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Thiago Trovati Maciel
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Journal Articles

New Insights into Cellular Defects during Haematopoiesis of Sickle Cell Disease Using the Townes Mouse Model

Julien Grenier, Barbara Peyrard, Auria Godard, Julien Cheyrol, Thiago Trovati Maciel, Wassim El Nemer, Maria De Grandis
Journal: Blood
Blood (2023) 142 (Supplement 1): 3855.
https://doi.org/10.1182/blood-2023-181742
Published: 2023
Journal Articles

Sputum IL-6 Level Is a Potential Predictor and Severity Marker of Acute Chest Syndrome in Sickle Cell Disease

Slimane Allali, Juliette Elie, Mariane de Montalembert, Melissa Taylor, Joséphine Brice, Stéphanie Chhun, Rachel Rignault-Bricard, Claire Heilbronner, Thiago Trovati Maciel, Olivier Hermine
Journal: Blood
Blood (2022) 140 (Supplement 1): 8265.
https://doi.org/10.1182/blood-2022-166823
Published: 2022
Journal Articles

HbS promotes TLR4-mediated monocyte activation and proinflammatory cytokine production in sickle cell disease

Slimane Allali, Rachel Rignault-Bricard, Mariane de Montalembert, Melissa Taylor, Tahar Bouceba, Olivier Hermine, Thiago Trovati Maciel
Journal: Blood
Blood (2022) 140 (18): 1972–1982.
https://doi.org/10.1182/blood.2021014894
Published: 2022
Includes: Supplemental data
Journal Articles

IMR-261, a Novel Oral Nrf2 Activator, Induces Fetal Hemoglobin in Human Erythroblasts, Reduces VOCs, and Ameliorates Ineffective Erythropoiesis in Experimental Mouse Models of Sickle Cell Disease and Beta-Thalassemia

Thiago Trovati Maciel, Caroline Carvalho, Rachel Rignault, Biree Andemariam, Betty S. Pace, Jennifer Isler OCain, Rahul Ballal
Journal: Blood
Blood (2021) 138 (Supplement 1): 853.
https://doi.org/10.1182/blood-2021-149528
Published: 2021
Journal Articles

PDE9 Inhibition By IMR-687 Improves Markers of Beta-Thalassemia in the Hbb th1/th1 Experimental Mouse Model

Thiago Trovati Maciel, Caroline Carvalho, Rachel Rignault, Slimane Allali, Biree Andemariam, Jennifer Isler OCain, Rahul Ballal
Journal: Blood
Blood (2021) 138 (Supplement 1): 945.
https://doi.org/10.1182/blood-2021-149481
Published: 2021
Journal Articles

Immune Profile of Sickle Cell Anemia Patients Treated with Allogeneic Stem Cell Transplantation

Julia Teixeira Cottas De Azevedo, MSc, Nathalia Ziegler de Oliveira, Keli Cristina de Lima, BSc, Thalita Cristina de Mello Costa, MD, Patrícia Vianna Bonini Palma, BSc, Dimas Tadeu Covas, MD PhD, Eduardo Donadi, Thiago Trovati Maciel, PhD, Olivier Hermine, MD PhD, Belinda Pinto Simões, MD PhD, Kelen Cristina Ribeiro Malmegrim, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5483.
https://doi.org/10.1182/blood.V130.Suppl_1.5483.5483
Published: 2017
Journal Articles

Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition

Nathalie Jacque, Anne Marie Ronchetti, Clément Larrue, Godelieve Meunier, Rudy Birsen, Lise Willems, Estelle Saland, Justine Decroocq, Thiago Trovati Maciel, Mireille Lambert, Laury Poulain, Marie Anne Hospital, Pierre Sujobert, Laure Joseph, Nicolas Chapuis, Catherine Lacombe, Ivan Cruz Moura, Susan Demo, Jean Emmanuel Sarry, Christian Recher, Patrick Mayeux, Jérôme Tamburini, Didier Bouscary
Journal: Blood
Blood (2015) 126 (11): 1346–1356.
https://doi.org/10.1182/blood-2015-01-621870
Published: 2015
Includes: Supplemental data
Journal Articles

Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia

Lise Willems, Nathalie Jacque, Arnaud Jacquel, Nathalie Neveux, Thiago Trovati Maciel, Mireille Lambert, Alain Schmitt, Laury Poulain, Alexa S. Green, Madalina Uzunov, Olivier Kosmider, Isabelle Radford-Weiss, Ivan Cruz Moura, Patrick Auberger, Norbert Ifrah, Valérie Bardet, Nicolas Chapuis, Catherine Lacombe, Patrick Mayeux, Jérôme Tamburini, Didier Bouscary
Journal: Blood
Blood (2013) 122 (20): 3521–3532.
https://doi.org/10.1182/blood-2013-03-493163
Published: 2013
Includes: Supplemental data
Journal Articles

The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation

Alexa S. Green, Nicolas Chapuis, Thiago Trovati Maciel, Lise Willems, Mireille Lambert, Christophe Arnoult, Olivier Boyer, Valerie Bardet, Sophie Park, Marc Foretz, Benoit Viollet, Norbert Ifrah, François Dreyfus, Olivier Hermine, Ivan Cruz Moura, Catherine Lacombe, Patrick Mayeux, Didier Bouscary, Jerome Tamburini
Journal: Blood
Blood (2010) 116 (20): 4262–4273.
https://doi.org/10.1182/blood-2010-02-269837
Published: 2010
Includes: Supplemental data