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Sebastien Anguille
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Journal Articles

The Phase 2 CARTITUDE-2 Trial: Updated Efficacy and Safety of Ciltacabtagene Autoleucel in Patients with Multiple Myeloma and 1-3 Prior Lines of Therapy (Cohort A) and with Early Relapse after First Line Treatment (Cohort B)

Jens Hillengass, Adam D. Cohen, Mounzer E Agha, Michel Delforge, Tessa Kerre, Wilfried Roeloffzen, Hermann Einsele, Hartmut Goldschmidt, Katja Weisel, Marc S. Raab, Christof Scheid, Sebastien Anguille, Pieter Sonneveld, Sonja Zweegman, Jordan M. Schecter, Kevin C De Braganca, Carolyn Chang Jackson, Philip Vlummens, Helen Varsos, Christina Corsale, Deepu Madduri, Tzu-min Yeh, Pankaj Mistry, Tito Roccia, Qingxuan Song, Muhammad Akram, Octavio Costa Filho, Dong Geng, Yael C. Cohen, Niels W.C.J. Van De Donk
Journal: Blood
Blood (2023) 142 (Supplement 1): 1021.
https://doi.org/10.1182/blood-2023-178882
Published: 2023
Journal Articles

Rationale for and Design of Papilio-1: A Phase 1/2, Multicenter, Open-Label Study to Evaluate the Feasibility, Safety, and Efficacy of Point-of-Care-Manufactured Anti-B-Cell Maturation Antigen Chimeric Antigen Receptor T Cells (GLPG5301) in Relapsed/Refractory Multiple Myeloma

Niels W.C.J. van de Donk, Sébastien Anguille, Jo Caers, Marte C. Liefaard, Christian Jacques, Anna D.D. van Muyden
Journal: Blood
Blood (2023) 142 (Supplement 1): 4859.
https://doi.org/10.1182/blood-2023-189001
Published: 2023
Journal Articles

Seven-Day Vein-to-Vein Point-of-Care Manufactured CD19 CAR T Cells (GLPG5101) in Relapsed/Refractory NHL: Results from the Phase 1 Atalanta-1 Trial

Marie José Kersten, Kirsten Saevels, Yves Beguin, Joost S.P Vermaat, Nadia Verbruggen, Maike Spoon, Marte C. Liefaard, Margot Pont, Anna D.D. van Muyden, Maria T. Kuipers, Sébastien Anguille
Journal: Blood
Blood (2023) 142 (Supplement 1): 2113.
https://doi.org/10.1182/blood-2023-172736
Published: 2023
Journal Articles

Talquetamab + Pomalidomide in Patients with Relapsed/Refractory Multiple Myeloma: Safety and Preliminary Efficacy Results from the Phase 1b MonumenTAL-2 Study

Jeffrey Matous, Noa Biran, Aurore Perrot, Jésus G Berdeja, Kathleen Dorritie, Janine Van Elssen, Emma Searle, Cyrille Touzeau, Sébastien Anguille, Deeksha Vishwamitra, Ashley Nguyen, Debopriya Ghosh, Elizabeth Shearin, Katherine Thornton, Damiette Smit, Hang Quach
Journal: Blood
Blood (2023) 142 (Supplement 1): 1014.
https://doi.org/10.1182/blood-2023-187706
Published: 2023
Journal Articles

Updated Results of Talquetamab, a GPRC5D×CD3 Bispecific Antibody, in Patients with Relapsed/Refractory Multiple Myeloma with Prior Exposure to T-Cell Redirecting Therapies: Results of the Phase 1/2 MonumenTAL-1 Study

Andrzej J Jakubowiak, Sebastien Anguille, Lionel Karlin, Ajai Chari, Carolina Schinke, Leo Rasche, Jesus San-Miguel, Michela Campagna, Brandi W Hilder, Tara J Masterson, Xiang Qin, Thomas Renaud, Jaszianne Tolbert, Deeksha Vishwamitra, Sheri Skerget, Philippe Moreau
Journal: Blood
Blood (2023) 142 (Supplement 1): 3377.
https://doi.org/10.1182/blood-2023-187242
Published: 2023
Journal Articles

Teclistamab in Combination with Subcutaneous Daratumumab and Lenalidomide in Patients with Multiple Myeloma: Results from One Cohort of MajesTEC-2, a Phase1b, Multicohort Study

Emma Searle, Hang Quach, Sandy W. Wong, Luciano J. Costa, Cyrille Hulin, Wojciech Janowski, Jesus Berdeja, Sébastien Anguille, Jeffrey V. Matous, Cyrille Touzeau, Anne-Sophie Michallet, Marla Husnik, Deeksha Vishwamitra, Zhuolu Niu, Julie Larsen, Lingling Chen, Jenna D. Goldberg, Rakesh Popat, Andrew Spencer
Journal: Blood
Blood (2022) 140 (Supplement 1): 394–396.
https://doi.org/10.1182/blood-2022-159711
Published: 2022
Journal Articles

