubramanian, Bhumika J. Patel, Alan Lichtin, MD, Hetty E. Carraway, Jaroslaw P. Maciejewski

Blood (2022) 140 (Supplement 1): 2916–2917.

https://doi.org/10.1182/blood-2022-163808

Published: 2022

Journal Articles

Clinico-Molecular Risk Factors and Management of Thrombosis in a Large Real-Life Cohort of Patients with Paroxysmal Nocturnal Hemoglobinuria in the New Era of Anti-Complement Inhibitors and Doacs

Carmelo Gurnari, Hussein Awada, Mai Aly, Danai Dima, Fauzia Ullah, Naomi Kawashima, Yasuo Kubota, Ceylan Colak, Valeria Visconte, Simona Pagliuca, Bhumika J. Patel, Taha Bat, Jaroslaw P. Maciejewski

Blood (2022) 140 (Supplement 1): 8513–8514.

https://doi.org/10.1182/blood-2022-160479

Published: 2022

Journal Articles

Molecular and Clinical Spectra of Protein Phosphatase, Mg2+/Mn2+-Dependent 1D ( PPM1D )-Mutant Myeloid Neoplasms

Mai M M Aly, Valeria Visconte, Carmelo Gurnari, Reem Alagooz, Arda Durmaz, Suresh Kumar Balasubramanian, Abhay Singh Singh, Bhumika J. Patel, Tariq Kewan, Waled Bahaj, Jaroslaw P. Maciejewski

Blood (2022) 140 (Supplement 1): 12298–12300.

https://doi.org/10.1182/blood-2022-160332

Published: 2022

Journal Articles

ANKRD26 Coding Variants in Myeloid Neoplasia

Teodora Kuzmanovic, Metis Hasipek, Samuel Li, Thomas Laframboise, Valeria Visconte, Sunisa Kongkiatkamon, Seth J. Corey, Sudipto Mukherjee, Anjali Advani, Aaron T. Gerds, Yogenthiran Saunthararajah, Sophia R. Balderman, Abhay Singh Singh, Hetty E. Carraway, Niroshan Nadarajah, Manja Meggendorfer, Jaroslaw P. Maciejewski, Bhumika J. Patel

Blood (2022) 140 (Supplement 1): 4013–4015.

https://doi.org/10.1182/blood-2022-170645

Published: 2022

Journal Articles

The similarity of class II HLA genotypes defines patterns of autoreactivity in idiopathic bone marrow failure disorders

Blood (2021) 138 (26): 2781–2798.

https://doi.org/10.1182/blood.2021012900

Published: 2021

Includes: Supplemental data

Journal Articles

Molecular Derivation of Extramedullary Myeloid Sarcomas Based on Machine Learning Analysis of Genomic Clusters in AML

Tariq Kewan, Carmelo Gurnari, Waled Bahaj, Simona Pagliuca, Hassan Awada, Suresh Kumar Balasubramanian, Bhumika J. Patel, Sudipto Mukherjee, Anjali Advani, Valeria Visconte, Hetty E. Carraway, James R. Cook, Heesun J. Rogers, Jaroslaw P. Maciejewski

Blood (2021) 138 (Supplement 1): 1295.

https://doi.org/10.1182/blood-2021-151803

Published: 2021

Journal Articles

Immunogenetic, Molecular and Clinical Determinants of Clonal Evolution in Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria

Blood (2021) 138 (Supplement 1): 602.

https://doi.org/10.1182/blood-2021-147556

Published: 2021

Journal Articles

Germline and Somatic Variants of CSF3R Define Distinct Myeloid Neoplasia Syndromes

Tariq Kewan, Hrishikesh M Mehta, Carmelo Gurnari, Waled Bahaj, Simona Pagliuca, Suresh Kumar Balasubramanian, Bhumika J. Patel, Anjali Advani, Valeria Visconte, Hetty E. Carraway, Seth J. Corey, Jaroslaw P. Maciejewski

Blood (2021) 138 (Supplement 1): 3667.

https://doi.org/10.1182/blood-2021-152546

Published: 2021

Journal Articles

A Novel Machine Learning-Derived Molecular Classification Scheme with Prognostic Significance

