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Journal Articles

Inhibition of Mcl-1 Enhances the Efficacy of Tyrosine Kinase Inhibition in FLT3 Mutated AML and Synergizes with Venetoclax Targeting AML Stem Cells

Bing Z Carter, PhD, Wenjing Tao, Po Yee Mak, Qi Zhang, PhD, Xiangmeng Wang, Vinitha Mary Kuruvilla, MSc, Carli Stewart, Vivian Ruvolo, MS, Venkata Lokesh Battula, PhD, Marina Y Konopleva, MD PhD, Sean Caenepeel, Jude Canon, PhD, Paul Hughes, PK Morrow, Michael Andreeff, MD PhD

Blood (2019) 134 (Supplement_1): 1267.

https://doi.org/10.1182/blood-2019-125725

Published: 2019

Journal Articles

Mcl-1/CDK9 Targeting By AZD5991/AZD4573 Overcomes Intrinsic and Acquired Venetoclax Resistance in Vitro and In Vivo in PDX Model of AML through Modulation of Cell Death and Metabolic Functions

Bing Z Carter, PhD, Po Yee Mak, Wenjing Tao, Mark Warmoes, Philip L Lorenzi, PhD, Duncan Mak, BSc, MPhil, Vivian Ruvolo, MS, Xiangmeng Wang, Huaxian Ma, MS, Hong Mu, MD PhD, Justin Cidado, PhD, Lisa Drew, PhD, Michael Andreeff, MD PhD

Blood (2018) 132 (Supplement 1): 768.

https://doi.org/10.1182/blood-2018-99-113491

Published: 2018

Journal Articles

Targeting Wnt/β-Catenin and BCL-2, Two Critical Survival Factors, Synergistically Induces Apoptosis in AML Via Rac1-Mediated MCL-1 Inhibition

Xiangmeng Wang, Po Yee Mak, Wencai Ma, Xiaoping Su, PhD, Hong Mu, MD PhD, Wenjing Tao, Michael Andreeff, MD PhD, Bing Z Carter, PhD

Blood (2018) 132 (Supplement 1): 1442.

https://doi.org/10.1182/blood-2018-99-118367

Published: 2018

Journal Articles

Novel ARC//IL1β/PGE2/β-Catenin/ARC Circuit Regulates Leukemia and Leukemia Microenvironment and Drug Resistance in AML

Bing Z Carter, PhD, Po Yee Mak, Xiangmeng Wang, PhD, Hong Mu, MD PhD, Wenjing Tao, PhD, Vivian Ruvolo, PhD, Michael Andreeff, MD PhD

Blood (2017) 130 (Supplement 1): 3776.

https://doi.org/10.1182/blood.V130.Suppl_1.3776.3776

Published: 2017

Journal Articles

Combinatorial Inhibition of Focal Adhesion Kinase and BCL-2 in AML

Xiangmeng Wang, PhD, Po Yee Mak, Hong Mu, MD PhD, Wenjing Tao, PhD, Jonathan A Pachter, PhD, David T Weaver, PhD, Bing Xu, Michael Andreeff, MD PhD, Bing Z Carter, PhD

Blood (2017) 130 (Supplement 1): 2653.

https://doi.org/10.1182/blood.V130.Suppl_1.2653.2653

Published: 2017

Journal Articles

Activation of p53 Enhances Antileukemia Activity of Bcr-Abl Tyrosine Kinase Inhibitors in a Murine Model of CML

Bing Z Carter, PhD, Po Yee Mak, Hong Mu, MD PhD, Duncan Mak, Ej Dettman, Michael Cardone, Xiangmeng Wang, PhD, Wendy Schober, Wenjing Tao, PhD, Takahiko Seki, Michael Andreeff, MD PhD

Blood (2017) 130 (Supplement 1): 4170.

https://doi.org/10.1182/blood.V130.Suppl_1.4170.4170

Published: 2017

Journal Articles

Inhibition of FAK Exerts Anti-Leukemic Activity and Potentiates ABT-199-Induced Apoptosis in AML

Xiangmeng Wang, Po Yee Mak, MPhil, Hong Mu, MD PhD, Xuejie Jiang, Duncan Mak, BSc, MPhil, Jonathan A. Pachter, PhD, David T. Weaver, PhD, Bing Xu, PhD, Michael Andreeff, MD PhD, Bing Z Carter, PhD

Blood (2016) 128 (22): 1574.

https://doi.org/10.1182/blood.V128.22.1574.1574

Published: 2016

Journal Articles

A New Strategy to Target Acute Myeloid Leukemia Stem and Progenitor Cells Using Chidamide, a Histone Deacetylase Inhibitor

Bing Xu, PhD, Yin Li, Kai Chen, Yong Zhou, Yiren Xiao, Manman Deng, Zhiwu Jiang, Wei Ye, Xinru Wei, Xiangmeng Wang, Jie Li, Jiabao Liang, Zhongxin Zheng, Yao Yao, MD, Weiguang Wang, Peng Li, PhD

Blood (2015) 126 (23): 4925.

https://doi.org/10.1182/blood.V126.23.4925.4925

Published: 2015

Journal Articles

KLF4 induces apoptosis in T-ALL through the BCL2/BCLXL pathway

Bing Xu, MD, Xiangmeng Wang, MD, Peng Li, PhD, Wei Li, MD, Huijuan Dong, MD, Yong Zhou, MD, Yanyan Li, MD

Blood (2013) 122 (21): 4902.

https://doi.org/10.1182/blood.V122.21.4902.4902

Published: 2013

Journal Articles

Identification of secreted proteins that can promote erythroid progenitor expansion

Bing Xu, MD, Xiangmeng Wang, MD, Peng Li, PhD, Yiren Xiao, MD, Huijuan Dong, MD, Yong Zhou, MD, Yanyan Li, MD

Blood (2013) 122 (21): 4864.

https://doi.org/10.1182/blood.V122.21.4864.4864

Published: 2013

NARROW

Inhibition of Mcl-1 Enhances the Efficacy of Tyrosine Kinase Inhibition in FLT3 Mutated AML and Synergizes with Venetoclax Targeting AML Stem Cells

Mcl-1/CDK9 Targeting By AZD5991/AZD4573 Overcomes Intrinsic and Acquired Venetoclax Resistance in Vitro and In Vivo in PDX Model of AML through Modulation of Cell Death and Metabolic Functions

Targeting Wnt/β-Catenin and BCL-2, Two Critical Survival Factors, Synergistically Induces Apoptosis in AML Via Rac1-Mediated MCL-1 Inhibition

Novel ARC//IL1β/PGE2/β-Catenin/ARC Circuit Regulates Leukemia and Leukemia Microenvironment and Drug Resistance in AML

Combinatorial Inhibition of Focal Adhesion Kinase and BCL-2 in AML

Activation of p53 Enhances Antileukemia Activity of Bcr-Abl Tyrosine Kinase Inhibitors in a Murine Model of CML

Inhibition of FAK Exerts Anti-Leukemic Activity and Potentiates ABT-199-Induced Apoptosis in AML

A New Strategy to Target Acute Myeloid Leukemia Stem and Progenitor Cells Using Chidamide, a Histone Deacetylase Inhibitor

KLF4 induces apoptosis in T-ALL through the BCL2/BCLXL pathway

Identification of secreted proteins that can promote erythroid progenitor expansion

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American Society of Hematology

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American Society of Hematology

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