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Journal Articles

A Phase 1 Trial of OPB-111077 in Combination with Bendamustine (B) and Rituximab (R) in Patients with Relapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL): Preliminary Results of Dose-Escalation Stage

Tomomi Toubai, Junya Kuroda, Youko Suehiro, Yuko Mishima, Kazutaka Sunami, Koji Kato, Nobuhiko Uoshima, Takahiro Kumode, Ai Ota, Kaori Mitsuki, Daisuke Yokota, Yuri Sano, Yasuhito Terui

Blood (2023) 142 (Supplement 1): 4464.

https://doi.org/10.1182/blood-2023-179716

Published: 2023

Journal Articles

Induction of CABLES1 by the TKI Inhibits the Cell Cycle Progression and Induces Apoptosis In CML Cell.

Tomonari Takemura, Satoki Nakamura, Yasuyuki Nagata, Daisuke Yokota, Isao Hirano, Takaaki Ono, Kazuyuki Shigeno, Shinya Fujisawa, Kazunori Ohnishi, MD, PhD

Blood (2010) 116 (21): 1199.

https://doi.org/10.1182/blood.V116.21.1199.1199

Published: 2010

Journal Articles

Bcr-Abl Mediated-Depletion of Dual-Specificity MAP Kinase Phosphatase, DUSP1, Expression Promotes the Cell Proliferation.

Yasuyuki Nagata, Satoki Nakamura, Tomonari Takemura, Daisuke Yokota, Isao Hirano, Takaaki Ono, Kazuyuki Shigeno, Shinya Fujisawa, Kazunori Ohnishi

Blood (2010) 116 (21): 3381.

https://doi.org/10.1182/blood.V116.21.3381.3381

Published: 2010

Journal Articles

Activation of Raf-1 through the Depletion of RKIP by Bcr-Abl Promotes CML Cell Proliferation

Satoki Nakamura, Tomonari Takemura, Yasuyuki Nagata, Daisuke Yokota, Isao Hirano, Takaaki Ono, Kazuyuki Shigeno, Shinya Fujisawa, Kazunori Ohnishi

Blood (2010) 116 (21): 5105.

https://doi.org/10.1182/blood.V116.21.5105.5105

Published: 2010

Journal Articles

Regulation of c-Myc Expression through the Depletion of THAP11 and Fbw7 by Bcr-Abl Promotes CML Cell Proliferation

Daisuke Yokota, Satoki Nakamura, Tomonari Takemura, Yasuyuki Nagata, Isao Hirano, Takaaki Ono, Kazuyuki Shigeno, Shinya Fujisawa, Kazunori Ohnishi

Blood (2010) 116 (21): 4463.

https://doi.org/10.1182/blood.V116.21.4463.4463

Published: 2010

Journal Articles

Downregulation of THAP11 by Bcr-Abl Promotes c-Myc-Mediated CML Cell Proliferation.

Daisuke Yokota, Satoki Nakamura, Tomonari Takemura, Isao Hirano, Shinya Fujisawa, Kaori Takeshita, Takaaki Ono, Kazuyuki Shigeno, Kazunori Ohnishi, MD, PhD

Blood (2009) 114 (22): 3255.

https://doi.org/10.1182/blood.V114.22.3255.3255

Published: 2009

Journal Articles

Identification of Target Molecules and Anti-Leukemic Effects of Novel Phospha Sugar Derivative, TMPP.

Satoki Nakamura, Mitsuji Yamashita, Tomonari Takemura, Daisuke Yokota, Isao Hirano, Takaaki Ono, Kazuyuki Shigeno, Kiyoshi Shibata, Michio Fujie, Shinya Fujisawa, Kaori Shinjo, Kazunori Ohnishi

Blood (2009) 114 (22): 4814.

https://doi.org/10.1182/blood.V114.22.4814.4814

Published: 2009

Journal Articles

Depletion of PHLPP1 and 2 by Bcr-Abl Promotes CML Cell Proliferation through the Continuous Phosphorylation of Akt.

Isao Hirano, Satoki Nakamura, Tomonari Takemura, Daisuke Yokota, Takaaki Ono, Kazuyuki Shigeno, Shinya Fujisawa, Kaori Shinjo, Kazunori Ohnishi

Blood (2009) 114 (22): 2182.

https://doi.org/10.1182/blood.V114.22.2182.2182

Published: 2009

Journal Articles

Bcr-Abl Promotes CML Cell Proliferation through the Suppression of PHLPP Expression.

Isao Hirano, Satoki Nakamura, Daisuke Yokota, Takaaki Ono, Kazuyuki Shigeno, Shinya Fujisawa, Kaori Shinjo, Kazunori Ohnishi, MD, PhD

Blood (2008) 112 (11): 1085.

https://doi.org/10.1182/blood.V112.11.1085.1085

Published: 2008

Journal Articles

Development and Characterization of Phospha Sugar Derivatives, DMPP and TMPP, with Anti-Leukemic Effects

Satoki Nakamura, Mitsuji Yamashita, Daisuke Yokota, Isao Hirano, Takaaki Ono, Michio Fujie, Kiyoshi Shibata, Taishi Niimi, Takuya Suyama, Kasthuraiah Maddali, Kazuhide Asai, Junko Yamashita, Yukiko Iguchi, Kazunori Ohnishi, MD

Blood (2008) 112 (11): 5057.

https://doi.org/10.1182/blood.V112.11.5057.5057

Published: 2008

NARROW

A Phase 1 Trial of OPB-111077 in Combination with Bendamustine (B) and Rituximab (R) in Patients with Relapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL): Preliminary Results of Dose-Escalation Stage

Induction of CABLES1 by the TKI Inhibits the Cell Cycle Progression and Induces Apoptosis In CML Cell.

Bcr-Abl Mediated-Depletion of Dual-Specificity MAP Kinase Phosphatase, DUSP1, Expression Promotes the Cell Proliferation.

Activation of Raf-1 through the Depletion of RKIP by Bcr-Abl Promotes CML Cell Proliferation

Regulation of c-Myc Expression through the Depletion of THAP11 and Fbw7 by Bcr-Abl Promotes CML Cell Proliferation

Downregulation of THAP11 by Bcr-Abl Promotes c-Myc-Mediated CML Cell Proliferation.

Identification of Target Molecules and Anti-Leukemic Effects of Novel Phospha Sugar Derivative, TMPP.

Depletion of PHLPP1 and 2 by Bcr-Abl Promotes CML Cell Proliferation through the Continuous Phosphorylation of Akt.

Bcr-Abl Promotes CML Cell Proliferation through the Suppression of PHLPP Expression.

Development and Characterization of Phospha Sugar Derivatives, DMPP and TMPP, with Anti-Leukemic Effects

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American Society of Hematology

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ASH Publications

American Society of Hematology

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