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Journal Articles

A T-cell–based metric of immune age predicts outcomes in older patients with myeloma receiving daratumumab-based therapy

Available to Purchase
Wassilis S. C. Bruins, Febe Smits, Carolien Duetz, Kaz Groen, Charlotte L. B. M. Korst, A. Vera de Jonge, Christie P. M. Verkleij, Rosa Rentenaar, Meliha Cosovic, Merve Eken, Inoka Twickler, Paola M. Homan-Weert, Pieter Sonneveld, Philippe Moreau, Jürgen Claesen, Niels W. C. J. van de Donk, Sonja Zweegman, Tuna Mutis
Journal: Blood
Blood (2025) 146 (21): 2517–2530.
https://doi.org/10.1182/blood.2025028587
Published: 2025
Includes: Supplemental data
Journal Articles

Immune biomarkers of increased risk of infection in multiple myeloma (MM)

Free
Aintzane Zabaleta, Luis-Esteban Tamariz-Amador, Ioannis V. Kostopoulos, Romanos Sklavenitis-Pistofidis, Febe Smits, Carmen Roncal, Michelle Aranha, David Zihala, Michaela Machu, Nikolaos Tsakirakis, Panagiotis Bakouros, Ourania Tsitsilonis, Eirini Solia, Cristina Moreno, Catarina Maia, Esperanza Martin-Sanchez, José J. Perez, Cristina Encinas, Rafael Rios Tamayo, Albert Oriol, María-Jesús Blanchard, Felipe de Arriba, Esther González García, Sunil Lakhwani, Anna Sureda Balarí, Valentin Cabanas Perianes, Fernando Escalante Barrigón, Estrella Carrillo-Cruz, Albert Pérez-Montaña, Enrique Ocio, Joan Bargay, Alberto Orfao, Tomas Jelinek, Irene Ghobrial, Tuna Mutis, Sonja Zweegman, Evangelos Terpos, Efstathios Kastritis, Joaquin Martinez-Lopez, Juan-Jose Lahuerta Palacios, Carlos Fernandez de Larrea, Laura Rosiñol, Joan Batista Blade Creixenti, Paula Rodriguez-Otero, María-Victoria Mateos, Jesus San-Miguel, Maria Teresa Cedena Romero, Noemí Puig, Bruno Paiva
Journal: Blood
Blood (2025) 146 (Supplement 1): 365.
https://doi.org/10.1182/blood-2025-365
Published: 2025
Journal Articles

The bone marrow NK-cell profile predicts MRD negativity in patients with multiple myeloma treated with daratumumab-based therapy

Available to Purchase
Clinical Trials & Observations Brief Report
Charlotte L. B. M. Korst, Sabrin Tahri, Carolien Duetz, Wassilis S. C. Bruins, A. Vera de Jonge, Madelon E. de Jong, Cathelijne Fokkema, Febe Smits, Kaz Groen, Christie P. M. Verkleij, Kristine A. Frerichs, Natalie Papazian, Mark van Duin, Gregory van Beek, Remco Hoogenboezem, Thomas Baardemans, Giada Dal Collo, Elodie C. G. Stoetman, Meliha Cosovic, Inoka Twickler, Rosa Rentenaar, Merve Eken, Paola M. Homan-Weert, Elona Saraci, Mattia D’Agostino, Vincent H. J. van der Velden, Mathijs A. Sanders, Francesca Gay, Annemiek Broijl, Philippe Moreau, Pieter Sonneveld, Sonja Zweegman, Tuna Mutis, Tom Cupedo, Niels W. C. J. van de Donk
Journal: Blood
Blood (2025) 145 (25): 3007–3014.
https://doi.org/10.1182/blood.2024026455
Published: 2025
Includes: Supplemental data
Journal Articles

Beyond static measurements: dynamic frailty improves survival prediction in multiple myeloma

Available to Purchase
Clinical Trials & Observations
Febe Smits, Kaz Groen, Mark-David Levin, Claudia A. M. Stege, Roel van Kampen, Ellen van der Spek, Yavuz M. Bilgin, Noortje Thielen, Inger Nijhof, Inge Ludwig, Esther G. M. de Waal, Yorick Sandberg, Alain Kentos, Gert-Jan Timmers, Josien C. Regelink, Matthijs Westerman, Koen de Heer, Marie-Christiane Vekemans, Nazik Durdu-Rayman, Nicole C. H. P. de Graauw, Maarten R. Seefat, Niels W. C. J. van de Donk, Paula F. Ypma, Kazem Nasserinejad, Sonja Zweegman
Journal: Blood
Blood (2025) 145 (5): 543–546.
https://doi.org/10.1182/blood.2024025868
Published: 2025
Includes: Supplemental data
Journal Articles

Dynamics of Geriatric Impairments Are Associated with Risk of Treatment Discontinuation in Elderly Patients with Multiple Myeloma

Free
Febe Smits, Kazem Nasserinejad, Mark-David Levin, Gert Jan Timmers, Esther G.M. De Waal, Josien C Regelink, Gerjo A. Velders, Matthijs Westerman, Nazik Durdu-Rayman, Suzanne Last-Koopmans, Roel JW van Kampen, Claudia A M Stege, Kaz Groen, Maarten R. Seefat, Monique C. Minnema, Pieter Sonneveld, Paula F Ypma, Niels W.C.J. van de Donk, Sonja Zweegman
Journal: Blood
Blood (2024) 144 (Supplement 1): 3330.
https://doi.org/10.1182/blood-2024-203477
Published: 2024
Journal Articles

Frailty Subgroups Determine Heterogeneous Outcomes in Elderly Patients with Newly-Diagnosed Multiple Myeloma - Long-Term Follow-up of the HOVON 143 Trial

Free
Febe Smits, Kaz Groen, Mark-David Levin, Claudia A M Stege, Roel JW van Kampen, Ellen Van Der Spek, Yavuz M. Bilgin, Noortje Thielen, Inger S. Nijhof, Inge Ludwig, Esther G.M. De Waal, Yorick Sandberg, Alain Kentos, Gert Jan Timmers, Josien C Regelink, Matthijs Westerman, Koen de Heer, Marie Christiane Vekemans, Nazik Durdu-Rayman, Nicole de Graauw, Maarten R. Seefat, Niels W.C.J. van de Donk, Paula F Ypma, Kazem Nasserinejad, Sonja Zweegman
Journal: Blood
Blood (2024) 144 (Supplement 1): 4739.
https://doi.org/10.1182/blood-2024-208754
Published: 2024
Journal Articles

Dynamic Frailty Status Enables Better Prediction of Survival Probability - Results of the HOVON 143 Study

Free
Febe Smits, Kaz Groen, Mark-David Levin, Claudia Stege, Roel JW Van Kampen, Ellen Van Der Spek, Yavuz M Bilgin, Noortje Thielen, Inger S. Nijhof, Inge Ludwig, Esther G.M. De Waal, Yorick Sandberg, Alain Kentos, Gert Jan Timmers, Josien C Regelink, Matthijs Westerman, Koen de Heer, Marie Christiane Vekemans, Nazik Durdu-Rayman, Nicole de Graauw, Maarten R. Seefat, Niels WCJ van de Donk, Paula F Ypma, Kazem Nasserinejad, Sonja Zweegman
Journal: Blood
Blood (2023) 142 (Supplement 1): 342.
https://doi.org/10.1182/blood-2023-180006
Published: 2023