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Philipp Bernhard Staber
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Journal Articles

Reassessing the chronic lymphocytic leukemia International Prognostic Index in the era of targeted therapies

Clinical Trials & Observations
Petra Langerbeins, Adam Giza, Sandra Robrecht, Paula Cramer, Julia von Tresckow, Othman Al-Sawaf, Anna Maria Fink, Moritz Fürstenau, Nadine Kutsch, Florian Simon, Valentin Goede, Manuela Hoechstetter, Carsten Utoft Niemann, Caspar da Cunha-Bang, Arnon Kater, Julie Dubois, Michael Gregor, Philipp Bernhard Staber, Eugen Tausch, Christof Schneider, Stephan Stilgenbauer, Barbara Eichhorst, Kirsten Fischer, Michael Hallek
Journal: Blood
Blood (2024) 143 (25): 2588–2598.
https://doi.org/10.1182/blood.2023022564
Published: 2024
Includes: Supplemental data
Journal Articles

Functional Precision Medicine Vs Genomics Vs Clinical Experience: Feasibility Results from the Multicentric, Prospective, Randomized Controlled Exalt-2 Trial

Lukas Kazianka, Tea Pemovska, Johannes Rohrbeck, Christoph Kornauth, Alexander Pichler, Christiane Agreiter, Simone Lubowitzki, Katharina Prochazka, Peter Neumeister, Clemens Schmitt, Richard Greil, Wolfgang Willenbacher, Dominik Wolf, Ulrich Jaeger, Ingrid Simonitsch-Klupp, Philipp Bernhard Staber
Journal: Blood
Blood (2023) 142 (Supplement 1): 5006.
https://doi.org/10.1182/blood-2023-189856
Published: 2023
Journal Articles

Distinct Subtypes of Chemotherapy-Resistant Systemic ALK-Positive Anaplastic Large Cell Lymphoma Demonstrate Long-Term Complete Remissions to Imatinib

Alexander Pichler, Christoph Kornauth, Ines Garces De Los Fayos Alonso, Lukas Kazianka, Arne Zibat, Luca Mologni, Halima Alachram, Tea Pemovska, Gerwin Heller, Richard Greil, Lukas Kenner, Ulrich Jaeger, Philipp Bernhard Staber
Journal: Blood
Blood (2023) 142 (Supplement 1): 1691.
https://doi.org/10.1182/blood-2023-188835
Published: 2023
Journal Articles

Tislelizumab Plus Zanubrutinib in Patients with Richter Transformation: Primary Endpoint Analysis of the Prospective, Multi-Center, Phase-II RT1 Trial of the German CLL Study Group

Othman Al-Sawaf, Rudy Ligtvoet, Sandra Robrecht, Janina Stumpf, Anna Maria Fink, Eugen Tausch, Christof Schneider, Sebastian Böttcher, Martin Mikusko, Matthias Ritgen, Johannes Schetelig, Julia Von Tresckow, Ursula Vehling-Kaiser, Clemens-Martin Wendtner, Kirsten Fischer, Karl Anton Kreuzer, Stephan Stilgenbauer, Philipp Bernhard Staber, Carsten Utoft Niemann, Michael Hallek, Barbara F. Eichhorst
Journal: Blood
Blood (2023) 142 (Supplement 1): 204.
https://doi.org/10.1182/blood-2023-188705
Published: 2023
Journal Articles

First-Line Venetoclax Combinations in Fit Patients with CLL: 4-Year Follow-up and NGS-Based MRD Analysis from the Phase 3 GAIA/CLL13 Trial

