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Blythe Duke Sather
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Journal Articles

Safety and Efficacy of Fully Human BCMA CAR T Cells in Combination with a Gamma Secretase Inhibitor to Increase BCMA Surface Expression in Patients with Relapsed or Refractory Multiple Myeloma

Andrew J. Cowan, Margot Pont, Blythe Duke Sather, Cameron J. Turtle, Brian G. Till, Edward Libby, David G. Coffey, Sherilyn A. Tuazon, Brent L. Wood, Ted A Gooley, Qian Vicky Wu, Mazyar Shadman, Jordan Gauthier, Aude G. Chapuis, Filippo Milano, David G. Maloney, Stanley R. Riddell, Damian J. Green
Journal: Blood
Blood (2021) 138 (Supplement 1): 551.
https://doi.org/10.1182/blood-2021-154170
Published: 2021
Journal Articles

Response to Bcma CAR-T Cells Correlates with Pretreatment Target Antigen Density and Is Improved By Small Molecule Inhibition of Gamma Secretase

Damian J. Green, MD, Margot Pont, PhD, Andrew J. Cowan, MD, Gabriel O Cole, Blythe Duke Sather, PhD, Anne M Nagengast, RN, Xaoling Song, Sushma Thomas, Brent L Wood, MD PhD, Michelle L Blake, PhD, Melissa G Works, PhD, Ted A Gooley, PhD, David G. Maloney, MD PhD, Stanley R. Riddell, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1856.
https://doi.org/10.1182/blood-2019-129582
Published: 2019
Journal Articles

Efficacy and Safety of Fully Human Bcma CAR T Cells in Combination with a Gamma Secretase Inhibitor to Increase Bcma Surface Expression in Patients with Relapsed or Refractory Multiple Myeloma

Andrew J. Cowan, MD, Margot Pont, PhD, Blythe Duke Sather, PhD, Cameron J. Turtle, MBBS, PhD, Brian G. Till, MD, Anne M Nagengast, RN, Edward N. Libby, III, MD, Pamela S. Becker, MD PhD, David G. Coffey, MD, Sherilyn A. Tuazon, MD, Brent L Wood, MD PhD, Michelle L Blake, PhD, Melissa G Works, PhD, Ted A Gooley, PhD, Qian Vicky Wu, PhD, David G. Maloney, MD PhD, Stanley R. Riddell, MD, Damian J. Green, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 204.
https://doi.org/10.1182/blood-2019-129405
Published: 2019
Journal Articles

Fully Human Bcma Targeted Chimeric Antigen Receptor T Cells Administered in a Defined Composition Demonstrate Potency at Low Doses in Advanced Stage High Risk Multiple Myeloma

Damian J. Green, MD, Margot Pont, PhD, Blythe Duke Sather, PhD, Andrew J. Cowan, MD, Cameron J. Turtle, MBBS, PhD, Brian G. Till, MD, Anne M Nagengast, RN, Edward N. Libby, III, MD, Pamela S. Becker, MD, David G. Coffey, MD, Sherilyn A. Tuazon, MD, Brent Wood, MD PhD, Michelle Blake, PhD, Melissa Works, PhD, Bruce S Thompson, PhD, Ted Gooley, PhD, Frederick R. Appelbaum, MD, David G. Maloney, MD PhD, Stanley R. Riddell, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1011.
https://doi.org/10.1182/blood-2018-99-117729
Published: 2018
Journal Articles

CAR T Cell Therapy Targeting G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D), a Novel Target for the Immunotherapy of Multiple Myeloma

Eric L. Smith, MD PhD, Kimberly Harrington, Mette Staehr, PhD, Reed Masakayan, MS, Jon Jones, BS, Thomas Long, PhD, Majid Ghoddusi, DVM, PhD, Terence J Purdon, MS, Trevor Do, Xiuyan Wang, PhD, Minh Pham, Jessica M Brown, Elizabeth Peguero, Carlos Fernández De Larrea, MD PhD, Pei Wang, PhD, Hong Liu, MD PhD, Yiyang Xu, PhD, Sarah Garrett, Steven Almo, PhD, Isabelle Riviere, PhD, Cheng Liu, PhD, Blythe Duke Sather, PhD, Renier J. Brentjens, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 589.
https://doi.org/10.1182/blood-2018-99-110471
Published: 2018
Journal Articles

Development of JCARH125: Optimization of a Fully Human Anti-Bcma CAR for Use in the Treatment of Multiple Myeloma

Kim Harrington, BS, Rebecca Wu, BS, Collin Hauskins, BS, Rupesh Amin, PhD, Thomas Long, PhD, Aye Chen, BA, Ayu Rahardjo, BS, Casey Thayer, BS, Garnet Navvaro, BS, Madelyn Myers, MS, Jon Jones, BS, Alex Baturevych, BS, Stan Morkowski, PhD, Ruth Salmon, PhD, Christopher J Bond, PhD, Mette Staehr, PhD, Terence J Purdon, MS, Reed Masakayan, MS, Cheng Liu, PhD, Hong Liu, MD PhD, Yiyang Xu, PhD, Pei Wang, PhD, Margot Pont, PhD, Damian J. Green, MD, Renier J. Brentjens, MD PhD, Eric L Smith, MDPhD, Blythe Duke Sather, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1813.
https://doi.org/10.1182/blood.V130.Suppl_1.1813.1813
Published: 2017
Journal Articles

Inhibiting TGFβ Signaling in CAR T-Cells May Significantly Enhance Efficacy of Tumor Immunotherapy

Queenie Vong, PhD, Chris Nye, MBT, Ron Hause, PhD, Chris Clouser, PhD, Jon Jones, BS, Stephen Burleigh, Christopher M Borges, PhD BS, Melissa Si Ying Chin, BS, Eugenio Marco, Luis Barrera, Jen Da Silva, Fred Harbinski, Georgia Giannoukos, Vidya Dhanapal, Yue Jiang, PhD, Ruth Salmon, PhD, Christopher J Wilson, PhD, Vic E Myer, PhD, Grant G Welstead, PhD, Christopher J Bond, PhD, Blythe Duke Sather, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1791.
https://doi.org/10.1182/blood.V130.Suppl_1.1791.1791
Published: 2017
Journal Articles

Lenalidomide Enhances Anti-BCMA Chimeric Antigen Receptor T Cell Function Against Multiple Myeloma

Melissa Works, PhD, Neha Soni, MS, Collin Hauskins, Catherine Sierra, BS, Alex Baturevych, BS, Jon Jones, BS, Wendy Curtis, BS, Timothy Johnstone, PhD, David Kugler, PhD, Yue Jiang, PhD, Ron Hause, PhD, Blythe Duke Sather, PhD, Ruth Salmon, PhD, Michael Ports, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1794.
https://doi.org/10.1182/blood.V130.Suppl_1.1794.1794
Published: 2017