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Journal Articles

3D Tissue-Engineered Bone Marrow Culture Predicts Patient Response to Drugs in Multiple Myeloma

Kinan Alhallak, Amanda Jeske, Pilar De La Puente, Jennifer Sun, Mark A. Fiala, Feda Azab, Barbara Muz, Ilyas Sahin, Ravi Vij, John F. DiPersio, Abdel Kareem Azab

Blood (2021) 138 (Supplement 1): 2690.

https://doi.org/10.1182/blood-2021-153832

Published: 2021

Journal Articles

Cerebrospinal Fluid (CSF) Analysis of Tumor-Specific Cell-Free DNA (cfDNA) As a Diagnostic and Prognostic Tool for Central Nervous System (CNS) Invasion in Lymphoma

Adam J Olszewski, MD, Anna D Chorzalska, PhD, Max Petersen, Thomas A Ollila, MD, Adam Zayac, MD, Habibe Kurt, MD, Diana O Treaba, MD, John L Reagan, MD, Andrew Hsu, MD, Pamela C Egan, MD, James Butera, MD, William Rafelson, MDMBA, Rabin Niroula, MBBS, John Vatkevich, Jordan Robison, CRA, Ilyas Sahin, MD, Chelsea D Mullins, BS, Patrycja M Dubielecka, PhD

Blood (2020) 136 (Supplement 1): 21–22.

https://doi.org/10.1182/blood-2020-134757

Published: 2020

Journal Articles

Erythrophagocytosis on bone marrow found in severe autoimmune hemolytic anemia with reticulocytopenia

Ilyas Sahin, Rabin Niroula

Blood (2019) 134 (21): 1877.

https://doi.org/10.1182/blood.2019002708

Published: 2019

Journal Articles

Recipients of Myelotoxic Chemotherapy Have Increased Prevalence of Clonal Hematopoiesis of Indeterminate Potential (CHIP) with a Typical Distribution of Chip-Associated Mutations

Adam J Olszewski, MD, Anna Dorota Chorzalska, PhD, Annette S. Kim, MD PhD, Peter J. Quesenberry, MD, Mary L Lopresti, DO, Mary Anne Fenton, MD, John L. Reagan, MD, James Butera, MD, Ilyas Sahin, MD, Celine Hamel, CRA, Jordan Robison, CRA, Max Petersen, Patrycja Dubielecka, PhD

Blood (2018) 132 (Supplement 1): 3841.

https://doi.org/10.1182/blood-2018-99-111436

Published: 2018

Journal Articles

Deciphering Clonal Evolution and Dissemination of Multiple Myeloma Cells In Vivo

Blood (2018) 132 (Supplement 1): 55.

https://doi.org/10.1182/blood-2018-99-113916

Published: 2018

Journal Articles

In Vivo Analysis of Clonal Evolution of Multiple Myeloma

Yuji Mishima, PhD, Jiantao Shi, PhD, Michele Moschetta, MD, Yujia Shen, PhD, Salomon Manier, MD, Aldo M. Roccaro, MD PhD, Francois Mercier, MD FRCPC, Satoshi Takagi, PhD, Yawara Kawano, MD PhD, Shokichi Tsukamoto, MD PhD, Ilyas Sahin, Antonio Sacco, BS, Kiyohiko Hatake, MD PhD, Franziska Michor, PhD, David T. Scadden, MD, Irene M. Ghobrial, MD

Blood (2016) 128 (22): 799.

https://doi.org/10.1182/blood.V128.22.799.799

Published: 2016

Journal Articles

Proline-Rich Tyrosine Kinase (Pyk2) Promotes Tumor Progression in Multiple Myeloma (MM) and Represents a Novel Target for Therapy in MM

Yu Zhang, MD, Yong Zhang, PhD, Yuji Mishima, PhD, Michele Moschetta, MD, Wenjing Zhang, MD, Patricia Maiso, PhD, Antonio Sacco, BS, Yosra Aljawai, MS, Ilyas Sahin, MD, Michaela R. Reagan, PhD, Jennifer E. Ring, Winnie F. Tam, PhD, Qunli Xu, PhD, Jonathan A. Pachter, PhD, Aldo M Roccaro, MD PhD, Irene M. Ghobrial, MD

