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Rudy Birsen
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Journal Articles

Real-World Outcomes Using Front-Line Midostaurine in Combination with Intensive Chemotherapy for Patients Aged ≥ 60 Years Old with FLT3 Mutated Acute Myeloid Leukemia

Gaspar Aspas Requena, Pierre Yves Dumas, Rebeca Rodriguez Veiga, Sarah Bertoli, Cristina Gil, Celestine Simand, Fernando Jesús Ramos-Ortega, Pierre Peterlin, Josefina Serrano, Rudy Birsen, Teresa Bernal Del Castillo, Emmanuelle Tavernier, Mar Tormo, Martin Carre, Maria Jose Garcia, Adrien Contejean, Rosalia Riaza Grau, Corentin Orvain, Jose Antonio Pérez-Simón, Esther Perez Santaolla, Lauren Veronese, Beatriz De Rueda Ciller, Eric Delabesse, Antonio Gutiérrez, Ariane Mineur, Adolfo De La Fuente Burguera, Romain Guieze, Arnaud Pigneux, Pau Montesinos, Christian Recher, David Matínez-Cuadrón
Journal: Blood
Blood (2023) 142 (Supplement 1): 2864.
https://doi.org/10.1182/blood-2023-190128
Published: 2023
Journal Articles

Rare germline complement factor H variants in patients with paroxysmal nocturnal hemoglobinuria

Clinical Trials & Observations Brief Report
Pedro Henrique Prata, Jacques-Emmanuel Galimard, Flore Sicre de Fontbrune, Anna Duval, Paula Vieira Martins, Stephane Roncelin, Pierre-Édouard Debureaux, Anne-Claire Lepretre, Lise Larcher, Rudy Birsen, Ygal Benhamou, Jean Soulier, Gérard Socié, Véronique Fremeaux-Bacchi, Régis Peffault de Latour
Journal: Blood
Blood (2023) 141 (15): 1812–1816.
https://doi.org/10.1182/blood.2022017019
Published: 2023
Includes: Supplemental data
Journal Articles

Prognostic value and oncogenic landscape of TP53 alterations in adult and pediatric T-ALL

Clinical Trials & Observations
Mathieu Simonin, Guillaume P. Andrieu, Rudy Birsen, Marie Balsat, Guillaume Hypolite, Lucien Courtois, Carlos Graux, Nathalie Grardel, Jean-Michel Cayuela, Françoise Huguet, Yves Chalandon, Yannick Le Bris, Elizabeth Macintyre, Virginie Gandemer, Arnaud Petit, Philippe Rousselot, André Baruchel, Didier Bouscary, Olivier Hermine, Nicolas Boissel, Vahid Asnafi
Journal: Blood
Blood (2023) 141 (11): 1353–1358.
https://doi.org/10.1182/blood.2022017755
Published: 2023
Includes: Supplemental data
Journal Articles

C/EBPα Confers Dependence to Fatty Acid Biosynthetic Pathways and Vulnerability to Lipid Oxidative Stress in FLT3-Mutant Leukemia

Marie Sabatier, Rudy Birsen, Laura Lauture, Léa Goupille, Clement Larrue, Sarah Mouche, Christian Recher, Jerome Tamburini, Jean-Emmanuel Sarry
Journal: Blood
Blood (2022) 140 (Supplement 1): 3084–3085.
https://doi.org/10.1182/blood-2022-159656
Published: 2022
Journal Articles

Combination of the MEK Inhibitor Trametinib and Pyrvinium Pamoate Efficiently Targets RAS Pathway-Mutated Acute Myeloid Leukemia in Preclinical Models

Justine Decroocq, MD, Rudy Birsen, MD, Jordi Mano, MSc, Guillemette Fouquet, Mathilde Gotanègre, MSc, Laury Poulain, PhD, Sarah Mouche, Anne-Sophie Alary, Adrien Grenier, MD PhD, Fetta Mazed, PhD, Johanna Mondesir, MD, Nicolas Chapuis, PharmD, PhD, Aicha Boughalem, MD, Marc Le Lorc'h, Ivan C Moura, PhD, Olivier Hermine, MD PhD, Isabelle Radford-Weiss, Jean-Emmanuel Sarry, PhD, Eric Pasmant, MD PhD, Olivier Kosmider, PharmD, PhD, Didier Bouscary, MD PhD, Jerome Tamburini, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2671.
https://doi.org/10.1182/blood-2019-123418
Published: 2019
Journal Articles

PKR-like Endoplasmic Reticulum Kinase Mediates Apoptosis Induced By Pharmacological AMP-Activated Protein Kinase Activation in Acute Myeloid Leukemia

Laury Poulain, PhD, Adrien Grenier, MD PhD, Johanna Mondesir, MD, Arnaud Jacquel, PhD, Claudie Bosc, Lucille Stuani, PhD, Rudy Birsen, MD, Sarah Mouche, Justine Decroocq, MD, Fetta Mazed, PhD, Benoit Viollet, PhD, Patrick Auberger, PhD, Pierre Sujobert, MD PhD, Didier Bouscary, MD PhD, Jean-Emmanuel Sarry, PhD, Jerome Tamburini, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2552.
https://doi.org/10.1182/blood-2019-123364
Published: 2019
Journal Articles

Evaluation of Novel Endpoints As Treatment Outcome in Allogeneic Hematopoietic Stem Cell Transplantation: A Comparison of "Classical" and "Refined" Definition of Graft-Versus Host Disease Free and Relapse Free Survival for Registry-Based Studies

Simona Pagliuca, Antonio M Risitano, MD PhD, Flore Sicre De Fontbrune, MD, David Michonneau, MD PhD, Alban Villate, MD, Rudy Birsen, Camille Rouzaud, Aurelien Sutra del Galy, Nabergoj Mitja, MD, Regis Peffault De Latour, MD PhD, Marie Robin, MD PhD, Gérard Socié, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3311.
https://doi.org/10.1182/blood.V130.Suppl_1.3311.3311
Published: 2017
Journal Articles

Outcomes of Hematopoietic Stem Cell Transplantation after Chronic Graft Versus Host Disease and Evaluation of Revised Failure Free Survival in a Retrospective Analysis from Two Referral Centers.

