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Journal Articles

Preclinical Efficacy and Mechanism for a Novel BTK-Protacs Against Mantle Cell Lymphoma

Yue Fei, Xiaohui Wang, Shangzhe Yu, Yixin Yao, Guisen Zhao, Xianhuo Wang, Huilai Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 2267.
https://doi.org/10.1182/blood-2023-185275
Published: 2023
Journal Articles

YAP1-Dependent Promotion of Downstream Transcription through BRD4 Mediates Selinexor Resistance in Diffuse Large B-Cell Lymphoma

Xiaoxuan Wang, Yidan Zhang, Xianyou Xia, Yixin Yao, Xudong Wu, Xianhuo Wang, Huilai Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 2823.
https://doi.org/10.1182/blood-2023-185242
Published: 2023
Journal Articles

The Reversible BTK Inhibitor Nemtabrutinib Demonstrates Favorable Antitumor Efficacy and Enhances the Function of CAR T Cells in Mantle Cell Lymphoma

Margaret Elizabeth Simmons, Joseph McIntosh, Tianci Zhang, Yijing Li, Fangfang Yan, Yixin Yao, Lei Nie, Heng-Huan Lee, Wei Wang, Vivian Changying Jiang, Michael Wang, Yang Liu
Journal: Blood
Blood (2023) 142 (Supplement 1): 5789.
https://doi.org/10.1182/blood-2023-187405
Published: 2023
Journal Articles

Integrative Genomic and Transcriptomic Analysis Reveals Genetic Alterations Associated with the Early Progression of Follicular Lymphoma

Fenghua Gao, Hengqi Liu, Xianhuo Wang, Yixin Yao, Huilai Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 3022.
https://doi.org/10.1182/blood-2023-174182
Published: 2023
Journal Articles

Exploring BiTE-Integrated CAR T-Cell Therapy to Overcome Tumor Antigen Escape and Reinforce CAR-T Therapy in Mantle Cell Lymphoma

Grace Glass Crutchfield, Yang Liu, Fangfang Yan, Xiaolin Li, Heng-Huan Lee, Michael Wang, Yixin Yao
Journal: Blood
Blood (2023) 142 (Supplement 1): 6820.
https://doi.org/10.1182/blood-2023-190167
Published: 2023
Journal Articles

A Prospective Phase II Study of Radiotherapy Followed By Tiselizumab Combined with R-CHOP in the Untreated Follicular Lymphoma Patients with Bulky Disease in China

Wei Li, Ximei Zhang, Fenghua Gao, Yixin Yao, Xianhuo Wang, Huilai Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 1687.
https://doi.org/10.1182/blood-2023-185752
Published: 2023
Journal Articles

CD58 Genetic Alterations and Its Contribution to Upregulation of PD-L1 and IDO Via LYN/CD22/SHP1 Axis in DLBCL

Xiyue Xu, Qingpei Guan, Lanfang Li, Lihua Qiu, Zhengzi Qian, Shiyong Zhou, Yixin Yao, Xianhuo Wang, Huilai Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 524.
https://doi.org/10.1182/blood-2023-188468
Published: 2023
Journal Articles

Azacitidine for Injection Combined with Chidamide in Relapsed/Refractory Peripheral T-Cell Lymphoma: A Phase I Study

Jingwei Yu, Yaxiao Lu, Yixin Yao, Xianming Liu, Lanfang Li, Zhengzi Qian, Lihua Qiu, Shiyong Zhou, Xianhuo Wang, Huilai Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 3076.
https://doi.org/10.1182/blood-2023-188801
Published: 2023
Journal Articles

Modulating Immunometabolism to Reinvigorate T-Cell Effector Function and Antitumor Immunity in the Mantle Cell Lymphoma Microenvironment

Yixin Yao, Yang Liu, Yuxuan Che, Yijing Li, Heng-Huan Lee, Michael L. Wang, Joseph McIntosh
Journal: Blood
Blood (2022) 140 (Supplement 1): 6446–6447.
https://doi.org/10.1182/blood-2022-169543
Published: 2022
Journal Articles

HSP27 Promotes Mantle Cell Lymphoma Growth and Mediates Resistance to Venetoclax

Yuxuan Che, Wei Wang, Yang Liu, Heng-Huan Lee, Yijing Li, Zhihong Chen, Joseph McIntosh, Changying Jiang, Yixin Yao, Michael Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 6405–6406.
https://doi.org/10.1182/blood-2022-167611
Published: 2022
Journal Articles

Targeting the HSP90-MYC-CDK9 Axis to Overcome Dual Resistance to BTK Inhibition and CAR-T Therapy in Mantle Cell Lymphoma

