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Journal Articles

Whole-genome CRISPR screening identifies molecular mechanisms of PD-L1 expression in adult T-cell leukemia/lymphoma

Masahiro Chiba, Joji Shimono, Keito Suto, Takashi Ishio, Tomoyuki Endo, Hideki Goto, Hiroo Hasegawa, Michiyuki Maeda, Takanori Teshima, Yibin Yang, Masao Nakagawa
Journal: Blood
Blood (2024) 143 (14): 1379–1390.
https://doi.org/10.1182/blood.2023021423
Published: 2024
Includes: Supplemental data
Journal Articles

TP53 and CDKN2A alterations Define a Poor Prognostic Subgroup in Patients with Nodal T-Follicular Helper Cell Lymphoma

Yuta Ito, Joji Shimono, Keisuke Kawamoto, Kanako C. Hatanaka, Yasunori Kogure, Junji Koya, Koichi Murakami, Mariko Tabata, Yuki Saito, Mitsuhiro Yuasa, Kota Mizuno, Sara Horie, Yosuke Mizukami, Takanori Teshima, Yutaka Hatanaka, Hiroaki Miyoshi, Yoshihiro Matsuno, Koichi Ohshima, Keisuke Kataoka, Masao Nakagawa
Journal: Blood
Blood (2023) 142 (Supplement 1): 1630.
https://doi.org/10.1182/blood-2023-173638
Published: 2023
Journal Articles

Genome-wide CRISPR screens identify CD48 defining susceptibility to NK cytotoxicity in peripheral T-cell lymphomas

Masahiro Chiba, Joji Shimono, Takashi Ishio, Norio Takei, Kohei Kasahara, Reiki Ogasawara, Takahide Ara, Hideki Goto, Koh Izumiyama, Satoko Otsuguro, Liyanage P. Perera, Hiroo Hasegawa, Michiyuki Maeda, Satoshi Hashino, Katsumi Maenaka, Takanori Teshima, Thomas A. Waldmann, Yibin Yang, Masao Nakagawa
Journal: Blood
Blood (2022) 140 (18): 1951–1963.
https://doi.org/10.1182/blood.2022015646
Published: 2022
Includes: Supplemental data
Journal Articles

Genome-wide CRISPR screen identifies CDK6 as a therapeutic target in adult T-cell leukemia/lymphoma

Takashi Ishio, Sarvesh Kumar, Joji Shimono, Anusara Daenthanasanmak, Sigrid Dubois, Yuquan Lin, Bonita Bryant, Michael N. Petrus, Emmanuel Bachy, Da Wei Huang, Yandan Yang, Patrick L. Green, Hiroo Hasegawa, Michiyuki Maeda, Hideki Goto, Tomoyuki Endo, Takashi Yokota, Kanako C. Hatanaka, Yutaka Hatanaka, Shinya Tanaka, Yoshihiro Matsuno, Yibin Yang, Satoshi Hashino, Takanori Teshima, Thomas A. Waldmann, Louis M. Staudt, Masao Nakagawa
Journal: Blood
Blood (2022) 139 (10): 1541–1556.
https://doi.org/10.1182/blood.2021012734
Published: 2022
Includes: Supplemental data
Journal Articles

Very Low-Dose Dasatinib Is a Safe and Effective Therapy for Elderly Patients with Newly-Diagnosed Chronic-Phase Chronic Myeloid Leukemia: Results from the Davlec Study, a Single-Arm, Multicenter, Phase 2 Trial

Takashi Kumagai, Kazunori Murai, Hiroshi Ureshino, Hideo Tanaka, Kaichi Nishiwaki, Satoshi Wakita, Koiti Inokuchi, Toshihiro Fukushima, Chikashi Yoshida, Masayuki Mita, Nobuhiko Uoshima, Toru Kiguchi, Jun Aoki, Satoshi Kimura, Kaori Karimata, Kensuke Usuki, Joji Shimono, Yoshiaki Chinen, Junya Kuroda, Yasufumi Matsuda, Kensuke Nakao, Takaaki Ono, Katsumichi Fujimaki, Hirohiko Shibayama, Chisaki Mizumoto, Tomoharu Takeoka, Katsuhiro Io, Takeshi Kondo, Masatomo Miura, Yosuke Minami, Takayuki Ikezoe, Jun Imagawa, Ayako Takamori, Atsushi Kawaguchi, Junichi Sakamoto, Shinya Kimura
Journal: Blood
Blood (2021) 138 (Supplement 1): 3601.
https://doi.org/10.1182/blood-2021-149483
Published: 2021
Journal Articles

