1-12 of 12
Winnie F. Tam
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

VS-4718, a Potent Focal Adhesion Kinase (FAK) Inhibitor, Exhibits Anticancer Activity in Leukemia Models in Vitro and in Vivo

Winnie F. Tam, PhD, Jennifer E. Ring, Anthony F. Trombino, PhD, David T. Weaver, PhD, Jonathan A. Pachter, PhD, Mahesh Padval, PhD, Qunli Xu, PhD
Journal: Blood
Blood (2014) 124 (21): 982.
https://doi.org/10.1182/blood.V124.21.982.982
Published: 2014
Journal Articles

Proline-Rich Tyrosine Kinase (Pyk2) Promotes Tumor Progression in Multiple Myeloma (MM) and Represents a Novel Target for Therapy in MM

Yu Zhang, MD, Yong Zhang, PhD, Yuji Mishima, PhD, Michele Moschetta, MD, Wenjing Zhang, MD, Patricia Maiso, PhD, Antonio Sacco, BS, Yosra Aljawai, MS, Ilyas Sahin, MD, Michaela R. Reagan, PhD, Jennifer E. Ring, Winnie F. Tam, PhD, Qunli Xu, PhD, Jonathan A. Pachter, PhD, Aldo M Roccaro, MD PhD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2014) 124 (21): 2101.
https://doi.org/10.1182/blood.V124.21.2101.2101
Published: 2014
Journal Articles

Pyk2 promotes tumor progression in multiple myeloma

Yu Zhang, Michele Moschetta, Daisy Huynh, Yu-Tzu Tai, Yong Zhang, Wenjing Zhang, Yuji Mishima, Jennifer E. Ring, Winnie F. Tam, Qunli Xu, Patricia Maiso, Michaela Reagan, Ilyas Sahin, Antonio Sacco, Salomon Manier, Yosra Aljawai, Siobhan Glavey, Nikhil C. Munshi, Kenneth C. Anderson, Jonathan Pachter, Aldo M. Roccaro, Irene M. Ghobrial
Journal: Blood
Blood (2014) 124 (17): 2675–2686.
https://doi.org/10.1182/blood-2014-03-563981
Published: 2014
Includes: Supplemental data
Journal Articles

Adenosine A2A receptor agonists and PDE inhibitors: a synergistic multitarget mechanism discovered through systematic combination screening in B-cell malignancies

Richard J. Rickles, Laura T. Pierce, Thomas P. Giordano, 3rd, Winnie F. Tam, Douglas W. McMillin, Jake Delmore, Jacob P. Laubach, Alexis A. Borisy, Paul G. Richardson, Margaret S. Lee
Journal: Blood
Blood (2010) 116 (4): 593–602.
https://doi.org/10.1182/blood-2009-11-252668
Published: 2010
Includes: Supplemental data
Journal Articles

A2A or Beta-2 Adrenergic Receptor Agonist Synergies Induce Distinct Patterns of Gene Expression Relevant to Multiple Myeloma Cell Survival.

Winnie F. Tam, PhD, Richard J Rickles, PhD, Thomas Giordano, Alexis Borisy, Margaret S. Lee, PhD
Journal: Blood
Blood (2009) 114 (22): 3831.
https://doi.org/10.1182/blood.V114.22.3831.3831
Published: 2009
Journal Articles

Adenosine A2A and Beta-2 Adrenergic Receptor Agonist Synergy in B-Cell Malignancies: Selectivity, Breadth of Activity and Effects of Chronic Exposure.

Richard J. Rickles, PhD, Winnie F. Tam, PhD, Antoaneta Necheva, MSc, Thomas Giordano, Alexis A. Borisy, Margaret S. Lee, PhD
Journal: Blood
Blood (2009) 114 (22): 3762.
https://doi.org/10.1182/blood.V114.22.3762.3762
Published: 2009
Journal Articles

Adenosine A2A Receptor Agonism and PDE Inhibition: A Synergistic Multi-Target Mechanism Discovered through Systematic Combination Screening in Multiple Myeloma

Richard J Rickles, Ph.D., Laura Pierce, Thomas Giordano, Winnie F. Tam, Ph.D., Douglas W. McMillin, BSc, PhD, Kenneth C. Anderson, MD, Constantine Mitsiades, M.D., Ph.D., Margaret S Lee, Ph.D
Journal: Blood
Blood (2008) 112 (11): 847.
https://doi.org/10.1182/blood.V112.11.847.847
Published: 2008
Journal Articles

Adenosine A2A and Beta-2 Adrenergic Receptor Agonism: Novel Selective and Synergistic Multiple Myeloma Targets Discovered through Systematic Combination Screening

Richard J. Rickles, Ph.D., Laura Pierce, Thomas Giordano, Winnie F. Tam, Ph.D., William Avery, Melissa Farwell, David Crowe, Mei Chen, Ph.D., Alexander Brown, Vikram Kansra, PhD, Steffan T. Nawrocki, PhD, Jennifer S Carew, Ph.D., Francis J Giles, MD, Margaret S Lee, PhD
Journal: Blood
Blood (2008) 112 (11): 384.
https://doi.org/10.1182/blood.V112.11.384.384
Published: 2008
Journal Articles

Preclinical Evaluation of CRx-501, a Potent Selective A2A Agonist as a Novel Drug Candidate for the Treatment of Multiple Myeloma

Richard J Rickles, Ph.D., Laura Pierce, Thomas Giordano, William Avery, Melissa Farwell, David Crowe, Winnie F. Tam, Ph.D., Mei Chen, Ph.D., Vikram Kansra, PhD, Douglas W. McMillin, BSc, PhD, Kenneth C Anderson, MD, Constantine Mitsiades, M.D., Ph.D., Margaret S. Lee, PhD
Journal: Blood
Blood (2008) 112 (11): 252.
https://doi.org/10.1182/blood.V112.11.252.252
Published: 2008
Journal Articles

Id1 is a common downstream target of oncogenic tyrosine kinases in leukemic cells

Winnie F. Tam, Ting-Lei Gu, Jing Chen, Benjamin H. Lee, Lars Bullinger, Stefan Fröhling, Andrew Wang, Stefano Monti, Todd R. Golub, D. Gary Gilliland
Journal: Blood
Blood (2008) 112 (5): 1981–1992.
https://doi.org/10.1182/blood-2007-07-103010
Published: 2008
Includes: Supplemental data
Journal Articles

FLT3-ITD Cooperates with MOZ-TIF2 in Leukemogenesis in a Murine Bone Marrow Transplantation Model.

Winnie F. Tam, PhD, Jennifer Rocnik, Ph.D., Sarah Wojiski, Ph.D., Kenji Deguchi, M.D., Rachel Okabe, B.S., Ben Lee, M.D. Ph.D., D. Gary Gilliland, Ph.D. M.D.
Journal: Blood
Blood (2006) 108 (11): 1427.
https://doi.org/10.1182/blood.V108.11.1427.1427
Published: 2006
Journal Articles

Oncogenic Tyrosine Kinases Regulate Proliferative and Survival Signals through Activation of Id1.

Ting-Lei Gu, M.D./Ph.D., Winnie F. Tam, Ph.D., Jing Chen, Ph.D., Benjamin H. Lee, M.D./Ph.D, Andrew Z. Wang, M.D., Michael R. Cooper, M.D., Stefano Monti, Ph.D., Todd Golub, M.D., Gary D. Gilliland, Ph.D./M.D.
Journal: Blood
Blood (2004) 104 (11): 417.
https://doi.org/10.1182/blood.V104.11.417.417
Published: 2004