Blood (2014) 124 (21): 2101.

https://doi.org/10.1182/blood.V124.21.2101.2101

Published: 2014

Journal Articles

Early Trafficking of Bone Marrow Derived-Endothelial Progenitor Cells Promotes Multiple Myeloma Progression

Michele Moschetta, MD, Yuji Mishima, PhD, Yawara Kawano, MD PhD, Yosra Aljawai, MS, Bruno Paiva, PhD, Luis Palomera, MD, Arianna Calcinotto, Unitt L. Christine, BSc, Ilyas Sahin, MD, Antonio Sacco, BS, Siobhan Glavey, MD, Michaela R. Reagan, PhD, Salomon Manier, MD, Peter Leif Bergsagel, MD PhD, Marta Chesi, PhD, Matteo Bellone, MD, Aldo M Roccaro, MD PhD, Irene M. Ghobrial, MD

Blood (2014) 124 (21): 4719.

https://doi.org/10.1182/blood.V124.21.4719.4719

Published: 2014

Journal Articles

Citron Rho-Interacting Serine/Threonine kinase (CIT) Is a Novel Therapeutic Target in Multiple Myeloma Cells

Yawara Kawano, MDPhD, Ilyas Sahin, MD, Michele Moschetta, MD, Jinhua Wang, Salomon Manier, MD, Siobhan Glavey, MD, Yuji Mishima, PhD, Katsutoshi Kokubun, PhD, Shokichi Tsukamoto, MD PhD, Antonio Sacco, BS, Kenneth C. Anderson, MD, Aldo M Roccaro, MD PhD, Nathanael S. Gray, PhD, Irene M. Ghobrial, MD

Blood (2014) 124 (21): 3430.

https://doi.org/10.1182/blood.V124.21.3430.3430

Published: 2014

Journal Articles

Pyk2 promotes tumor progression in multiple myeloma

Blood (2014) 124 (17): 2675–2686.

https://doi.org/10.1182/blood-2014-03-563981

Published: 2014

Includes: Supplemental data

Journal Articles

CXCR7-dependent angiogenic mononuclear cell trafficking regulates tumor progression in multiple myeloma

Abdel Kareem Azab, Ilyas Sahin, Feda Azab, Michele Moschetta, Yuji Mishima, Nicholas Burwick, Johann Zimmermann, Barbara Romagnoli, Kalpana Patel, Eric Chevalier, Aldo M. Roccaro, Irene M. Ghobrial

Blood (2014) 124 (12): 1905–1914.

https://doi.org/10.1182/blood-2014-02-558742

Published: 2014

Journal Articles

The sialyltransferase ST3GAL6 influences homing and survival in multiple myeloma

Siobhan V. Glavey, Salomon Manier, Alessandro Natoni, Antonio Sacco, Michele Moschetta, Michaela R. Reagan, Laura S. Murillo, Ilyas Sahin, Ping Wu, Yuji Mishima, Yu Zhang, Wenjing Zhang, Yong Zhang, Gareth Morgan, Lokesh Joshi, Aldo M. Roccaro, Irene M. Ghobrial, Michael E. O’Dwyer

Blood (2014) 124 (11): 1765–1776.

https://doi.org/10.1182/blood-2014-03-560862

Published: 2014

Includes: Supplemental data

Journal Articles

C1013G/CXCR4 acts as a driver mutation of tumor progression and modulator of drug resistance in lymphoplasmacytic lymphoma

Aldo M. Roccaro, Antonio Sacco, Cristina Jimenez, Patricia Maiso, Michele Moschetta, Yuji Mishima, Yosra Aljawai, Ilyas Sahin, Michelle Kuhne, Pina Cardarelli, Lewis Cohen, Jesus F. San Miguel, Ramon Garcia-Sanz, Irene M. Ghobrial

