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Journal Articles

Whole-genome CRISPR screening identifies molecular mechanisms of PD-L1 expression in adult T-cell leukemia/lymphoma

Masahiro Chiba, Joji Shimono, Keito Suto, Takashi Ishio, Tomoyuki Endo, Hideki Goto, Hiroo Hasegawa, Michiyuki Maeda, Takanori Teshima, Yibin Yang, Masao Nakagawa

Blood (2024) 143 (14): 1379–1390.

https://doi.org/10.1182/blood.2023021423

Published: 2024

Includes: Supplemental data

Journal Articles

Genome-wide CRISPR screens identify CD48 defining susceptibility to NK cytotoxicity in peripheral T-cell lymphomas

Masahiro Chiba, Joji Shimono, Takashi Ishio, Norio Takei, Kohei Kasahara, Reiki Ogasawara, Takahide Ara, Hideki Goto, Koh Izumiyama, Satoko Otsuguro, Liyanage P. Perera, Hiroo Hasegawa, Michiyuki Maeda, Satoshi Hashino, Katsumi Maenaka, Takanori Teshima, Thomas A. Waldmann, Yibin Yang, Masao Nakagawa

Blood (2022) 140 (18): 1951–1963.

https://doi.org/10.1182/blood.2022015646

Published: 2022

Includes: Supplemental data

Journal Articles

Genome-wide CRISPR screen identifies CDK6 as a therapeutic target in adult T-cell leukemia/lymphoma

Blood (2022) 139 (10): 1541–1556.

https://doi.org/10.1182/blood.2021012734

Published: 2022

Includes: Supplemental data

Journal Articles

Heat Shock Protein 90 Inhibitor NVP-AUY922 Has Potent Anti-Tumor Activity With Adult T-Cell Leukemia-Lymphoma Cells

Hiroaki Taniguchi, MD, Hiroo Hasegawa, MD, PhD, Daisuke Sasaki, PhD, Koji Ando, MD, PhD, Yasushi Sawayama, MD, PhD, Yoshitaka Imaizumi, MD, PhD, Daisuke Imanishi, MD, PhD, Jun Taguchi, MD, PhD, Tomoko Hata, MD, PhD, Kunihiro Tsukasaki, MD, PhD, Katsunori Yanagihara, MD, PhD, Naoki Mori, MD, PhD, Yasushi Miyazaki, MD, PhD

Blood (2013) 122 (21): 1829.

https://doi.org/10.1182/blood.V122.21.1829.1829

Published: 2013

Journal Articles

Transient proliferation of donor-derived ATL cell–like lymphocytes early after allogeneic stem cell transplantation in an adult T-cell leukemia/lymphoma patient

Masataka Taguchi, Yoshitaka Imaizumi, Jun Taguchi, Daisuke Imanishi, Daisuke Sasaki, Hiroo Hasegawa, Hideki Tsushima, Tomoko Hata, Yasushi Miyazaki

Blood (2013) 121 (21): 4428–4430.

https://doi.org/10.1182/blood-2013-02-487652

Published: 2013

Journal Articles

The Overexpression of Enhancer of Zeste Homologue 2 Is Associated with Tumor Proliferation and Aggressive Behavior in Adult T-Cell Leukemia/Lymphoma.

Daisuke Sasaki, Yoshitaka Imaizumi, Hiroo Hasegawa, Akemi Osaka, Kazuto Tsuruda, Kunihiro Tsukasaki, Masako Iwanaga, Yasushi Miyazaki, Katsunori Yanagihara, Victor Marquez, Shimeru Kamihira, Yasuaki Yamada

Blood (2009) 114 (22): 3959.

https://doi.org/10.1182/blood.V114.22.3959.3959

Published: 2009

Journal Articles

Trends in Human T-Cell Leukemia Virus Type-1 (HTLV-1) Prevalence and the Incidence of Adult T-Cell Leukemia/Lymphoma (ATL) in Nagasaki, Japan: A Hospital-Based and Population-Based Study.

Masako Iwanaga, Yoshito Koga, Midori Soda, Naoko Inokuchi, Daisuke Sasaki, Hiroo Hasegawa, Katsunori Yanagihara, Kazunari Yamaguchi, Shimeru Kamihira, Yasuaki Yamada

Blood (2009) 114 (22): 1920.

https://doi.org/10.1182/blood.V114.22.1920.1920

Published: 2009

Journal Articles

Frequent Expression of MUC1, a Membrane-Associated Mucin, in Adult T-Cell Leukemia Cells.

Hiroo Hasegawa, Minori Komoda, Yasuaki Yamada, Suguru Yonezawa, Yasushi Miyazaki, Kunihiro Tsukasaki, Kazuhiro Nagai, Sunao Atogami, Akemi Osaka, Daisuke Sasaki, Kazuto Tsuruda, Shimeru Kamihira

Blood (2009) 114 (22): 1922.

https://doi.org/10.1182/blood.V114.22.1922.1922

Published: 2009

Journal Articles

A novel natural compound, a cycloanthranilylproline derivative (Fuligocandin B), sensitizes leukemia cells to apoptosis induced by tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) through 15-deoxy-Δ 12, 14 prostaglandin J 2 production

Hiroo Hasegawa, Yasuaki Yamada, Kanki Komiyama, Masahiko Hayashi, Masami Ishibashi, Toshiaki Sunazuka, Takeshi Izuhara, Kazuyuki Sugahara, Kazuto Tsuruda, Masato Masuda, Nobuyuki Takasu, Kunihiro Tsukasaki, Masao Tomonaga, Shimeru Kamihira

Blood (2007) 110 (5): 1664–1674.

https://doi.org/10.1182/blood-2007-01-068981

Published: 2007

Journal Articles

Nutlin-3a, an MDM2 Antagonist, Induces Cellular Senescence in Adult T-Cell Leukemia/Lymphoma Cells.

