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Sabrin Tahri
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Journal Articles

Single-Cell Transcriptomic Analysis Reveals Reduction of Cytotoxic NK Cells in a Subset of Newly Diagnosed Multiple Myeloma Patients Impacting Outcome after Daratumumab Therapy

Sabrin Tahri, Madelon M.E. de Jong, Cathelijne Fokkema, Natalie Papazian, Zoltan Kellermayer, Michael Vermeulen, Mark van Duin, Pieter van de Woestijne, Kazem Nasserinejad, Elona Saraci, Mattia D'Agostino, Francesca Gay, Vincent H.J. van der Velden, Niels WCJ Van De Donk, Annemiek Broijl, Pieter Sonneveld, Sonja Zweegman, Tom Cupedo
Journal: Blood
Blood (2022) 140 (Supplement 1): 9982–9984.
https://doi.org/10.1182/blood-2022-164812
Published: 2022
Journal Articles

MAF Translocations Are Enriched in NDMM Patients with Elevated Levels of Circulating Tumor Cells Suggesting a Genetic Basis for Aggressive Disease Course

Cathelijne Fokkema, Madelon M.E. de Jong, Sabrin Tahri, Davine Hofste Op Bruinink, Zoltan Kellermayer, Chelsea den Hollander, Michael Vermeulen, Natalie Papazian, Mark van Duin, Remco Hoogenboezem, Michiel J.W. Wevers, Vincent H.J. van der Velden, Mathijs A. Sanders, Annemiek Broijl, Pieter Sonneveld, Tom Cupedo
Journal: Blood
Blood (2022) 140 (Supplement 1): 9917–9918.
https://doi.org/10.1182/blood-2022-166162
Published: 2022
Journal Articles

Single-Cell RNA-Sequencing Identifies Immune Biomarkers of Progression in Patients with High-Risk Smoldering Multiple Myeloma Treated with Immunotherapy

Romanos Sklavenitis-Pistofidis, Michelle P. Aranha, Nicholas J. Haradhvala, Shohreh Varmeh, Daniel Heilpern-Mallory, Ting Wu, Nang Kham Su, Elizabeth D. Lightbody, François Aguet, Oksana Zavidij, Sabrin Tahri, Tarek H. Mouhieddine, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2022) 140 (Supplement 1): 268–269.
https://doi.org/10.1182/blood-2022-168839
Published: 2022
Journal Articles

Stromal Cell-Activated Bone Marrow Neutrophils Provide BAFF in Newly Diagnosed and Treated Multiple Myeloma

Madelon M.E. de Jong, Cathelijne Fokkema, Natalie Papazian, Teddie van Heusden, Michael Vermeulen, Sabrin Tahri, Remco Hoogenboezem, Mark van Duin, Pieter van de Woestijne, Anton Langerak, Annemiek Broijl, Pieter Sonneveld, Tom Cupedo
Journal: Blood
Blood (2022) 140 (Supplement 1): 4181–4182.
https://doi.org/10.1182/blood-2022-166339
Published: 2022
Journal Articles

Inhibition of MICA and MICB Shedding Enhances Cytokine-Induced Memory-like NK Cell-Mediated Activity Against Multiple Myeloma

Sabrin Tahri, Nang Kham Su, Luisa Maria Lampe, Han Dong, Juliana Vergara Cadavid, Natalie Papazian, Amanda Cao, Jean-Baptiste Alberge, Lucas Ferrari de Andrade, Mahshid Rahmat, Yujia Shen, Rebecca Boiarsky, Laura Blanco, Bruno Paiva, Andreas Guenther, Gad Getz, Pieter Sonneveld, Tom Cupedo, Kai W. Wucherpfennig, Irene Ghobrial, Rizwan Romee
Journal: Blood
Blood (2022) 140 (Supplement 1): 4204–4206.
https://doi.org/10.1182/blood-2022-164811
Published: 2022
Journal Articles

Single-Cell RNA-Sequencing Identifies Immune Biomarkers of Response to Immunotherapy in Patients with High-Risk Smoldering Myeloma

Romanos Sklavenitis-Pistofidis, Ankit K. Dutta, Sylvia Ujwary, Robert A. Redd, Alexandra Savell, Léa Fléchon, François Aguet, Nicholas Haradhvala, Oksana Zavidij, Mark Bustoros, Sabrin Tahri, Tarek H Mouhieddine, Nang K. Su, Lily Ardente, Shankara Anand, Jacalyn Rosenblatt, Jeffrey A. Zonder, James J. Vredenburgh, Adam Boruchov, Manisha Bhutani, Saad Z. Usmani, Jeffrey V. Matous, Andrew J. Yee, Andrzej Jakubowiak, Claudia E. Paba-Prada, Julia Prescott, Jacob P. Laubach, Salomon Manier, Omar Nadeem, Paul G. Richardson, Ashraf Z. Badros, Lorenzo Trippa, Maria-Victoria Mateos, Gad Getz, Irene M. Ghobrial
Journal: Blood
Blood (2021) 138 (Supplement 1): 330.
https://doi.org/10.1182/blood-2021-147623
Published: 2021
Journal Articles

Clonal Hematopoiesis Is Associated with Increased Risk of Progression of Asymptomatic Waldenström Macroglobulinemia

Sabrin Tahri, Tarek H Mouhieddine, Robert A. Redd, Luisa Maria Lampe, Katarina Nillson, Nang Kham Su, Habib El-Khoury, Amin H Nassar, Elio Adib, Govind Bindra, Sarah Abou Alaiwi, Lorenzo Trippa, David P. Steensma, Jorge J. Castillo, Steven P. Treon, Irene M. Ghobrial, Adam S. Sperling
Journal: Blood
Blood (2021) 138 (Supplement 1): 2678.
https://doi.org/10.1182/blood-2021-149711
Published: 2021
Journal Articles

