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Journal Articles

Testing the Limits of Endogenous Thymic Regeneration after HCT Conditioning

Dante Dennis Acenas II, David Granadier, Lorenzo Iovino, Kirsten Cooper, Paul Deroos, Vanessa A Hernandez, Jarrod A Dudakov

Blood (2023) 142 (Supplement 1): 3427.

https://doi.org/10.1182/blood-2023-190235

Published: 2023

Journal Articles

Day +3/Day 0 Ferritin Ratio: A Simple Point-of-Care Index Predictive of Severe Immune Effector Cell-Associated Neurotoxicity Syndrome after CD19 CAR T-Cell Therapy

Blood (2023) 142 (Supplement 1): 3495.

https://doi.org/10.1182/blood-2023-182597

Published: 2023

Journal Articles

Machine Learning-Based Time-Series Clustering Identifies Archetypal Trajectories of Hematotoxicity after CAR T-Cell Therapy

Blood (2023) 142 (Supplement 1): 2143.

https://doi.org/10.1182/blood-2023-174106

Published: 2023

Journal Articles

Hematopoietic Stem Cell Transplantation (HCT) Conditioning Leads to NK Cell Cytotoxicity Limiting Endogenous Thymus Regeneration

David Granadier, Kirsten Cooper, Dante Dennis Acenas II, Lorenzo Iovino, Paul Deroos, Vanessa A Hernandez, Jarrod A Dudakov

Blood (2023) 142 (Supplement 1): 461.

https://doi.org/10.1182/blood-2023-188387

Published: 2023

Journal Articles

Factors Associated with Prolonged CRS and Neurotoxicity after Treatment with Axicabtagene Ciloleucel

Aya Albittar, Jenna M Voutsinas, Andrew J Portuguese, Jennifer J. Huang, Emily C Liang, Qian Wu, Xinyi Fan, Alexandre V Hirayama, Erik L Kimble, Lorenzo Iovino, Christina Poh, Ajay K Gopal, Mazyar Shadman, Brian G Till, Filippo Milano, Aude G Chapuis, Ryan D Cassaday, David G Maloney, Jordan Gauthier

Blood (2023) 142 (Supplement 1): 2126.

https://doi.org/10.1182/blood-2023-180128

Published: 2023

Journal Articles

Lisocabtagene Maraleucel Versus Axicabtagene Ciloleucel: Efficacy and Toxicity in a Real-World Setting

Andrew J Portuguese, Aya Albittar, Emily C Liang, Jennifer J. Huang, Alexandre V Hirayama, Erik L Kimble, Lorenzo Iovino, Christina Poh, Ajay K Gopal, Mazyar Shadman, Brian G Till, Hans-Peter Kiem, Filippo Milano, Aude G Chapuis, Folashade Otegbeye, Ryan D Cassaday, David G Maloney, Jordan Gauthier

Blood (2023) 142 (Supplement 1): 2131.

https://doi.org/10.1182/blood-2023-172978

Published: 2023

Journal Articles

Impact of “Cell-of-Origin” on Outcome after Axicabtagene-Ciloleucel CAR-T Cell Therapy in Relapsed/Refractory Aggressive Non-Hodgkin B-Cell Lymphomas

Ilaria Romano, Jordan Gauthier, Ryan C Lynch, Ajay K Gopal, Alexandre V Hirayama, Kikkeri N Naresh, Alireza Torabi, Stephen D Smith, Brian G Till, David G Maloney, Chaitra S Ujjani, Christina Poh, Filippo Milano, Aude G Chapuis, Mazyar Shadman, Lorenzo Iovino

Blood (2023) 142 (Supplement 1): 2137.

https://doi.org/10.1182/blood-2023-181956

Published: 2023

Journal Articles

Zinc Status Affects T Cell Reconstitution in Patients Receiving Naïve T Cell Depleted Allogeneic HSCT

Lorenzo Iovino, Jessica Lok, Jacqueline Diaz, Heather Persinger, Vanessa A Hernandez, Kirsten Cooper, Paul Deroos, David Granadier, Dante Dennis Acenas II, Jarrod A Dudakov, Marie Bleakley

Blood (2023) 142 (Supplement 1): 3562.

https://doi.org/10.1182/blood-2023-182370

Published: 2023

Journal Articles

Phase 2 Study of Anakinra to Prevent CRS and Neurotoxicity after Treatment with Lisocabtagene Maraleucel: Planned Interim Analysis

Blood (2023) 142 (Supplement 1): 6848.

https://doi.org/10.1182/blood-2023-172695

Published: 2023

Journal Articles

Phase 2 Study of CD19 CAR T Cells with a Fully Human Binder for Large B-Cell Lymphoma in Relapse or Progression after a Murine Binder-Bearing CD19 CAR T-Cell Therapy