Hiroo Hasegawa, MD, PhD, Yasuaki Yamada, MD,phD, Akiko Uemura, Kazuyuki Sugahara, PhD, Kazuto Tsuruda, Norihiko Akamatsu, student, Masato Masuda, MD,phD, Nobuyuki Takasu, MD,phD, Kunihiro Tsukasaki, MD,phD, Shimeru Kamihira, MD,phD

Blood (2006) 108 (11): 2515.

https://doi.org/10.1182/blood.V108.11.2515.2515

Published: 2006

Journal Articles

Serum Cytochrome C as a Tumor Marker in Leukemia and Lymphoma.

Akemi Osaka, Takashi Sawada, PhD, Yasuaki Yamada, MD, Muneo Aoyama, Hiroo Hasegawa, MD, Daisuke Sasaki, MT, Kazuto Tsuruda, MT, Naoko Inokuchi, MT, Shimeru Kamihira, MD

Blood (2006) 108 (11): 4435.

https://doi.org/10.1182/blood.V108.11.4435.4435

Published: 2006

Journal Articles

Dihydroflavonol BB-1, an extract of natural plant Blumea balsamifera , abrogates TRAIL resistance in leukemia cells

Hiroo Hasegawa, Yasuaki Yamada, Kanki Komiyama, Masahiko Hayashi, Masami Ishibashi, Tatsushi Yoshida, Toshiyuki Sakai, Takashi Koyano, Toh-Seok Kam, Ken Murata, Kazuyuki Sugahara, Kazuto Tsuruda, Norihiko Akamatsu, Kunihiro Tsukasaki, Masato Masuda, Nobuyuki Takasu, Shimeru Kamihira

Blood (2006) 107 (2): 679–688.

https://doi.org/10.1182/blood-2005-05-1982

Published: 2006

Journal Articles

Selected IL-21R Expression and Apoptosis Induction by IL-21 in Follicular Lymphoma.

Norihiko Akamatsu, Hiroo Hasegawa, MD, Yasuaki Yamada, MD, Koki Makabe, PhD, Ryutaro Asano, PhD, Izumi Kumagai, PhD, Ken Murata, MD, Kunihiro Tsukasaki, MD, Masao Tomonaga, MD, Kazuto Tsuruda, MT, Kazuyuki Sugahara, MT, Shimeru Kamihira, MD

Blood (2004) 104 (11): 2284.

https://doi.org/10.1182/blood.V104.11.2284.2284

Published: 2004

Journal Articles

Dihydroflavonol BB-1, an Extract of Natural Plant Blumea Balsamifera , Abrogates TRAIL Resistance in Adult T-Cell Leukemia/Lymphoma.

Hiroo Hasegawa, MD, Yasuaki Yamada, MD, phD, Masahiko Hayashi, phD, Masami Ishibashi, phD, Kanki Komiyama, phD, Ken Murata, MD, phD, Masato Masuda, MD, phD, Nobuyuki Takasu, MD, phD, Masao Tomonaga, MD, phD, Shimeru Kamihira, MD, phD

Blood (2004) 104 (11): 2290.

https://doi.org/10.1182/blood.V104.11.2290.2290

Published: 2004

NARROW

Whole-genome CRISPR screening identifies molecular mechanisms of PD-L1 expression in adult T-cell leukemia/lymphoma

Genome-wide CRISPR screens identify CD48 defining susceptibility to NK cytotoxicity in peripheral T-cell lymphomas

Genome-wide CRISPR screen identifies CDK6 as a therapeutic target in adult T-cell leukemia/lymphoma

Heat Shock Protein 90 Inhibitor NVP-AUY922 Has Potent Anti-Tumor Activity With Adult T-Cell Leukemia-Lymphoma Cells

Transient proliferation of donor-derived ATL cell–like lymphocytes early after allogeneic stem cell transplantation in an adult T-cell leukemia/lymphoma patient

The Overexpression of Enhancer of Zeste Homologue 2 Is Associated with Tumor Proliferation and Aggressive Behavior in Adult T-Cell Leukemia/Lymphoma.

Trends in Human T-Cell Leukemia Virus Type-1 (HTLV-1) Prevalence and the Incidence of Adult T-Cell Leukemia/Lymphoma (ATL) in Nagasaki, Japan: A Hospital-Based and Population-Based Study.

Frequent Expression of MUC1, a Membrane-Associated Mucin, in Adult T-Cell Leukemia Cells.

A novel natural compound, a cycloanthranilylproline derivative (Fuligocandin B), sensitizes leukemia cells to apoptosis induced by tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) through 15-deoxy-Δ 12, 14 prostaglandin J 2 production

Nutlin-3a, an MDM2 Antagonist, Induces Cellular Senescence in Adult T-Cell Leukemia/Lymphoma Cells.

Serum Cytochrome C as a Tumor Marker in Leukemia and Lymphoma.

Dihydroflavonol BB-1, an extract of natural plant Blumea balsamifera , abrogates TRAIL resistance in leukemia cells

Selected IL-21R Expression and Apoptosis Induction by IL-21 in Follicular Lymphoma.

Dihydroflavonol BB-1, an Extract of Natural Plant Blumea Balsamifera , Abrogates TRAIL Resistance in Adult T-Cell Leukemia/Lymphoma.

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American Society of Hematology

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American Society of Hematology

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