Inflammasome-Primed Myeloid Cells Maintain a Pro-Tumor Microenvironment in Multiple Myeloma

Madelon M.E. de Jong, Cathelijne Fokkema, Natalie Papazian, Sabrin Tahri, Zoltan Kellermayer, Michael Vermeulen, Mark van Duin, Pieter van de Woestijne, Annemiek Broyl, Pieter Sonneveld, Tom Cupedo
Journal: Blood
Blood (2021) 138 (Supplement 1): 2679.
https://doi.org/10.1182/blood-2021-150327
Published: 2021
Journal Articles

Clonal Hematopoiesis Prevalence Increases throughout Treatment of Newly Diagnosed Multiple Myeloma Patients

Tarek H. Mouhieddine, Chidimma Nzerem, Robert A. Redd, Andrew Dunford, Matthew Joseph Leventhal, Romanos Sklavenitis-Pistofidis, Sabrin Tahri, Habib El-Khoury, David P. Steensma, Benjamin L. Ebert, Robert J. Soiffer, Jonathan J Keats, Shaadi Mehr, Daniel Auclair, Adam S. Sperling, Chip Stewart, Gad Getz, Irene M. Ghobrial
Journal: Blood
Blood (2021) 138 (Supplement 1): 1091.
https://doi.org/10.1182/blood-2021-152025
Published: 2021
Journal Articles

Single-Cell Transcriptomic Analysis Reveals Loss of Activated Bone Marrow NK Cells in Multiple Myeloma Patients Which Associates with Disease Progression in Mice

Sabrin Tahri, Zoltan Kellermayer, Madelon M.E. de Jong, Natalie Papazian, Cathelijne Fokkema, Chelsea den Hollander, Pieter van de Woestijne, Mark van Duin, Annemiek Broijl, Pieter Sonneveld, Tom Cupedo
Journal: Blood
Blood (2021) 138 (Supplement 1): 1578.
https://doi.org/10.1182/blood-2021-150422
Published: 2021
Journal Articles

High Levels of Circulating Tumor Cells Are Associated with Increased Bone Marrow Proliferation in Newly Diagnosed Multiple Myeloma Patients

Cathelijne Fokkema, Madelon M.E. de Jong, Sabrin Tahri, Zoltan Kellermayer, Chelsea den Hollander, Michael Vermeulen, Natalie Papazian, Mark van Duin, Michiel J.W. Wevers, Mathijs A. Sanders, Vincent H.J. van der Velden, Pieter Sonneveld, Annemiek Broyl, Tom Cupedo
Journal: Blood
Blood (2021) 138 (Supplement 1): 1566.
https://doi.org/10.1182/blood-2021-145971
Published: 2021
Journal Articles

Single-Cell Multi-Omics in Human Clonal Hematopoiesis Reveals That DNMT3A R882 Mutations Perturb Early Progenitor States through Selective Hypomethylation

Anna S Nam, MD, Neville Dusaj, MS, Franco Izzo, PhD, Rekha Murali, MS, Tarek H Mouhieddine, MD, Robert M Myers, Jesus Sotelo, Salima Benbarche, PhD, Federico Gaiti, PhD, Sabrin Tahri, MD MSc, Omar Abdel-Wahab, MD, Irene M. Ghobrial, MD, Ronan Chaligne, PhD, Dan A. Landau, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1–2.
https://doi.org/10.1182/blood-2020-142574
Published: 2020
Journal Articles

Deciphering Clonal Evolution and Dissemination of Multiple Myeloma Cells In Vivo

Yujia Shen, PhD, Yuji Mishima, Jiantao Shi, PhD, Michele Moschetta, MD, Salomon Manier, MD PhD, Aldo M. Roccaro, MDPhD, Francois Mercier, MD FRCPC, Satoshi Takagi, PhD, Yawara Kawano, MD PhD, Shokichi Tsukamoto, MD PhD, Ilyas Sahin, Antonio Sacco, Daisy Huynh, MS, Brianna Berrios, BS, Romanos Pistofidis, MD, Jihye Park, PhD, Oksana Zavidij, PhD, Sabrin Tahri, MD, John G Doench, PhD, David E. Root, PhD, Franziska Michor, PhD, David T. Scadden, MD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 55.
https://doi.org/10.1182/blood-2018-99-113916
Published: 2018
Journal Articles

In Vivo Modeling of Clonal Competition Using CRISPR-Based Gene Editing Reveals Novel Fitness Variables in Multiple Myeloma

Yujia Shen, PhD, Salomon Manier, MD PhD, Sabrin Tahri, MD, Brianna Berrios, BS, Oksana Zavidij, PhD, Jihye Park, PhD, Romanos Pistofidis, MD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 57.
https://doi.org/10.1182/blood-2018-99-113842
Published: 2018
Journal Articles

In Vivo Genome-Wide Crispr Library Screen in a Xenograft Mouse Model of Tumor Growth and Metastasis of Multiple Myeloma

Yujia Shen, PhD, Salomon Manier, MD, Jihye Park, PhD, Yuji Mishima, PhD, Marzia Capelletti, PhD MMSc, Aldo M. Roccaro, MD PhD, Daisy Huynh, BS, MS, Antonio Sacco, BS, Sabrin Tahri, BS, Glenn Cowley, PhD, John G Doench, PhD, David Root, PhD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2016) 128 (22): 1137.
https://doi.org/10.1182/blood.V128.22.1137.1137
Published: 2016