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Bakir Valentic
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Journal Articles

Single-day non-activated IL-18-armed CAR T cells with enhanced persistence and durable efficacy

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Joseph Durgin, Shin Seo, Shadab Kazmi, Bakir Valentic, Chloe Leff, Xioling Jin, Feng Shen, Nandana Mukherjee, Ashwin Sannecy, Gabriela Plesa, Khatuna Gabunia, John Scholler, Saar Gill, Roddy O'Connor, Carl June, Saba Ghassemi
Journal: Blood
Blood (2025) 146 (Supplement 1): 4187.
https://doi.org/10.1182/blood-2025-4187
Published: 2025
Journal Articles

Glucose transporter 5 enhances CAR-T cell metabolic function and serial killing

Free
Bakir Valentic, Andre Kelly, Feng Shen, John Scholler, Max Shestov, Nathaniel Snyder, Saba Ghassemi, Nicholas Jones, Saar Gill, Roddy O'Connor
Journal: Blood
Blood (2025) 146 (Supplement 1): 2351.
https://doi.org/10.1182/blood-2025-2351
Published: 2025
Journal Articles

Metabolic conditioning for enhanced CAR T cell function

Free
Yufan Zhou, Andre Kelly, Tyler Quarton, Bakir Valentic, Andrew Frisch, Zhiyang Gan, Alexander Shestov, Noah Ford, Jai Patel, Shimin Liu, Khatuna Gabunia, Joseph Durgin, Xiangyi Fang, Max Wadley, Sophie Trefely, Lindsay Pino, Francisca deLuna Vitorino, Dawei Liu, Eliana Von Krusenstiem, Natalia Romero, John Lawson, Benjamin Garcia, Nathaniel Snyder, Saba Ghassemi, John Scholler, Carl June, Roddy O'Connor
Journal: Blood
Blood (2025) 146 (Supplement 1): 4127.
https://doi.org/10.1182/blood-2025-4127
Published: 2025
Journal Articles

In Vivo Persistence and Function of CAR19 T-Cell Products for Pediatric B-Cell Acute Lymphoblastic Leukemia Are Impacted By Media, Cytokine Supplementation and Metabolite Bioavailability during Ex Vivo Manufacturing

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Caitlin R. Hopkins, Amanda M. DiNofia, Shannon L. Maude, Gregory M. Chen, Kwame Attah M. Boateng-Antwi, Jessica Perazzelli, Andres F. Mendez Corea, Alexander Shestov, Mercy Gohil, Yimei Li, Wei-Ting Hwang, Bakir Valentić, Shannon Christensen, Julie Jadlowsky, Regina M. Myers, Caroline Diorio, Megan M. Davis, Theresa Colligon, Gabriela Plesa, Don L. Siegel, Bruce Levine, Carl H. June, Roddy S. O'Connor, Stephan A. Grupp, Joseph A. Fraietta
Journal: Blood
Blood (2024) 144 (Supplement 1): 3473.
https://doi.org/10.1182/blood-2024-210324
Published: 2024