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Andrei Thomas-Tikhonenko
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Journal Articles

Lymphoma immunotherapy: the garden of forking paths

Zhiwei Ang, Andrei Thomas-Tikhonenko
Journal: Blood
Blood (2024) 143 (8): 655–657.
https://doi.org/10.1182/blood.2023023202
Published: 2024
Journal Articles

Alternative splicing of its 5′-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies

Zhiwei Ang, Luca Paruzzo, Katharina E. Hayer, Carolin Schmidt, Manuel Torres Diz, Feng Xu, Urvi Zankharia, Yunlin Zhang, Samantha Soldan, Sisi Zheng, Catherine D. Falkenstein, Joseph P. Loftus, Scarlett Y. Yang, Mukta Asnani, Patricia King Sainos, Vinodh Pillai, Emeline Chong, Marilyn M. Li, Sarah K. Tasian, Yoseph Barash, Paul M. Lieberman, Marco Ruella, Stephen J. Schuster, Andrei Thomas-Tikhonenko
Journal: Blood
Blood (2023) 142 (20): 1724–1739.
https://doi.org/10.1182/blood.2023020400
Published: 2023
Includes: Supplemental data
Journal Articles

HMGA1-ETV5 Axis Is Essential for Relapsed B-Cell Leukemia and Provides Novel Therapeutic Targets

Jung-Hyun Kim, Liping Li, Zixin Zhang, Katharina Hayer, Li Luo, Leslie Cope, Lingling Xian, Andrei Thomas-Tikhonenko, Linda Resar
Journal: Blood
Blood (2022) 140 (Supplement 1): 3478–3479.
https://doi.org/10.1182/blood-2022-167037
Published: 2022
Journal Articles

Non-Canonical Exon Usage in Pediatric Leukemia: Implications for Chemoresistance

Manuel Torres-Diz, Andrei Thomas-Tikhonenko, Clara Reglero, Adolfo Ferrando, Catherine D Falkenstein, Sarah K Tasian, Priyanka Sehgal, Zhiwei Ang, Yoseph Barash, Caleb Radens
Journal: Blood
Blood (2022) 140 (Supplement 1): 3264–3265.
https://doi.org/10.1182/blood-2022-167006
Published: 2022
Journal Articles

Identification of a Conserved Intracellular Loop (CIL) Structure That Scaffolds PIP3 to Amplify Oncogenic Signaling during Malignant B-Cell Transformation

Jaewoong Lee, Mark E. Robinson, Ning Ma, Teresa Sadras, Kadriye Nehir Cosgun, Lai N. Chan, Kohei Kume, Andrei Thomas-Tikhonenko, David M. Weinstock, Michael S. Diamond, Nagarajan Vaidehi, Markus Müschen
Journal: Blood
Blood (2021) 138 (Supplement 1): 868.
https://doi.org/10.1182/blood-2021-149646
Published: 2021
Journal Articles

High Mobility Group A1 (HMGA1) Epigenetic Regulators Induce ETV5 Networks in Relapsed B-Cell Leukemia and Provide Novel Therapeutic Targets

Jung-Hyun Kim, Liping Li, Zixin Zhang, Katharina Hayer, Lingling Xian, Li Luo, Leslie Cope, Andrei Thomas-Tikhonenko, Linda Resar
Journal: Blood
Blood (2021) 138 (Supplement 1): 707.
https://doi.org/10.1182/blood-2021-152950
Published: 2021
Journal Articles

High Mobility Group A1 Chromatin Regulators Function As Critical Drivers of Leukemogenesis in Preclinical Models of Relapsed, Pediatric B-Cell ALL

Liping Li, MD PhD, Katharina Hayer, Lingling Xian, MD PhD, Li Luo, PhD, Leslie Cope, Andrei Thomas-Tikhonenko, PhD, Linda Resar, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3946.
https://doi.org/10.1182/blood-2019-130261
Published: 2019
Journal Articles

Ifitm3 Is Essential for PI(3,4,5)P3-Dependent B-Cell Activation and Leukemogenesis

Jaewoong Lee, PhD, Gang Xiao, PhD, Kadriye Nehir Nehir Cosgun, PhD, Huimin Geng, PhD, Ning Ma, PhD, Lai N Chan, PhD, Kohei Kume, PhD, Matthew Nix, PhD, Zhengshan Chen, MD PhD, Chun-Wei David Chen, PhD, Jianjun Chen, PhD, Vishal Khairnar, PhD, Arun P. Wiita, MD PhD, Andrei Thomas-Tikhonenko, PhD, Michael Farzan, MD PhD, Michael S. Diamond, PhD, Jae U Jung, PhD, Nagarajan Vaidehi, PhD, Markus Müschen, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2782.
https://doi.org/10.1182/blood-2019-127615
Published: 2019
Journal Articles

Efficacy Proof of Concept for Allogeneic CD123 Targeting CAR T-Cells Against Primary Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN): Efficient Control of Tumor Progression in PDX Model and Potential Loss of CD123 Expression in Relapsed Disease

