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Lorenzo Trippa
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Journal Articles

Results of the promise study from ~30,000 individuals screened for monoclonal gammopathies

Free
Sabine Allam, Sungjae Kim, Jean-Baptiste Alberge, Habib El-Khoury, Floris Chabrun, Jacqueline Perry, Katherine Padgett, Julia Colchie, Joseph Flinn, Grace Fleming, Rachel Choi, Kaitlin Bondi, Ciara Murphy, Sofia Wallin, Luca Bertamini, David Lee, Derek Troske, Dhananjay Sakrikar, David Barnidge, Stephen Harding, David Cordas Dos Santos, Romanos Sklavenitis-Pistofidis, Meletios Dimopoulos, Efstathios Kastritis, Irit Avivi, Wenlong Chen, Maureen Joffe, Elizabeth Karlson, Elizabeth O'Donnell, Omar Nadeem, Lorenzo Trippa, Catherine Marinac, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2025) 146 (Supplement 1): 403.
https://doi.org/10.1182/blood-2025-403
Published: 2025
Journal Articles

Results of the Phase II d-PRISM study: Daratumumab in high-risk MGUS and low-risk smoldering myeloma

Free
Omar Nadeem, Michelle Aranha, Robert Redd, Michael Koontz, Jeffrey Matous, Andrew Yee, Jeffrey Zonder, Andrew Kin, Sophie Magidson, Elizabeth Lightbody, Ting Wu, Floris Chabrun, Jean-Baptiste Alberge, Ankit Dutta, Jacqueline Perry, Ashlee Sturtevant, Mahshid Rahmat, Junko Tsuji, Christine Davie, Caroline Ricciardi, Frances Arters, Marjorie Marto, Amy Goguen, Jacalyn Rosenblatt, Elizabeth O'Donnell, Jacob Laubach, Paul Richardson, Gad Getz, Lorenzo Trippa, Romanos Sklavenitis-Pistofidis, Irene Ghobrial
Journal: Blood
Blood (2025) 146 (Supplement 1): 1533.
https://doi.org/10.1182/blood-2025-1533
Published: 2025
Journal Articles

Serum free light chains in a racially diverse population including African Americans and populations from South Africa

Available to Purchase
Luca Bertamini, Jean-Baptiste Alberge, David J. Lee, Habib El-Khoury, Sungjae Kim, Grace Fleming, Ciara Murphy, Julia Colchie, Maya I. Davis, Jacqueline Perry, Elizabeth D. Lightbody, Sabine Allam, Lindokuhle N. Goqwana, Vinitha Philip, Natalie Smyth, Dhananjay Sakrikar, Mark Perkins, Stephen Harding, Derek Troske, Gad Getz, Elizabeth W. Karlson, Nikhil Munshi, Kenneth C. Anderson, Lorenzo Trippa, Catherine R. Marinac, Wenlong C. Chen, Maureen Joffe, Irene M. Ghobrial
Journal: Blood
Blood (2025) 145 (8): 840–849.
https://doi.org/10.1182/blood.2024026078
Published: 2025
Includes: Supplemental data
Journal Articles

Tumor-Intrinsic and Immune Predictors of Response to Ixazomib, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma

Free
Michelle P. Aranha, Omar Nadeem, Robert A. Redd, Michael Timonian, Sophie Magidson, Elizabeth D. Lightbody, Jean-Baptiste Alberge, Ting Wu, Junko Tsuji, Luca Bertamini, Ankit K. Dutta, Habib El-Khoury, Mark Bustoros, Jacob Laubach, Giada Bianchi, Elizabeth K. O'Donnell, Kenneth C. Anderson, Gad Getz, Lorenzo Trippa, Paul G. Richardson, Romanos Sklavenitis-Pistofidis, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 1928.
https://doi.org/10.1182/blood-2024-203684
Published: 2024
Journal Articles

Early Safety and Efficacy of CAR-T Cell Therapy in Precursor Myeloma: Results of the CAR-PRISM Study Using Ciltacabtagene Autoleucel in High-Risk Smoldering Myeloma

Free
Omar Nadeem, Sarah Nikiforow, Kevin DeBraganca, Anna Bosch-Vilaseca, Elizabeth K. O'Donnell, Adam S. Sperling, Yuxin Liu, Frances Arters, Marjorie Marto, Colin O'Donnell, Brendan Kineavy, Sarah Holmes, Hope Wei, Emily Durlacher, Elizabeth Grimm, Amy Goguen, Rocio Montes de Oca, Lorenzo Trippa, Eric L. Smith, Kenneth C. Anderson, Nikhil C. Munshi, Mark Wildgust, Jerome Ritz, Craig Tendler, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 1027.
https://doi.org/10.1182/blood-2024-202676
Published: 2024
Journal Articles

Improved Risk Stratification of Smoldering Multiple Myeloma (SMM) Using Trajectory Data in the Pangea 2.0 Model: A Multicenter Study in 1,431 Participants