Ciltacabtagene Autoleucel (Cilta-cel), a BCMA-Directed CAR-T Cell Therapy, in Patients with Multiple Myeloma (MM) and Early Relapse after Initial Therapy: CARTITUDE-2 Cohort B 18-Month Follow-up

Niels WCJ Van De Donk, Mounzer Agha, Adam D Cohen, Yael C Cohen, Sébastien Anguille, Tessa Kerre, Wilfried W.H. Roeloffzen, Jordan M Schecter, Kevin C De Braganca, Carolyn C Jackson, Helen Varsos, Pankaj Mistry, Tito Roccia, Xiaoying Xu, Katherine Li, Enrique Zudaire, Christina Corsale, Muhammad Akram, Dong Geng, Lida Pacaud, Pieter Sonneveld, Sonja Zweegman
Journal: Blood
Blood (2022) 140 (Supplement 1): 7536–7537.
https://doi.org/10.1182/blood-2022-159169
Published: 2022
Journal Articles

Initial Clinical Results of Atalanta-1, a Phase I/II Trial of Point-of-Care Manufactured GLPG5102 (19CP02) in RR NHL

Sébastien Anguille, Ilse Kuipers, Kirsten Saevels, Yves Beguin, Anna Van Muyden, Christian Jacques, Marie Jose Kersten
Journal: Blood
Blood (2022) 140 (Supplement 1): 10323–10324.
https://doi.org/10.1182/blood-2022-163830
Published: 2022
Journal Articles

Immunicy-1: Targeting BCMA with Cyad-211 to Establish Proof of Concept of an shRNA-Based Allogeneic CAR T Cell Therapy Platform

Ahmad-Samer Al-Homsi, Sebastien Anguille, Dries Deeren, Taiga Nishihori, Nathalie Meuleman, Maher Abdul-Hay, Gareth J. Morgan, Jason Brayer, Nathalie Braun, Caroline Lonez, Marie-Sophie Dheur, Erik Alcantar-Orozco, David Gilham, Anne Flament, Frédéric F. Lehmann
Journal: Blood
Blood (2021) 138 (Supplement 1): 2817.
https://doi.org/10.1182/blood-2021-147738
Published: 2021
Journal Articles

Real-World Outcomes for Standard-of-Care Treatments in Patients with Relapsed/Refractory Multiple Myeloma

Michel Delforge, Marie-Christiane Vekemans, Sébastien Anguille, Julien Depaus, Nathalie Meuleman, Ann Van de Velde, Isabelle Vande Broek, Danielle Strens, Sandra Van Hoorenbeeck, Evelien J Moorkens, Joris Diels, Francesca Ghilotti, Sander Dalhuisen, Sophie Vandervennet
Journal: Blood
Blood (2021) 138 (Supplement 1): 4075.
https://doi.org/10.1182/blood-2021-146250
Published: 2021
Journal Articles

CARTITUDE-2: Efficacy and Safety of Ciltacabtagene Autoleucel, a B-Cell Maturation Antigen (BCMA)-Directed Chimeric Antigen Receptor T-Cell Therapy, in Patients with Multiple Myeloma and Early Relapse after Initial Therapy

Niels W.C.J. Van de Donk, Michel Delforge, Mounzer Agha, Adam D Cohen, Yael C Cohen, Jens Hillengass, Sebastien Anguille, Tessa Kerre, Wilfried Roeloffzen, Jordan M. Schecter, Kevin C. De Braganca, Helen Varsos, Liwei Wang, Martin Vogel, Enrique Zudaire, Christina Corsale, Muhammad Akram, Dong Geng, Tonia Nesheiwat, Lida Pacaud, Pieter Sonneveld, Sonja Zweegman
Journal: Blood
Blood (2021) 138 (Supplement 1): 2910.
https://doi.org/10.1182/blood-2021-146074
Published: 2021
Journal Articles

Clinical Development of a Non-Gene-Edited Allogeneic Bcma-Targeting CAR T-Cell Product in Relapsed or Refractory Multiple Myeloma

A. Samer Al-Homsi, MD, Sebastien Anguille, MD, Jason Brayer, PhDMD, Dries Deeren, MD PhD, Nathalie Meuleman, PhD MD, Gareth Morgan, MDPhDFRCP, Taiga Nishihori, MD, Panagiota A. Sotiropoulou, PhD, Laure Twyffels, PhD, Jennifer Bolsee, PhD, Nathalie Braun, Caroline Lonez, PhD, David E Gilham, PhD, Anne Flament, MD, Frédéric F. Lehmann, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 27–28.
https://doi.org/10.1182/blood-2020-139516
Published: 2020
Journal Articles

