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Margaretha G. M. Roemer
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Journal Articles

Spatial signatures identify immune escape via PD-1 as a defining feature of T-cell/histiocyte-rich large B-cell lymphoma

Gabriel K. Griffin, Jason L. Weirather, Margaretha G. M. Roemer, Mikel Lipschitz, Alyssa Kelley, Pei-Hsuan Chen, Daniel Gusenleitner, Erin Jeter, Christine Pak, Evisa Gjini, Bjoern Chapuy, Michael H. Rosenthal, Jie Xu, Benjamin J. Chen, Aliyah R. Sohani, Scott B. Lovitch, Jeremy S. Abramson, Jeffrey J. Ishizuka, Austin I. Kim, Caron A. Jacobson, Ann S. LaCasce, Christopher D. Fletcher, Donna Neuberg, Gordon J. Freeman, F. Stephen Hodi, Kyle Wright, Azra H. Ligon, Eric D. Jacobsen, Philippe Armand, Margaret A. Shipp, Scott J. Rodig
Journal: Blood
Blood (2021) 137 (10): 1353–1364.
https://doi.org/10.1182/blood.2020006464
Published: 2021
Includes: Supplemental data
Journal Articles

Chromosome 20 loss is characteristic of breast implant–associated anaplastic large cell lymphoma

CME Clinical Trials & Observations Brief Report
G. Tjitske Los-de Vries, Mintsje de Boer, Erik van Dijk, Phylicia Stathi, Nathalie J. Hijmering, Margaretha G. M. Roemer, Matias Mendeville, Daniel M. Miedema, Jan Paul de Boer, Hinne A. Rakhorst, Flora E. van Leeuwen, René R. W. J. van der Hulst, Bauke Ylstra, Daphne de Jong
Journal: Blood
Blood (2020) 136 (25): 2927–2932.
https://doi.org/10.1182/blood.2020005372
Published: 2020
Includes: Supplemental data
Journal Articles

High frequency of inactivating tetraspanin C D37 mutations in diffuse large B-cell lymphoma at immune-privileged sites

Brief Report
Suraya Elfrink, Charlotte M. de Winde, Michiel van den Brand, Madeleine Berendsen, Margaretha G. M. Roemer, Frank Arnold, Luuk Janssen, Alie van der Schaaf, Erik Jansen, Patricia J. T. A. Groenen, Astrid Eijkelenboom, Wendy Stevens, Corine J. Hess, J. Han van Krieken, Joost S. P. Vermaat, Arjen H. G. Cleven, Ruben A. L. de Groen, Viviana Neviani, Daphne de Jong, Sjoerd van Deventer, Blanca Scheijen, Annemiek B. van Spriel
Journal: Blood
Blood (2019) 134 (12): 946–950.
https://doi.org/10.1182/blood.2019001185
Published: 2019
Includes: Supplemental data
Journal Articles

Aggressive genomic features in clinically indolent primary HHV8-negative effusion-based lymphoma

Matias Mendeville, Margaretha G. M. Roemer, Mari F. C. M. van den Hout, G. Tjitske Los-de Vries, Reno Bladergroen, Phylicia Stathi, Nathalie J. Hijmering, Andreas Rosenwald, Bauke Ylstra, Daphne de Jong
Journal: Blood
Blood (2019) 133 (4): 377–380.
https://doi.org/10.1182/blood-2017-12-822171
Published: 2019
Includes: Supplemental data
Journal Articles

Topological analysis reveals a PD-L1-associated microenvironmental niche for Reed-Sternberg cells in Hodgkin lymphoma

Christopher D. Carey, Daniel Gusenleitner, Mikel Lipschitz, Margaretha G. M. Roemer, Edward C. Stack, Evisa Gjini, Xihao Hu, Robert Redd, Gordon J. Freeman, Donna Neuberg, F. Stephen Hodi, Xiaole Shirley Liu, Margaret A. Shipp, Scott J. Rodig
Journal: Blood
Blood (2017) 130 (22): 2420–2430.
https://doi.org/10.1182/blood-2017-03-770719
Published: 2017
Includes: Supplemental data
Journal Articles

PD-1 blockade with nivolumab in relapsed/refractory primary central nervous system and testicular lymphoma

Clinical Trials & Observations Brief Report
Lakshmi Nayak, Fabio M. Iwamoto, Ann LaCasce, Srinivasan Mukundan, Margaretha G. M. Roemer, Bjoern Chapuy, Philippe Armand, Scott J. Rodig, Margaret A. Shipp
Journal: Blood
Blood (2017) 129 (23): 3071–3073.
https://doi.org/10.1182/blood-2017-01-764209
Published: 2017
Journal Articles

