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Tarek H Mouhieddine
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Journal Articles

Multimodal Single-Cell Transcriptomic and Proteomic Correlatives of Patients Outcomes Following Anti-BCMA Cellular Therapy with Ciltacabtagene Autoleucel (Cilta-cel) in Relapsed Multiple Myeloma

Junia Vieira dos Santos, David Melnekoff, Adolfo Aleman, Sherry Bhalla, Tarek H. Mouhieddine, Oliver Van Oekelen, Sridevi Rajeeve, Bhaskar Upadhyaya, Yogita Ghodke-Puranik, Violetta Leshchenko, Adeeb Rahman, Shaked Afik, Hadas Lewinsky, Santiago Thibaud, Hearn Jay Cho, Joshua Richter, Cesar Rodriguez, Larysa Sanchez, Adriana C Rossi, Shambavi Richard, Ajai Chari, Sundar Jagannath, Samir Parekh, Alessandro Lagana
Journal: Blood
Blood (2023) 142 (Supplement 1): 93.
https://doi.org/10.1182/blood-2023-186395
Published: 2023
Journal Articles

Immune Dynamics Associated with Patient Outcomes Identified By Multimodal Single-Cell Analysis in Multiple Myeloma Patients Receiving Talquetamab Monotherapy

Tarek H. Mouhieddine, Junia Vieira dos Santos, Yogita Ghodke-Puranik, Adolfo Aleman, David Melnekoff, Bhaskar Upadhyaya, Adeeb Rahman, Shaked Afik, Hadas Lewinsky, Santiago Thibaud, Adriana C Rossi, Shambavi Richard, Cesar Rodriguez, Joshua Richter, Hearn Jay Cho, Larysa Sanchez, Sundar Jagannath, Ajai Chari, Alessandro Lagana, Samir Parekh
Journal: Blood
Blood (2023) 142 (Supplement 1): 1927.
https://doi.org/10.1182/blood-2023-185308
Published: 2023
Journal Articles

Clinical Outcomes of Subsequent Therapies in Patients with Relapsed/Refractory Multiple Myeloma Following Talquetamab Treatment: Analyses from the Phase 1/2 MonumenTAL-1 Study

Larysa Sanchez, Carolina Schinke, Amrita Krishnan, Jésus G Berdeja, Niels WCJ van de Donk, María Victoria Mateos, Ajai Chari, Samir Parekh, Tarek H. Mouhieddine, Sundar Jagannath, Nizar J Bahlis, Cyrille Touzeau, Albert Oriol, Jesus San-Miguel, Paula Rodriguez Otero, Monique C Minnema, Michela Campagna, Tara J Masterson, Brandi W Hilder, Jaszianne Tolbert, Thomas Renaud, Kathleen Gray, Damiette Smit, Christoph Heuck, Leo Rasche
Journal: Blood
Blood (2023) 142 (Supplement 1): 2007.
https://doi.org/10.1182/blood-2023-182330
Published: 2023
Journal Articles

Outcomes after CAR T Cells in Multiple Myeloma Patients with Extramedullary and Paramedullary Disease

Darren Pan, Tarek H. Mouhieddine, Weijia Fu, Erin Moshier, Samir Parekh, Sundar Jagannath, Adriana C Rossi, Joshua Richter, Cesar Rodriguez, Larysa J Sanchez, Santiago Thibaud, Hearn Jay Cho, Shambavi Richard
Journal: Blood
Blood (2023) 142 (Supplement 1): 1006.
https://doi.org/10.1182/blood-2023-177749
Published: 2023
Journal Articles

Inflammatory Biomarkers and Outcomes in Multiple Myeloma Patients after CAR T-Cell Therapy

Darren Denjay Pan, Tarek H. Mouhieddine, Weijia Fu, Erin Moshier, Samir Parekh, Sundar Jagannath, Adriana C Rossi, Hearn Jay Cho, Joshua Richter, Larysa J Sanchez, Santiago Thibaud, Cesar Rodriguez, Shambavi Richard
Journal: Blood
Blood (2023) 142 (Supplement 1): 92.
https://doi.org/10.1182/blood-2023-188310
Published: 2023
Journal Articles

Timing of Vaccination Impacts Serological Response to COVID-19 Myeloma Patients after BCMA-Targeted CAR T

Oliver Van Oekelen, Morgan Van Kesteren, Adolfo Aleman, Ariel Kogan Zajdman, Lucia Y Chen, Tarek H. Mouhieddine, Bhaskar Upadhyaya, Kseniya Serebryakova, Katerina Kappes, Sarita Agte, Annika Oostenink, Hayley Jackson, Charles Gleason, Komal Srivastava, Santiago Thibaud, Larysa Sanchez, Cesar Rodriguez, Joshua Richter, Hearn Jay Cho, Adriana C Rossi, Shambavi Richard, Carlos Cordon-Cardo, Ania Wajnberg, Florian Krammer, Sundar Jagannath, Viviana Simon, Samir Parekh
Journal: Blood
Blood (2023) 142 (Supplement 1): 3350.
https://doi.org/10.1182/blood-2023-184409
Published: 2023
Journal Articles

