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Journal Articles

Kinase-inactivated CDK6 preserves the long-term functionality of adult hematopoietic stem cells

Blood (2024) 144 (2): 156–170.

https://doi.org/10.1182/blood.2023021985

Published: 2024

Includes: Supplemental data

Journal Articles

A lineage-specific STAT5B N642H mouse model to study NK-cell leukemia

Klara Klein, Sebastian Kollmann, Angela Hiesinger, Julia List, Jonatan Kendler, Thorsten Klampfl, Mehak Rhandawa, Jana Trifinopoulos, Barbara Maurer, Reinhard Grausenburger, Christof A. Betram, Richard Moriggl, Thomas Rülicke, Charles G. Mullighan, Agnieszka Witalisz-Siepracka, Wencke Walter, Gregor Hoermann, Veronika Sexl, Dagmar Gotthardt

Blood (2024) 143 (24): 2474–2489.

https://doi.org/10.1182/blood.2023022655

Published: 2024

Includes: Supplemental data

Journal Articles

Tumor necrosis factor α promotes clonal dominance of KIT D816V + cells in mastocytosis: role of survivin and impact on prognosis

Blood (2024) 143 (11): 1006–1017.

https://doi.org/10.1182/blood.2023020515

Published: 2024

Includes: Supplemental data

Journal Articles

SBNO2 is a critical mediator of STAT3-driven hematological malignancies

Tania Brandstoetter, Johannes Schmoellerl, Reinhard Grausenburger, Sebastian Kollmann, Eszter Doma, Jani Huuhtanen, Thorsten Klampfl, Thomas Eder, Florian Grebien, Gregor Hoermann, Johannes Zuber, Satu Mustjoki, Barbara Maurer, Veronika Sexl

Blood (2023) 141 (15): 1831–1845.

https://doi.org/10.1182/blood.2022018494

Published: 2023

Includes: Supplemental data

Journal Articles

STAT1 and MHCII: guardians of stressed HSCs

Sebastian Kollmann, Veronika Sexl

Blood (2022) 140 (14): 1575–1576.

https://doi.org/10.1182/blood.2022016850

Published: 2022

Journal Articles

A STAT5B–CD9 axis determines self-renewal in hematopoietic and leukemic stem cells

Sebastian Kollmann, Reinhard Grausenburger, Thorsten Klampfl, Michaela Prchal-Murphy, Klavdija Bastl, Hanja Pisa, Vanessa M. Knab, Tania Brandstoetter, Eszter Doma, Wolfgang R. Sperr, Sabine Lagger, Matthias Farlik, Richard Moriggl, Peter Valent, Florian Halbritter, Karoline Kollmann, Gerwin Heller, Barbara Maurer, Veronika Sexl

Blood (2021) 138 (23): 2347–2359.

https://doi.org/10.1182/blood.2021010980

Published: 2021

Includes: Supplemental data

Journal Articles

CDK6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemia

Blood (2020) 136 (4): 387–400.

https://doi.org/10.1182/blood.2019003267

Published: 2020

Includes: Supplemental data

Journal Articles

BCR-ABL1 p190 in CML: A Minor Breakpoint with a Major Impact

Shady Adnan Awad, MD, Helena Hohtari, MD, Komal Kumar Javarappa, PhD, Tania Brandstoetter, Daehong Kim, Swapnil Potdar, MSc, Caroline A Heckman, PhD, Soili Kytölä, PhD, Kimmo Porkka, Eszter Doma, PhD, Veronika Sexl, MD PhD, Matti Kankainen, PhD, Satu Mustjoki, MD PhD

Blood (2019) 134 (Supplement_1): 190.

https://doi.org/10.1182/blood-2019-126584

Published: 2019

Journal Articles

CDK6 Antagonizes TP53-Induced Responses during Tumorigenesis

Veronika Sexl, MD PhD, Karoline Kollmann, PhD, Florian Bellutti

Blood (2019) 134 (Supplement_1): SCI-15.