Moritz Fürstenau, Matthias Ritgen, Sandra Robrecht, Julia Von Tresckow, Can Zhang, Anke Schilhabel, Michael Gregor, Patrick Thornton, Philipp Bernhard Staber, Tamar Tadmor, Vesa Lindström, Gunnar Juliusson, Ann Janssens, Mark-David Levin, Caspar Da Cunha-Bang, Christof Schneider, Neta Goldschmidt, Elisabeth Vandenberghe, Davide Rossi, Rudolf A. Benz, Daniel Heintel, Christian Bjørn Poulsen, Ilse Christiansen, Henrik Frederiksen, Lisbeth Enggaard, Eduardus Posthuma, Djamila Issa, Hein Visser, Mar Bellido, Nadine Kutsch, Jan Dürig, Alexander Stehle, Matthias C. Voehringer, Sebastian Böttcher, Clemens Schulte, Florian Simon, Anna-Maria Fink, Kirsten Fischer, Emily Holmes, Karl-Anton Kreuzer, Monika Brüggemann, Eugen Tausch, Stephan Stilgenbauer, Michael Hallek, Arnon P. Kater, Carsten Utoft Niemann, Barbara F. Eichhorst
Journal: Blood
Blood (2023) 142 (Supplement 1): 635.
https://doi.org/10.1182/blood-2023-173709
Published: 2023
Journal Articles

Endpoint Surrogacy in Chronic Lymphocytic Leukemia: A Pooled Analysis of the German CLL Study Group

Florian Simon, Rudy Ligtvoet, Sandra Robrecht, Paula Cramer, Nadine Kutsch, Moritz Furstenau, Valentin Goede, Julia Von Tresckow, Petra Langerbeins, Anna-Maria Fink, Henriette Huber, Eugen Tausch, Christof Schneider, Clemens-Martin Wendtner, Matthias Ritgen, Martin Dreyling, Lothar Müller, Lutz Jacobasch, Werner Heinz, Ursula Vehling-Kaiser, Liliya Sivcheva, Sebastian Böttcher, Peter Dreger, Thomas Illmer, Michael Gregor, Philipp Bernhard Staber, Stephan Stilgenbauer, Carsten Utoft Niemann, Arnon P. Kater, Kirsten Fischer, Barbara F. Eichhorst, Michael Hallek, Othman Al-Sawaf
Journal: Blood
Blood (2023) 142 (Supplement 1): 1901.
https://doi.org/10.1182/blood-2023-178597
Published: 2023
Journal Articles

The Impact of Fitness and Dose Intensity on Safety and Efficacy Outcomes after Venetoclax-Obinutuzumab in Previously Untreated Chronic Lymphocytic Leukemia

Othman Al-Sawaf, Moritz Fürstenau, Adam Giza, Sandra Robrecht, Julia Von Tresckow, Anna Maria Fink, Florian Simon, Eugen Tausch, Christof Schneider, Liliya Sivcheva, Anthony Schwarer, Javier Loscertales, Robert Weinkove, Dirk Strumberg, Allanah R. Kilfoyle, Gunnar Juliusson, Caspar Da Cunha-Bang, Thomas Illmer, Michael Gregor, Patrick Thornton, Ann Janssens, Tamar Tadmor, Vesa Lindström, Philipp Bernhard Staber, Mark-David Levin, Clemens-Martin Wendtner, Karl-Anton Kreuzer, Matthias Ritgen, Stephan Stilgenbauer, Arnon P. Kater, Carsten Utoft Niemann, Kirsten Fischer, Barbara F. Eichhorst, Michael Hallek
Journal: Blood
Blood (2023) 142 (Supplement 1): 4639.
https://doi.org/10.1182/blood-2023-188827
Published: 2023
Journal Articles

Imatinib +/- Brentuximab Vedotin Induces Sustained Complete Remission in Chemotherapy-Resistant Anaplastic Large Cell Lymphoma Expressing PDGFR

Philipp Bernhard Staber, MD PhD, Christoph Kornauth, Ines Garces de los Fayos Alonso, Wilhelm Woessmann, MD, Wolfram Klapper, Sabine Lagger, Ana-Iris Schiefer, Cathrin Skrabs, Olaf Merkel, PhD, Marius E Mayerhoefer, Richard Greil, MD, Ingrid Simonitsch-Klupp, MD, Lukas Kenner, MD, Ulrich Jaeger, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4037.
https://doi.org/10.1182/blood-2019-129955
Published: 2019
Journal Articles

