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Journal Articles

High-Dose Targeted Radiation with 131 I-Apamistamab Prior to HCT Demonstrated a Dose-Response for Durable Complete Remission in Patients with R/R AML

Mark R. Litzow, George Chen, Boglarka Gyurkocza, Rajneesh Nath, Stuart Seropian, Hannah Choe, Camille N. Abboud, Nebu Koshy, Ben K. Tomlinson, Sunil Abhyankar, James M. Foran, Sameem Abedin, Zaid Al-Kadhimi, Partow Kebriaei, Mitchell Sabloff, Johnnie J. Orozco, Katarzyna Joanna Jamieson, Margarida Magalhaes-Silverman, Koen Van Besien, Michael W. Schuster, Arjun D. Law, Sebastian A. Mayer, Hillard M. Lazarus, Eugene Leung, Ming-Kai Chen, Mona Natwa, Jennifer Spross, Kate L Li, Norman Nagl, Elaina Haeuber, Madhuri Vusirikala, Akash Nahar, Brenda M. Sandmaier, John Pagel, Sergio A. Giralt, Avinash Desai, Richard L. Wahl, Neeta Pandit-Taskar, Patrik Brodin, Patrick J. Stiff
Journal: Blood
Blood (2023) 142 (Supplement 1): 3529.
https://doi.org/10.1182/blood-2023-189040
Published: 2023
Journal Articles

The Dynamic Evolution of Bone Marrow Adipocytes during Acute Lymphoblastic Leukemia Pathogenesis and Therapy

Xi Jia, Naying Liao, Xinyuan Chen, Yunqian Yao, Kai Chen, Pengcheng Shi
Journal: Blood
Blood (2022) 140 (Supplement 1): 11525.
https://doi.org/10.1182/blood-2022-166276
Published: 2022
Journal Articles

Outcomes of Thromboembolism in COVID-19 Cancer Patients Vs Non-Cancer Patients

Can Jones, Kristina Menchaca, Catherine Ostos, Jeffery Durbin, Kai Chen, Shachar Peles
Journal: Blood
Blood (2022) 140 (Supplement 1): 5660.
https://doi.org/10.1182/blood-2022-157218
Published: 2022
Journal Articles

S100A9 Contributes to T Cell Dysfunction through Its Interaction with RAGE in MDS

Wendy Kandell, BS, Thu Le Trinh, PhD, Xianghong Chen, PhD, Pingyan Cheng, MD, Danielle Gilvary, BS, Yin-Kai Chen, MD, Alexandra Calescibetta, Erika Adriana Eksioglu, MS PhD, Alan F. List, MD, Sheng Wei, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4228.
https://doi.org/10.1182/blood-2019-128717
Published: 2019
Journal Articles

Simultaneous Inhibition of Mcl-1 and Induction of DNA Damage Accumulation By Chidamide, a Novel Selective HDACi, Potentiates the Cytotoxicity of ABT-199 in Acute Myeloid Leukemia

Bing Xu, Kai Chen, Qianying Yang, Jie Zha, Haijun Zhao, Liying Feng, Xiaolei Chen, Guo Fu, Ken H. Young, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5767.
https://doi.org/10.1182/blood-2019-121721
Published: 2019
Journal Articles

Dysregulation of Splicing Patterns in MDS Induced By the S100A9/Fto Axis

Erika Adriana Eksioglu, MS PhD, Ling Cen, PhD, Xianghong Chen, PhD, Pingyan Cheng, MD, Kenneth Wright, PhD, Thu Le Trinh, PhD, Danielle Gilvary, BS, Wendy Kandell, BS, Jinhong Liu, MD, Yin-Kai Chen, MD, Amy F McLemore, M.S., Alexandra Calescibetta, John Cleveland, PhD, Alan F. List, MD, Sheng Wei, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4215.
https://doi.org/10.1182/blood-2019-128434
Published: 2019
Journal Articles

Genome Editing of the Bcl11A Erythroid Specific Enhancer in Bone Marrow Derived Hematopoietic Stem and Progenitor Cells for the Treatment of Sickle Cell Disease

Siyuan Tan, PhD, Kai-Hsin Chang, PhD, Sarah Smith, BS, Kai Chen, MS, Timonthy Sullivan, BS, Qianhe Zhou, PhD, Andreas Reik, PhD, Fyodor D Urnov, PhD, Edward J. Rebar, PhD, Olivier Danos, PhD, Haiyan Jiang, PhD
Journal: Blood
Blood (2015) 126 (23): 203.
https://doi.org/10.1182/blood.V126.23.203.203
Published: 2015
Journal Articles