Demographic Disparities in Clinical Trial Enrollment of US Patients with Newly-Diagnosed Multiple Myeloma

Bruno Almeida Costa, Neha Debnath, Thomaz Alexandre Costa, Raphael Bertasi, Tarek H. Mouhieddine, Karthik Nath, Adriana C Rossi
Journal: Blood
Blood (2023) 142 (Supplement 1): 7371.
https://doi.org/10.1182/blood-2023-190861
Published: 2023
Journal Articles

Interventions and outcomes of patients with multiple myeloma receiving salvage therapy after BCMA-directed CAR T therapy

Clinical Trials & Observations
Oliver Van Oekelen, Karthik Nath, Tarek H. Mouhieddine, Tasmin Farzana, Adolfo Aleman, David T. Melnekoff, Yogita Ghodke-Puranik, Gunjan L. Shah, Alexander Lesokhin, Sergio Giralt, Santiago Thibaud, Adriana Rossi, Cesar Rodriguez, Larysa Sanchez, Joshua Richter, Shambavi Richard, Hearn J. Cho, Ajai Chari, Saad Z. Usmani, Sundar Jagannath, Urvi A. Shah, Sham Mailankody, Samir Parekh
Journal: Blood
Blood (2023) 141 (7): 756–765.
https://doi.org/10.1182/blood.2022017848
Published: 2023
Includes: Supplemental data
Journal Articles

Single-Cell RNA-Sequencing Identifies Immune Biomarkers of Progression in Patients with High-Risk Smoldering Multiple Myeloma Treated with Immunotherapy

Romanos Sklavenitis-Pistofidis, Michelle P. Aranha, Nicholas J. Haradhvala, Shohreh Varmeh, Daniel Heilpern-Mallory, Ting Wu, Nang Kham Su, Elizabeth D. Lightbody, François Aguet, Oksana Zavidij, Sabrin Tahri, Tarek H. Mouhieddine, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2022) 140 (Supplement 1): 268–269.
https://doi.org/10.1182/blood-2022-168839
Published: 2022
Journal Articles

Salvage with Sequential T Cell Redirection for Myeloma Patients Who Have Previously Progressed on T Cell Directed Therapy Is Associated with Significant Cellular Activation of the Immune Microenvironment

Adolfo Aleman, Ariel Kogan Zajdman, Yogita Ghodke-Puranik, Bhaskar Upadhyaya, Tarek H. Mouhieddine, Oliver Van Oekelen, Larysa Sanchez, Shambavi Richard, Adriana Rossi, Joshua Richter, Hearn J. Cho, Cesar Rodriguez, Ajai Chari, Sundar Jagannath, Samir Parekh
Journal: Blood
Blood (2022) 140 (Supplement 1): 4193–4195.
https://doi.org/10.1182/blood-2022-169538
Published: 2022
Journal Articles

Monitoring Plasma Cells and Clonal Emergence through Genome Sequencing of Circulating Tumor Cells for Minimally Invasive Molecular Characterization of Multiple Myeloma

Ankit K. Dutta, Jean-Baptiste Alberge, Elizabeth D. Lightbody, Cody J. Boehner, Romanos Sklavenitis-Pistofidis, Amanda Cao, Tarek H. Mouhieddine, Anna Cowan, Nang Kham Su, Andrew Dunford, Erica Horowitz, Hadley Barr, Jenna B. Beckwith, Laura Hevenor, Jacqueline Perry, Ornkleaw Zepp, Thai Bui, Steven Gross, Omar Nadeem, Chip Stewart, Daniel Auclair, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2022) 140 (Supplement 1): 9927–9928.
https://doi.org/10.1182/blood-2022-169034
Published: 2022
Journal Articles

Outcomes with Panobinostat in Heavily Pretreated Multiple Myeloma Patients

Darren Pan, Tarek H. Mouhieddine, Ranjan Upadhyay, Nicole Casasanta, Angela Lee, Nicole Zubizarreta, Erin Moshier, Joshua Richter
Journal: Blood
Blood (2022) 140 (Supplement 1): 12483–12484.
https://doi.org/10.1182/blood-2022-159806
Published: 2022
Journal Articles

Monogenic and Polygenic Contributions to Venous Thromboembolism (VTE) and Splanchnic Thrombosis in Patients (pts) with Pancreatic Cancer (PC)

Amin H Nassar, Stefan Groha, Edward El-am, Antoine Bejjani, Talal El Zarif, Tarek H. Mouhieddine, Sarah Abou Alaiwi, Elio Adib, Kimmie Ng, Jean M. M Connors, Alfred I Lee, Alexander Gusev
Journal: Blood
Blood (2022) 140 (Supplement 1): 5525–5526.
https://doi.org/10.1182/blood-2022-163804
Published: 2022
Journal Articles

Comprehensive Characterization of Prolonged Unexplained Cytopenias in Relapsed/Refractory Multiple Myeloma Patients Following BCMA-Directed CAR-T Cell Therapy