A Phase Ib, Open-Label, Randomized Study to Assess Safety and Preliminary Efficacy of Tafasitamab (MOR208) or Tafasitamab + Lenalidomide in Addition to R-CHOP in Patients with Newly Diagnosed Diffuse Large B-Cell Lymphoma: The First-Mind Trial

John M Burke, MD, Marc André, Bruce D. Cheson, MD, Johannes Duell, MD, Grzegorz Nowakowski, MD, Andreas Rosenwald, MD, Gilles A. Salles, MD PhD, Jeff P. Sharman, MD, Philipp Bernhard Staber, MD PhD, Marek Trněný, MD, Jason R. Westin, MD, Wolfram Brugger, Günter Fingerle-Rowson, MD PhD, Magdalena Klanova, Guido Würth, PhD, Lorenz Truemper, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2877.
https://doi.org/10.1182/blood-2019-128021
Published: 2019
Journal Articles

Combination of Venetoclax and Ibrutinib Increases bcl2-Dependent Apoptotic Priming, Reduces ITK-Phosphorylation and Is Clinically Promising in Relapsed/Refractory T-Prolymphocytic Leukemia

Christoph Kornauth, Charles Herbaux, MD MSc, Bernd Boidol, PhD, Chantal Guillemette, Patrick Caron, Stéphanie Poulain, MD PhD, Olivier Tournilhac, Marius E Mayerhoefer, Ulrich Jaeger, MD, Stefan Kubicek, Matthew S. Davids, MD, Philipp Bernhard Staber, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3965.
https://doi.org/10.1182/blood-2019-124392
Published: 2019
Journal Articles

In Human Visualization of Ibrutinib-Induced CLL Compartment Shift

Marius E Mayerhoefer, Alexander Haug, Ulrich Jaeger, MD, Lukas Kazianka, MD, Verena Pichler, Sarah Pfaff, Hans-Jürgen Wester, PhD, Marcus Hacker, Philipp Bernhard Staber, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1750.
https://doi.org/10.1182/blood-2019-131469
Published: 2019
Journal Articles

Primary Analysis of Anti-CD19 Tafasitamab (MOR208) Treatment in Combination with Idelalisib or Venetoclax in R/R CLL Patients Who Failed Prior BTK Inhibitor Therapy (COSMOS Trial)

Philipp Bernhard Staber, MD PhD, Wojciech Jurczak, Wolfram Brugger, Asher A. Chanan-Khan, MD, Richard Greil, MD, Andrzej Hellmann, MD PhD, Maren Dirnberger-Hertweck, PhD, Peter Kelemen, Jan Moritz Middeke, MD, Marco Montillo, MD, Marina Motta, MD, Talha Munir, MD, Peter Neumeister, MD, Dietger Niederweiser, MD, Sameer A. Parikh, MD, Johannes Schetelig, MDMSc, Stephan Stilgenbauer, Vladan Vucinic, MD, Johannes Weirather, PhD, Jennifer Woyach, MD, Clemens-Martin Wendtner
Journal: Blood
Blood (2019) 134 (Supplement_1): 1754.
https://doi.org/10.1182/blood-2019-128388
Published: 2019
Journal Articles

Characterizing the Anti-Apoptotic Dependencies of T-Cell Prolymphocytic Leukemia Identifies HDAC and JAK/STAT Pathway Inhibitors As Promising Combination Partners to Augment Bcl-2 Targeted Killing By Venetoclax

Charles Herbaux, MD MSc, Christoph Kornauth, Stéphanie Poulain, MD PhD, Olivier Tournilhac, Mary C Collins, BA, Rebecca Valentin, MD, Stephen Jun Fei Chong, PhD, Jehan Dupuis, MD, Adrien Daniel, Micha Srour, MD, Cecile Tomowiak, MD, Kamel Laribi, MD, Damien Roos-Weil, Cedric Rossi, MD PhD, Nicolas Vanlangendonck, MSc, Cecile Leyronnas, Fatiha Merabet, MD, Jean Valère Malfuson, MD, Mourad Tiab, Samuel Ng, MD PhD, Franck Morschhauser, MD, Philipp Bernhard Staber, MD PhD, Matthew S. Davids, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 807.
https://doi.org/10.1182/blood-2019-126773
Published: 2019
Journal Articles

