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Damian J Green
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Journal Articles

Single-cell analysis of the multiple myeloma microenvironment after gamma-secretase inhibition and CAR T-cell therapy

David G Coffey, Pinar Ataca Atilla, Erden Atilla, Ola Landgren, Andrew J Cowan, Sylvain Simon, Margot Pont, Melissa L. Comstock, Geoffrey R Hill, Stanley R. Riddell, Damian J Green
Journal: Blood
Blood blood.2024025231.
https://doi.org/10.1182/blood.2024025231
Published: 2024
Includes: Supplemental data
Journal Articles

Human herpesvirus 6 reactivation and disease are infrequent in chimeric antigen receptor T-cell therapy recipients

Clinical Trials & Observations Brief Report
Eleftheria Kampouri, Elizabeth M. Krantz, Hu Xie, Sarah S. Ibrahimi, Erika S. Kiem, Mandeep K. Sekhon, Emily C. Liang, Andrew J. Cowan, Andrew Portuguese, Damian J. Green, Aya Albittar, Jennifer J. Huang, Jordan Gauthier, Ailyn C. Pérez-Osorio, Keith R. Jerome, Danielle M. Zerr, Michael J. Boeckh, Joshua A. Hill
Journal: Blood
Blood (2024) 144 (5): 490–495.
https://doi.org/10.1182/blood.2024024145
Published: 2024
Includes: Supplemental data
Journal Articles

Regulatory T cells suppress myeloma-specific immunity during autologous stem cell mobilization and transplantation

Shuichiro Takahashi, Simone A. Minnie, Kathleen S. Ensbey, Christine R. Schmidt, Tomoko Sekiguchi, Samuel R. W. Legg, Ping Zhang, Motoko Koyama, Stuart D. Olver, Alika D. Collinge, Sara Keshmiri, Melissa L. Comstock, Antiopi Varelias, Damian J. Green, Geoffrey R. Hill
Journal: Blood
Blood (2024) 143 (16): 1656–1669.
https://doi.org/10.1182/blood.2023022000
Published: 2024
Includes: Supplemental data
Journal Articles

Impact of Gamma-Secretase Inhibition on the Multiple Myeloma Immune Microenvironment

David Coffey, Ola Landgren, Andrew J. Cowan, Pinar Ataca Atilla, Sylvain Simon, Margot Pont, Melissa L Comstock, Geoffrey R Hill, Stanley R. Riddell, Damian J Green
Journal: Blood
Blood (2023) 142 (Supplement 1): 4683.
https://doi.org/10.1182/blood-2023-186980
Published: 2023
Journal Articles

Machine Learning-Based Time-Series Clustering Identifies Archetypal Trajectories of Hematotoxicity after CAR T-Cell Therapy

Emily C Liang, Aya Albittar, Andrew J Portuguese, Jennifer J. Huang, Qian Wu, Joseph De Los Reyes, Nikki Pin, Aiko Torkelson, Delaney Kirchmeier, Abigail Chutnik, Barbara Pender, Joshua A. Hill, Rahul Banerjee, Andrew J. Cowan, Damian J Green, Ajay K Gopal, Christina Poh, Mazyar Shadman, Alexandre V Hirayama, Brian G Till, Erik L Kimble, Lorenzo Iovino, Aude G Chapuis, Folashade Otegbeye, Ryan D Cassaday, Filippo Milano, David G Maloney, Jordan Gauthier
Journal: Blood
Blood (2023) 142 (Supplement 1): 2143.
https://doi.org/10.1182/blood-2023-174106
Published: 2023
Journal Articles

BCMA-Directed Low Dose Alpha-Emitter Therapy Eliminates Minimal Residual Disease in a Multiple Myeloma Mouse Xenograft Model

Melissa L Comstock, Shyril O'Steen, Yukang Lin, Donald Hamlin, D Scott Wilbur, Johnnie J. Orozco, Rainer F. Storb, Roland B. Walter, Pinar Ataca Atilla, Brian G Till, Geoffrey R Hill, Brenda M. Sandmaier, Damian J Green
Journal: Blood
Blood (2023) 142 (Supplement 1): 53.
https://doi.org/10.1182/blood-2023-188055
Published: 2023
Journal Articles

Resistance to CD38 Antigen Targeted Therapy in Multiple Myeloma May Result from Underrecognized Chromosome 4 Gene Deletions

