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Journal Articles

The Selective CDK9 Inhibitor VIP152 Overcame Therapeutic Resistance in Mantle Cell Lymphoma

William Lee, Vivian Changying Jiang, Tianci Zhang, Fangfang Yan, Qingsong Cai, Joseph McIntosh, Yang Liu, Michael L. Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 2821.
https://doi.org/10.1182/blood-2023-175035
Published: 2023
Journal Articles

The Reversible BTK Inhibitor Nemtabrutinib Demonstrates Favorable Antitumor Efficacy and Enhances the Function of CAR T Cells in Mantle Cell Lymphoma

Margaret Elizabeth Simmons, Joseph McIntosh, Tianci Zhang, Yijing Li, Fangfang Yan, Yixin Yao, Lei Nie, Heng-Huan Lee, Wei Wang, Vivian Changying Jiang, Michael Wang, Yang Liu
Journal: Blood
Blood (2023) 142 (Supplement 1): 5789.
https://doi.org/10.1182/blood-2023-187405
Published: 2023
Journal Articles

Predicting CAR-T Response in Mantle Cell Lymphoma Using Deep Neural Network Models on Single-Cell RNA Sequencing Data

Fangfang Yan, Vivian Changying Jiang, Yang Liu, Yijing Li, Yuxuan Che, Preetesh Jain, Lukas Simon, Michael Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 4377.
https://doi.org/10.1182/blood-2023-187544
Published: 2023
Journal Articles

Dual Targeting of ROR1 and BTK Augments the Anti-Lymphoma Activity in Mantle Cell Lymphoma

Lei Nie, Vivian Changying Jiang, Yang Liu, Joseph McIntosh, Jovanny Vargas, Qingsong Cai, Michael L. Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 4366.
https://doi.org/10.1182/blood-2023-189531
Published: 2023
Journal Articles

Targeting the HSP90-MYC-CDK9 Axis to Overcome Dual Resistance to BTK Inhibition and CAR-T Therapy in Mantle Cell Lymphoma

Vivian Changying Jiang, Fangfang Yan, Alexa A Jordan, Yuxuan Che, Yang Liu, Qingsong Cai, Yijing Li, Joseph McIntosh, Zhihong Chen, Jovanny Vargas, Yixin Yao, Heng-Huan Lee, Jingling Jin, Wei Wang, Lei Nie, Zhongming Zhao, Lukas M Simon, Michael L. Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 3512–3513.
https://doi.org/10.1182/blood-2022-163696
Published: 2022
Journal Articles

Establishment of Patient-Derived Organoid Culture Platform of Mantle Cell Lymphoma

Lei Nie, Yang Liu, Yuxuan Che, Yijing Li, Wei Wang, Jingling Jin, Qingsong Cai, Jovanny Vargas, Joseph McIntosh, Alexa A Jordan, Vivian Changying Jiang, Yixin Yao, Michael Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 3508.
https://doi.org/10.1182/blood-2021-152994
Published: 2021
Journal Articles

Single Cell Transcriptomic Profiling of Patient-Derived Xenografts of Mantle Cell Lymphoma Reveals a Special Tumor Cell Population: Seed Cells for Disease Dissemination and Progression

Vivian Changying Jiang, Qingsong Cai, Dapeng Hao, Yang Liu, Yijing Li, Yuxuan Che, Joseph McIntosh, Alexa A Jordan, Zhihong Chen, Angela Leeming, Lei Nie, Linghua Wang, Michael Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 1319.
https://doi.org/10.1182/blood-2021-149280
Published: 2021
Journal Articles

Combination Therapy of Bcl-2/X L dual Inhibitor AZD0466 with Acalabrutinib to Overcome Therapeutic Resistance in Aggressive R/R Mantle Cell Lymphoma

Yijing Li, Yang Liu, Yuxuan Che, Joseph McIntosh, Alexa A Jordan, Angela Leeming, Courtney L Andersen, Justin Cidado, Jingling Jin, Vivian Changying Jiang, Michael Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 1867.
https://doi.org/10.1182/blood-2021-151609
Published: 2021
Journal Articles

Dual Targeting Bcl-2 By Venetoclax and Mcl-1 By AZD5991 to Overcome Therapeutic Resistance in Aggressive R/R Mantle Cell Lymphoma