Phase 1 Studies Assessing the Safety and Clinical Activity of Multiple Doses of a NKG2D-Based CAR-T Therapy, Cyad-01, in Acute Myeloid Leukemia

Jason B. Brayer, PhDMD, David A Sallman, MD, Tessa Kerre, MD, Xavier Poire, MD, Violaine Havelange, Philippe Lewalle, MD, Eunice S. Wang, MD, Dominik Selleslag, MD, Sebastien Anguille, MD, Yves Beguin, MD PhD, Enkhtsetseg Purev, MD PhD, Ahmad-Samer Al-Homsi, MD, Doreen Dekker, PhD, Eytan Breman, Panagiota A. Sotiropoulou, PhD, Sarah Snykers, PhD, Nathalie Braun, Caroline Lonez, PhD, Bikash Verma, MD DVM, Frédéric F. Lehmann, MD, Marco L. Davila, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1398.
https://doi.org/10.1182/blood-2018-99-114747
Published: 2018
Journal Articles

Dendritic cell vaccination as postremission treatment to prevent or delay relapse in acute myeloid leukemia

Clinical Trials & Observations
Sébastien Anguille, Ann L. Van de Velde, Evelien L. Smits, Viggo F. Van Tendeloo, Gunnar Juliusson, Nathalie Cools, Griet Nijs, Barbara Stein, Eva Lion, Ann Van Driessche, Irma Vandenbosch, Anke Verlinden, Alain P. Gadisseur, Wilfried A. Schroyens, Ludo Muylle, Katrien Vermeulen, Marie-Berthe Maes, Kathleen Deiteren, Ronald Malfait, Emma Gostick, Martin Lammens, Marie M. Couttenye, Philippe Jorens, Herman Goossens, David A. Price, Kristin Ladell, Yoshihiro Oka, Fumihiro Fujiki, Yusuke Oji, Haruo Sugiyama, Zwi N. Berneman
Journal: Blood
Blood (2017) 130 (15): 1713–1721.
https://doi.org/10.1182/blood-2017-04-780155
Published: 2017
Includes: Supplemental data
Journal Articles

Vaccination with WT1 mRNA-Electroporated Dendritic Cells: Report of Clinical Outcome in 66 Cancer Patients

Zwi N. Berneman, Ann L. Van de Velde, Yannick Willemen, Sébastien Anguille, Kirsten Saevels, Paul Germonpré, Manon T. Huizing, Marc Peeters, Annemie Snoeckx, Paul Parizel, Viggo F Van Tendeloo, Eva Lion, Griet Nijs, Barbara Stein, Katrien Vermeulen, Marie-Berthe Maes, Ronald Malfait, Inge Vrelust, Anke Verlinden, Alain P. Gadisseur, Wilfried A Schroyens, Martin Lammens, Evelien L. Smits
Journal: Blood
Blood (2014) 124 (21): 310.
https://doi.org/10.1182/blood.V124.21.310.310
Published: 2014
Journal Articles

Cost Analysis of Immunotherapy Using Dendritic Cells for Acute Myeloid Leukemia Patients

Ann L. Van de Velde, Sébastien Anguille, Philippe Beutels, PhD, Suzy Dom, Ingrid Cornille, Griet Nijs, Viggo F Van Tendeloo, Evelien L. Smits, Anke Verlinden, Alain P. Gadisseur, Wilfried A Schroyens, Zwi N Berneman, MD PhD
Journal: Blood
Blood (2014) 124 (21): 1322.
https://doi.org/10.1182/blood.V124.21.1322.1322
Published: 2014
Journal Articles

Prevention Of Relapse In Acute Myeloid Leukemia By Dendritic Cell Vaccination: Report on a Phase II Study With 29 Patients

Zwi N. Berneman, MD, PhD, FRCP, Ann Van de Velde, MD, Sébastien Anguille, MD, Yannick Willemen, MD, Wilfried A. Schroyens, MD, PhD, Alain P. Gadisseur, MD, PhD, Inge Vrelust, MD, Griet Nijs, MT, Barbara Stein, MSc, Nathalie Cools, PhD, Ronald Malfait, MD, Marie-Berthe Maes, PharmD, PhD, Katrien Vermeulen, PhD, Viggo F. Van Tendeloo, PhD, Evelien L. Smits, PhD
Journal: Blood
Blood (2013) 122 (21): 236.
https://doi.org/10.1182/blood.V122.21.236.236
Published: 2013
Journal Articles

Human plasmacytoid dendritic cells are equipped with antigen-presenting and tumoricidal capacities

Jurjen Tel, Evelien L. Smits, Sébastien Anguille, Rubin N. Joshi, Carl G. Figdor, I. Jolanda M. de Vries
Journal: Blood
Blood (2012) 120 (19): 3936–3944.
https://doi.org/10.1182/blood-2012-06-435941
Published: 2012
Includes: Supplemental data