Role of Mitochondrial Apoptotic Pathway in Disulfiram/Copper Mixture-Induced Cell Apoptosis in Human B-Lineage Acute Lymphoblastic Leukemia in Vitro

Bing Xu, PhD, Manman Deng, Zhiwu Jiang, Jie Li, Kai Chen, Peng Li, PhD
Journal: Blood
Blood (2015) 126 (23): 4920.
https://doi.org/10.1182/blood.V126.23.4920.4920
Published: 2015
Journal Articles

Disulfiram Combined with Copper Induces Acute Myeloid Leukemic Stem-like KG1a Cell Apoptosis through TNF-a/ROS Pathway

Bing Xu, PhD, Yong Zhou, Manman Deng, Wenbin Zhong, Kai Chen, Huijuan Dong, Daoguang Yan, Shuyun Zhou
Journal: Blood
Blood (2015) 126 (23): 4923.
https://doi.org/10.1182/blood.V126.23.4923.4923
Published: 2015
Journal Articles

A New Strategy to Target Acute Myeloid Leukemia Stem and Progenitor Cells Using Chidamide, a Histone Deacetylase Inhibitor

Bing Xu, PhD, Yin Li, Kai Chen, Yong Zhou, Yiren Xiao, Manman Deng, Zhiwu Jiang, Wei Ye, Xinru Wei, Xiangmeng Wang, Jie Li, Jiabao Liang, Zhongxin Zheng, Yao Yao, MD, Weiguang Wang, Peng Li, PhD
Journal: Blood
Blood (2015) 126 (23): 4925.
https://doi.org/10.1182/blood.V126.23.4925.4925
Published: 2015
Journal Articles

Clonal Analysis of Human Bone Marrow CD34+ Cells Edited By BCL11A-Targeting Zinc Finger Nucleases Reveals Clinically Relevant Levels of Fetal Globin Expression in Edited Erythroid Progeny

Kai-Hsin Chang, PhD, Timothy Sullivan, MS, Mei Liu, BS, Xiao Yang, PhD, Chao Sun, PhD, Benjamin Vieira, BS, Ming Zhang, PhD, Vu P. Hong, PhD, Kai Chen, MS, Sarah Smith, BS, Siyuan Tan, PhD, Andreas Reik, PhD, Fyodor D Urnov, PhD, Edward J. Rebar, PhD, Olivier Danos, PhD, Haiyan Jiang, PhD
Journal: Blood
Blood (2015) 126 (23): 3234.
https://doi.org/10.1182/blood.V126.23.3234.3234
Published: 2015
Journal Articles

Enhancing the Acute Hemostatic Efficacy in Cynomolgus Monkeys By Targeting Activated Coagulation Factor VII to Platelets

Siyuan Tan, PhD, Joe Salas, PhD, Kai Chen, Tamera Ashworth, Sarah Smith, Elena Kistanova, Nancy Moore, Marisol Acosta, Anxhela Kole, David R. Light, PhD, Robert Peters, PhD, Haiyan Jiang, PhD
Journal: Blood
Blood (2014) 124 (21): 1488.
https://doi.org/10.1182/blood.V124.21.1488.1488
Published: 2014
Journal Articles

An Immunodeficient Mouse Model With Circulating Human Platelets To Evaluate The Platelet Clearance and Pharmacokinetics Of Platelet-Targeted Coagulation Factor VIIa

Siyuan Tan, PhD, Kai Chen, MS, Joe Salas, Ph.D., Robert Peters, Ph.D., David R. Light, PhD, Haiyan Jiang, PhD
Journal: Blood
Blood (2013) 122 (21): 2345.
https://doi.org/10.1182/blood.V122.21.2345.2345
Published: 2013
Journal Articles

Different Contribution of Hematopoietic and Somatic Cell Types Expressing FcRn to the Prolonged Half-Life of Recombinant Factor VIII Fc and Recombinant FIX Fc

Arjan van der Flier, PhD, Zhan Liu, Douglas Drager, Sebastien Vallee, PhD, Kai Chen, Siyuan Tan, PhD, Keith Wharton, MD, PhD, David R. Light, PhD, Haiyan Jiang, PhD
Journal: Blood
Blood (2012) 120 (21): 1103.
https://doi.org/10.1182/blood.V120.21.1103.1103
Published: 2012
Journal Articles

Cellular Uptake of rFVIIIFc in Liver Is Primarily Contributed by Sinusoidal Endothelial Cells.

Siyuan Tan, PhD, Kai Chen, Arjan van der Flier, PhD, Zhan Liu, David R. Light, PhD, Haiyan Jiang, PhD
Journal: Blood
Blood (2012) 120 (21): 2219.
https://doi.org/10.1182/blood.V120.21.2219.2219
Published: 2012