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Journal Articles

Genetic Mutation and Outcome of Venetoclax-Based Therapy in Newly Diagnosed AML in the Real World: Hokkaido Leukemia Net Study

Naoki Miyashita, Masahiro Onozawa, Jun Nagai, Shota Yoshida, Hiroyuki Kimura, Toshihiro Matsukawa, Shinsuke Hirabayashi, Akio Mori, Takeshi Kondo, Daisuke Hidaka, Koichiro Minauchi, Akio Shigematsu, Junichi Hashiguchi, Tetsuyuki Igarashi, Yasutaka Kakinoki, Yutaka Tsutsumi, Hiroshi Iwasaki, Shota Yokoyama, Kentaro Wakasa, Katsuya Fujimoto, Toshimichi Ishihara, Hajime Sakai, Satoshi Iyama, Tatsuo Oyake, Takanori Teshima
Journal: Blood
Blood (2023) 142 (Supplement 1): 1470.
https://doi.org/10.1182/blood-2023-173909
Published: 2023
Journal Articles

The Real-World Outcomes of Ponatinib in 724 Patients with CML and Ph + ALL : A Post-Marketing Surveillance Study with a Special Interest in Arterial Occlusive Events in Japan

Naoto Takahashi, Takeshi Kondo, Yuji Ikari, Yoshihiro Fukumoto, Kiyohiko Hatake, Akira Masunari, Seiji Nishibayashi, Akiko Kageyama, Yasuhiko Fukuta, Arinobu Tojo
Journal: Blood
Blood (2023) 142 (Supplement 1): 4537.
https://doi.org/10.1182/blood-2023-174324
Published: 2023
Journal Articles

NGS Profile and the Mathematical Prediction Model for Venetoclax Combination Therapy in HM-Screen-Japan 02 Study

Tomoaki Ueda, Kentaro Fukushima, Naoki Hosen, Sunggi Chi, Hiroshi Haeno, Goichi Yoshimoto, Hironori Arai, Daisuke Ikeda, Kensuke Usuki, Naoto Takahashi, Naoko Hosono, Takahiro Yamauchi, Takeshi Kondo, Kazuhito Yamamoto, Junya Kuroda, Yosuke Minami
Journal: Blood
Blood (2023) 142 (Supplement 1): 5761.
https://doi.org/10.1182/blood-2023-180339
Published: 2023
Journal Articles

The Outcomes of Pregnancies in Japanese Patients with CML in the TKI Era; A Result of Nationwide Survey

Takeshi Kondo, Eri Matsuki, Tomoiku Takaku, Masaya Okada, Kazunori Murai, Chikashi Yoshida, Naoki Watanabe, Naoto Takahashi, Shinya Kimura, Itaru Matsumura
Journal: Blood
Blood (2023) 142 (Supplement 1): 1802.
https://doi.org/10.1182/blood-2023-174169
Published: 2023
Journal Articles

Prognostic Impact of CEBPA bZIP Domain Mutation in Cytogenetically Normal Acute Myeloid Leukemia

Naoki Miyashita, Masahiro Onozawa, Shota Yoshida, Hiroyuki Kimura, Shogo Takahashi, Shota Yokoyama, Toshihiro Matsukawa, Shinsuke Hirabayashi, Shinichi Fujisawa, Akio Mori, Shuichi Ota, Yasutaka Kakinoki, Yutaka Tsutsumi, Satoshi Yamamoto, Takuto Miyagishima, Takahiro Nagashima, Makoto Ibata, Hajime Kobayashi, Yoshihito Haseyama, Katsuya Fujimoto, Toshimichi Ishihara, Hajime Sakai, Takeshi Kondo, Takanori Teshima
Journal: Blood
Blood (2022) 140 (Supplement 1): 8950–8951.
https://doi.org/10.1182/blood-2022-158653
Published: 2022
Journal Articles

Clinical Features of Complex Karyotype in Newly Diagnosed Acute Myeloid Leukemia

Shota Yoshida, Masahiro Onozawa, Naoki Miyashita, Hiroyuki Kimura, Shogo Takahashi, Shota Yokoyama, Toshihiro Matsukawa, Shinsuke Hirabayashi, Akio Mori, Takeshi Kondo, Daisuke Hidaka, Koichiro Minauchi, Akio Shigematsu, Junichi Hashiguchi, Tetsuyuki Igarashi, Yasutaka Kakinoki, Yutaka Tsutsumi, Hiroshi Iwasaki, Hajime Kobayashi, Yoshihito Haseyama, Katsuya Fujimoto, Toshimichi Ishihara, Hajime Sakai, Satoshi Iyama, Takanori Teshima
Journal: Blood
Blood (2022) 140 (Supplement 1): 3210–3211.
https://doi.org/10.1182/blood-2022-157874
Published: 2022
Journal Articles

