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James Neef
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Journal Articles

A phase 1 dose escalation and dose optimization study to evaluate the preliminary safety, tolerability, pharmacokinetic, pharmacodynamic, and clinical activity profile of AUTX703 in participants with relapsed/refractory acute myeloid leukemia and myelodysplastic syndromes

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Stephen Strickland, Eunice Wang, Brian Ball, Alice Mims, Joshua Zeidner, Xin Wang, Rory Shallis, Catherine Lai, Katharine Yen, David Millan, Joseph DeBartolo, James Neef, Laura Antipov, Erika Manyak, Rachael Kendrick, Guangbin Peng, Kimberly Straley, Caroline Almon, Carrie Brownstein, Courtney DiNardo
Journal: Blood
Blood (2025) 146 (Supplement 1): 6952.
https://doi.org/10.1182/blood-2025-6952
Published: 2025
Journal Articles

AUTX703, a Novel and Potent KAT2A and KAT2B Protein Degrader, Induces Differentiation and Offers Survival Advantage in a Primary Human AML Xenograft Model

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Hélène Duparc, James Neef, Janany Kandiah, Maulasri Bhatta, Agathe Chédeville, Joe DeBartolo, Sara Sinicropi-Yao, Betty Chan, Alex Constan, Christophe Marzac, Jean-Baptiste Micol, Laura Antipov, Stephane De Botton, Katharine E Yen, David S Millan, Iléana Antony-Debré, Kimberly S Straley
Journal: Blood
Blood (2024) 144 (Supplement 1): 3585.
https://doi.org/10.1182/blood-2024-208179
Published: 2024