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Niklas Beumer
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Journal Articles

AML Treatment By the AXL Inhibitor Bemcentinib in Combination with Cytarabine Shows Clinical Efficacy Related to TNFα and Cytotoxic Immune Cells: A Single-Cell Translational Study from the BGBC003 Trial

Niklas Beumer, Jonas S. Waizenegger, Michael Heuser, Jörg Chromik, Grerk Sutamtewagul, Silke Kapp-Schwoerer, Monica Crugnola, Nicola Di Renzo, Roberto M. Lemoli, Daniele G. Mattei, Walter Fiedler, Yesid Alvarado-Valero, David Micklem, Linn H. Nilsson, Noelly Madeleine, Nigel McCracken, Cristina Oliva, Claudia Gorcea-Carson, Lisa-Marie Rieckmann, Jenny Krause, Victoria Gensch, Isabel Ben Batalla, Melanie Janning, Nicola Gagliani, Benedikt Brors, Charles D. Imbusch, Bjorn T. Gjertsen, Sonja Loges
Journal: Blood
Blood (2023) 142 (Supplement 1): 1540.
https://doi.org/10.1182/blood-2023-185499
Published: 2023
Journal Articles

Phase Ib/II Study (NCT02488408 / BGBC003) of Bemcentinib Monotherapy or in Combination with Cytarabine or Decitabine in Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS): FINAL Results

Sonja Loges, Michael Heuser, Jolanta Chromik, Grerk Sutamtewagul, Silke Kapp-Schwoerer, Monica Crugnola, Nicola Di Renzo, Roberto Massimo Lemoli, Daniele Giovanni Mattei, Isabel Ben Batalla, Jonas Waizenegger, Melanie Janning, Lisa-Marie Rieckmann, Charles Imbusch, Niklas Beumer, David Micklam, Claudia Gorcea-Carson, Cristina Oliva, Walter Fiedler, Yesid Alvarado-Valero, Nigel McCracken, Bjorn T. Gjertsen
Journal: Blood
Blood (2023) 142 (Supplement 1): 4287.
https://doi.org/10.1182/blood-2023-181833
Published: 2023
Journal Articles

Bemcentinib (Oral AXL Inhibitor) in Combination with Low-Dose Cytarabine Is Well Tolerated and Efficacious in Older Relapsed AML Patients.Updates from the Ongoing Phase II Trial (NCT02488408) and Preliminary Translational Results Indicating Bemcentinib Elicits Anti-AML Immune Responses

Sonja Loges, Grerk Sutamtewagul, Michael Heuser, Jörg Chromik, Silke Kapp-Schwoerer, Monica Crugnola, Nicola Di Renzo, Roberto M. Lemoli, Daniele Giovanni Mattei, Isabel Ben Batalla, Monica Hellesøy, Jonas Waizenegger, Melanie Janning, Charles D. Imbusch, Niklas Beumer, Austin Rayford, Jaya Nautiyal, Tzivia Berkman-Gottlieb, David Micklem, Hani Gabra, Claudia Gorcea-Carson, James B. Lorens, Walter Fiedler, Yesid Alvarado, Bjorn T. Gjertsen, Lisa-Marie Rieckmann
Journal: Blood
Blood (2021) 138 (Supplement 1): 3410.
https://doi.org/10.1182/blood-2021-147225
Published: 2021