Vivian Changying Jiang, Fangfang Yan, Alexa A Jordan, Yuxuan Che, Yang Liu, Qingsong Cai, Yijing Li, Joseph McIntosh, Zhihong Chen, Jovanny Vargas, Yixin Yao, Heng-Huan Lee, Jingling Jin, Wei Wang, Lei Nie, Zhongming Zhao, Lukas M Simon, Michael L. Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 3512–3513.
https://doi.org/10.1182/blood-2022-163696
Published: 2022
Journal Articles

Establishment of a Patient-Derived Organoid Culture Platform for Mantle Cell Lymphoma Drug Sensitivity and CAR T Cell Anti-Tumor Activity Assay

Lei Nie, Yang Liu, Changying Jiang, Yuxuan Che, Jingling Jin, Qingsong Cai, Wei Wang, Yijing Li, Alexa A Jordan, Joseph McIntosh, Jovanny Vargas, Yixin Yao, Heng-Huan Lee, Michael L. Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 9219–9220.
https://doi.org/10.1182/blood-2022-169622
Published: 2022
Journal Articles

Establishment of Patient-Derived Organoid Culture Platform of Mantle Cell Lymphoma

Lei Nie, Yang Liu, Yuxuan Che, Yijing Li, Wei Wang, Jingling Jin, Qingsong Cai, Jovanny Vargas, Joseph McIntosh, Alexa A Jordan, Vivian Changying Jiang, Yixin Yao, Michael Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 3508.
https://doi.org/10.1182/blood-2021-152994
Published: 2021
Journal Articles

Immune-Depleted Tumor Microenvironment Signature Is Associated with BTK Inhibitor Resistance in Mantle Cell Lymphoma

Preetesh Jain, Krystle Nomie, Vitaly Segodin, Evgeniy Egorov, Yixin Yao, Lucy Navsaria, Holly Hill, Nikita Kotlov, Rashmi Kanagal-Shamanna, Chi Young Ok, Francisco Vega, Shaoying Li, Yuxuan Che, Yijing Li, Viktor Svekolkin, Alexander Bagaev, Felix Frenkel, Ravshan Attaulakhanov, Nathan H. Fowler, Christopher R. Flowers, Michael Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 1321.
https://doi.org/10.1182/blood-2021-151416
Published: 2021
Journal Articles

Bispecific CD19-CD20 and CD19-CD22 CAR-T Cells with Glycogen Synthase Kinase (GSK)-3β Inhibitor TWS119 Treatment Have Superior Therapeutic Effects on Mantle Cell Lymphoma

Jingling Jin, Yijing Li, Yang Liu, Alexa A Jordan, Joseph McIntosh, Jovanny Vargas, Yuxuan Che, Yixin Yao, Michael Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 1698.
https://doi.org/10.1182/blood-2021-150000
Published: 2021
Journal Articles

Abemaciclib in Combination with Copanlisib to Overcome Therapeutic Resistance in Mantle Cell Lymphoma

Yuxuan Che, Yang Liu, Yijing Li, Joseph McIntosh, Alexa A Jordan, Zhihong Chen, Fangfang Yan, Wei Wang, Jingling Jin, Changying Jiang, Yixin Yao, Michael Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 2253.
https://doi.org/10.1182/blood-2021-150942
Published: 2021
Journal Articles

Targeting Glutamine Metabolism Overcomes Resistance to Targeted Therapies in Refractory Mantle Cell Lymphoma

Lingzhi Li, Changying Jiang, PhD, Lucy Jayne Navsaria, Yang Liu, PhD, Angela Leeming, Michael Wang, MD, Yixin Yao, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 25–26.
https://doi.org/10.1182/blood-2020-140736
Published: 2020
Journal Articles

Interrogation of Dysregulated Pathways Enables Precision Medicine in Mantle Cell Lymphoma

Yang Liu, PhD, Shuangtao Zhao, PhD, Changying Changying Jiang, PhD, Yixin Yao, PhD, Joseph McIntosh, BS, Alexa A Jordan, BS, Yijing Li, MS, Yuxuan Che, Preetesh Jain, MBBS,MDDM,PhD, Linghua Wang, PhD, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33.
https://doi.org/10.1182/blood-2020-140794
Published: 2020
Journal Articles

Abemaciclib-Based Combinational Therapies to Overcome Therapeutic Resistance in Mantle Cell Lymphoma

Yuxuan Che, Yang Liu, PhD, Lingzhi Li, Holly Hill, Joseph McIntosh, BS, Alexa A Jordan, BS, Dayoung Jung, Yixin Yao, PhD, Vivian Changying Jiang, PhD, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–34.
https://doi.org/10.1182/blood-2020-140856
Published: 2020
Journal Articles

Targeting the Synthetic Lethality Interaction of MTAP and PRMT5 to Overcome Drug Resistance and Enhance Anti-Cancer Immunity in Mantle Cell Lymphoma

Yixin Yao, PhD, Lingzhi Li, Yuxuan Che, Joseph McIntosh, BS, Holly Hill, Yang Liu, PhD, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 15.
https://doi.org/10.1182/blood-2020-138553
Published: 2020