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Georg Greiner
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Journal Articles

Tumor necrosis factor α promotes clonal dominance of KIT D816V + cells in mastocytosis: role of survivin and impact on prognosis

Georg Greiner, Nadine Witzeneder, Klara Klein, Simone Tangermann, Petra Kodajova, Eva Jaeger, Franz Ratzinger, Marlene C. Gerner, Mohamad Jawhar, Sigrid Baumgartner, Karin Fruehwirth, Klaus G. Schmetterer, Johannes Zuber, Karoline V. Gleixner, Matthias Mayerhofer, Ilse Schwarzinger, Ingrid Simonitsch-Klupp, Harald Esterbauer, Constance Baer, Wencke Walter, Manja Meggendorfer, Robert Strassl, Torsten Haferlach, Karin Hartmann, Lukas Kenner, Wolfgang R. Sperr, Andreas Reiter, Veronika Sexl, Michel Arock, Peter Valent, Gregor Hoermann
Journal: Blood
Blood (2024) 143 (11): 1006–1017.
https://doi.org/10.1182/blood.2023020515
Published: 2024
Includes: Supplemental data
Journal Articles

Delineation of Predictive Features of AML Patients with Recurrent Relapse Who Achieved Repeated Complete Remission after Multiple Re-Induction and Consolidation Therapies

Irene Graf, Georg Greiner, Karoline V. Gleixner, Susanne Herndlhofer, Gabriele Stefanzl, Paul Knöbl, Alexander Hauswirth, Manja Meggendorfer, Ulrich Jaeger, Constance Baer, Torsten Haferlach, Gregor Hoermann, Peter Valent, Wolfgang R. Sperr
Journal: Blood
Blood (2022) 140 (Supplement 1): 11634–11635.
https://doi.org/10.1182/blood-2022-162588
Published: 2022
Journal Articles

NT-Probnp As Personalized Medicine Tool and New Biomarker Predicting Response to Chemotherapy and Survival in AML

Irene Graf, Georg Greiner, Rodrig Marculescu, Karoline V. Gleixner, Susanne Herndlhofer, Gabriele Stefanzl, Paul Knoebl, Ulrich Jaeger, Alexander Hauswirth, Ilse Schwarzinger, Renate Thalhammer, Michael Kundi, Gregor Hoermann, Gerlinde Mitterbauer-Hohendanner, Peter Valent, Wolfgang R. Sperr
Journal: Blood
Blood (2021) 138 (Supplement 1): 3435.
https://doi.org/10.1182/blood-2021-149526
Published: 2021
Journal Articles

Deciphering the Mechanisms of Osteoblast-Induced Resistance of Leukemic Stem Cell (LSC) in Ph+ CML: Role of PI3-Kinase, BRD4 and MYC and Development of Strategies to Overcome Osteoblast-Induced Resistance

Yueksel Filik, Karin Bauer, Barbara Peter, Emir Hadzijusufovic, Georg Greiner, Nadine Witzeneder, Gregor Hoermann, Karoline V. Gleixner, Wolfgang R. Sperr, Peter Valent
Journal: Blood
Blood (2021) 138 (Supplement 1): 1481.
https://doi.org/10.1182/blood-2021-152415
Published: 2021
Journal Articles

Hereditary α tryptasemia is a valid genetic biomarker for severe mediator-related symptoms in mastocytosis

Clinical Trials & Observations
Georg Greiner, Bettina Sprinzl, Aleksandra Górska, Franz Ratzinger, Michael Gurbisz, Nadine Witzeneder, Klaus G. Schmetterer, Bettina Gisslinger, Goekhan Uyanik, Emir Hadzijusufovic, Harald Esterbauer, Karoline V. Gleixner, Maria T. Krauth, Michael Pfeilstöcker, Felix Keil, Heinz Gisslinger, Boguslaw Nedoszytko, Marek Niedoszytko, Wolfgang R. Sperr, Peter Valent, Gregor Hoermann
Journal: Blood
Blood (2021) 137 (2): 238–247.
https://doi.org/10.1182/blood.2020006157
Published: 2021
Includes: Supplemental data
Journal Articles

TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors

Silvia Maifrede, Bac Viet Le, Margaret Nieborowska-Skorska, Konstantin Golovine, Katherine Sullivan-Reed, Wangisa M.B. Dunuwille, Joseph Nacson, Michael Hulse, Lisa Beatrice Caruso, Zachary Gazze, Zhaorui Lian, Antonella Padella, Kumaraswamy Chitrala, Boris Bartholdy, Ksenia Matlawska-Wasowska, Daniela Di Marcantonio, Giorgia Simonetti, Georg Greiner, Stephen M. Sykes, Peter Valent, MD, Elisabeth M. Paietta, Hugo F Fernandez, Martin S. Tallman, MD, Mark Litzow, MD, Mark D. Minden, Jian Huang, Giovanni Martinelli, MD, George S. Vassiliou, MD PhD FRCPath, MRCP, Italo Tempera, Katarzyna Piwocka, Neil Johnson, Grant Challen, Tomasz Skorski, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 4.
https://doi.org/10.1182/blood-2020-137658
Published: 2020
Journal Articles

Phenotyping of Disease-Initiating CD34 + /CD38 ─ Stem Cells in BCR-ABL1 ─ MPN Reveals Expression of Multiple Cytokine Receptors and Resistance-Related Antigens

