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Ivan Cruz Moura
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Journal Articles

HFE Gene Mutation Status Predicts Response to Gemtuzumab Ozogamicin in AML

Etienne Paubelle, Alice Marceau, Florence Zylbersztejn, Mickael Dussiot, Ivan Cruz Moura, PhD, Pascale Cornillet-Lefebvre, MD, Jacques Delaunay, MD, Alan K. Burnett, Sylvie Castaigne, Philippe Guardiola, MD, Norbert Ifrah, MD PhD, Hervé Dombret, Claude Preudhomme, Robert K Hills, DPhil, Olivier Hermine
Journal: Blood
Blood (2015) 126 (23): 1307.
https://doi.org/10.1182/blood.V126.23.1307.1307
Published: 2015
Journal Articles

Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition

Nathalie Jacque, Anne Marie Ronchetti, Clément Larrue, Godelieve Meunier, Rudy Birsen, Lise Willems, Estelle Saland, Justine Decroocq, Thiago Trovati Maciel, Mireille Lambert, Laury Poulain, Marie Anne Hospital, Pierre Sujobert, Laure Joseph, Nicolas Chapuis, Catherine Lacombe, Ivan Cruz Moura, Susan Demo, Jean Emmanuel Sarry, Christian Recher, Patrick Mayeux, Jérôme Tamburini, Didier Bouscary
Journal: Blood
Blood (2015) 126 (11): 1346–1356.
https://doi.org/10.1182/blood-2015-01-621870
Published: 2015
Includes: Supplemental data
Journal Articles

Exogenous Apo-Transferrin Increases Monoferric Transferrin, Decreasing Cytosolic Iron Uptake and Heme and Globin Synthesis in β-Thalassemic Mice

Tenzin Choesang, Huihui Li, MS, Michael Dussiot, Thiago Maciel, PhD, Laura Breda, PhD, Daniel Garcia Santos, PhD, Huiyong Chen, PhD, Maria Feola, Weili Bao, Petra Pham, Antonia Follenzi, Guiyuan Li, Ivan Cruz Moura, PhD, Prem Ponka, MD PhD, Robert E Fleming, MD, Stefano Rivella, PhD, Yelena Ginzburg, MD
Journal: Blood
Blood (2014) 124 (21): 4037.
https://doi.org/10.1182/blood.V124.21.4037.4037
Published: 2014
Journal Articles

Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia

Lise Willems, Nathalie Jacque, Arnaud Jacquel, Nathalie Neveux, Thiago Trovati Maciel, Mireille Lambert, Alain Schmitt, Laury Poulain, Alexa S. Green, Madalina Uzunov, Olivier Kosmider, Isabelle Radford-Weiss, Ivan Cruz Moura, Patrick Auberger, Norbert Ifrah, Valérie Bardet, Nicolas Chapuis, Catherine Lacombe, Patrick Mayeux, Jérôme Tamburini, Didier Bouscary
Journal: Blood
Blood (2013) 122 (20): 3521–3532.
https://doi.org/10.1182/blood-2013-03-493163
Published: 2013
Includes: Supplemental data
Journal Articles

Modulation of Activin Signaling by RAP-011 (ActRIIA-IgG1) Improve Anemia, Increases Hemoglobin Levels and Corrects Ineffective Erythropoiesis in β-Thalassemia

Michael Dussiot, Thiago Maciel, PhD, Aurelie Fricot, Joel Veiga, Etienne Paubelle, Emmanuel Payen, Yves Beuzard, MD, Jean-Antoine Ribeil, MD, PhD, Jean-Benoît Arlet, MD, Genevieve Courtois, PhD, Tom O Daniel, MD, PhD, Rajesh Chopra, MD, PhD, Victoria Sung, Ph.D., Olivier Hermine, MD, PhD, Ivan Cruz Moura, PhD
Journal: Blood
Blood (2012) 120 (21): 247.
https://doi.org/10.1182/blood.V120.21.247.247
Published: 2012
Journal Articles

Association of Deferasirox and Vitamin D Promotes Cell Differentiation and Improves Overall Survival in Acute Myeloid Leukemia (AML) Elderly Patients After Demethylating Agents Failure: A Retrospective Case Control Study

Etienne Paubelle, Felipe Suarez, MD, PhD, Florence Zylbersztejn, Celine Callens, PharmD PhD, Michael Dussiot, Marc Benhamou, Françoise Isnard, MD, Marie T Rubio, MD, PhD, Gandhi Damaj, Norbert C. Gorin, MD, PhD, Jean-Pierre Marolleau, MD, PhD, Ivan Cruz Moura, PhD, Olivier Hermine
Journal: Blood
Blood (2012) 120 (21): 3622.
https://doi.org/10.1182/blood.V120.21.3622.3622
Published: 2012
Journal Articles

Heat Shock Protein 70 Cytosolic Sequestration by Excess of Free Alpha-Globin Chains Is a Key Mechanism of the Ineffective Erythropoiesis in β-Thalassemia Major Patients

Jean-Benoît Arlet, MD, Jean-Antoine Ribeil, MD, PhD, Adonis Hazoumé, PhD, Samuel Demarest, Luba Tchertanov, PhD, Dussiot Michael, Ivan Cruz Moura, PhD, Thiago Maciel, PhD, Christian Auclair, PhD, Olivier Negre, PhD, Philippe Leboulch, MD, Véronique Baudin-creuza, PhD, Carmen Garrido, PhD, Genevieve Courtois, PhD, Olivier Hermine, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 823.
https://doi.org/10.1182/blood.V120.21.823.823
Published: 2012
Journal Articles

Polymeric Immunoglobulin A1 Controls Erythroblast Proliferation and Accelerates Erythropoiesis Recovery in Anemia

Séverine Coulon, PharmD PhD, Michael Dussiot, Damien Grapton, Thiago Maciel, PhD, Pamella Huey Mei Wang, PhD, Celine Callens, PharmD PhD, Bertrand Arnulf, MD, PhD, Patrick Mayeux, Benhamou Marc, Michel Cogné, MD, PhD, Renato Monteiro, MD, PhD, Olivier Hermine, MD, PhD, Ivan Cruz Moura, PhD
Journal: Blood
Blood (2011) 118 (21): 679.
https://doi.org/10.1182/blood.V118.21.679.679
Published: 2011
Journal Articles

The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation

Alexa S. Green, Nicolas Chapuis, Thiago Trovati Maciel, Lise Willems, Mireille Lambert, Christophe Arnoult, Olivier Boyer, Valerie Bardet, Sophie Park, Marc Foretz, Benoit Viollet, Norbert Ifrah, François Dreyfus, Olivier Hermine, Ivan Cruz Moura, Catherine Lacombe, Patrick Mayeux, Didier Bouscary, Jerome Tamburini
Journal: Blood
Blood (2010) 116 (20): 4262–4273.
https://doi.org/10.1182/blood-2010-02-269837
Published: 2010
Includes: Supplemental data
Journal Articles

Proteinase 3, the Wegener autoantigen, is externalized during neutrophil apoptosis: evidence for a functional association with phospholipid scramblase 1 and interference with macrophage phagocytosis

Chahrazade Kantari, Magali Pederzoli-Ribeil, Omid Amir-Moazami, Valérie Gausson-Dorey, Ivan Cruz Moura, Marie-Christine Lecomte, Marc Benhamou, Véronique Witko-Sarsat
Journal: Blood
Blood (2007) 110 (12): 4086–4095.
https://doi.org/10.1182/blood-2007-03-080457
Published: 2007
Includes: Supplemental data