Yijing Li, Yang Liu, Yuxuan Che, Alexa A Jordan, Joseph McIntosh, Angela Leeming, Courtney L Andersen, Justin Cidado, Jingling Jin, Vivian Changying Jiang, Michael Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 1181.
https://doi.org/10.1182/blood-2021-151062
Published: 2021
Journal Articles

Oncogenic MALT1 Promotes Cell Survival and Mediates Ibrutinib Resistance and Ibrutinib-Venetoclax Resistance in Mantle Cell Lymphoma

Vivian Changying Jiang, PhD, Junwei Lian, PhD, Shengjian Huang, PhD, Shaojun Zhang, PhD, Yang Liu, PhD, Linghua Wang, MDPhDMS, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 18.
https://doi.org/10.1182/blood-2020-140871
Published: 2020
Journal Articles

Targeting Transcription Checkpoint Using a Novel CDK9 Inhibitor in Mantle Cell Lymphoma

Junwei Lian, PhD, Yu Xue, PhD, Alexa A Jordan, BS, Joseph McIntosh, BS, Yang Liu, PhD, Michael Wang, MD, Jia Zhou, PhD, Vivian Changying Jiang, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 28–29.
https://doi.org/10.1182/blood-2020-140865
Published: 2020
Journal Articles

Abemaciclib-Based Combinational Therapies to Overcome Therapeutic Resistance in Mantle Cell Lymphoma

Yuxuan Che, Yang Liu, PhD, Lingzhi Li, Holly Hill, Joseph McIntosh, BS, Alexa A Jordan, BS, Dayoung Jung, Yixin Yao, PhD, Vivian Changying Jiang, PhD, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–34.
https://doi.org/10.1182/blood-2020-140856
Published: 2020
Journal Articles

Targeting ROR1 Using the Antibody Drug Conjugate Vls-101 in Aggressive Mantle Cell Lymphoma

Vivian Changying Jiang, PhD, Yang Liu, PhD, Joseph McIntosh, BS, Alexa A Jordan, BS, Angela Leeming, Zhihong Chen, Katti A. Jessen, PhD, Brian J. Lannutti, PhD, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33.
https://doi.org/10.1182/blood-2020-137660
Published: 2020
Journal Articles

Overcoming CAR T Resistance with Non-Covalent BTK Inhibitor Loxo-305 in Mantle Cell Lymphoma

Yang Liu, PhD, Vivian Changying Jiang, PhD, Joseph McIntosh, BS, Alexa A Jordan, BS, Yijing Li, MS, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10.
https://doi.org/10.1182/blood-2020-137645
Published: 2020
Journal Articles

Single Cell Transcriptomic Evolution and Resistance Mechanisms of BTK and BCL-2 Inhibition in Mantle Cell Lymphoma

Vivian Changying Jiang, PhD, Shaojun Zhang, PhD, Junwei Lian, PhD, Yuanxin Wang, Rongjia Zhang, Yang Liu, PhD, Joseph McIntosh, BS, Guangchun Han, Ruiping Wang, PhD, David Santos, Maria Badillo, MSN, RN, OCN, CCRP, Angela Leeming, Zhihong Chen, Kimberly Hartig, John Bigcal, Hun Lee, MD, Raphael Eric Steiner, MD, Jorge Enrique Romaguera, MD, Preetesh Jain, MBBS,MDDM,PhD, Krystle Nomie, PhD, Andy Futreal, Linghua Wang, MDPhDMS, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–34.
https://doi.org/10.1182/blood-2020-140882
Published: 2020
Journal Articles

Xeno-MCL: Genomic, Transcriptomic and Pathologic Landscape Associated with Disease Progression, Clonal Evolution and Tissue Tropism in Patient-Derived Xenografts of Mantle Cell Lymphoma

Vivian Changying Jiang, PhD, Shaojun Zhang, PhD, Shuangtao Zhao, PhD, Yang Liu, PhD, Joseph McIntosh, BS, Linghua Wang, MDPhDMS, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 20.
https://doi.org/10.1182/blood-2020-140878
Published: 2020
Journal Articles

AZD4320 Is a Novel and Potent BCL-2/X L Dual Inhibitor in Targeting Aggressive Mantle Cell Lymphoma

Yijing Li, MS, Yang Liu, PhD, Joseph McIntosh, BS, Alexa A Jordan, BS, Angela Leeming, Courtney L Andersen, PhD, Justin Cidado, PhD, Vivian Changying Jiang, PhD, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 44.
https://doi.org/10.1182/blood-2020-140775
Published: 2020