Daniel Ivanov, MSc, Jelena D. Milosevic Feenstra, PhD, Gregor Eisenwort, MD PhD, Robert Spörk, MSc, Alexandra Keller, PhD, Barbara Peter, Michael Willmann, Georg Greiner, Gabriele Stefanzl, Katharina Slavnitsch, Gregor Hoermann, Sybille Hofer, Wolfgang R. Sperr, MD, Heinz Sill, MD, Peter Bettelheim, MD, Klaus Geissler, MD, Elisabeth Koller, Michael Fillitz, MD, Michael Pfeilstocker, MD, Thomas Rülicke, Thamer Sliwa, MD, Felix Keil, MD, Robert Kralovics, PhD, Peter Valent, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 53.
https://doi.org/10.1182/blood-2020-140477
Published: 2020
Journal Articles

CD44 is a RAS/STAT5-regulated invasion receptor that triggers disease expansion in advanced mastocytosis

Niklas Mueller, Daniel Wicklein, Gregor Eisenwort, Mohamad Jawhar, Daniela Berger, Gabriele Stefanzl, Georg Greiner, Alexandra Boehm, Christoph Kornauth, Leonhard Muellauer, Susanne Sehner, Gregor Hoermann, Wolfgang R. Sperr, Philipp B. Staber, Ulrich Jaeger, Johannes Zuber, Michel Arock, Udo Schumacher, Andreas Reiter, Peter Valent
Journal: Blood
Blood (2018) 132 (18): 1936–1950.
https://doi.org/10.1182/blood-2018-02-833582
Published: 2018
Includes: Supplemental data
Journal Articles

Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy

Clinical Trials & Observations
Edit Porpaczy, Sabrina Tripolt, Andrea Hoelbl-Kovacic, Bettina Gisslinger, Zsuzsanna Bago-Horvath, Emilio Casanova-Hevia, Emmanuelle Clappier, Thomas Decker, Sabine Fajmann, Daniela A. Fux, Georg Greiner, Sinan Gueltekin, Gerwin Heller, Harald Herkner, Gregor Hoermann, Jean-Jacques Kiladjian, Thomas Kolbe, Christoph Kornauth, Maria-Theresa Krauth, Robert Kralovics, Leonhard Muellauer, Mathias Mueller, Michaela Prchal-Murphy, Eva Maria Putz, Emmanuel Raffoux, Ana-Iris Schiefer, Klaus Schmetterer, Christine Schneckenleithner, Ingrid Simonitsch-Klupp, Cathrin Skrabs, Wolfgang R. Sperr, Philipp Bernhard Staber, Birgit Strobl, Peter Valent, Ulrich Jaeger, Heinz Gisslinger, Veronika Sexl
Journal: Blood
Blood (2018) 132 (7): 694–706.
https://doi.org/10.1182/blood-2017-10-810739
Published: 2018
Includes: Supplemental data
Journal Articles

CCL2 is a KIT D816V–dependent modulator of the bone marrow microenvironment in systemic mastocytosis

Georg Greiner, Nadine Witzeneder, Angelika Berger, Klaus Schmetterer, Gregor Eisenwort, Ana-Iris Schiefer, Simone Roos, Theresia Popow-Kraupp, Leonhard Müllauer, Johannes Zuber, Veronika Sexl, Lukas Kenner, Wolfgang R. Sperr, Peter Valent, Matthias Mayerhofer, Gregor Hoermann
Journal: Blood
Blood (2017) 129 (3): 371–382.
https://doi.org/10.1182/blood-2016-09-739003
Published: 2017
Includes: Supplemental data
Journal Articles

Combined Targeting of STAT3 and STAT5: A Novel Approach to Overcome Drug Resistance in Ph + Cml

Karoline V Gleixner, MD, Mathias A Schneeweiss, MD, Harald Herrmann, MD, Katharina Blatt, MSc, PhD, Daniela Berger, Gregor Eisenwort, MD PhD, Georg Greiner, MD, Konstantin Byrgazov, PhD, Gregor Hoermann, Marina Konopleva, MD PhD, Islam Waliul, Patrick T Gunning, PhD, Hiroshi Maeda, PhD, Richard Moriggl, PhD, Michael W. Deininger, MD PhD, Thomas Lion, PhD, Michael Andreeff, MD PhD, Peter Valent, MD
Journal: Blood
Blood (2016) 128 (22): 4241.
https://doi.org/10.1182/blood.V128.22.4241.4241
Published: 2016
Journal Articles

CCL-2 Is a KIT D816V-Dependent Modulator of Bone Marrow Remodeling and Microenvironmental Alterations in Systemic Mastocytosis

Georg Greiner, MD, Nadine Witzeneder, Klaus Schmetterer, MD PhD, Theresia Popow-Kraupp, MD, Wolfgang R Sperr, MD, Peter Valent, MD, Matthias Mayerhofer, MD, Gregor Hoermann, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1635.
https://doi.org/10.1182/blood.V126.23.1635.1635
Published: 2015
Journal Articles

KIT D816V Mutation Burden Predicts Prognosis and Survival In Patients With Mastocytosis and Correlates With The WHO Type Of The Disease

Gregor Hoermann, M.D., Ph.D., Karoline V. Gleixner, M.D., Graziella E. Dinu, B.Sc., Georg Greiner, Friedrich Wimazal, M.D., Emir Hadzijusufovic, DVM, Gerlinde Mitterbauer, M.D., Christine Mannhalter, Ph.D., Peter Valent, Wolfgang R Sperr, M.D.
Journal: Blood
Blood (2013) 122 (21): 4052.
https://doi.org/10.1182/blood.V122.21.4052.4052
Published: 2013