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Journal Articles

Genetically-Defined Diffuse Large B-Cell Lymphoma Subsets Arise By Distinct Pathogenetic Mechanisms and Predict Outcome

Bjoern Chapuy, MD PhD, Chip Stewart, PhD, Andrew Dunford, MS, Jaegil Kim, PhD, Atanas Kamburow, PhD, Robert A. Redd, MS, Michael Lawrence, PhD, Margaretha G.M. Roemer, MSc, Amy Li, Marita Ziepert, PhD, Annette M. Staiger, PhD, Jeremiah Wala, Matthew D. Ducar, MS, Ignaty Leshchiner, PhD, Esther Rheinbay, PhD, Amaro Taylor-Weiner, BS, Caroline Coughlin, BS, Julian Hess, Chandra Pedamallu, Dimitri Livitz, Daniel Rosebrock, Mara Rosenberg, Adam Tracy, Heike Horn, Paul van Hummelen, Andrew L Feldman, MD, Brian K Link, MD, Anne J Novak, PhD, James R. Cerhan, MD PhD, Thomas M Habermann, MD, Reiner Siebert, PhD, Andreas Rosenwald, Aaron R. Thorner, PhD, Matthew Meyerson, MDPhD, Todd R. Golub, MD, Rameen Beroukhim, Gerald Wulf, MD, German Ott, MD, Scott J. Rodig, MDPhD, Stefano Monti, PhD, Donna S. Neuberg, ScD, Markus Loeffler, MD, Michael Pfreundschuh, MD, Lorenz Trümper, MD, Gad Getz, PhD, Margaret A. Shipp, MD

Blood (2017) 130 (Supplement 1): 38.

https://doi.org/10.1182/blood.V130.Suppl_1.38.38

Published: 2017

Journal Articles

Diffuse large B-cell lymphoma patient-derived xenograft models capture the molecular and biological heterogeneity of the disease

Blood (2016) 127 (18): 2203–2213.

https://doi.org/10.1182/blood-2015-09-672352

Published: 2016

Includes: Supplemental data

Journal Articles

Targetable genetic features of primary testicular and primary central nervous system lymphomas

Blood (2016) 127 (7): 869–881.

https://doi.org/10.1182/blood-2015-10-673236

Published: 2016

Includes: Supplemental data

Journal Articles

Resolving the Biological Heterogeneity of B-Cell Lymphoma, Unclassifiable, with Features Intermediate Between DLBCL and BL (BCL-U) Using Quantitative Profiles of Oncogenic Signaling Networks

Christopher Daniel Carey, MD,, Daniel Gusenleitner, MS, Zhang Xuan, BA, Aliyah R Sohani, MD, Olga Weinberg, MD, Hongbo Yu, MD, Ben Chen, MD PhD, Bruce Woda, MD, Kai Fu, MD PhD, Stefano Monti, PhD, Scott J. Rodig, MD, PhD

Blood (2015) 126 (23): 3903.

https://doi.org/10.1182/blood.V126.23.3903.3903

Published: 2015

Journal Articles

Comprehensive Analyses of Genetic Features Identify Coordinate Signatures in Diffuse Large B-Cell Lymphoma

Blood (2015) 126 (23): 3922.

https://doi.org/10.1182/blood.V126.23.3922.3922

Published: 2015

Journal Articles

Diffuse Large B-Cell Lymphoma Patient-Derived Xenograft Models Capture Molecular and Biologic Heterogeneity and Inform Therapy

Blood (2015) 126 (23): 817.

https://doi.org/10.1182/blood.V126.23.817.817

Published: 2015

Journal Articles

Actionable Genetic Features of Primary Testicular and Primary Central Nervous System Lymphomas

Blood (2014) 124 (21): 74.

https://doi.org/10.1182/blood.V124.21.74.74

Published: 2014

Journal Articles

Disruption Of Super Enhancer-Driven Cancer Dependencies In Diffuse Large B-Cell Lymphoma

Bjoern Chapuy, MD, PhD, McKeown Michael, Charles Y. Lin, PhD, Stefano Monti, PhD, Margaretha GM Roemer, Jun Qi, Peter B. Rahl, PhD, Heather Sun, Kelly T. Yeda, Andrew L. Kung, MD, PhD, Scott J. Rodig, MD, PhD, Richard A. Young, PhD, Margaret A. Shipp, MD, James E. Bradner, MD

Blood (2013) 122 (21): 3021.

https://doi.org/10.1182/blood.V122.21.3021.3021

Published: 2013

Journal Articles

Preclinical Analyses Of The Chemical JAK2 Inhibitor, SAR302503, In Classical Hodgkin Lymphoma and Primary Mediastinal Large B-Cell Lymphoma

