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Journal Articles

Analysis of Tagraxofusp Activity in AML-Pdc As a Single Agent and in Combination with BCL2 Inhibitors

Morgane Boichut, Margaux Poussard, Imane Belakri, Xavier Roussel, Sabeha Biichle, Maxime Fredon, Florian Renosi, Eric Deconinck, Christopher Brooks, Francine Garnache Ottou, Fanny Delettre
Journal: Blood
Blood (2023) 142 (Supplement 1): 2783.
https://doi.org/10.1182/blood-2023-186126
Published: 2023
Journal Articles

Combination Chemotherapy in Patients with Newly Diagnosed Blastic Plasmacytoid Dendritic Cell Neoplasms (BPDCN): First Results of a Prospective French Trial (LpDessai)

Eric Deconinck, Berengere Gruson, Sabeha Biichle, Anne Roggy, Florian Renosi, Thomas Fournet, Maxime Desmarets, Gregory Tio, Tony Marchand, Mikael Roussel, Thibaut Leguay, Jean-Philippe Vial, Francoise Huguet, Francois Vergez, Emilie Chalayer, Khaoula Mahfoudi, Fressia Honeyman, Sebastien Maury, Nicolas Freynet, Caroline Bonmati, Veronique Latger-Cannard, Eve Gehlkopf, Caroline Bret, Damien Roos Weil, Magali Le Garff-Tavernier, Sophie Rigaudeau, Gandhi Laurent Damaj, Edouard Cornet, Remy Gressin, Marie-Christine Jacob, Delphine Martineau, Aguirre Mimoun, Alice Garnier, Marion Eveillard, Alban Villate, Emmanuelle Rault, Fanny Delettre, Francine Garnache Ottou
Journal: Blood
Blood (2023) 142 (Supplement 1): 1516.
https://doi.org/10.1182/blood-2023-173379
Published: 2023
Journal Articles

Spatial Response to Pivekimab Sunirine (IMGN632) In Vivo in a BPDCN Model

Margaux Poussard, Morgane Boichut, Imane Belakri, Sabeha Biichle, Maxime Fredon, Florian Renosi, Francine Garnache Ottou, Krystal Watkins, Callum Mortimer Sloss, Patrick A. Zweidler-McKay, Fanny Delettre
Journal: Blood
Blood (2023) 142 (Supplement 1): 2791.
https://doi.org/10.1182/blood-2023-185602
Published: 2023
Journal Articles

Male-Biased Spliceosome Mutations in Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Impair pDC Activation and Apoptosis

Katsuhiro Togami, MDPhD, Sun Sook Chung, PhD, Vikas Madan, PhD, Christopher M. Kenyon, BS, Lucia Cabal-Hierro, PhD, Justin Taylor, MD, Sunhee Kim, MD, Gabriel K Griffin, MD, Mahmoud Ghandi, Jia Li, PhD, Yvonne Y. Li, PhD, Fanny Angelot-Delletre, PhD, Sabeha Biichle, Michael Seiler, Silvia Buonamici, PhD, Scott B Lovitch, MDPhD, Abner Louissaint, Jr., MD PhD, Elizabeth A Morgan, MD, Fabrice Jardin, MD PhD, Pier Paolo Piccaluga, MD PhD, David M. Weinstock, MD, Peter S. Hammerman, MD PhD, Henry Yang, PhD, Marina Konopleva, MD PhD, Naveen Pemmaraju, MD, Francine Garnache-Ottou, PhD, Omar Abdel-Wahab, MD, H. Phillip Koeffler, MD, Andrew A Lane, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 13–14.
https://doi.org/10.1182/blood-2020-137727
Published: 2020
Journal Articles

A Transcriptomic Continuum of Differentiation Arrest in Acute Leukemia

Jonathan Bond, Aleksandra Krzywon, Ludovic Lhermitte, MD PhD, Christophe Roumier, PharmD, Anne Roggy, Mohamed Belhocine, PhD MSc, BSc, Alexander Kheirallah, Patrick Villarese, PhD, Guillaume Hypolite, Francine Garnache-Ottou, D.Pharm PhD, Herve Dombret, MD PhD, Nicolas Boissel, MD PhD, Claude Preudhomme, PharmD, PhD, Vahid Asnafi, MD PhD, Elisa Laurenti, PhD, Elizabeth Macintyre, PhDMD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2511.
https://doi.org/10.1182/blood-2019-125902
Published: 2019
Journal Articles

LXR agonist treatment of blastic plasmacytoid dendritic cell neoplasm restores cholesterol efflux and triggers apoptosis