Tariq Kewan, Arda Durmaz, Hassan Awada, Carmelo Gurnari, Waled Bahaj, Simona Pagliuca, Laila Terkawi, Ramsha Ahmed, Suresh Kumar Balasubramanian, Bhumika J. Patel, Hetty E. Carraway, Valeria Visconte, Torsten Haferlach, Jaroslaw P. Maciejewski

Blood (2021) 138 (Supplement 1): 3666.

https://doi.org/10.1182/blood-2021-152443

Published: 2021

Journal Articles

Immunodynamics of Paroxysmal Nocturnal Hemoglobinuria

Carmelo Gurnari, Simona Pagliuca, Adam Wahida, Tariq Kewan, Waled Bahaj, Minako Mori, Bhumika J. Patel, Kewal Asosingh, Valeria Visconte, Jaroslaw P. Maciejewski

Blood (2021) 138 (Supplement 1): 1107.

https://doi.org/10.1182/blood-2021-148934

Published: 2021

Journal Articles

Co-Occurrence of MDS with MGUS Represents a Unique Disease Entity with Specific Molecular Phenotype and Potential Improved Clinical Outcome

Tariq Kewan, Ramsha Ahmed, Carmelo Gurnari, Waled Bahaj, Simona Pagliuca, Yogenthiran Saunthararajah, Bhumika J. Patel, Sudipto Mukherjee, Aaron T. Gerds, Anjali Advani, Valeria Visconte, Jaroslaw P. Maciejewski, Hetty E. Carraway

Blood (2021) 138 (Supplement 1): 1529.

https://doi.org/10.1182/blood-2021-151858

Published: 2021

Journal Articles

A Phase II Study of CPX-351 As a Novel Therapeutic Approach for Patients with Myelodysplastic Syndromes (MDS) after Hypomethylating Agent Failure

Aziz Nazha, MD, Sudipto Mukherjee, MD PhD MPH, Anjali S Advani, MD, Madeline Waldron, PharmD, BCOP, Caitlin Siebenaller, PharmD, Jenna Thomas, Eric Parsons, RN, Hetty E. Carraway, MD MBA, Aaron T. Gerds, MDMS, Bhumika J. Patel, MD, Mikkael A. Sekeres, MD MS

Blood (2020) 136 (Supplement 1): 1.

https://doi.org/10.1182/blood-2020-139515

Published: 2020

Journal Articles

Impact of Pathogenic Germ Line Variants in Adults with Acquired Bone Marrow Failure Syndromes Vs . Myeloid Neoplasia

Misam Zawit, MBBS, Jibran Durrani, MD, Wenyi Shen, MD, Vera Adema, PhD, Cassandra M Kerr, MS, Hassan Awada, MD, Sunisa Kongkiatkamon, MD, Carmelo Gurnari, MD, Simona Pagliuca, MD, Laila Terkawi, Bhumika J. Patel, MD, Valeria Visconte, PhD, Hetty E. Carraway, MD MBA, Thomas LaFramboise, PhD, Seth J. Corey, MD, Torsten Haferlach, MD, Jaroslaw P. Maciejewski, MD PhD

Blood (2020) 136 (Supplement 1): 1.

https://doi.org/10.1182/blood-2020-142586

Published: 2020

Journal Articles

Impact of HLA Evolutionary Divergence on Clinical Features of Patients with Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria

Simona Pagliuca, MD, Carmelo Gurnari, MD, Diego Chowell, PhD, Chirag Krishna, Bhumika J. Patel, MD, Hassan Awada, MD, Cassandra M Kerr, MS, Sunisa Kongkiatkamon, MD, Ashwin Kishtagari, MBBS, Thomas Laframboise, PhD, Yogenthiran Saunthararajah, MD, Babal K. Jha, PhD, Valeria Visconte, PhD, Timothy Chan, MD PhD, Jaroslaw Maciejewski, PhD

Blood (2020) 136 (Supplement 1): 2–3.

https://doi.org/10.1182/blood-2020-142693

Published: 2020

Journal Articles

The Genomic Landscape of Myeloid Neoplasms Evolved from AA/PNH

Carmelo Gurnari, MD, Simona Pagliuca, MD, Bhumika J. Patel, MD, Hassan Awada, MD, Cassandra M Kerr, MS, Wenyi Shen, MD, Sunisa Kongkiatkamon, MD, Laila Terkawi, Misam Zawit, MBBS, Jibran Durrani, MD, Valeria Visconte, PhD, Seth J. Corey, MD, Maria Teresa Voso, MD, Hetty E. Carraway, MD MBA, Jaroslaw P. Maciejewski, MD PhD