Two-Cohort Phase II Study in R/R CLL (COSMOS): First Preliminary Safety and Efficacy Results of Anti-CD19 MOR208 Treatment in Combination with Venetoclax in Patients Who Discontinued Prior BTK Inhibitor Therapy

Philipp Bernhard Staber, MD PhD, Asher A. Chanan-Khan, MD, Talha Munir, Dietger Niederweiser, Johannes Schetelig, MD MSc, Jan Moritz Middeke, MD, Maren Dirnberger-Hertweck, PhD, Peter Kelemen, Johannes Weirather, PhD, Sameer A. Parikh, MD, Stephan Stilgenbauer, MD PhD, Clemens-Martin Wendtner, Jennifer A. Woyach, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4433.
https://doi.org/10.1182/blood-2018-99-114489
Published: 2018
Journal Articles

Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy

Clinical Trials & Observations
Edit Porpaczy, Sabrina Tripolt, Andrea Hoelbl-Kovacic, Bettina Gisslinger, Zsuzsanna Bago-Horvath, Emilio Casanova-Hevia, Emmanuelle Clappier, Thomas Decker, Sabine Fajmann, Daniela A. Fux, Georg Greiner, Sinan Gueltekin, Gerwin Heller, Harald Herkner, Gregor Hoermann, Jean-Jacques Kiladjian, Thomas Kolbe, Christoph Kornauth, Maria-Theresa Krauth, Robert Kralovics, Leonhard Muellauer, Mathias Mueller, Michaela Prchal-Murphy, Eva Maria Putz, Emmanuel Raffoux, Ana-Iris Schiefer, Klaus Schmetterer, Christine Schneckenleithner, Ingrid Simonitsch-Klupp, Cathrin Skrabs, Wolfgang R. Sperr, Philipp Bernhard Staber, Birgit Strobl, Peter Valent, Ulrich Jaeger, Heinz Gisslinger, Veronika Sexl
Journal: Blood
Blood (2018) 132 (7): 694–706.
https://doi.org/10.1182/blood-2017-10-810739
Published: 2018
Includes: Supplemental data
Journal Articles

First in Human Response of BCL-2 Inhibitor Venetoclax in T-Cell Prolymphocytic Leukemia

Bernd Boidol, Christoph Kornauth, MD, Emiel van der Kouwe, Nicole Prutsch, Lukas Kazianka, MD, Gregor Hoermann, MD, Georg Hopfinger, MD, Alexander Hauswirth, MD, Marie-Bernadette Aretin, Wolfgang R. Sperr, MD, Peter Valent, MD, Ingrid Simonitsch-Klupp, MD, Richard Morrigl, PhD, Olaf Merkel, PhD, Lukas Kenner, MD, Ulrich Jaeger, MD, Stefan Kubicek, PhD, Philipp Bernhard Staber, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 575.
https://doi.org/10.1182/blood.V130.Suppl_1.575.575
Published: 2017
Journal Articles

Integration of Functional Ex Vivo Drug Testing and Molecular Profiling Reveals Novel Vulnerabilities in CMML

Tea Pemovska, PhD, Gregory Ian Vladimer, PhD, Vitaly Sedlyarov, PhD, Emir Hadzijusufovic, DVM, Karoline Veronika Gleixner, MD, Alexandra Keller, MSc, Berend Snijder, PhD, Nikolaus Krall, PhD, Oscar Lopez de la Fuente, BSc, Mathias A Schneeweiss, MD, Wolfgang R. Sperr, MD, Paul Knöbl, MD PhD, Klaus Geissler, MD, Philipp Bernhard Staber, MD PhD, Ulrich Jaeger, MD, Peter Valent, MD, Giulio Superti Furga, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4227.
https://doi.org/10.1182/blood.V130.Suppl_1.4227.4227
Published: 2017
Journal Articles