Subclinical Minute FLT3 -ITD Clone Can be Detected in Clinically FLT3 -ITD-Negative Acute Myeloid Leukemia

Shota Yokoyama, Masahiro Onozawa, Shota Yoshida, Naoki Miyashita, Hiroyuki Kimura, Shogo Takahashi, Toshihiro Matsukawa, Shinichi Fujisawa, Kosuke Miki, Daisuke Hidaka, Junichi Hashiguchi, Kentaro Wakasa, Makoto Ibata, Yukari Takeda, Akio Shigematsu, Katsuya Fujimoto, Yutaka Tsutsumi, Akio Mori, Toshimichi Ishihara, Yasutaka Kakinoki, Takeshi Kondo, Takanori Teshima
Journal: Blood
Blood (2022) 140 (Supplement 1): 9094–9095.
https://doi.org/10.1182/blood-2022-162325
Published: 2022
Journal Articles

Efficacy and Safety of Zanubrutinib in Japanese Patients with Mature B-Cell Malignancies

Takayuki Ishikawa, Masahiro Takeuchi, Kazuyuki Shimada, Kohmei Kubo, Takeshi Kondo, Katsuya Fujimoto, Tomoaki Fujisaki, Koji Nagafuji, Rika Sakai, Shingo Kurahashi, Tatsuro Jo, Kazutaka Sunami, Senji Kasahara, Tomonori Nakazato, Haiyi Guo, William Novotny, Chris Tankersley, Motohisa Takai, Hui Yao, Jinhua Zhong, Hongjie Zhu, Koji Izutsu
Journal: Blood
Blood (2022) 140 (Supplement 1): 3663–3665.
https://doi.org/10.1182/blood-2022-168696
Published: 2022
Journal Articles

Booster Effect of a Third mRNA-Based COVID-19 Vaccine Dose in Patients with Myeloid Malignancies

Akio Mori, Masahiro Onozawa, Mirei Kobayashi, Shihori Tsukamoto, Hajime Senjo, Takashi Ishio, Emi Yokoyama, Koh Izumiyama, Makoto Saito, Haruna Muraki, Masanobu Morioka, Takanori Teshima, Takeshi Kondo
Journal: Blood
Blood (2022) 140 (Supplement 1): 9781–9782.
https://doi.org/10.1182/blood-2022-159849
Published: 2022
Journal Articles

Better Prognosis of Dominant-Negative Type of IKZF1 Deletion in BCR-ABL- positive Adult B-Cell Acute Lymphoblastic Leukemia

Hiroyuki Kimura, Masahiro Onozawa, Shota Yoshida, Naoki Miyashita, Shogo Takahashi, Shota Yokoyama, Toshihiro Matsukawa, Shinsuke Hirabayashi, Shinichi Fujisawa, Shuichi Ota, Daisuke Hidaka, Akio Mori, Takeshi Kondo, Yasutaka Kakinoki, Yutaka Tsutsumi, Satoshi Yamamoto, Takuto Miyagishima, Takahiro Nagashima, Makoto Ibata, Hajime Kobayashi, Yoshihito Haseyama, Katsuya Fujimoto, Toshimichi Ishihara, Hajime Sakai, Takanori Teshima
Journal: Blood
Blood (2022) 140 (Supplement 1): 9207–9208.
https://doi.org/10.1182/blood-2022-157881
Published: 2022
Journal Articles

A Practice-Oriented Genome Profiling Study with the Novel Halo-Shape Annealing and Defer-Ligation Enrichment (HANDLE) System : HM-Screen-JAPAN02

Hironori Arai, SungGi Chi, Yoshikazu Utsu, Shinichi Masuda, Nobuyuki Aotsuka, Tomoaki Ueda, Kentaro Fukushima, Daisuke Ikeda, Naoko Hosono, Takahiro Yamauchi, Goichi Yoshimoto, Hiroto Horiguchi, Satoshi Iyama, Junya Kanda, Seiichiro Katagiri, Akihiko Gotoh, Daisuke Koyama, Takayuki Ikezoe, Takeshi Kondo, Yukinori Nakamura, Fumiya Ogasawara, Suguru Fukuhara, Koji Izutsu, Nobuhiko Yamauchi, Junichiro Yuda, Yosuke Minami
Journal: Blood
Blood (2022) 140 (Supplement 1): 10722–10724.
https://doi.org/10.1182/blood-2022-159351
Published: 2022
Journal Articles

Clinical Significance of FLT3 Mutations in a Comprehensive NGS Multicenter Study of AML: HM-Screen-Japan 01