Adam Ceroi, David Masson, Anne Roggy, Christophe Roumier, Cécile Chagué, Thierry Gauthier, Laure Philippe, Baptiste Lamarthée, Fanny Angelot-Delettre, Francis Bonnefoy, Sylvain Perruche, Sabeha Biichle, Claude Preudhomme, Elisabeth Macintyre, Laurent Lagrost, Francine Garnache-Ottou, Philippe Saas
Journal: Blood
Blood (2016) 128 (23): 2694–2707.
https://doi.org/10.1182/blood-2016-06-724807
Published: 2016
Includes: Supplemental data
Journal Articles

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Harbors Frequent Splicesosome Mutations That Cause Aberrant RNA Splicing Affecting Genes Critical in pDC Differentiation and Function

Katsuhiro Togami, MD PhD, Vikas Madan, PhD, Jia Li, PhD, Alexandra-Chloe Villani, PhD, Siranush Sarkizova, BS, Mahmoud Ghandi, PhD, Kevin Buczkowski, BS, Yvonne Li, PhD, Sabeha Biichle, BS, Fanny Angelot-Delettre, PhD, Michael Seiler, PhD, Silvia Buonamici, PhD, Justin Taylor, MD, Omar Abdel-Wahab, MD, Peter S Hammerman, MD PhD, Nir Hacohen, PhD, Henry Yang, PhD, Francine Garnache-Ottou, PhD, H. Phillip Koeffler, MD PhD, Andrew A. Lane, MD PhD
Journal: Blood
Blood (2016) 128 (22): 738.
https://doi.org/10.1182/blood.V128.22.738.738
Published: 2016
Journal Articles

Haploinsufficiency for NR3C1 , the gene encoding the glucocorticoid receptor, in blastic plasmacytoid dendritic cell neoplasms

Anouk Emadali, Neda Hoghoughi, Samuel Duley, Azadeh Hajmirza, Els Verhoeyen, Francois-Loic Cosset, Philippe Bertrand, Christophe Roumier, Anne Roggy, Céline Suchaud-Martin, Martine Chauvet, Sarah Bertrand, Sieme Hamaidia, Sophie Rousseaux, Véronique Josserand, Julie Charles, Isabelle Templier, Takahiro Maeda, Juliana Bruder-Costa, Laurence Chaperot, Joel Plumas, Marie-Christine Jacob, Thierry Bonnefoix, Sophie Park, Remy Gressin, Cornelis P. Tensen, Cristina Mecucci, Elizabeth Macintyre, Dominique Leroux, Elisabeth Brambilla, Florence Nguyen-Khac, Isabelle Luquet, Dominique Penther, Christian Bastard, Fabrice Jardin, Christine Lefebvre, Francine Garnache, Mary B. Callanan
Journal: Blood
Blood (2016) 127 (24): 3040–3053.
https://doi.org/10.1182/blood-2015-09-671040
Published: 2016
Includes: Supplemental data
Journal Articles

Liver X Receptor Agonists: A Potential Treatment for Blastic Plasmacytoid Dendritic Cell Neoplasm

Adam Ceroi, PhDSTUDENT, Francine Garnache-ottou, PhD, Anne Roggy, PhDSTUDENT, Fanny Angelot-Delettre, PhD, Laure Philippe, MDcal student, Afag Asgarova, PhDstudent, Francis Bonnefoy, PhD, Cécile Chagué, SM Student, Sabeha Biichle, Jean-Paul Remy-Martin, ING, Claude Preudhomme, MD PhD, Christophe Roumier, MD, Elizabeth Macintyre, MD PhD, Laurent Lagrost, PhD, David Masson, PhD, Philippe Saas, PhD
Journal: Blood
Blood (2015) 126 (23): 4933.
https://doi.org/10.1182/blood.V126.23.4933.4933
Published: 2015
Journal Articles

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Patient-Derived Xenografts Are Faithful Genomic and Phenotypic Models of Primary Leukemia and Respond to the IL3 Receptor Targeting Agent SL-401 In Vivo

Amanda L Christie, B.S., Yvonne Li, PhD, Katsuhiro Togami, MD, Mahmoud Ghandi, PhD, Alexandra N. Christodoulou, M.S., Kevin Buczkowski, Fanny Angelot-Delettre, PhD, Sabeha Biichle, Janice Chen, PhD, Christopher L. Brooks, PhD, David M. Weinstock, MD, Francine Garnache-Ottou, PhD, Peter S Hammerman, MD PhD, Andrew A Lane, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3797.
https://doi.org/10.1182/blood.V126.23.3797.3797
Published: 2015
Journal Articles