Free
Floris Chabrun, Daniel Schwartz, Susanna Gentile, Tulika R Gupta, Noelia Collado Gisbert, Esperanza Martín-Sánchez, Rosalinda Termini, Jacqueline F Perry, Annie Cowan, Federico Ferrari, Samuel Freeman, Robert A. Redd, Vidhi Patel, Patrick Costello, Catherine Tobia, Romanos Sklavenitis-Pistofidis, Habib El-Khoury, Michael Timonian, David J Lee, Elizabeth D. Lightbody, Hadley Barr, Priya Kaur, Katelyn Downey, Sally Phan, Maya Patel, Jennifer Lamb, Nana Ama Boadi-Acheampong, Foteini Theodorakakou, Despina Fotiou, Christine-Ivy Liacos, Selina J Chavda, Louise Ainley, Elizabeth K. O'Donnell, Catherine R. Marinac, Gad Getz, Omar Nadeem, Kwee Yong, Efstathios Kastritis, Meletios Dimopoulos, Jesús F. San-Miguel, Bruno Paiva, Lorenzo Trippa, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 1017.
https://doi.org/10.1182/blood-2024-205705
Published: 2024
Journal Articles

Phase II Trial of Daratumumab, Bortezomib, Lenalidomide and Dexamethasone in High-Risk Smoldering Multiple Myeloma

Free
Omar Nadeem, Sophie Magidson, Robert A. Redd, Jacob P. Laubach, Clifton C. Mo, Elizabeth K. O'Donnell, Adam S. Sperling, Monique A. Hartley-Brown, Shonali Midha, Yuxin Liu, Frances Arters, Marjorie Marto, Christine Davie, Caroline Ricciardi, Dechen Choden, Ashlee Strutevant, Jillian Alberti, Amy Goguen, Michael Constantine, Pedro Sanz-Altamira, Lorenzo Trippa, Nikhil C. Munshi, Kenneth C. Anderson, Paul G. Richardson, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 3360.
https://doi.org/10.1182/blood-2024-202653
Published: 2024
Journal Articles

Immuno-PRISM: A Randomized Phase II Platform Study of Bispecific Antibodies in High-Risk Smoldering Myeloma

Free
Omar Nadeem, Sophie Magidson, Shonali Midha, Elizabeth K. O'Donnell, Monique A Hartley-Brown, Adam S. Sperling, Robert A. Redd, Marjorie Marto, Christine Davie, Caroline Ricciardi, Dechen Choden, Ashlee Strutevant, Jillian Alberti, Clifton C. Mo, Jacob Laubach, Paul G. Richardson, Kenneth C. Anderson, Nikhil C Munshi, Lorenzo Trippa, Irene M. Ghobrial
Journal: Blood
Blood (2023) 142 (Supplement 1): 206.
https://doi.org/10.1182/blood-2023-177954
Published: 2023
Journal Articles

Phase II Trial of Daratumumab, Bortezomib, Lenalidomide and Dexamethasone in High-Risk Smoldering Multiple Myeloma

Free
Omar Nadeem, Sophie Magidson, Robert A. Redd, Jacob Laubach, Clifton C. Mo, Elizabeth K. O'Donnell, Adam S. Sperling, Monique A Hartley-Brown, Shonali Midha, Marjorie Marto, Christine Davie, Caroline Ricciardi, Dechen Choden, Ashlee Strutevant, Jillian Alberti, Lorenzo Trippa, Nikhil C Munshi, Kenneth C. Anderson, Paul G. Richardson, Irene M. Ghobrial
Journal: Blood
Blood (2023) 142 (Supplement 1): 3382.
https://doi.org/10.1182/blood-2023-177947
Published: 2023
Journal Articles

Clonal Hematopoiesis Is Associated with Increased Risk of Progression of Asymptomatic Waldenström Macroglobulinemia

Free
Sabrin Tahri, Tarek H Mouhieddine, Robert A. Redd, Luisa Maria Lampe, Katarina Nillson, Nang Kham Su, Habib El-Khoury, Amin H Nassar, Elio Adib, Govind Bindra, Sarah Abou Alaiwi, Lorenzo Trippa, David P. Steensma, Jorge J. Castillo, Steven P. Treon, Irene M. Ghobrial, Adam S. Sperling
Journal: Blood
Blood (2021) 138 (Supplement 1): 2678.
https://doi.org/10.1182/blood-2021-149711
Published: 2021
Journal Articles

Genomic Profiling of Smoldering Multiple Myeloma Classifies Molecular Groups with Distinct Pathogenic Phenotypes and Clinical Outcomes

Free
Shankara Anand, Mark Bustoros, Romanos Sklavenitis-Pistofidis, Robert A. Redd, Eileen M Boyle, Yu-Tzu Tai, Carl J Neuse, Selina J Chavda, Cody J. Boehner, Mahshid Rahmat, Benny Zhitomirsky, Andrew Dunford, Ankit K. Dutta, Chip Stewart, Lorenzo Trippa, Tineke Casneuf, Efstathios Kastritis, Brian A Walker, Faith E Davies, Meletios A. Dimopoulos, P. Leif Bergsagel, Kwee Yong, Gareth J. Morgan, François Aguet, Gad Getz, Irene M. Ghobrial
Journal: Blood
Blood (2021) 138 (Supplement 1): 723.
https://doi.org/10.1182/blood-2021-150767
Published: 2021
Journal Articles