Kentaro Fukushima, Hirohiko Shibayama, SungGi Chi, Naoko Hosono, Takahiro Yamauchi, Seiichiro Katagiri, Akihiko Gotoh, Motoki Eguchi, Takanobu Morishita, Reiki Ogasawara, Takeshi Kondo, Masamitsu Yanada, Kazuhito Yamamoto, Tsutomu Kobayashi, Junya Kuroda, Yoshimasa Kamoda, Kensuke Usuki, Yoshikazu Utsu, Nobuyuki Aotsuka, Makoto Yoshimitsu, Kenji Ishitsuka, Takaaki Ono, Naoto Takahashi, Satoshi Iyama, Makoto Nakamura, Yukinori Nakamura, Suguru Fukuhara, Koji Izutsu, Nobuhiko Yamauchi, Junichiro Yuda, Yosuke Minami
Journal: Blood
Blood (2021) 138 (Supplement 1): 2313.
https://doi.org/10.1182/blood-2021-146796
Published: 2021
Journal Articles

Non-Age-Related Neoplastic Loss of Sex Chromosomecorrelated to Prolonged Survival in CBF-AML Patients in Real-World Clinical Setting

Akio Mori, Masahiro Onozawa, Daisuke Hidaka, Shota Yokoyama, Toru Miyajima, Emi Yokoyama, Reiki Ogasawara, Koh Izumiyama, Makoto Saito, Fujisawa Shinichi, Shuichi Ota, Yasutaka Kakinoki, Yutaka Tsutsumi, Satoshi Yamamoto, Takuto Miyagishima, Takahiro Nagashima, Hiroshi Iwasaki, Hajime Kobayashi, Yoshihito Haseyama, Mitsutoshi Kurosawa, Masanobu Morioka, Takanori Teshima, Takeshi Kondo
Journal: Blood
Blood (2021) 138 (Supplement 1): 2378.
https://doi.org/10.1182/blood-2021-146276
Published: 2021
Journal Articles

High CRP-Albumin Ratio Predicts Poor Prognosis in Transplant Ineligible Elderly Patients with Newly Diagnosed Acute Myeloid Leukemia

Hajime Senjo, Masahiro Onozawa, Daisuke Hidaka, Shota Yokoyama, Satoshi Yamamoto, Yutaka Tsutsumi, Yoshihito Haseyama, Takahiro Nagashima, Akio Mori, Shuichi Ota, Hajime Sakai, Toshimichi Ishihara, Takuto Miyagishima, Yasutaka Kakinoki, Mitsutoshi Kurosawa, Hajime Kobayashi, Hiroshi Iwasaki, Takeshi Kondo, Takanori Teshima
Journal: Blood
Blood (2021) 138 (Supplement 1): 3388.
https://doi.org/10.1182/blood-2021-144832
Published: 2021
Journal Articles

Genomic Analysis of NPM1 Mutation and KMT2A ( MLL )-Rearrangement/Amplification in Japanese Patients with Acute Myeloid Leukemia: Hematologic Malignancies (HM)-Screen-Japan 01

SungGi Chi, Kentaro Fukushima, Hirohiko Shibayama, Naoko Hosono, Takahiro Yamauchi, Seiichiro Katagiri, Akihiko Gotoh, Motoki Eguchi, Takanobu Morishita, Reiki Ogasawara, Takeshi Kondo, Masamitsu Yanada, Kazuhito Yamamoto, Tsutomu Kobayashi, Junya Kuroda, Yoshimasa Kamoda, Kensuke Usuki, Yoshikazu Utsu, Nobuyuki Aotsuka, Makoto Yoshimitsu, Kenji Ishitsuka, Yasuyuki Nagata, Takaaki Ono, Naohito Fujishima, Naoto Takahashi, Hiroto Horiguchi, Satoshi Iyama, Makoto Nakamura, Kensuke Kojima, Kaoru Yamamoto, Yukinori Nakamura, Suguru Fukuhara, Koji Izutsu, Nobuhiko Yamauchi, Junichiro Yuda, Yosuke Minami
Journal: Blood
Blood (2021) 138 (Supplement 1): 4460.
https://doi.org/10.1182/blood-2021-149425
Published: 2021
Journal Articles

Properties and Distribution of IDH-1/2 Mutations in Acute Myeloid Leukemia By the Comprehensive Genomic Analysis