Biological Description of 109 Cases of Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) from the French Network of BPDCN

Eve Poret, Fanny Angelot Delettre, Sabeha Biichle, Anne Roogy, Louis Benazet, Maider Pagadoy, Chrystelle Vidal, Franck Leroux, Véronique Harrivel, Christophe Ferrand, PhD, Veronique Salaun, Zehaira Benseddik, Julien Guy, Marie Christine Jacob, Christophe Roumier, Jean Feuillard, Liliana Vila, Lucile Baseggio, Adriana Plesa, Christine Arnoulet, B Benet, Bernard Drenou, MD, Veronique Latger Cannard, Marie-Christine Bene, MD, Michel Ticchioni, Daniel Lusina, Valerie Bardet, Magalie LE Garff Tavernier, Elizabeth Macintyre, MD PhD, Vahid Asnafi, MDPhD, Maria Elena Noguera, Sabrina Bouyer, Carine Lecoq Lafon, Mikael Roussel, MD PhD, Fabrice Jardin, Francoise Solly, MD, Lydia Campos, MD PhD, Anne Galoisy, Anne Arnaud, Sylvie Daliphard, Franck Genevieve, MD PhD, Romaric Lacroix, Françoise Schillinger, Estelle Seilles, Delphine Binda, Eric Deconinck, Philippe Saas, PhD, Francine Garnache Ottou, PhD
Journal: Blood
Blood (2015) 126 (23): 3812.
https://doi.org/10.1182/blood.V126.23.3812.3812
Published: 2015
Journal Articles

How to Treat Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Patients : Results on 86 Patients of the French BPDCN Network

Eve Poret, Chrystelle Vidal, Yohan Desbrosses, Fanny Angelot Delettre, Maider Pagadoy, Aurore Pugin, Louis Benazet, Franck Leroux, Elise Robert, Delphine Binda, Sabeha Biichle, Anne Roggy, PhDSTUDENT, Laure Philippe, MDcal student, Berengere Gruson, Anne-Claire Gac, Michel Maigre, Denis Caillot, Remy Gressin, MD, Pascal Turlure, MD, Anne-Sophie Michallet, MD, Lila Gilis, Veronique Dorvaux, Yazid Arkam, Caroline Bonmati, MD, Pierre Péterlin, Pierre-Simon Rohrlich, MD PhD, Thorsten Braun, MD PhD, jean-Valere Malfuson, Didier Bouscary, MDPhD, Eric Pujade-Lauraine, Felipe Suarez, MD PhD, Carole Soussain, MD, Etienne Lengliné, MD, Mathieu Puyade, MD, Tony Marchand, MD, Denis Guyotat, Bruno Lioure, MD, Christian Recher, MD, Damien Roos-Weil, Fabrice Jardin, Jean-Pierre Marolleau, Bernard Drenou, MD, Bernard Bonnotte, MD PhD, Sophie Dalac, Philippe Saas, PhD, Francine Garnache Ottou, PhD, Eric Deconinck
Journal: Blood
Blood (2015) 126 (23): 456.
https://doi.org/10.1182/blood.V126.23.456.456
Published: 2015
Journal Articles

Proxe: A Public Repository of Xenografts to Facilitate Studies of Biology and Expedite Preclinical Drug Development in Leukemia and Lymphoma

Mark A. Murakami, MD MA, Alexandra N. Christodoulou, M.S., Amanda L Christie, B.S., Tiffany DeSouza, B.S., Abner Louissaint, Jr., MD PhD, Una Vojinovic, B.S., Raphael Koch, MD, Loretta S. Li, MD, Scott P. Kallgren, PhD, Prakash Rao, PhD, Johannes Köster, PhD, Raga Vadhi, M.S., Eilene Duberow, B.S., Elizabeth A. Morgan, MD, Hongjun Wang, Samia S. Ahmed, Katharine L. Majewski, Marina Konopleva, MD PhD, Jerome Tamburini, MD, PhD, Alejandro Gutierrez, MD, Michelle Kelliher, PhD, Julia Etchin, PhD, Irmela Jeremias, MD, Andrew P. Weng, MD PhD, Andrew L Kung, MD PhD, Andrew A Lane, MD PhD, Francine Garnache-Ottou, PhD, Shai Izraeli, MD Prof, Eric Jacobsen, MD, Ilene Galinsky, ANP, Richard M. Stone, MD, Marian H. Harris, MD PhD, David M. Dorfman, MD PhD, Jon C Aster, MDPhD, Henry Long, PhD, Lewis B. Silverman, MD, David M Weinstock, MD
Journal: Blood
Blood (2015) 126 (23): 3252.
https://doi.org/10.1182/blood.V126.23.3252.3252
Published: 2015
Journal Articles