Genome-Wide CRISPR Library Screening Identifies CDK6 As Genetic Vulnerability in Adult T-Cell Leukemia/Lymphoma

Takashi Ishio, Joji Shimono, Sarvesh Kumar, Yuquan Lin, Emmanuel Bachy, Michael N. Petrus, Yandan Yang, Michiyuki Maeda, Hideki Goto, Satoshi Hashino, Takanori Teshima, MD, Thomas A. Waldmann, MD, Louis Staudt, MD, Masao Nakagawa
Journal: Blood
Blood (2019) 134 (Supplement_1): 3781.
https://doi.org/10.1182/blood-2019-124670
Published: 2019
Journal Articles

Splenic B-Cell Lymphoma/Leukemia, Unclassifiable in Japan

Takaharu Suzuki, MD, Hiroaki Miyoshi, MD PhD, Keisuke Kawamoto, MD PhD, Joji Shimono, MD PhD, Jun Takizawa, MD PhD, Masao Seto, MD PhD, Koichi Ohshima, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5301.
https://doi.org/10.1182/blood-2018-99-113239
Published: 2018
Journal Articles

In Situ Hybridization of HBZ and Tax in FFPE Samples from ATLL Patients and Its Association with Clinicopathological Characteristics

Kyohei Yamada, MD, Hiroaki Miyoshi, MD PhD, Mai Takeuchi, MD PhD, Naoko Asano, MD PhD, Joji Shimono, MD PhD, Fumiko Arakawa, PhD, Kazutaka Nakashima, Kensaku Sato, PhD, Masao Seto, MD PhD, Koichi Ohshima, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1643.
https://doi.org/10.1182/blood-2018-99-112082
Published: 2018
Journal Articles

Clinicopathological Study of Methotrexate-Associated Lymphoproliferative Disorders in Rheumatoid Arthritis Patients: Histological Classification and Predictive Factors for Disease Progression

Daisuke Kurita, MD, Hiroaki Miyoshi, MDPhD, Ayako Ichikawa, MDPhD, Yuya Sasaki, MD, Keisuke Kawamoto, MDPhD, Joji Shimono, MD, Masao Matsuoka, MDPhD, Masahiro Kizaki, MDPhD, Masao Seto, MD PhD, Jun-ichi Tamaru, MDPhD, Michihide Tokuhira, MD, Koichi Ohshima, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4168.
https://doi.org/10.1182/blood.V130.Suppl_1.4168.4168
Published: 2017
Journal Articles

Expression Pattern of Immunosurveillance-Related Antigen Is a Critical Prognostic Factor of Adult T-Cell Leukemia/Lymphoma

Naoko Asano, MD PhD, Hiroaki Miyoshi, MD PhD, Takeharu Kato, MD, Joji Shimono, MD, Noriaki Yoshida, MD PhD, Daisuke Kurita, MD, Yuya Sasaki, MD, Keisuke Kawamoto, MD, Koichi Ohshima, MD PhD, Masao Seto, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4135.
https://doi.org/10.1182/blood.V128.22.4135.4135
Published: 2016
Journal Articles

PD-L1 expression on neoplastic or stromal cells is respectively a poor or good prognostic factor for adult T-cell leukemia/lymphoma

Clinical Trials & Observations
Hiroaki Miyoshi, Junichi Kiyasu, Takeharu Kato, Noriaki Yoshida, Joji Shimono, Shintaro Yokoyama, Hiroaki Taniguchi, Yuya Sasaki, Daisuke Kurita, Keisuke Kawamoto, Koji Kato, Yoshitaka Imaizumi, Masao Seto, Koichi Ohshima
Journal: Blood
Blood (2016) 128 (10): 1374–1381.
https://doi.org/10.1182/blood-2016-02-698936
Published: 2016