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Carl D. Novina
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Journal Articles

A MIR17HG-derived long noncoding RNA provides an essential chromatin scaffold for protein interaction and myeloma growth

Eugenio Morelli, Mariateresa Fulciniti, Mehmet K. Samur, Caroline F. Ribeiro, Leon Wert-Lamas, Jon E. Henninger, Annamaria Gullà, Anil Aktas-Samur, Katia Todoerti, Srikanth Talluri, Woojun D. Park, Cinzia Federico, Francesca Scionti, Nicola Amodio, Giada Bianchi, Megan Johnstone, Na Liu, Doriana Gramegna, Domenico Maisano, Nicola A. Russo, Charles Lin, Yu-Tzu Tai, Antonino Neri, Dharminder Chauhan, Teru Hideshima, Masood A. Shammas, Pierfrancesco Tassone, Sergei Gryaznov, Richard A. Young, Kenneth C. Anderson, Carl D. Novina, Massimo Loda, Nikhil C. Munshi
Journal: Blood
Blood (2023) 141 (4): 391–405.
https://doi.org/10.1182/blood.2022016892
Published: 2023
Includes: Supplemental data
Journal Articles

Bioprocessing of MIR17HG Results in Long and Short Noncoding RNAs with Targetable Tumor-Promoting Activity in Multiple Myeloma

Eugenio Morelli, Annamaria Gulla, Na Liu, Domenico Maisano, Anil Aktas-Samur, Nicola Amodio, Caroline Ribeiro, Leon Wert-Lamas, Jonathan Henninger, Srikanth Talluri, Megan Johnstone, Doriana Gramegna, Delaney Vinaixa, Antonino Neri, Dharminder Chauhan, Teru Hideshima, Masood A. Shammas, Pierfrancesco Tassone, Sergei Gryaznov, Richard A. Young, Kenneth C. Anderson, Carl D. Novina, Massimo Loda, Mariateresa Fulciniti, Mehmet K. Samur, Nikhil C Munshi
Journal: Blood
Blood (2022) 140 (Supplement 1): 1551–1552.
https://doi.org/10.1182/blood-2022-167604
Published: 2022
Journal Articles

Identifying Long Noncoding RNA Dependencies Using CRISPR Interference (CRISPRi)-Based Platform in Multiple Myeloma

Eugenio Morelli, Anil Aktas-Samur, Mehmet K. Samur, Annamaria Gulla, Leon Wert-Lamas, Caroline Ribeiro, Jonathan E Henninger, Woojun D Park, Nicola Amodio, Doriana Gramegna, Megan Johnstone, Pierfrancesco Tassone, Yu-Tzu Tai, Carl D. Novina, Richard A. Young, Massimo Loda, Masood A. Shammas, Sergei Gryaznov, Mariateresa Fulciniti, Kenneth C. Anderson, Nikhil C. Munshi
Journal: Blood
Blood (2021) 138 (Supplement 1): 894.
https://doi.org/10.1182/blood-2021-151705
Published: 2021
Journal Articles

RNA Regulator of Lipogenesis (RROL) Is a Novel Lncrna Mediating Protein-Protein Interaction at Gene Regulatory Loci Driving Lipogenic Programs in Multiple Myeloma

Eugenio Morelli, MD, Mariateresa Fulciniti, PhD, Mehmet K. Samur, PhD, Caroline Ribeiro, PhD, Leon Wert-Lamas, PhD, Annamaria Gulla, MD, Anil Aktas-Samur, PhD, Katia Todoerti, PhD, Srikanth Talluri, PhD, Woojun Daniel Park, Jonathan E Henninger, Cinzia Federico, PhD, Giada Bianchi, MD, Francesca Scionti, PhD, Yao Yao, Nicola Amodio, PhD, Charles Y Lin, PhD, Yu-Tzu Tai, PhD, Pierfrancesco Tassone, MD, Antonino Neri, MD, Dharminder Chauhan, PhD, Teru Hideshima, MD PhD, Richard A. Young, PhD, Kenneth Anderson, MD, Carl D. Novina, MD PhD, Massimo Loda, MD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 20–21.
https://doi.org/10.1182/blood-2020-142514
Published: 2020
Journal Articles

Targeting Myeloma Cell Metabolism Via Disruption of the Lnc-17-92 Transcriptional Program: Druggable New Vulnerability in Multiple Myeloma

Eugenio Morelli, MD, Mariateresa Fulciniti, PhD, Mehmet Kemal Samur, PhD, Caroline Ribeiro, PhD, Leon Wert-Lamas, PhD, Annamaria Gulla, MD, Anil Aktas Samur, PhD, Cinzia Federico, PhD, Francesca Scionti, PhD, Yao Yao, PhD, Nicola Amodio, PhD, Giada Bianchi, MD, Yu-Tzu Tai, PhD, Pierfrancesco Tassone, MD, Kenneth C. Anderson, MD, Carl D. Novina, MD PhD, Massimo Loda, MD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 317.
https://doi.org/10.1182/blood-2019-130730
Published: 2019
Journal Articles

