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Journal Articles

Loss of GABARAP mediates resistance to immunogenic chemotherapy in multiple myeloma

Annamaria Gulla, Eugenio Morelli, Megan Johnstone, Marcello Turi, Mehmet K. Samur, Cirino Botta, Selma Cifric, Pietro Folino, Delaney Vinaixa, Francesca Barello, Cole Clericuzio, Vanessa Katia Favasuli, Domenico Maisano, Srikanth Talluri, Rao Prabhala, Giada Bianchi, Mariateresa Fulciniti, Kenneth Wen, Keiji Kurata, Jiye Liu, Johany Penailillo, Alberto Bragoni, Anna Sapino, Paul G. Richardson, Dharminder Chauhan, Ruben D. Carrasco, Teru Hideshima, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Blood
Blood (2024) 143 (25): 2612–2626.
https://doi.org/10.1182/blood.2023022777
Published: 2024
Includes: Supplemental data
Journal Articles

The Spop/BRD4/c-Myc Axis Modulates IMiDs Sensitivity in Multiple Myeloma

Lijie Xing, Jiye Liu, Kenneth Wen, Teru Hideshima, Kenneth C. Anderson, Zengjun Li
Journal: Blood
Blood (2023) 142 (Supplement 1): 4687.
https://doi.org/10.1182/blood-2023-187762
Published: 2023
Journal Articles

BCMA-Targeted Bortezomib Nanotherapy (BCMA-BTZ-Nps) Targets Tumor, Enhances Therapeutic Efficacy, Triggers Immunogenic Cell Death, Overcomes Drug Resistance, and Reduces Off-Target Toxicity in Multiple Myeloma (MM)

Debasmita Dutta, Jiye Liu, Kenneth Wen, Keiji Kurata, Mariateresa Fulciniti, Annamaria Gulla, Teru Hideshima, Kenneth C. Anderson
Journal: Blood
Blood (2023) 142 (Supplement 1): 1934.
https://doi.org/10.1182/blood-2023-188237
Published: 2023
Journal Articles

BRD9 Is Essential for Ribosome Biogenesis and the Survival of Multiple Myeloma Cells

Keiji Kurata, Mehmet K. Samur, Priscilla Liow, Kenneth Wen, Leona Yamamoto, Jiye Liu, Eugenio Morelli, Annamaria Gulla, Yu-Tzu Tai, Jun Qi, Teru Hideshima, Kenneth C. Anderson
Journal: Blood
Blood (2022) 140 (Supplement 1): 596–597.
https://doi.org/10.1182/blood-2022-162445
Published: 2022
Journal Articles

Genome-Wide CRISPR-Cas9 Screen Identifies KDM6A As a Modulator of Daratumumab Sensitivity in Multiple Myeloma

Jiye Liu, Lijie Xing, Teru Hideshima, Keiji Kurata, Mehmet K. Samur, Eugenio Morelli, Kenneth Wen, Nikhil C Munshi, Kenneth C. Anderson
Journal: Blood
Blood (2022) 140 (Supplement 1): 360–361.
https://doi.org/10.1182/blood-2022-164901
Published: 2022
Journal Articles

The JAK-STAT pathway regulates CD38 on myeloma cells in the bone marrow microenvironment: therapeutic implications

Daisuke Ogiya, Jiye Liu, Hiroto Ohguchi, Keiji Kurata, Mehmet K. Samur, Yu-Tzu Tai, Sophia Adamia, Kiyoshi Ando, Teru Hideshima, Kenneth C. Anderson
Journal: Blood
Blood (2020) 136 (20): 2334–2345.
https://doi.org/10.1182/blood.2019004332
Published: 2020
Includes: Supplemental data
Journal Articles

TRAF2 Mediates Sensitivity to Immunomodulatory Drugs in the Bone Marrow Microenvironment

Jiye Liu, PhD, Teru Hideshima, MD PhD, Lijie Xing, MD, Su Wang, PhD, Daisuke Ogiya, MD PhD, Mehmet K. Samur, PhD, Nikhil C. Munshi, MD, Paul G. Richardson, MD, Kenneth Wen, Yu-Tzu Tai, PhD, Yong Cang, PhD, Kenneth Anderson, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 31.
https://doi.org/10.1182/blood-2020-139778
Published: 2020
Journal Articles