Blood (2014) 123 (26): 4120–4131.

https://doi.org/10.1182/blood-2014-03-564583

Published: 2014

Includes: Supplemental data

Journal Articles

Class I PI3K Isoforms Exert a Differential Role On Survival and Cell Trafficking In Multiple Myeloma

Ilyas Sahin, MD, Feda Azab, Michele Moschetta, MD, Yuji Mishima, PhD, Brian Tsang, Patricia Maiso, PhD, Antonio Sacco, BS, Aldo M Roccaro, MD, PhD, Abdel Kareem Azab, PhD, BSPharm, Irene M. Ghobrial, MD

Blood (2013) 122 (21): 3159.

https://doi.org/10.1182/blood.V122.21.3159.3159

Published: 2013

Journal Articles

CXCR4 Is a Regulator Of Disease Involvement Of Extramedullary Myeloma Confirmed By a Novel Mouse Model For Extramedullary Disease

Yuji Mishima, Ph. D., Michele Moschetta, MD, Michaela R Reagan, PhD, Yong Zhang, PhD, Ilyas Sahin, MD, Niraj Maulkhan, Aldo M Roccaro, MD, PhD, Irene M. Ghobrial, MD

Blood (2013) 122 (21): 5320.

https://doi.org/10.1182/blood.V122.21.5320.5320

Published: 2013

Journal Articles

Bone Marrow Mobilization Of Endothelial Progenitor Cells Represents An Early Pathogenic Event During Multiple Myeloma Progression

Michele Moschetta, MD, Yuji Mishima, PhD, Yosra Aljawai, MS, Ilyas Sahin, MD, Arianna Calcinotto, PhD, Salomon Manier, MD, Patricia Maiso, PhD, Antonio Sacco, BS, Matteo Bellone, MD, Aldo M Roccaro, MD, PhD, Irene M. Ghobrial, MD

Blood (2013) 122 (21): 680.

https://doi.org/10.1182/blood.V122.21.680.680

Published: 2013

Journal Articles

Mirna Expression Profiling and Proteomic Analysis Of Circulating Exosomes From Multiple Myeloma Patients

Salomon Manier, MD, Erica N Boswell, BS, Siobhan Glavey, MD, Antonio Sacco, BS, Patricia Maiso, PhD, Yuji Mishima, PhD, Yosra Aljaway, BS, Ranjit Banwait, MA, Wenjing Zhang, MD, Yu Zhang, MD, Ilyas Sahin, MD, Michele Moschetta, MD, Yong Zhang, PhD, Michaela R Reagan, PhD, John M. Asara, PhD, Xavier Leleu, MD, PhD, Aldo M Roccaro, MD, PhD, Irene M. Ghobrial, MD

Blood (2013) 122 (21): 3086.

https://doi.org/10.1182/blood.V122.21.3086.3086

Published: 2013

Journal Articles

Proline-Rich Tyrosine Kinase (Pyk2) Promotes Tumor Progression In Multiple Myeloma Through Modulation Of Wnt/β-Catenin Signaling Pathway

Yu Zhang, MD, Yong Zhang, PhD, Yuji Mishima, PhD, Michele Moschetta, MD, Wenjing Zhang, MD, Patricia Maiso, PhD, Antonio Sacco, BS, Yosra Aljawai, MS, Ilyas Sahin, MD, Michaela Reagan, PhD, Aldo M Roccaro, MD, PhD, Irene M. Ghobrial, MD

Blood (2013) 122 (21): 3094.

https://doi.org/10.1182/blood.V122.21.3094.3094

Published: 2013

Journal Articles

Silencing The Sialyltransferase Gene ST3GAL6 Inhibits Adhesion and Migration Of Myeloma Cells In Vitro and Reduces The Homing and Proliferation Of Tumor Cells In Vivo