Activity of SL-401, a targeted therapy directed to interleukin-3 receptor, in blastic plasmacytoid dendritic cell neoplasm patients

Clinical Trials & Observations
Arthur E. Frankel, Jung H. Woo, Chul Ahn, Naveen Pemmaraju, Bruno C. Medeiros, Hetty E. Carraway, Olga Frankfurt, Stephen J. Forman, Xuezhong A. Yang, Marina Konopleva, Francine Garnache-Ottou, Fanny Angelot-Delettre, Christopher Brooks, Michael Szarek, Eric Rowinsky
Journal: Blood
Blood (2014) 124 (3): 385–392.
https://doi.org/10.1182/blood-2014-04-566737
Published: 2014
Journal Articles

Preclinical Studies Of SL-401, a Targeted Therapy Directed To The Interleukin-3 Receptor (IL3-R), In Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN): Potent Activity In BPDCN Cell Lines, Primary Tumor, and In An In Vivo Model

Delettre Fanny, PhD, Arthur E. Frankel, MD, Estelle Seilles, PhD, Sabeha Biichle, Bsc, Eric Deconninck, MD, Francis Bonnefoy, PhD, Baptiste Lamarthee, PhD Student, Christopher L. Brooks, PhD, Eric Rowinsky, MD, Philippe Saas, Ph.D., Francine Garnache Ottou, PhD
Journal: Blood
Blood (2013) 122 (21): 3942.
https://doi.org/10.1182/blood.V122.21.3942.3942
Published: 2013
Journal Articles

Blastic plasmacytoid dendritic cell neoplasm

Fanny Angelot-Delettre, Francine Garnache-Ottou
Journal: Blood
Blood (2012) 120 (14): 2784.
https://doi.org/10.1182/blood-2012-03-417030
Published: 2012
Journal Articles

The IL-3Rα-Targeted Drug SL-401 Selectively Kills Blastic Plasmacytoid Dendritic Cell Neoplasm Cells

Fanny Angelot-Delettre, PhD, Arthur E. Frankel, MD, Jen Sing Liu, PhD, Estelle Seilles, PhD, Sabeha Biichle, Bsc, Bernard Drenou, MD, PhD, Mark L. Jacobson, MA, Thomas P. Cirrito, PhD, Arkam Yazid, MD, Eric Deconinck, MD, PhD, Christopher L. Brooks, PhD, Philippe Saas, PhD, Francine Garnache Ottou, PhD
Journal: Blood
Blood (2011) 118 (21): 2588.
https://doi.org/10.1182/blood.V118.21.2588.2588
Published: 2011
Journal Articles

Identification of an alternative CD20 transcript variant in B-cell malignancies coding for a novel protein associated to rituximab resistance

Carole Henry, Marina Deschamps, Pierre-Simon Rohrlich, Jean-René Pallandre, Jean-Paul Rémy-Martin, Mary Callanan, Alexandra Traverse-Glehen, Camille GrandClément, Francine Garnache-Ottou, Remy Gressin, Eric Deconinck, Gilles Salles, Eric Robinet, Pierre Tiberghien, Christophe Borg, Christophe Ferrand
Journal: Blood
Blood (2010) 115 (12): 2420–2429.
https://doi.org/10.1182/blood-2009-06-229112
Published: 2010
Includes: Supplemental data
Journal Articles

Eight Colors Flow Cytometry Phenotyping for Blood Minimal Residual Disease Monitoring in Hairy Cell Leukaemia Patients.

Marie-Olivia Chandesris, Francine Garnache, Ludovic Lhermitte, Kheira Beldjord, Anne-Sophie Bedin, Felipe Suarez, Olivier Hermine, Vahid Asnafi, Bruno Varet, Elizabeth Macintyre
Journal: Blood
Blood (2009) 114 (22): 1609.
https://doi.org/10.1182/blood.V114.22.1609.1609
Published: 2009
Journal Articles

A New Human CD20 Spliced mRNA as a Potential Molecular Marker for the Follow-up of B-Cell Malignancies.

Marina Deschamps, Carole Henry, Eric Robinet, Francine Garnache-Ottou, Jean-Paul Remy-Martin, Christophe Borg, Pierre-Simon Rohrlich, Eric Deconinck, Pierre Tiberghien, Christophe Ferrand
Journal: Blood
Blood (2008) 112 (11): 1479.
https://doi.org/10.1182/blood.V112.11.1479.1479
Published: 2008