Andrew J Portuguese, Min Fang, Sherilyn A. Tuazon, Margot Pont, Xiaoyu Qu, Carolyn Shasha, Melissa L Comstock, Justina Lyons, Gabriel Cole, Evan W. Newell, Emily Glynn, Lorinda Soma, Damian J Green
Journal: Blood
Blood (2023) 142 (Supplement 1): 1976.
https://doi.org/10.1182/blood-2023-186688
Published: 2023
Journal Articles

Trogocytosis May Attenuate the Efficacy of Anti-BCMA CAR T Cells Administered in Combination with γ-Secretase Inhibitor

Pinar Ataca Atilla, Sylvain Simon, Erden Atilla, Melissa L Comstock, Andrew J. Cowan, Geoffrey R Hill, Stanley R. Riddell, Damian J Green
Journal: Blood
Blood (2023) 142 (Supplement 1): 2083.
https://doi.org/10.1182/blood-2023-187132
Published: 2023
Journal Articles

A Phase 2 Study of Nivolumab for Relapsed/Refractory Multiple Myeloma or Non-Hodgkin Lymphoma Following CAR-T Therapy

Rahul Banerjee, Ryan C Lynch, Qian Wu, Sylvain Simon, Chaitra S Ujjani, Brian G Till, Natalie Wuliji, Daria Gausman, Joshua Dizon, Mary L. Kwok, Sarah S. Lee, Rebecca Silbermann, Eva Medvedova, David G Maloney, Jorge Daniel Ramos, Mazyar Shadman, Jordan Gauthier, Cameron J. Turtle, Ajay K Gopal, Damian J Green, Stanley R. Riddell, Andrew J. Cowan
Journal: Blood
Blood (2023) 142 (Supplement 1): 3509.
https://doi.org/10.1182/blood-2023-173202
Published: 2023
Journal Articles

Long-term Follow-up of CD20-directed Chimeric Antigen Receptor Adoptive T-cell Therapy

George Mo, Sang Yun Lee, David G. Coffey, Valentin Voillet, IIan Kirsch, Damian J. Green, Raphael Gottardo, David G. Maloney, Oliver W. Press, Brian G. Till
Journal: Blood
Blood (2022) 140 (Supplement 1): 7460–7461.
https://doi.org/10.1182/blood-2022-159664
Published: 2022
Journal Articles

Timing of PD-L1 Blockade with Durvalumab May Affect Outcomes of CD19 CAR-T Cell Therapy for Relapsed/Refractory Large B-Cell Lymphoma

Alexandre Vinaud Hirayama, Salvatore Fiorenza, Jordan Gauthier, Jenna M. Voutsinas, Qian Vicky Wu, Erik L. Kimble, Barbara S. Pender, Delaney R. Kirchmeier, Henna A. Di, Ryan D. Cassaday, Aude G. Chapuis, Damian J. Green, Hans-Peter Kiem, Filippo Milano, Mazyar Shadman, Brian G. Till, Stanley R. Riddell, David G. Maloney, Cameron J. Turtle
Journal: Blood
Blood (2022) 140 (Supplement 1): 7447–7449.
https://doi.org/10.1182/blood-2022-168185
Published: 2022
Journal Articles

Regulatory T Cell Depletion during Stem Cell Mobilization Enhances Anti-Myeloma Immunity after Experimental Autologous Stem Cell Transplantation

Shuichiro Takahashi, Simone A Minnie, Samuel RW Legg, Christine R Schmidt, Kathleen S Ensbey, Damian J. Green, Geoffrey R Hill
Journal: Blood
Blood (2022) 140 (Supplement 1): 2086–2087.
https://doi.org/10.1182/blood-2022-168117
Published: 2022
Journal Articles

Sea-BCMA Mono- and Combination Therapy in Patients with Relapsed/Refractory Multiple Myeloma: Updated Results of a Phase 1 Study (SGNBCMA-001)

James E. Hoffman, Brea Lipe, Jason Melear, Michaela Liedtke, Mark A. Schroeder, Ruben Niesvizky, Christopher Strouse, Christopher A. Yasenchak, Damian J. Green, Jeremy Sauer, Yinghui Wang, Phoenix Ho, Al-Ola Abdallah
Journal: Blood
Blood (2022) 140 (Supplement 1): 10160–10162.
https://doi.org/10.1182/blood-2022-157347
Published: 2022
Journal Articles

Plasma Cell Leukemia: A Multicenter Retrospective Study of 130 Patients

Iloabueke Chineke, Betsy Wertheim, Denise Roe, Ashley Larsen, Victoria A. Vardell, Douglas W. Sborov, Damian J. Green, Michaela Liedtke, Marie Okoniewski, Mohammed Wazir, Omar Nadeem, Levanto Schachter, David Coffey, Krisstina L. Gowin, Dominique DeGraaff
Journal: Blood
Blood (2022) 140 (Supplement 1): 7144–7146.
https://doi.org/10.1182/blood-2022-164713
Published: 2022
Journal Articles