Yansheng Hao, MD, PhD, Bjoern Chapuy, MD, PhD, Stefano Monti, PhD, Heather Sun, Scott J. Rodig, MD, PhD, Margaret A Shipp, MD

Blood (2013) 122 (21): 4230.

https://doi.org/10.1182/blood.V122.21.4230.4230

Published: 2013

Journal Articles

CXCR4 Upregulation Is a Biomarker Of Sensitivity To Targeted Inhibition Of B-Cell Receptor Signaling In Diffuse Large B-Cell Lymphoma

Linfeng Chen, PhD, Yansheng Hao, MD, PhD, Jing Ouyang, PhD, Bjoern Chapuy, MD, PhD, Donna S. Neuberg, ScD, Thomas M Habermann, MD, Przemyslaw Juszczynski, MD, PhD, Scott J Rodig, MD, PhD, Stefano Monti, PhD, Margaret A Shipp, MD

Blood (2013) 122 (21): 631.

https://doi.org/10.1182/blood.V122.21.631.631

Published: 2013

Journal Articles

The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation

Blood (2013) 122 (3): 376–385.

https://doi.org/10.1182/blood-2012-11-466722

Published: 2013

Includes: Supplemental data

Journal Articles

A Structural Basis for p53-Deficiency, Deregulated Cell Cycle and Unfavorable Outcome in Diffuse Large B-Cell Lymphoma

Bjoern Chapuy, MD, PhD, Stefano Monti, PhD, Kunihiko Takeyama, MD, PhD, Scott J Rodig, MD, PhD, Yansheng Hao, MD, PhD, Kelly T Yeda, Haig Inguilizian, MD, Craig Mermel, Treeve Currie, Ahmet Dogan, MD, PhD, Jeffery Kutok, MD, PhD, Rameen Beroukhim, MD, PhD, Donna S. Neuberg, ScD, Thomas M Habermann, MD, Gad Getz, PhD, Andrew L. Kung, MD, PhD, Todd R. Golub, MD, Margaret A. Shipp, MD

Blood (2012) 120 (21): 1534.

https://doi.org/10.1182/blood.V120.21.1534.1534

Published: 2012

Journal Articles

Viral induction and targeted inhibition of galectin-1 in EBV + posttransplant lymphoproliferative disorders

Jing Ouyang, Przemyslaw Juszczynski, Scott J. Rodig, Michael R. Green, Evan O'Donnell, Treeve Currie, Myriam Armant, Kunihiko Takeyama, Stefano Monti, Gabriel A. Rabinovich, Jerome Ritz, Jeffery L. Kutok, Margaret A. Shipp

Blood (2011) 117 (16): 4315–4322.

https://doi.org/10.1182/blood-2010-11-320481

Published: 2011

Includes: Supplemental data

Journal Articles

Mir-15a/16-1 Cluster Is Frequently Deleted In Primary Hodgkin Lymphoma and Modulates Multiple Survival Pathways Including AP-1

Bjoern Chapuy, MD, PhD, Michael R Green, PhD, Jun Lu, PhD, Stefano Monti, PhD, Yansheng Hao, MD, PhD, Kelly T Yeda, Scott J Rodig, Treeve Currie, Kunihiko Takeyama, MD, PhD, Todd R Golub, MD, PhD, Jeffery Kutok, MD, PhD, Margaret A. Shipp, MD

Blood (2010) 116 (21): 746.

https://doi.org/10.1182/blood.V116.21.746.746

Published: 2010

Journal Articles

Integrative Analysis Reveals Multiple Alterations of p53 Signaling Pathway Components In Primary Diffuse Large B-Cell Lymphomas

Bjoern Chapuy, MD, PhD, Stefano Monti, PhD, Kunihiko Takeyama, MD, PhD, Gad Getz, Scott J Rodig, Jeffery Kutok, MD, PhD, Todd R Golub, Margaret A. Shipp, MD

Blood (2010) 116 (21): 635.

https://doi.org/10.1182/blood.V116.21.635.635

Published: 2010

Journal Articles

Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma

Michael R. Green, Stefano Monti, Scott J. Rodig, Przemyslaw Juszczynski, Treeve Currie, Evan O'Donnell, Bjoern Chapuy, Kunihiko Takeyama, Donna Neuberg, Todd R. Golub, Jeffery L. Kutok, Margaret A. Shipp

Blood (2010) 116 (17): 3268–3277.

https://doi.org/10.1182/blood-2010-05-282780

Published: 2010

Includes: Supplemental data

Journal Articles

Expression and Targeted Inhibition of the Immunoregulatory Carbohydrate-Binding Lectin, Galectin 1, in EBV-Driven Post-Transplant Lymphoproliferative Disorders.