APOBEC3B Induction Following DNA Damage Response Modulates the Survival and Treatment Response in Human Multiple Myeloma

Lijie Xing, MD, Jiye Liu, PhD, Yuyin Li, PhD, Liang Lin, PhD, Kenneth Wen, Shih-Feng Cho, MD PhD, Tengteng Yu, MD PhD, Gang An, Lugui Qiu, MD PhD, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD, Yu-Tzu Tai, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4381.
https://doi.org/10.1182/blood-2019-130297
Published: 2019
Journal Articles

Syndecan-1 Is Critical in ARF6-Dependent Macropinocytosis Driven By KRAS Mutation in the Pathophysiology of Multiple Myeloma

Tengteng Yu, MD PhD, Liang Lin, PhD, Kenneth Wen, Lijie Xing, MD, Jiye Liu, PhD, Shih-Feng Cho, MD PhD, Phillip Hsieh, Ola Rizq, MD PhD, Yuyin Li, PhD, Liang Yu, Xiang Wu, Eugenio Morelli, MD, Yan Xu, MD, Gang An, MD, Nikhil C. Munshi, MD, Lugui Qiu, MD PhD, Kenneth C. Anderson, MD, Yu-Tzu Tai, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4371.
https://doi.org/10.1182/blood-2019-127454
Published: 2019
Journal Articles

TNF-α Confers Resistance of Myeloma Cells to IMiDs through TRAF2 Degradation

Jiye Liu, PhD, Teru Hideshima, MD PhD, Lijie Xing, MD, Kenneth Wen, BS, Yu-Tzu Tai, PhD, Yong Cang, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1809.
https://doi.org/10.1182/blood-2019-123141
Published: 2019
Journal Articles

JAK-STAT3 Pathway Regulates CD38 Expression on Multiple Myeloma Cells

Daisuke Ogiya, MD PhD, Jiye Liu, PhD, Hiroto Ohguchi, MD PhD, Yu-Tzu Tai, PhD, Teru Hideshima, MD PhD, Kenneth Anderson, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4440.
https://doi.org/10.1182/blood-2018-99-112425
Published: 2018
Journal Articles

APOBEC3B Is Induced By Activation of DNA Repair Pathway and Modulates the Survival and Treatment Response in Human Multiple Myeloma

Lijie Xing, MD, Jiye Liu, PhD, Liang Lin, PhD, Shih-Feng Cho, MD PhD, Kenneth Wen, BS, Tengteng Yu, MD, Phillip Hsieh, Gang An, MD, Lugui Qiu, MD PhD, Nikhil Munshi, MD, Kenneth Anderson, MD, Yu-Tzu Tai, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 407.
https://doi.org/10.1182/blood-2018-99-110317
Published: 2018
Journal Articles

An Immune Based, Anti-CD138 Targeting Antibody for the Treatment of Multiple Myeloma

Tengteng Yu, MD, Lijie Xing, MD, Liang Lin, PhD, Jiye Liu, PhD, Kenneth Wen, BS, Shih-Feng Cho, MD PhD, Phillip Hsieh, James Myette, Bharat Chaganty, Hedy Adari, Hamid Tissire, Ketan Deotale, Zach Shriver, Nikhil Munshi, MD, Yu-Tzu Tai, PhD, Kenneth Anderson, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5617.
https://doi.org/10.1182/blood-2018-99-119112
Published: 2018
Journal Articles

Anti-BCMA BiTE ® AMG 701 Potently Induces Specific T Cell Lysis of Human Multiple Myeloma (MM) Cells and Immunomodulation in the Bone Marrow Microenvironment

Shih-Feng Cho, MD PhD, Liang Lin, PhD, Lijie Xing, MD, Jiye Liu, PhD, Tengteng Yu, MD, Kenneth Wen, BS, Phillip Hsieh, Nikhil Munshi, MD, Kenneth Anderson, MD, Yu-Tzu Tai, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 592.
https://doi.org/10.1182/blood-2018-99-118425
Published: 2018
Journal Articles

Dysregulated Translational Control Is a Central Feature of MM Mediated By 14-3-3ε Interactome Promoting Multiple Myeloma Cell Growth and Viability