Fetal Erythropoiesis Is Defective in Rpl11 Heterozygous Mice and Increases in Severity in Young Animals

Dolly Thomas, PhD, Cailin Joyce, PhD, Robert A. Redd, MS, Bertil Glader, MD, Steven Ellis, PhD, Donna S. Neuberg, ScD, Meaghan McGuinness, BS, Colin A. Sieff, MB, BCh, Carl D. Novina, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 872.
https://doi.org/10.1182/blood.V130.Suppl_1.872.872
Published: 2017
Journal Articles

The Activated TGFβ Pathway in Shwachman Diamond Syndrome Impairs Hematopoiesis and Is Down-Regulated By Deletion of 7q

Melisa Ruiz-Gutierrez, MD PhD, Cailin Joyce, PhD, Ozge Vargel Bolukbasi, PhD, Andriana Kotini, PhD, Gabriela Alexe, Jennifer Whangbo, MD PhD, David Russell, MDPhD, Kimberly Stegmaier, MD, Carl D. Novina, MD PhD, Eirini P. Papapetrou, MD PhD, Akiko Shimamura, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 875.
https://doi.org/10.1182/blood.V130.Suppl_1.875.875
Published: 2017
Journal Articles

Modeling Bone Marrow Failure and MDS in Shwachman Diamond Syndrome Using Induced Pluripotent Stem Cells

Melisa Ruiz-Gutierrez, MD PhD, Ozge Vargel Bolukbasi, PhD, Linda Vo, Ryohichi Sugimura, MD PhD, Marilyn Sanchez Bonilla, MS, Andriana Kotini, PhD, Carl D. Novina, MD PhD, George Q. Daley, MD PhD, Eirini P. Papapetrou, MD PhD, Akiko Shimamura, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1496.
https://doi.org/10.1182/blood.V128.22.1496.1496
Published: 2016
Journal Articles

Single Cell Transcriptional Profiling Reveals Activation of TNF-Alpha Signaling in Hematopoietic Stem and Progenitor Cells from Shwachman-Diamond Syndrome Patients

Cailin Joyce, PhD, Assieh Saadatpour, PhD, Lan Jiang, PhD, Melisa Ruiz-Gutierrez, MDPhD, Ozge Vargel Bolukbasi, PhD, Inga Hofmann, MD, Colin A. Sieff, MB.BCh, Chad Nusbaum, PhD, Akiko Shimamura, MD PhD, Guo-Cheng Yuan, PhD, Carl D. Novina, MDPhD
Journal: Blood
Blood (2016) 128 (22): 335.
https://doi.org/10.1182/blood.V128.22.335.335
Published: 2016
Journal Articles

A Novel Conditional Knockout of the Diamond Blackfan Anemia Gene Rpl11 Shows Failure of Erythropoiesis, a Marked Increase in BFU-E Progenitors By Phenotype That Proliferate Poorly in Culture, and Activation of p53 Target Genes

Cailin E Joyce, PhD, Meaghan McGuinness, BS, Rebekka K Schneider, MD, Mark D. Fleming, MD DPhil, Dean R Campagna, BS, Paul J Schmidt, PhD, Benjamin L Ebert, MD PhD, Carl D. Novina, MDPhD, Colin A. Sieff, MB.BCh
Journal: Blood
Blood (2015) 126 (23): 1205.
https://doi.org/10.1182/blood.V126.23.1205.1205
Published: 2015
Journal Articles

microRNA expression in the biology, prognosis, and therapy of Waldenström macroglobulinemia

Aldo M. Roccaro, Antonio Sacco, Changzhong Chen, Judith Runnels, Xavier Leleu, Feda Azab, Abdel Kareem Azab, Xiaoying Jia, Hai T. Ngo, Molly R. Melhem, Nicholas Burwick, Lyuba Varticovski, Carl D. Novina, Barrett J. Rollins, Kenneth C. Anderson, Irene M. Ghobrial
Journal: Blood
Blood (2009) 113 (18): 4391–4402.
https://doi.org/10.1182/blood-2008-09-178228
Published: 2009
Includes: Supplemental data
Journal Articles

MicroRNA Signature in Waldenstrom Macroglobulinemia

Aldo M Roccaro, Antonio Sacco, Changzhong Chen, Xavier Leleu, Judith Runnels, Feda Azab, Abdel Kareem Azab, Xiaoying Jia, Hai T Ngo, Molly R. Melhem, Nicholas Burwick, Phong Quang, Lyuba Varticovski, Carl D Novina, Barrett J. Rollins, Kenneth C. Anderson, Irene M. Ghobrial
Journal: Blood
Blood (2008) 112 (11): 630.
https://doi.org/10.1182/blood.V112.11.630.630
Published: 2008