Santiago Thibaud, Md. Babu Mia, Oliver Van Oekelen, Tarek H. Mouhieddine, Christoph Schaniel, Yogita Ghodke-Puranik, Adolfo Aleman, Bhaskar Upadhyaya, Guido Lancman, Alessandro Lagana, Shambavi Richard, Adriana Rossi, Ajai Chari, Larysa Sanchez, Cesar Rodriguez, Hearn J. Cho, Joshua Richter, Ronald Hoffman, Sundar Jagannath, Samir Parekh
Journal: Blood
Blood (2022) 140 (Supplement 1): 614–616.
https://doi.org/10.1182/blood-2022-165646
Published: 2022
Journal Articles

Non-Invasive Liquid Biopsy to Quantify and Molecularly Characterize Circulating Multiple Myeloma Cells in the Assessment of Precursor Disease Pathology

Ankit K. Dutta, Elizabeth D. Lightbody, Ziao Lin, Jean-Baptiste Alberge, Romanos Sklavenitis-Pistofidis, Tarek H Mouhieddine, Annie Cowan, Nang K. Su, Cody J. Boehner, Hadley Barr, Steven Gross, Ornkleaw Zepp, Thai Bui, Jared Mayes, Daniel Auclair, Gad Getz, Irene M. Ghobrial
Journal: Blood
Blood (2021) 138 (Supplement 1): 78.
https://doi.org/10.1182/blood-2021-150622
Published: 2021
Journal Articles

Clonal Hematopoiesis Is Associated with Increased Risk of Progression of Asymptomatic Waldenström Macroglobulinemia

Sabrin Tahri, Tarek H Mouhieddine, Robert A. Redd, Luisa Maria Lampe, Katarina Nillson, Nang Kham Su, Habib El-Khoury, Amin H Nassar, Elio Adib, Govind Bindra, Sarah Abou Alaiwi, Lorenzo Trippa, David P. Steensma, Jorge J. Castillo, Steven P. Treon, Irene M. Ghobrial, Adam S. Sperling
Journal: Blood
Blood (2021) 138 (Supplement 1): 2678.
https://doi.org/10.1182/blood-2021-149711
Published: 2021
Journal Articles

Clinical Outcomes and Treatment Strategies for Relapsed/Refractory Myeloma Patients after Relapse on BCMA-Targeted CAR T

Oliver Van Oekelen, Tarek H. Mouhieddine, Darren Pan, Megan Metzger, Sarita Agte, Adolfo Aleman, David T. Melnekoff, Guido Lancman, Alessandro Lagana, Shambavi Richard, Larysa Sanchez, Joshua Richter, Hearn Jay Cho, Ajai Chari, Sundar Jagannath, Samir Parekh
Journal: Blood
Blood (2021) 138 (Supplement 1): 2704.
https://doi.org/10.1182/blood-2021-152243
Published: 2021
Journal Articles

Single Cell Characterization of Myeloma and Its Precursor Conditions Reveals Transcriptional Signatures of Early Tumorigenesis

Rebecca Boiarsky, Nicholas Haradhvala, Romanos Sklavenitis-Pistofidis, Tarek H Mouhieddine, Jean-Baptiste Alberge, Oksana Zavidij, Danielle Firer, Shankara Anand, Habib El-Khoury, François Aguet, David Sontag, Irene M. Ghobrial, Gad Getz
Journal: Blood
Blood (2021) 138 (Supplement 1): 2219.
https://doi.org/10.1182/blood-2021-150889
Published: 2021
Journal Articles

Clinical Outcomes of Relapsed/Refractory Multiple Myeloma Patients Following Treatment with Bispecific Antibodies (BiAbs)

Tarek H. Mouhieddine, Oliver Van Oekelen, Darren Pan, Sarita Agte, Adolfo Aleman, David T. Melnekoff, Guido Lancman, Santiago Thibaud, Larysa Sanchez, Shambavi Richard, Joshua Richter, Hearn Jay Cho, Ajai Chari, Sundar Jagannath, Samir Parekh
Journal: Blood
Blood (2021) 138 (Supplement 1): 821.
https://doi.org/10.1182/blood-2021-151585
Published: 2021
Journal Articles

Suboptimal Humoral and Cellular Immune Response to SARS-CoV-2 RNA Vaccination in Myeloma Patients Is Associated with Anti-CD38 and BCMA-Targeted Treatment

Oliver Van Oekelen, Sarita Agte, Adolfo Aleman, Bhaskar Upadhyaya, Charles R. Gleason, Komal Srivastava, Katherine F. Beach, Kevin Tuballes, Katerina Kappes, Tarek H. Mouhieddine, Bo Wang, Seunghee Kim-Schulze, Ajai Chari, Sacha Gnjatic, Nina Bhardwaj, Brian D. Brown, Miriam Merad, Carlos Cordon-Cardo, Florian Krammer, Sundar Jagannath, Viviana Simon, Ania Wajnberg, Samir Parekh
Journal: Blood
Blood (2021) 138 (Supplement 1): 822.
https://doi.org/10.1182/blood-2021-152365
Published: 2021