Siobhan Glavey, MD, Salomon Manier, MD, Antonio Sacco, BS, Michaela R Reagan, PhD, Yuji Mishima, PhD, Yong Zhang, PhD, Ilyas Sahin, MD, Yu Zhang, MD, Wenjing Zhang, MD, Laura S Murillo, PhD, Catherine Loughrey, MSc, Alessandro Natoni, PhD, Katarzyna Kazlowska, Lokesh Joshi, PhD, Aldo M Roccaro, MD, PhD, Irene M. Ghobrial, MD, Michael E O'Dwyer, MD, FRCPI, FRCPath

Blood (2013) 122 (21): 275.

https://doi.org/10.1182/blood.V122.21.275.275

Published: 2013

Journal Articles

Lin28B/Let-7 Axis Regulates Multiple Myeloma Proliferation By Enhancing c-Myc and Ras Survival Pathways

Salomon Manier, MD, John T Powers, PhD, Antonio Sacco, BS, Michaela R Reagan, PhD, Michele Moschetta, MD, Siobhan Glavey, MD, Patricia Maiso, PhD, Ilyas Sahin, MD, Yuji Mishima, PhD, Yosra Aljaway, BS, Xavier Leleu, MD, PhD, Aldo M Roccaro, MD, PhD, George Q. Daley, MD, PhD, Irene M. Ghobrial, MD

Blood (2013) 122 (21): 273.

https://doi.org/10.1182/blood.V122.21.273.273

Published: 2013

NARROW

3D Tissue-Engineered Bone Marrow Culture Predicts Patient Response to Drugs in Multiple Myeloma

Cerebrospinal Fluid (CSF) Analysis of Tumor-Specific Cell-Free DNA (cfDNA) As a Diagnostic and Prognostic Tool for Central Nervous System (CNS) Invasion in Lymphoma

Erythrophagocytosis on bone marrow found in severe autoimmune hemolytic anemia with reticulocytopenia

Recipients of Myelotoxic Chemotherapy Have Increased Prevalence of Clonal Hematopoiesis of Indeterminate Potential (CHIP) with a Typical Distribution of Chip-Associated Mutations

Deciphering Clonal Evolution and Dissemination of Multiple Myeloma Cells In Vivo

In Vivo Analysis of Clonal Evolution of Multiple Myeloma

Proline-Rich Tyrosine Kinase (Pyk2) Promotes Tumor Progression in Multiple Myeloma (MM) and Represents a Novel Target for Therapy in MM

Early Trafficking of Bone Marrow Derived-Endothelial Progenitor Cells Promotes Multiple Myeloma Progression

Citron Rho-Interacting Serine/Threonine kinase (CIT) Is a Novel Therapeutic Target in Multiple Myeloma Cells

Pyk2 promotes tumor progression in multiple myeloma

CXCR7-dependent angiogenic mononuclear cell trafficking regulates tumor progression in multiple myeloma

The sialyltransferase ST3GAL6 influences homing and survival in multiple myeloma

C1013G/CXCR4 acts as a driver mutation of tumor progression and modulator of drug resistance in lymphoplasmacytic lymphoma

Class I PI3K Isoforms Exert a Differential Role On Survival and Cell Trafficking In Multiple Myeloma

CXCR4 Is a Regulator Of Disease Involvement Of Extramedullary Myeloma Confirmed By a Novel Mouse Model For Extramedullary Disease

Bone Marrow Mobilization Of Endothelial Progenitor Cells Represents An Early Pathogenic Event During Multiple Myeloma Progression

Mirna Expression Profiling and Proteomic Analysis Of Circulating Exosomes From Multiple Myeloma Patients

Proline-Rich Tyrosine Kinase (Pyk2) Promotes Tumor Progression In Multiple Myeloma Through Modulation Of Wnt/β-Catenin Signaling Pathway

Silencing The Sialyltransferase Gene ST3GAL6 Inhibits Adhesion and Migration Of Myeloma Cells In Vitro and Reduces The Homing and Proliferation Of Tumor Cells In Vivo

Lin28B/Let-7 Axis Regulates Multiple Myeloma Proliferation By Enhancing c-Myc and Ras Survival Pathways

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American Society of Hematology

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American Society of Hematology

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