Alternating the Administration of Ixazomib and Lenalidomide As Maintenance Therapy after Autologous Transplant for Multiple Myeloma

Leona A Holmberg, Damian J. Green, Sarah S Lee, Andrew J Cowan
Journal: Blood
Blood (2022) 140 (Supplement 1): 10575–10576.
https://doi.org/10.1182/blood-2022-160265
Published: 2022
Journal Articles

Safety and Efficacy of Two Anakinra Dose Regimens for Refractory CRS or Icans after CAR T-Cell Therapy

Nicolas Gazeau, Pere Barba, Gloria Iacoboni, Mi Kwon, Rebeca Bailen, Juan Luis Reguera, Lucía López Corral, Rafael Hernani, Valentín Ortiz-Maldonado, Antonio Perez-Martinez, Richard T. Maziarz, Staci Williamson, Eneida R. Nemecek, Mazyar Shadman, Andrew Coman, Damian J. Green, Victor A. Chow, Alexandre V. Hirayama, David G. Maloney, Cameron J. Turtle, Jordan Gauthier
Journal: Blood
Blood (2021) 138 (Supplement 1): 2816.
https://doi.org/10.1182/blood-2021-147454
Published: 2021
Journal Articles

SEA-BCMA, an Investigational Nonfucosylated Monoclonal Antibody: Ongoing Results of a Phase 1 Study in Patients with Relapsed/Refractory Multiple Myeloma (SGNBCMA-001)

James E Hoffman, Brea Lipe, Jason Melear, Michaela Liedtke, Mark A. Schroeder, Ruben Niesvizky, Michael H. Tomasson, Christopher A. Yasenchak, Damian J. Green, Hong Li, Yinghui Wang, Phoenix Ho, Al-Ola Abdallah
Journal: Blood
Blood (2021) 138 (Supplement 1): 2740.
https://doi.org/10.1182/blood-2021-146047
Published: 2021
Journal Articles

Safety and Efficacy of Third Generation CD20 Targeted CAR-T (MB-106) for Treatment of Relapsed/Refractory B-NHL and CLL

Mazyar Shadman, Cecilia Yeung, Mary Redman, Sang Yun Lee, Dong Hoon Lee, Susan Ra, Chaitra S. Ujjani, Bruce J. Dezube, Christina Poh, Edus H. Warren, Aude G. Chapuis, Damian J. Green, Andrew J. Cowan, Ryan D. Cassaday, Hans-Peter Kiem, Jordan Gauthier, Cameron J. Turtle, Ryan C. Lynch, Stephen D. Smith, Ajay K Gopal, David G. Maloney, Brian G. Till
Journal: Blood
Blood (2021) 138 (Supplement 1): 3872.
https://doi.org/10.1182/blood-2021-149181
Published: 2021
Journal Articles

KarMMa-7, a Phase 1/2, Dose-Finding and Dose-Expansion Study of Combination Therapies with Idecabtagene Vicleucel (ide-cel, bb2121), a BCMA-Directed CAR T Cell Therapy for Relapsed/Refractory Multiple Myeloma (RRMM)

Noopur S. Raje, Jesús G. Berdeja, Paula Rodriguez-Otero, Damian J. Green, Sundar Jagannath, Sagar Lonial, Adrianna Gipson, Andrea Caia, Nathan Martin, Zhihong Yang, Gianfranco Pittari, Maria-Victoria Mateos
Journal: Blood
Blood (2021) 138 (Supplement 1): 4830.
https://doi.org/10.1182/blood-2021-147412
Published: 2021
Journal Articles

Safety and Efficacy of Fully Human BCMA CAR T Cells in Combination with a Gamma Secretase Inhibitor to Increase BCMA Surface Expression in Patients with Relapsed or Refractory Multiple Myeloma

Andrew J. Cowan, Margot Pont, Blythe Duke Sather, Cameron J. Turtle, Brian G. Till, Edward Libby, David G. Coffey, Sherilyn A. Tuazon, Brent L. Wood, Ted A Gooley, Qian Vicky Wu, Mazyar Shadman, Jordan Gauthier, Aude G. Chapuis, Filippo Milano, David G. Maloney, Stanley R. Riddell, Damian J. Green
Journal: Blood
Blood (2021) 138 (Supplement 1): 551.
https://doi.org/10.1182/blood-2021-154170
Published: 2021