Single-Cell RNA-Sequencing Identifies Immune Biomarkers of Response to Immunotherapy in Patients with High-Risk Smoldering Myeloma

Free
Romanos Sklavenitis-Pistofidis, Ankit K. Dutta, Sylvia Ujwary, Robert A. Redd, Alexandra Savell, Léa Fléchon, François Aguet, Nicholas Haradhvala, Oksana Zavidij, Mark Bustoros, Sabrin Tahri, Tarek H Mouhieddine, Nang K. Su, Lily Ardente, Shankara Anand, Jacalyn Rosenblatt, Jeffrey A. Zonder, James J. Vredenburgh, Adam Boruchov, Manisha Bhutani, Saad Z. Usmani, Jeffrey V. Matous, Andrew J. Yee, Andrzej Jakubowiak, Claudia E. Paba-Prada, Julia Prescott, Jacob P. Laubach, Salomon Manier, Omar Nadeem, Paul G. Richardson, Ashraf Z. Badros, Lorenzo Trippa, Maria-Victoria Mateos, Gad Getz, Irene M. Ghobrial
Journal: Blood
Blood (2021) 138 (Supplement 1): 330.
https://doi.org/10.1182/blood-2021-147623
Published: 2021
Journal Articles

A Phase II Study of Daratumumab in Patients with High-Risk MGUS and Low-Risk Smoldering Multiple Myeloma: First Report of Efficacy and Safety

Free
Omar Nadeem, MD, Robert Redd, Laura V. Stampleman, Jeffrey V. Matous, MD, Andrew J. Yee, MD, Jeffrey A. Zonder, Andrew Kin, MD, Jacalyn Rosenblatt, MD, Mark Bustoros, MD, Julia Prescott, MSN,NP, Alexandra Savell, BS, Kathleen Guimond, RN, Erin Frey, RN, Rachel Styles, BS, Adrienne Bielawski, Cody J Boehner, BS, Nang Kham Su, BA, Multiple Myeloma Research Foundation Multiple Myeloma Research Foundation, The Leukemia & Lymphoma Society The Leukemia & Lymphoma Society, BCRP Blood Cancer Research Partnership, Adam S Sperling, MD PhD, Giada Bianchi, MD, Jacob P. Laubach, MD, Jorge J. Castillo, MD, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD, Paul G. Richardson, MD, Lorenzo Trippa, Irene M. Ghobrial, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1898.
https://doi.org/10.1182/blood-2019-129103
Published: 2019
Journal Articles

Bortezomib overcomes the negative impact of CXCR4 mutations on survival of Waldenstrom macroglobulinemia patients

Free
Romanos Sklavenitis-Pistofidis, Marzia Capelletti, Chia-Jen Liu, Mairead Reidy, Oksana Zavidij, Daisy Huynh, Patrick Henrick, Alexandra Savell, Kaitlen Reyes, Bradley Rivotto, Mark Bustoros, Adriana Perilla-Glen, Lorenzo Trippa, Jorge J. Castillo, Steven P. Treon, Irene M. Ghobrial
Journal: Blood
Blood (2018) 132 (24): 2608–2612.
https://doi.org/10.1182/blood-2018-07-863241
Published: 2018
Journal Articles

Final Results of a Phase 2 Study of Modified Lenalidomide, Bortezomib, and Dexamethasone (RVD lite) in Transplant-Ineligible Multiple Myeloma

Free
Elizabeth O'Donnell, MD, Jacob Laubach, MD, Andrew J Yee, MD, Tianqi Chen, Carol Ann Huff, MD, Frank G. Basile, MD, Philip Wade, MD, Claudia Paba-Prada, MD, Irene M. Ghobrial, MD, Robert Schlossman, MD, Jill Burke, Harrington Cynthia, Kathleen Lively, Hannah Lyons, Nikhil Munshi, MD, Lorenzo Trippa, PhD, Kenneth C Anderson, MD, Paul G Richardson, MD, Noopur Raje, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3126.
https://doi.org/10.1182/blood.V130.Suppl_1.3126.3126
Published: 2017
Journal Articles

Prognostic role of circulating exosomal miRNAs in multiple myeloma

Free
Salomon Manier, Chia-Jen Liu, Hervé Avet-Loiseau, Jihye Park, Jiantao Shi, Federico Campigotto, Karma Z. Salem, Daisy Huynh, Siobhan V. Glavey, Bradley Rivotto, Antonio Sacco, Aldo M. Roccaro, Juliette Bouyssou, Stéphane Minvielle, Philippe Moreau, Thierry Facon, Xavier Leleu, Edie Weller, Lorenzo Trippa, Irene M. Ghobrial
Journal: Blood
Blood (2017) 129 (17): 2429–2436.
https://doi.org/10.1182/blood-2016-09-742296
Published: 2017
Includes: Supplemental data