https://doi.org/10.1182/blood-2019-121101

Published: 2019

Journal Articles

CDK6 coordinates JAK2 V617F mutant MPN via NF-κB and apoptotic networks

Iris Z. Uras, Barbara Maurer, Harini Nivarthi, Philipp Jodl, Karoline Kollmann, Michaela Prchal-Murphy, Jelena D. Milosevic Feenstra, Markus Zojer, Sabine Lagger, Reinhard Grausenburger, Beatrice Grabner, Raimund Holly, Anoop Kavirayani, Christoph Bock, Heinz Gisslinger, Peter Valent, Robert Kralovics, Veronika Sexl

Blood (2019) 133 (15): 1677–1690.

https://doi.org/10.1182/blood-2018-08-872648

Published: 2019

Includes: Supplemental data

Journal Articles

Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy

Blood (2018) 132 (7): 694–706.

https://doi.org/10.1182/blood-2017-10-810739

Published: 2018

Includes: Supplemental data

Journal Articles

JAK2-Inhibitor Therapy Associated Lymphomas in Myelofibrosis: Distinct Clinico-Pathological Features Recapitulated in a Mouse Model

Blood (2017) 130 (Supplement 1): 1643.

https://doi.org/10.1182/blood.V130.Suppl_1.1643.1643

Published: 2017

Journal Articles

CCL2 is a KIT D816V–dependent modulator of the bone marrow microenvironment in systemic mastocytosis

Georg Greiner, Nadine Witzeneder, Angelika Berger, Klaus Schmetterer, Gregor Eisenwort, Ana-Iris Schiefer, Simone Roos, Theresia Popow-Kraupp, Leonhard Müllauer, Johannes Zuber, Veronika Sexl, Lukas Kenner, Wolfgang R. Sperr, Peter Valent, Matthias Mayerhofer, Gregor Hoermann

Blood (2017) 129 (3): 371–382.

https://doi.org/10.1182/blood-2016-09-739003

Published: 2017

Includes: Supplemental data

Journal Articles

Palbociclib treatment of FLT3 -ITD + AML cells uncovers a kinase-dependent transcriptional regulation of FLT3 and PIM1 by CDK6

Iris Z. Uras, Gina J. Walter, Ruth Scheicher, Florian Bellutti, Michaela Prchal-Murphy, Anca S. Tigan, Peter Valent, Florian H. Heidel, Stefan Kubicek, Claudia Scholl, Stefan Fröhling, Veronika Sexl

Blood (2016) 127 (23): 2890–2902.

https://doi.org/10.1182/blood-2015-11-683581

Published: 2016

Includes: Supplemental data

Journal Articles

CDK6 as a key regulator of hematopoietic and leukemic stem cell activation

Ruth Scheicher, Andrea Hoelbl-Kovacic, Florian Bellutti, Anca-Sarmiza Tigan, Michaela Prchal-Murphy, Gerwin Heller, Christine Schneckenleithner, María Salazar-Roa, Sabine Zöchbauer-Müller, Johannes Zuber, Marcos Malumbres, Karoline Kollmann, Veronika Sexl

Blood (2015) 125 (1): 90–101.

https://doi.org/10.1182/blood-2014-06-584417

Published: 2015

Includes: Supplemental data

Journal Articles

Loss of STAT3 in murine NK cells enhances NK cell–dependent tumor surveillance

Dagmar Gotthardt, Eva M. Putz, Elisabeth Straka, Petra Kudweis, Mario Biaggio, Valeria Poli, Birgit Strobl, Mathias Müller, Veronika Sexl

Blood (2014) 124 (15): 2370–2379.

https://doi.org/10.1182/blood-2014-03-564450

Published: 2014

Includes: Supplemental data

Journal Articles

Cdk4 and Cdk6 cooperate in counteracting the INK4 family of inhibitors during murine leukemogenesis

Esther Rodríguez-Díez, Victor Quereda, Florian Bellutti, Michaela Prchal-Murphy, David Partida, Manuel Eguren, Karoline Kollmann, Marta Gómez de Cedrón, Pierre Dubus, Marta Cañamero, Dolores Martínez, Veronika Sexl, Marcos Malumbres