Simona Pagliuca, Flore Sicre De Fontbrune, MD, Antonio M Risitano, MD PhD, David Michonneau, MD PhD, Alban Villate, MD, Rudy Birsen, Camille Rouzaud, Aurelien Sutra del Galy, Nabergoj Mitja, MD, Regis Peffault De Latour, MD PhD, Gérard Socié, MDPhD, Marie Robin, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4578.
https://doi.org/10.1182/blood.V130.Suppl_1.4578.4578
Published: 2017
Journal Articles

Efficacy and Safety of Intensive Etoposide Aracytine Consolidation Following Rituximab Methotrexate Temozolomide Induction in Newly Diagnosed Primary Central Nervous System Lymphoma

Rudy Birsen, Estelle Blanc, MD, Barbara Burroni, MD, Chloe Broudin, MD, Lise Willems, MD, Marielle Legoff, MD, Emmanuelle Leray, MD, Sylvain Pilorge, MD, Sawsen Salah, MD, Aude Quentin, MD, Bénédicte Deau-Fisher, MD, Patricia Franchi, MD, Marguerite Vignon, MD, Laurence Mabille, MD, Charles Nguyen, MD, Youlia Kirova, MD, Pascale Varlet, MD, Arnault tauziede-Espariat, MD, Myriam Edjlali, MD, Dezamis Edouard, MD, Carole Soussain, MD PhD, Caroline Houillier, MD, Johan Pallud, MDPhD, Diane Damotte, MDPhD, Didier Bouscary, MDPhD, Jerome Tamburini Bonnefoy, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1573.
https://doi.org/10.1182/blood.V130.Suppl_1.1573.1573
Published: 2017
Journal Articles

Prognostic Value of Early 18F-FDG PET/CT Scanner Evaluation in Immunocompetent Primary CNS Lymphoma Patients

Rudy Birsen, Estelle Blanc, MD, Barbara Burroni, MD, Chloe Broudin, MD, Lise Willems, MD, Marielle Legoff, MD, Emmanuelle Leray, MD, Sylvain Pilorge, MD, Sawsen Salah, MD, Aude Quentin, MD, Bénédicte Deau-Fisher, MD, Patricia Franchi, MD, Marguerite Vignon, MD, Laurence Mabille, MD, Charles Nguyen, MD, Youlia Kirova, MD, Pascale Varlet, MD, Arnault tauziede-Espariat, MD, Myriam Edjlali, MD, Dezamis Edouard, MD, Khe Hoang-xuan, MD PhD, Caroline Houillier, MD, Carole Soussain, MD PhD, Johan Pallud, MDPhD, Diane Damotte, MDPhD, Didier Bouscary, MDPhD, Jerome Tamburini Bonnefoy, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4169.
https://doi.org/10.1182/blood.V130.Suppl_1.4169.4169
Published: 2017
Journal Articles

Ibrutinib responsive central nervous system involvement in chronic lymphocytic leukemia

Clinical Trials & Observations
Anne Wanquet, Rudy Birsen, Richard Lemal, Mathilde Hunault, Véronique Leblond, Thérèse Aurran-Schleinitz
Journal: Blood
Blood (2016) 127 (19): 2356–2358.
https://doi.org/10.1182/blood-2016-02-697193
Published: 2016
Journal Articles

Central Nervous System Involvement in Chronic Lymphocytic Leukemia: Diagnosis and Treatment in a Retrospective Cohort of Thirty Patients

Anne Wanquet, Rudy Birsen, Sylvain Choquet, MD, Vincent Levy, MD PhD, Jehan Dupuis, MD, Stephane Lepretre, MD, Daniel Re, MD, Jonathan Fahri, Mathilde Hunault, MD PhD, Charlotte Bonnet, Anne-Sophie Michallet, MD, Loic Ysebaert, MD PhD, Richard Lemal, MD, Thierry Lamy, MD PhD, Richard Delarue, MD, Atchroue Johnson Ansah, Sylvain P Chantepie, MD, Xavier Troussard, MD PhD, Frederic Davi, Florence Cymbalista, MD PhD, Pierre-Yves Dietrich, Veronique Leblond, MD PhD, Therese Aurran-Schleinitz, MD
Journal: Blood
Blood (2015) 126 (23): 2948.
https://doi.org/10.1182/blood.V126.23.2948.2948
Published: 2015
Journal Articles

Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition

Nathalie Jacque, Anne Marie Ronchetti, Clément Larrue, Godelieve Meunier, Rudy Birsen, Lise Willems, Estelle Saland, Justine Decroocq, Thiago Trovati Maciel, Mireille Lambert, Laury Poulain, Marie Anne Hospital, Pierre Sujobert, Laure Joseph, Nicolas Chapuis, Catherine Lacombe, Ivan Cruz Moura, Susan Demo, Jean Emmanuel Sarry, Christian Recher, Patrick Mayeux, Jérôme Tamburini, Didier Bouscary
Journal: Blood
Blood (2015) 126 (11): 1346–1356.
https://doi.org/10.1182/blood-2015-01-621870
Published: 2015
Includes: Supplemental data