Jing Ouyang, PhD, Przemyslaw Juszczynski, MD, PhD, Evan O'Donnell, Myriam Armant, PhD, Scott J. Rodig, MD, PhD, Kunihiko Takeyama, MD, PhD, Stefano Monti, PhD, Gabriel Rabinovich, PhD, Jeffery Lorne Kutok, MD, PhD, Jerome Ritz, MD, Margaret A. Shipp, MD

Blood (2009) 114 (22): 96.

https://doi.org/10.1182/blood.V114.22.96.96

Published: 2009

Journal Articles

Id1 is a common downstream target of oncogenic tyrosine kinases in leukemic cells

Winnie F. Tam, Ting-Lei Gu, Jing Chen, Benjamin H. Lee, Lars Bullinger, Stefan Fröhling, Andrew Wang, Stefano Monti, Todd R. Golub, D. Gary Gilliland

Blood (2008) 112 (5): 1981–1992.

https://doi.org/10.1182/blood-2007-07-103010

Published: 2008

Includes: Supplemental data

Journal Articles

SYK-dependent tonic B-cell receptor signaling is a rational treatment target in diffuse large B-cell lymphoma

Linfeng Chen, Stefano Monti, Przemyslaw Juszczynski, John Daley, Wen Chen, Thomas E. Witzig, Thomas M. Habermann, Jeffery L. Kutok, Margaret A. Shipp

Blood (2008) 111 (4): 2230–2237.

https://doi.org/10.1182/blood-2007-07-100115

Published: 2008

Includes: Supplemental data

Journal Articles

Lesional gene expression profiling in cutaneous T-cell lymphoma reveals natural clusters associated with disease outcome

Jessica Shin, Stefano Monti, Daniel J. Aires, Madeleine Duvic, Todd Golub, David A. Jones, Thomas S. Kupper

Blood (2007) 110 (8): 3015–3027.

https://doi.org/10.1182/blood-2006-12-061507

Published: 2007

NARROW

Genetically-Defined Diffuse Large B-Cell Lymphoma Subsets Arise By Distinct Pathogenetic Mechanisms and Predict Outcome

Diffuse large B-cell lymphoma patient-derived xenograft models capture the molecular and biological heterogeneity of the disease

Targetable genetic features of primary testicular and primary central nervous system lymphomas

Resolving the Biological Heterogeneity of B-Cell Lymphoma, Unclassifiable, with Features Intermediate Between DLBCL and BL (BCL-U) Using Quantitative Profiles of Oncogenic Signaling Networks

Comprehensive Analyses of Genetic Features Identify Coordinate Signatures in Diffuse Large B-Cell Lymphoma

Diffuse Large B-Cell Lymphoma Patient-Derived Xenograft Models Capture Molecular and Biologic Heterogeneity and Inform Therapy

Actionable Genetic Features of Primary Testicular and Primary Central Nervous System Lymphomas

Disruption Of Super Enhancer-Driven Cancer Dependencies In Diffuse Large B-Cell Lymphoma

Preclinical Analyses Of The Chemical JAK2 Inhibitor, SAR302503, In Classical Hodgkin Lymphoma and Primary Mediastinal Large B-Cell Lymphoma

CXCR4 Upregulation Is a Biomarker Of Sensitivity To Targeted Inhibition Of B-Cell Receptor Signaling In Diffuse Large B-Cell Lymphoma

The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation

A Structural Basis for p53-Deficiency, Deregulated Cell Cycle and Unfavorable Outcome in Diffuse Large B-Cell Lymphoma

Viral induction and targeted inhibition of galectin-1 in EBV + posttransplant lymphoproliferative disorders

Mir-15a/16-1 Cluster Is Frequently Deleted In Primary Hodgkin Lymphoma and Modulates Multiple Survival Pathways Including AP-1

Integrative Analysis Reveals Multiple Alterations of p53 Signaling Pathway Components In Primary Diffuse Large B-Cell Lymphomas

Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma

Expression and Targeted Inhibition of the Immunoregulatory Carbohydrate-Binding Lectin, Galectin 1, in EBV-Driven Post-Transplant Lymphoproliferative Disorders.

Id1 is a common downstream target of oncogenic tyrosine kinases in leukemic cells

SYK-dependent tonic B-cell receptor signaling is a rational treatment target in diffuse large B-cell lymphoma

Lesional gene expression profiling in cutaneous T-cell lymphoma reveals natural clusters associated with disease outcome

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American Society of Hematology

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American Society of Hematology

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