Blood (2020) 136 (Supplement 1): 2.

https://doi.org/10.1182/blood-2020-140045

Published: 2020

Journal Articles

Immunogenomics of Aplastic Anemia: The Role of HLA Somatic Mutations and the HLA Evolutionary Divergence

Simona Pagliuca, MD, Carmelo Gurnari, MD, Hassan Awada, MD, Cassandra M Kerr, MS, Bhumika J. Patel, MD, Laila Terkawi, Misam Zawit, MBBS, Sunisa Kongkiatkamon, MD, Pedro H Prata, MD, Ashwin Kishtagari, MBBS, Adam Wahida, Thomas Laframboise, PhD, Valeria Visconte, PhD, Regis Peffault De Latour, MD PhD, Jaroslaw P. Maciejewski, MD PhD

Blood (2020) 136 (Supplement 1): 20–21.

https://doi.org/10.1182/blood-2020-142501

Published: 2020

Journal Articles

Molecular and Expression Characterization of Monosomy 7 and Del(7q)

Vera Adema, PhD, Cassandra M Kerr, MS, Hassan Awada, MD, Sunisa Kongkiatkamon, MD, Bhumika J. Patel, MD, Mikkael A. Sekeres, MD MS, Valeria Visconte, PhD, John Barnard, Jaroslaw P. Maciejewski, MD PhD, Torsten Haferlach, MD

Blood (2020) 136 (Supplement 1): 33.

https://doi.org/10.1182/blood-2020-142507

Published: 2020

NARROW

Paroxysmal nocturnal hemoglobinuria–related thrombosis in the era of novel therapies: a 2043-patient-year analysis

Phase 1b/2 Study of Escalating Doses of the NEDD8 Activating Enzyme Inhibitor Pevonedistat Administered in Combination with Standard Induction Therapy (Cytarabine and Idarubicin) in Newly Diagnosed High Risk Acute Myeloid Leukemia

Molecular Patterns Identify Distinct Subclasses of Myeloid Neoplasia

New Approaches to Chronic Idiopathic Neutropenia in the Era of Clonal Hematopoiesis

Clinico-Molecular Risk Factors and Management of Thrombosis in a Large Real-Life Cohort of Patients with Paroxysmal Nocturnal Hemoglobinuria in the New Era of Anti-Complement Inhibitors and Doacs

Molecular and Clinical Spectra of Protein Phosphatase, Mg2+/Mn2+-Dependent 1D ( PPM1D )-Mutant Myeloid Neoplasms

ANKRD26 Coding Variants in Myeloid Neoplasia

The similarity of class II HLA genotypes defines patterns of autoreactivity in idiopathic bone marrow failure disorders

Molecular Derivation of Extramedullary Myeloid Sarcomas Based on Machine Learning Analysis of Genomic Clusters in AML

Immunogenetic, Molecular and Clinical Determinants of Clonal Evolution in Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria

Germline and Somatic Variants of CSF3R Define Distinct Myeloid Neoplasia Syndromes

A Novel Machine Learning-Derived Molecular Classification Scheme with Prognostic Significance

Immunodynamics of Paroxysmal Nocturnal Hemoglobinuria

Co-Occurrence of MDS with MGUS Represents a Unique Disease Entity with Specific Molecular Phenotype and Potential Improved Clinical Outcome

A Phase II Study of CPX-351 As a Novel Therapeutic Approach for Patients with Myelodysplastic Syndromes (MDS) after Hypomethylating Agent Failure

Impact of Pathogenic Germ Line Variants in Adults with Acquired Bone Marrow Failure Syndromes Vs . Myeloid Neoplasia

Impact of HLA Evolutionary Divergence on Clinical Features of Patients with Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria

The Genomic Landscape of Myeloid Neoplasms Evolved from AA/PNH

Immunogenomics of Aplastic Anemia: The Role of HLA Somatic Mutations and the HLA Evolutionary Divergence

Molecular and Expression Characterization of Monosomy 7 and Del(7q)

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American Society of Hematology

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