Blood (2014) 124 (15): 2380–2390.

https://doi.org/10.1182/blood-2014-02-555292

Published: 2014

Includes: Supplemental data

Journal Articles

Mir-15/16 Antagonizes Myb To Control Natural Killer Cell Differentiation and Maturation

Ryan P Sullivan, Jeffrey W Leong, Stephanie E Schneider, Rizwan Romee, MD, Veronika Sexl, MD, Riccardo Dalla-Favera, MD, Todd A. Fehniger, MD, PhD

Blood (2013) 122 (21): 17.

https://doi.org/10.1182/blood.V122.21.17.17

Published: 2013

Journal Articles

The Oncogenic Transcription Factor STAT5 Triggers Aberrant Expression Of CD25 (IL-2RA) In Neoplastic Stem Cells In Ph + CML

Irina Sadovnik, M.Sc., Harald Herrmann, M.D., Sabine Cerny-Reiterer, D.V.M, Wolfgang Warsch, Ph.D., Andrea Hoelbl, Ph.D., Katharina Blatt, MSc, Ph.D., Barbara Peter, D.V.M., Gabriele Stefanzl, Msc, Gregor Hoermann, M.D., Ph.D., Susanne Herndlhofer, Berthold Streubel, M.D., Wolfgang R Sperr, M.D., Christine Mannhalter, Ph.D., Veronika Sexl, MD, Peter Valent

Blood (2013) 122 (21): 3979.

https://doi.org/10.1182/blood.V122.21.3979.3979

Published: 2013

Journal Articles

JAK of all trades: JAK2-STAT5 as novel therapeutic targets in BCR-ABL1 + chronic myeloid leukemia

Wolfgang Warsch, Christoph Walz, Veronika Sexl

Blood (2013) 122 (13): 2167–2175.

https://doi.org/10.1182/blood-2013-02-485573

Published: 2013

NARROW

Kinase-inactivated CDK6 preserves the long-term functionality of adult hematopoietic stem cells

A lineage-specific STAT5B N642H mouse model to study NK-cell leukemia

Tumor necrosis factor α promotes clonal dominance of KIT D816V + cells in mastocytosis: role of survivin and impact on prognosis

SBNO2 is a critical mediator of STAT3-driven hematological malignancies

STAT1 and MHCII: guardians of stressed HSCs

A STAT5B–CD9 axis determines self-renewal in hematopoietic and leukemic stem cells

CDK6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemia

BCR-ABL1 p190 in CML: A Minor Breakpoint with a Major Impact

CDK6 Antagonizes TP53-Induced Responses during Tumorigenesis

CDK6 coordinates JAK2 V617F mutant MPN via NF-κB and apoptotic networks

Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy

JAK2-Inhibitor Therapy Associated Lymphomas in Myelofibrosis: Distinct Clinico-Pathological Features Recapitulated in a Mouse Model

CCL2 is a KIT D816V–dependent modulator of the bone marrow microenvironment in systemic mastocytosis

Palbociclib treatment of FLT3 -ITD + AML cells uncovers a kinase-dependent transcriptional regulation of FLT3 and PIM1 by CDK6

CDK6 as a key regulator of hematopoietic and leukemic stem cell activation

Loss of STAT3 in murine NK cells enhances NK cell–dependent tumor surveillance

Cdk4 and Cdk6 cooperate in counteracting the INK4 family of inhibitors during murine leukemogenesis

Mir-15/16 Antagonizes Myb To Control Natural Killer Cell Differentiation and Maturation

The Oncogenic Transcription Factor STAT5 Triggers Aberrant Expression Of CD25 (IL-2RA) In Neoplastic Stem Cells In Ph + CML

JAK of all trades: JAK2-STAT5 as novel therapeutic targets in BCR-ABL1 + chronic myeloid leukemia

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American Society of Hematology

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American Society of Hematology

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