In Silico and Functional Characterization of TBL1XR1 as a Tumor Suppressor in Large B-Cell Lymphomas

Bjoern Chapuy, MD PhD, Atanas Kamburov, PhD, Caroline A Coughlin, Chip Stewart, PhD, Andrew Dunford, Miyuki Aono, Jens Loeber, Christopher Sauer, Arthur Su, Margaretha G M Roemer, Scott J Rodig, Gad Getz, PhD, Margaret A. Shipp, MD
Journal: Blood
Blood (2016) 128 (22): 612.
https://doi.org/10.1182/blood.V128.22.612.612
Published: 2016
Journal Articles

Nivolumab (Anti-PD1) Therapy for Relapsed/ Refractory Primary Central Nervous System Lymphoma and Primary Testicular Lymphoma

Lakshmi Nayak, MD, Fabio Iwamoto, MD, Ann S. LaCasce, MD, Srinivasan Mukundan, Jr., Margaretha G M Roemer, Bjoern Chapuy, MD PhD, Philippe Armand, MD PhD, Scott J. Rodig, Margaret A. Shipp, MD
Journal: Blood
Blood (2016) 128 (22): 930.
https://doi.org/10.1182/blood.V128.22.930.930
Published: 2016
Journal Articles

Chromosome 9p24.1/ PD-L1 / PD-L2 Alterations and PD-L1 Expression and Treatment Outcomes in Patients with Classical Hodgkin Lymphoma Treated with Nivolumab (PD-1 Blockade)

Margaretha G M Roemer, Azra H. Ligon, PhD, Andreas Engert, MD, Anas Younes, MD, Armando Santoro, Pier Luigi Zinzani, MD PhD, John M. Timmerman, MD, Stephen Ansell, MD PhD, Philippe Armand, MD PhD, Michelle A Fanale, MD, Voravit Ratanatharathorn, MD, John Kuruvilla, MD, Jonathon B. Cohen, MD, Graham P. Collins, MD PhD, Kerry J Savage, MD, Marek Trneny, Donna S. Neuberg, ScD, Robert A Redd, MS, Benedetto Farsaci, Kazunobu Kato, MD, Anne Sumbul, Scott J Rodig, Margaret A. Shipp, MD
Journal: Blood
Blood (2016) 128 (22): 2923.
https://doi.org/10.1182/blood.V128.22.2923.2923
Published: 2016
Journal Articles

Diffuse large B-cell lymphoma patient-derived xenograft models capture the molecular and biological heterogeneity of the disease

Bjoern Chapuy, Hongwei Cheng, Akira Watahiki, Matthew D. Ducar, Yuxiang Tan, Linfeng Chen, Margaretha G. M. Roemer, Jing Ouyang, Amanda L. Christie, Liye Zhang, Daniel Gusenleitner, Ryan P. Abo, Pedro Farinha, Frederike von Bonin, Aaron R. Thorner, Heather H. Sun, Randy D. Gascoyne, Geraldine S. Pinkus, Paul van Hummelen, Gerald G. Wulf, Jon C. Aster, David M. Weinstock, Stefano Monti, Scott J. Rodig, Yuzhuo Wang, Margaret A. Shipp
Journal: Blood
Blood (2016) 127 (18): 2203–2213.
https://doi.org/10.1182/blood-2015-09-672352
Published: 2016
Includes: Supplemental data
Journal Articles

Targetable genetic features of primary testicular and primary central nervous system lymphomas

Bjoern Chapuy, Margaretha G. M. Roemer, Chip Stewart, Yuxiang Tan, Ryan P. Abo, Liye Zhang, Andrew J. Dunford, David M. Meredith, Aaron R. Thorner, Ekaterina S. Jordanova, Gang Liu, Friedrich Feuerhake, Matthew D. Ducar, Gerald Illerhaus, Daniel Gusenleitner, Erica A. Linden, Heather H. Sun, Heather Homer, Miyuki Aono, Geraldine S. Pinkus, Azra H. Ligon, Keith L. Ligon, Judith A. Ferry, Gordon J. Freeman, Paul van Hummelen, Todd R. Golub, Gad Getz, Scott J. Rodig, Daphne de Jong, Stefano Monti, Margaret A. Shipp
Journal: Blood
Blood (2016) 127 (7): 869–881.
https://doi.org/10.1182/blood-2015-10-673236
Published: 2016
Includes: Supplemental data