Next-Generation Functional Drug Screening for Patients with Aggressive Hematologic Malignancies

Philipp Bernhard Staber, MD PhD, Berend Snijder, PhD, Gregory Ian Vladimer, PhD, Nikolaus Krall, PhD, Katsuhiro Miura, MD, Ann-Sofie Schmolke, Christoph Kornauth, MD, Oscar Lopez de la Fuente, BSc, Hye-Soo Choi, Emiel van der Kouwe, Lukas Kazianka, MD, Johannes Bigenzahn1, MD PhD, Gregor Hoermann, MD, Nicole Prutsch, Olaf Merkel, PhD, Anna Ringler, Georg Jeryczynski, MD, Marius Mayerhoefer, MD, Ingrid Simonitsch-Klupp, MD, Franz X Felberbauer, MD, Leonhard Muellauer, MD PhD, Gerald W Prager, MD, Belgin Korkmaz, MD, Lukas Kenner, MD, Wolfgang R. Sperr, MD, Robert Kralovics, PhD, Heinz Gisslinger, Peter Valent, MD, Stefan Kubicek, PhD, Ulrich Jaeger, MD, Giulio Superti-Furga, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 855.
https://doi.org/10.1182/blood.V130.Suppl_1.855.855
Published: 2017
Journal Articles

JAK2-Inhibitor Therapy Associated Lymphomas in Myelofibrosis: Distinct Clinico-Pathological Features Recapitulated in a Mouse Model

Sabrina Tripolt, PhD, Edit Anna Porpaczy, MD, Andrea Hoelbl-Kovacic, PhD, Bettina Gisslinger, Zsuzanna Bago-Horvath, PhD, Emilio Casanova, PhD, Thomas Decker, PhD, Daniela Fux, PhD, Gerwin Heller, MD, Harald Herkner, MD, Thomas Kolbe, PhD, Christoph Kornauth, MD, Mathias Mueller, PhD, Michaela Prchal-Murphy, PhD, Ana Iris Schiefer, MD, Christine Schneckenleithner, PhD, Cathrin Skrabs, MD, Wolfgang R. Sperr, MD, Philipp Bernhard Staber, MD PhD, Birgit Strobl, PhD, Peter Valent, MD, Ingrid Simonitsch-Klupp, MD, Gregor Hoermann, MD, Jean-Jacques Kiladjian, MD PhD, Robert Kralovics, PhD, Maria-Theresa Krauth, MD, Ulrich Jaeger, MD, Veronika Sexl, MD PhD, Heinz Gisslinger
Journal: Blood
Blood (2017) 130 (Supplement 1): 1643.
https://doi.org/10.1182/blood.V130.Suppl_1.1643.1643
Published: 2017
Journal Articles

Integrated ATAC-Seq and Chemosensitivity Profiling Identifies Rational Drug Combinations in Ibrutinib-Treated CLL Patients

Gregory Ian Vladimer, PhD, Christian Schmidl, PhD, Andre Renderio, MS, Susanne Schnabl, MS, Tea Pemovska, PhD, Berend Snijder, PhD, Thomas Krausgruber, PhD, Nikolaus Krall, PhD, Mohammad Araghi, Rainer Hubmann, Anna Ringler, Dita Demirtas, Oscar Lopez de la Fuente, BSc, Martin Hilgrath, Cathrin Skrabs, MD, Edit Anna Porpaczy, MD, Michaela Gruber, MD PhD, Gregor Hoermann, MD, Stefan Kubicek, PhD, Philipp Bernhard Staber, MD PhD, Medhat M. Shehata, MD, Giulio Superti-Furga, PhD, Christoph Bock, PhD, Ulrich Jaeger, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 800.
https://doi.org/10.1182/blood.V130.Suppl_1.800.800
Published: 2017