Tianyu Cai, PhD, Kathryn L Black, PhD, Ammar S. Naqvi, PhD, Deanne Taylor, PhD, Ming Zhao, MD, Qi Yuan, Mayumi Sugita, MD, Roman Galetto, PhD, Agnès Gouble, PhD, Julianne N. P. Smith, PhD, Antonio Cavazos, Lina Han, PhD, Qi Zhang, PhD, Vinitha Mary Kuruvilla, MSc, Helen Ma, MS, Sergej Konoplev, Guilin Tang, MD, Jun Gu, MD PhD, Xiaoping Su, PhD, Sattva S Neelapu, MD, Andrew A. Lane, MD PhD, Hagop M. Kantarjian, MD, Monica L. Guzman, PhD, Naveen Pemmaraju, MD, Andrei Thomas-Tikhonenko, PhD, Marina Y Konopleva, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2659.
https://doi.org/10.1182/blood-2019-126869
Published: 2019
Journal Articles

Pipeline for Discovering Neoepitopes Generated By Alternative Splicing in B-ALL

Sisi Zheng, MD, Ammar S. Naqvi, PhD, Elisabeth Bolton-Gillespie, Mukta Asnani, Katharina Hayer, Yoseph Barash, PhD, Andrei Thomas-Tikhonenko, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1342.
https://doi.org/10.1182/blood-2019-131277
Published: 2019
Journal Articles

The Impact of Immunotherapy on Tumor Evolution

Andrei Thomas-Tikhonenko, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): SCI-18.
https://doi.org/10.1182/blood-2018-99-109434
Published: 2018
Journal Articles

Semi-Quantitative Analysis of CD19 and CD22 Expression in B-Lymphoblastic Leukemia and Implications for Targerted Immunotherapy

Jaclyn Rosenthal, BSN, Ammar S. Naqvi, PhD, Gerald Wertheim, MD PhD, Michele Paessler, D.O., Susan R. Rheingold, MD, Andrei Thomas-Tikhonenko, PhD, Vinodh Pillai, MD, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1331.
https://doi.org/10.1182/blood.V130.Suppl_1.1331.1331
Published: 2017
Journal Articles

Regulation of CD19 Exon 2 Inclusion in B-Lymphoid Cells By Splicing Factors and Epigenetic Marks

Kathryn Black, PhD, Elena Sotillo, PhD, Nicole Martinez, Matthew Gazzara, Alejandro Barrera, Yoseph Barash, PhD, Kristen Lynch, PhD, Andrei Thomas-Tikhonenko, PhD
Journal: Blood
Blood (2015) 126 (23): 2425.
https://doi.org/10.1182/blood.V126.23.2425.2425
Published: 2015
Journal Articles

The Importance of CD19 Exon 2 for Surface Localization: Closing the Ig-like Loop

Asen Bagashev, PhD, Elena Sotillo, PhD, Glendon Wu, Andrei Thomas-Tikhonenko, PhD
Journal: Blood
Blood (2015) 126 (23): 3433.
https://doi.org/10.1182/blood.V126.23.3433.3433
Published: 2015
Journal Articles

The Myc-miR-17-92 axis amplifies B-cell receptor signaling via inhibition of ITIM proteins: a novel lymphomagenic feed-forward loop

James N. Psathas, Patrick J. Doonan, Pichai Raman, Bruce D. Freedman, Andy J. Minn, Andrei Thomas-Tikhonenko
Journal: Blood
Blood (2013) 122 (26): 4220–4229.
https://doi.org/10.1182/blood-2012-12-473090
Published: 2013
Includes: Supplemental data
Journal Articles

Pax5 Activates Oncogenic Transcription Factors of the Ets Family by Repressing the mir-15a/16-1 microRNA Cluster.

Elaine Y. Chung, Ph.D., Diana Cozma, M.D., Duonan Yu, Ph.D., Michael Dews, Ph.D., Erik A. Wentzel, Tsung-Cheng Chang, Joshua T. Mendell, M.D., Ph.D., Andrei Thomas-Tikhonenko, PhD
Journal: Blood
Blood (2007) 110 (11): 346.
https://doi.org/10.1182/blood.V110.11.346.346
Published: 2007
Journal Articles

p53 status dictates responses of B lymphomas to monotherapy with proteasome inhibitors

Duonan Yu, Martin Carroll, Andrei Thomas-Tikhonenko
Journal: Blood
Blood (2007) 109 (11): 4936–4943.
https://doi.org/10.1182/blood-2006-10-050294
Published: 2007
Journal Articles

Chloroquine Inhibits Autophagy, Enhances p53-Dependent Apoptosis, and Delays Tumor Recurrence in a Mouse Model of B Cell Lymphoma.

Ravi K. Amaravadi, MD, Duonan Yu, PhD, Andrei Thomas-Tikhonenko, PhD, Craig B. Thompson, MD
Journal: Blood
Blood (2005) 106 (11): 2421.
https://doi.org/10.1182/blood.V106.11.2421.2421
Published: 2005
Journal Articles

Oscillation between B-lymphoid and myeloid lineages in Myc-induced hematopoietic tumors following spontaneous silencing/reactivation of the EBF/Pax5 pathway

Duonan Yu, David Allman, Michael H. Goldschmidt, Michael L. Atchison, John G. Monroe, Andrei Thomas-Tikhonenko
Journal: Blood
Blood (2003) 101 (5): 1950–1955.
https://doi.org/10.1182/blood-2002-06-1797
Published: 2003