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Journal Articles

Establishing a Pathogenic Role for NK Cells As Drivers of Bone Marrow Failure in the Myelodysplastic Syndromes (MDS)

Richa Rai, Jonathan Feld, Iyinyeloluwa Okulate, Stella Melana, Richard Sheppard, Erin Demakos, Shafinaz Hussein, Rachel Chen, Rachel Lee, Ronaldo de Real, Geoffrey Kelly, Brian Lee, Travis Dawson, Zhihong Chen, Vladimir Roudko, Seunghee kim-Schulze, Lewis R R. Silverman, Amir Horowitz
Journal: Blood
Blood (2023) 142 (Supplement 1): 4078.
https://doi.org/10.1182/blood-2023-181927
Published: 2023
Journal Articles

HSP27 Promotes Mantle Cell Lymphoma Growth and Mediates Resistance to Venetoclax

Yuxuan Che, Wei Wang, Yang Liu, Heng-Huan Lee, Yijing Li, Zhihong Chen, Joseph McIntosh, Changying Jiang, Yixin Yao, Michael Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 6405–6406.
https://doi.org/10.1182/blood-2022-167611
Published: 2022
Journal Articles

Targeting the HSP90-MYC-CDK9 Axis to Overcome Dual Resistance to BTK Inhibition and CAR-T Therapy in Mantle Cell Lymphoma

Vivian Changying Jiang, Fangfang Yan, Alexa A Jordan, Yuxuan Che, Yang Liu, Qingsong Cai, Yijing Li, Joseph McIntosh, Zhihong Chen, Jovanny Vargas, Yixin Yao, Heng-Huan Lee, Jingling Jin, Wei Wang, Lei Nie, Zhongming Zhao, Lukas M Simon, Michael L. Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 3512–3513.
https://doi.org/10.1182/blood-2022-163696
Published: 2022
Journal Articles

Single Cell Transcriptomic Profiling of Patient-Derived Xenografts of Mantle Cell Lymphoma Reveals a Special Tumor Cell Population: Seed Cells for Disease Dissemination and Progression

Vivian Changying Jiang, Qingsong Cai, Dapeng Hao, Yang Liu, Yijing Li, Yuxuan Che, Joseph McIntosh, Alexa A Jordan, Zhihong Chen, Angela Leeming, Lei Nie, Linghua Wang, Michael Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 1319.
https://doi.org/10.1182/blood-2021-149280
Published: 2021
Journal Articles

Abemaciclib in Combination with Copanlisib to Overcome Therapeutic Resistance in Mantle Cell Lymphoma

Yuxuan Che, Yang Liu, Yijing Li, Joseph McIntosh, Alexa A Jordan, Zhihong Chen, Fangfang Yan, Wei Wang, Jingling Jin, Changying Jiang, Yixin Yao, Michael Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 2253.
https://doi.org/10.1182/blood-2021-150942
Published: 2021
Journal Articles

Targeting ROR1 Using the Antibody Drug Conjugate Vls-101 in Aggressive Mantle Cell Lymphoma

Vivian Changying Jiang, PhD, Yang Liu, PhD, Joseph McIntosh, BS, Alexa A Jordan, BS, Angela Leeming, Zhihong Chen, Katti A. Jessen, PhD, Brian J. Lannutti, PhD, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33.
https://doi.org/10.1182/blood-2020-137660
Published: 2020
Journal Articles

Single Cell Transcriptomic Evolution and Resistance Mechanisms of BTK and BCL-2 Inhibition in Mantle Cell Lymphoma

Vivian Changying Jiang, PhD, Shaojun Zhang, PhD, Junwei Lian, PhD, Yuanxin Wang, Rongjia Zhang, Yang Liu, PhD, Joseph McIntosh, BS, Guangchun Han, Ruiping Wang, PhD, David Santos, Maria Badillo, MSN, RN, OCN, CCRP, Angela Leeming, Zhihong Chen, Kimberly Hartig, John Bigcal, Hun Lee, MD, Raphael Eric Steiner, MD, Jorge Enrique Romaguera, MD, Preetesh Jain, MBBS,MDDM,PhD, Krystle Nomie, PhD, Andy Futreal, Linghua Wang, MDPhDMS, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–34.
https://doi.org/10.1182/blood-2020-140882
Published: 2020
Journal Articles

Transcriptomic Heterogeneity and Clonal Evolution Associated with Therapeutic Resistance in Mantle Cell Lymphoma Revealed By Single Cell RNA-Seq

Changying Jiang, PhD, Shaojun Zhang, PhD, Yuanxin Wang, Rongjia Zhang, Yang Liu, MD, Joseph Mitchell McIntosh, Guangchun Han, PhD, Ruiping Wang, PhD, David Santos, Maria Badillo, Angela Leeming, Zhihong Chen, Kimberly Hartig, John Bigcal, Hun Ju Lee, Raphael E Steiner, MD, Jorge Enrique Romaguera, MD, Preetesh Jain, MBBS, MDDM, PhD, Krystle Nomie, PhD, Andy Futreal, PhD, Linghua Wang, PhD, Michael L. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5217.
https://doi.org/10.1182/blood-2019-129134
Published: 2019
Journal Articles

Tumor Microenvironment Molecular Signatures That Define Therapeutic Resistance in Mantle Cell Lymphoma

Krystle Nomie, PhD, Nikita Kotlov, PhD, Viktor Svekolkin, PhD, Alexander Bagaev, PhD, Qingsong Cai, PhD, Jasmine Falahat, Omar Moghrabi, Felix Frenkel, PhD, Ravshan Attaulakhanov, PhD, Angela Leeming, Dayoung Jung, Holly Hill, Kelley Paige Murfin, MSPH, Zhihong Chen, Kimberly Hartig, Maria Badillo, Preetesh Jain, MBBS,MDDM,PhD, Liang Zhang, MD PhD, Michael Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2762.
https://doi.org/10.1182/blood-2019-130512
Published: 2019
Journal Articles

Pre-Clinical Evaluation of the PI3K-p110β/δ Inhibitor KA2237 in Mantle Cell Lymphoma

Shengjian Huang, Loretta J. Nastoupil, MD, Hui Guo, MD PhD, Taylor Bell, Makhdum Ahmed, MD MPH, Carrie J Li, Jack Wang, Yang Liu, PhD, Victoria Zhang, Caroline R Kim, Jordan N Boyle, Elizabeth A Lorence, Laura T Lam, PhD, Zhihong Chen, Hui Zhang, Stephen Joseph Shuttleworth, PhD, Krystle Nomie, PhD, Michael Wang, MD, Liang Zhang, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1837.
https://doi.org/10.1182/blood.V128.22.1837.1837
Published: 2016
Journal Articles

Patient-Derived Xenograft Model in B-Cell Lymphoma: A Platform for a Personalized Clinical Trial

Taylor Bell, Hui Zhang, Makhdum Ahmed, MD MPH, Hui Guo, MD PhD, Carrie J Li, Yang Liu, PhD, Laura T Lam, PhD, Zhihong Chen, Jack Wang, Victoria Zhang, Krystle Nomie, PhD, Liang Zhang, MD PhD, Michael Wang, MD
Journal: Blood
Blood (2016) 128 (22): 1839.
https://doi.org/10.1182/blood.V128.22.1839.1839
Published: 2016