Satoshi Uchiyama, Nakamura Hirotaka, SungGi Chi, Kentaro Fukushima, Hirohiko Shibayama, Naoko Hosono, Takahiro Yamauchi, Seiichiro Katagiri, Akihiko Gotoh, Motoki Eguchi, Takanobu Morishita, Reiki Ogasawara, Takeshi Kondo, Masamitsu Yanada, Kazuhito Yamamoto, Tsutomu Kobayashi, Junya Kuroda, Kensuke Usuki, Nobuyuki Aotsuka, Makoto Yoshimitsu, Kenji Ishitsuka, Takaaki Ono, Naoto Takahashi, Satoshi Iyama, Makoto Nakamura, Yukinori Nakamura, Suguru Fukuhara, Koji Izutsu, Nobuhiko Yamauchi, Junichiro Yuda, Yosuke Minami
Journal: Blood
Blood (2021) 138 (Supplement 1): 4447.
https://doi.org/10.1182/blood-2021-149801
Published: 2021
Journal Articles

Genomic Analysis Focusing on RUNX1-RUNX1T1 in Japanese Patients with AML: HM-Screen-Japan 01

Seiichiro Katagiri, Daigo Akahane, Akihiko Gotoh, SungGi Chi, Kentaro Fukushima, Hirohiko Shibayama, Naoko Hosono, Takahiro Yamauchi, Motoki Eguchi, Takanobu Morishita, Reiki Ogasawara, Takeshi Kondo, Masamitsu Yanada, Kazuhito Yamamoto, Tsutomu Kobayashi, Junya Kuroda, Kensuke Usuki, Yoshikazu Utsu, Nobuyuki Aotsuka, Makoto Yoshimitsu, Kenji Ishitsuka, Takaaki Ono, Naoto Takahashi, Satoshi Iyama, Makoto Nakamura, Yukinori Nakamura, Koji Izutsu, Nobuhiko Yamauchi, Junichiro Yuda, Yosuke Minami
Journal: Blood
Blood (2021) 138 (Supplement 1): 4464.
https://doi.org/10.1182/blood-2021-148492
Published: 2021
Journal Articles

Hematologic Malignancies (HM)-Screen-Japan 01: A Mutation Profiling Multicenter Study on Patients with Acute Myeloid Leukemia

Naoko Hosono, Takahiro Yamauchi, SungGi Chi, Kentaro Fukushima, Hirohiko Shibayama, Seiichiro Katagiri, Akihiko Gotoh, Motoki Eguchi, Takanobu Morishita, Reiki Ogasawara, Takeshi Kondo, Masamitsu Yanada, Kazuhito Yamamoto, Tsutomu Kobayashi, Junya Kuroda, Kensuke Usuki, Yoshikazu Utsu, Nobuyuki Aotsuka, Makoto Yoshimitsu, Kenji Ishitsuka, Takaaki Ono, Naoto Takahashi, Satoshi Iyama, Makoto Nakamura, Yukinori Nakamura, Suguru Fukuhara, Koji Izutsu, Nobuhiko Yamauchi, Junichiro Yuda, Yosuke Minami
Journal: Blood
Blood (2021) 138 (Supplement 1): 4457.
https://doi.org/10.1182/blood-2021-149960
Published: 2021
Journal Articles

Single-Strand Breaks at Genome Initiate FLT3-ITD Formation

Shota Yokoyama, Masahiro Onozawa, Daisuke Hidaka, Daigo Hashimoto, Masao Nakagawa, Takeshi Kondo, Takanori Teshima
Journal: Blood
Blood (2021) 138 (Supplement 1): 4333.
https://doi.org/10.1182/blood-2021-149451
Published: 2021
Journal Articles

Very Low-Dose Dasatinib Is a Safe and Effective Therapy for Elderly Patients with Newly-Diagnosed Chronic-Phase Chronic Myeloid Leukemia: Results from the Davlec Study, a Single-Arm, Multicenter, Phase 2 Trial

Takashi Kumagai, Kazunori Murai, Hiroshi Ureshino, Hideo Tanaka, Kaichi Nishiwaki, Satoshi Wakita, Koiti Inokuchi, Toshihiro Fukushima, Chikashi Yoshida, Masayuki Mita, Nobuhiko Uoshima, Toru Kiguchi, Jun Aoki, Satoshi Kimura, Kaori Karimata, Kensuke Usuki, Joji Shimono, Yoshiaki Chinen, Junya Kuroda, Yasufumi Matsuda, Kensuke Nakao, Takaaki Ono, Katsumichi Fujimaki, Hirohiko Shibayama, Chisaki Mizumoto, Tomoharu Takeoka, Katsuhiro Io, Takeshi Kondo, Masatomo Miura, Yosuke Minami, Takayuki Ikezoe, Jun Imagawa, Ayako Takamori, Atsushi Kawaguchi, Junichi Sakamoto, Shinya Kimura
Journal: Blood
Blood (2021) 138 (Supplement 1): 3601.
https://doi.org/10.1182/blood-2021-149483
Published: 2021