Yan Xu, MD, Mariateresa Fulciniti, PhD, Matthew Ho, Mehmet Kemal Samur, PhD, Michael A Lopez, Na Li, MD, Giada Bianchi, MD, Raphael Szalat, MD, Jianhong Lin, MD MSc, Tommaso Perini, MD, Srikanth Talluri, PhD, Tengteng Yu, MD, Kenneth Wen, BS, Jiye Liu, PhD, Li Zhang, MD, Liang Lin, PhD, Lijie Xing, MD, Gang An, MD, Yu-Tzu Tai, PhD, Kenneth Anderson, MD, Lugui Qiu, MD PhD, Nikhil Munshi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3176.
https://doi.org/10.1182/blood-2018-99-118994
Published: 2018
Journal Articles

Genome-Wide CRISPR-Cas9 Screening Reveals a Role for TRAF2 in Resistance to IMiDs in Multiple Myeloma

Jiye Liu, PhD, Wenrong Zhou, PhD, Lijie Xing, MD, Liang Lin, PhD, Kenneth Wen, BS, Yu-Tzu Tai, PhD, Teru Hideshima, MD PhD, Yong Cang, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1917.
https://doi.org/10.1182/blood-2018-99-111962
Published: 2018
Journal Articles

Novel Mechanisms Underlying IMiDs Resistance in Multiple Myeloma: Therapeutic Implications

Jiye Liu, PhD, Wenrong Zhou, PhD, Lijie Xing, MD, Matthew Ho, Kenneth Wen, BS, Tianyu Song, Yu-Tzu Tai, PhD, Teru Hideshima, MD PhD, Yong Cang, PhD, Kenneth C Anderson, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 594.
https://doi.org/10.1182/blood.V130.Suppl_1.594.594
Published: 2017
Journal Articles

CD8+ Anti-BCMA mRNA CAR T-Cells Effectively Kill Human Multiple Myeloma Cells In Vitro and In Vivo

Liang Lin, PhD, Lijie Xing, MD, Chirag M Acharya, MBBS, Kenneth Wen, BS, Jiye Liu, PhD, Phillip Hsieh, Metin Kurtoglu, MD PhD, Jeffrey Holderness, MD, Murat Kalayoglu, MD PhD, Nikhil Munshi, MD, Paul G Richardson, MD, Kenneth C Anderson, MD, Yu-Tzu Tai, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3067.
https://doi.org/10.1182/blood.V130.Suppl_1.3067.3067
Published: 2017
Journal Articles

Ywhae Located on Chromosome 17p13 Promotes Myeloma Cells Proliferation Via Induction of Anti-Apoptosis and Survival Signaling Pathways

Yan Xu, MD, Mariateresa Fulciniti, PhD, Mehmet Kemal Samur, PhD, Raphael Szalat, MD, Matthew Ho, Michael A Lopez, BS, Na Li, MD, Jianhong Lin, MD MSc, Tommaso Perini, MD, Srikanth Talluri, PhD, Jiye Liu, PhD, Kenneth Wen, BS, Giada Bianchi, MD, Li Zhang, MD, Lijie Xing, MD, An Gang, MD, Liang Lin, PhD, Yu-Tzu Tai, PhD, Lugui Qiu, MD, Kenneth C Anderson, MD, Nikhil Munshi, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1755.
https://doi.org/10.1182/blood.V130.Suppl_1.1755.1755
Published: 2017
Journal Articles

Blocking HDAC3 in Bone Marrow Stromal Cells Has Direct Anti-Multiple Myeloma Effect and Modulates T Cell Function

Matthew Ho, Jiye Liu, PhD, Alireza Kalbasi, PharmD, Takeshi Harada, MDPhD, Teru Hideshima, MD PhD, Paul Dowling, BSc, PhD, Yu-Tzu Tai, PhD, Li Zhang, MD, Kenneth Wen, BS, Ralph Mazitschek, Amanda McCann, Kenneth C Anderson, MD, Peter O'Gorman, MD PhD FRCP, FRCPath, Giada Bianchi, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4429.
https://doi.org/10.1182/blood.V130.Suppl_1.4429.4429
Published: 2017