Blood (2023) 142 (Supplement 1): 6860.

https://doi.org/10.1182/blood-2023-181273

Published: 2023

Journal Articles

Interleukin 18 Suppresses Regeneration of the Thymus

David Granadier, Kirsten Cooper, Sinéad Kinsella, Cindy Evandy, Lorenzo Iovino, Paul DeRoos, Steve Shannon-Sevillano, Dante Denny Acenas, Jarrod A Dudakov

Blood (2022) 140 (Supplement 1): 1169–1170.

https://doi.org/10.1182/blood-2022-168432

Published: 2022

Journal Articles

The Zinc-Sensing Receptor GPR39 Is a Master Regulator of Immune Reconstitution after Bone Marrow Transplant in the Thymus and in the Bone Marrow

Lorenzo Iovino, Kirsten Cooper, Paul DeRoos, Cindy Evandy, David Granadier, Sinéad Kinsella, Dante Denny Acenas, Jarrod A Dudakov

Blood (2022) 140 (Supplement 1): 10206–10207.

https://doi.org/10.1182/blood-2022-162572

Published: 2022

Journal Articles

Activation of the zinc-sensing receptor GPR39 promotes T-cell reconstitution after hematopoietic cell transplant in mice

Lorenzo Iovino, Kirsten Cooper, Paul deRoos, Sinéad Kinsella, Cindy Evandy, Tamas Ugrai, Francesco Mazziotta, Kathleen S. Ensbey, David Granadier, Kayla Hopwo, Colton Smith, Alex Gagnon, Sara Galimberti, Mario Petrini, Geoffrey R. Hill, Jarrod A. Dudakov

Blood (2022) 139 (25): 3655–3666.

https://doi.org/10.1182/blood.2021013950

Published: 2022

Includes: Supplemental data

Journal Articles

Damage-Induced Pyroptotic Cell Death Facilitates Regeneration of the Thymus

Sinéad Kinsella, MSc,PhD, Cindy Evandy, Kayla S Hopwo, Kirsten Cooper, Lorenzo Iovino, MD, Colton W Smith, Reema Jain, PhD, Paul DeRoos, Jarrod A Dudakov, PhD

Blood (2020) 136 (Supplement 1): 28.

https://doi.org/10.1182/blood-2020-143051

Published: 2020

Journal Articles

The Impact of Different Mobilization Strategies in the Setting of Multiple Myeloma

Francesco Mazziotta, MD, Gabriele Buda, MD PhD, Nadia Cecconi, MD, Giulia Cervetti, MD, Lorenzo Iovino, MD, Enrico Orciuolo, MD PhD, Matteo Pelosini, MD PhD, Edoardo Benedetti, MD, Francesco Caracciolo, MD, Giovanni Carulli, MD, Sara Galimberti, MD PhD, Mario Petrini, MD PhD

Blood (2019) 134 (Supplement_1): 3254.

https://doi.org/10.1182/blood-2019-126118

Published: 2019

Journal Articles

Homeostatic Regulation of Apoptosis Governs Thymus Regeneration

Sinéad Kinsella, MSc,PhD, Kirsten Cooper, Lorenzo Iovino, MD, Paul DeRoos, Reema Jain, PhD, Jarrod A Dudakov, PhD

Blood (2019) 134 (Supplement_1): 587.

https://doi.org/10.1182/blood-2019-131513

Published: 2019

Journal Articles

Zinc Treatment Stimulates Thymic Regeneration after Bone Marrow Transplant

Lorenzo Iovino, MD, Sinéad Kinsella, MSc,PhD, Kirsten Cooper, Reema Jain, PhD, Paul DeRoos, Alex Gagnon, Tamas M Ugrai, Gabriele Buda, MD PhD, Sara Galimberti, MD PhD, Mario Petrini, MD PhD, Jarrod A Dudakov, PhD

Blood (2019) 134 (Supplement_1): 4422.

https://doi.org/10.1182/blood-2019-129290

Published: 2019

Journal Articles

NOD2 Acts As a Master Regulator of Endogenous Thymic Regeneration

Sinéad Kinsella, MSc,PhD, Kirsten Cooper, Paul DeRoos, Reema Jain, PhD, Lorenzo Iovino, MD, Jarrod A Dudakov, PhD

Blood (2018) 132 (Supplement 1): 478.

https://doi.org/10.1182/blood-2018-99-115386

Published: 2018

Journal Articles

Zinc Supplementation Improves T Cell Reconstitution after Allogeneic HSCT By Stimulating Endogenous Pathways of Thymic Regeneration

Lorenzo Iovino, MD, Kirsten Cooper, Sinéad Kinsella, MSc, PhD, Paul DeRoos, Reema Jain, PhD, Sara Galimberti, Enrico Orciuolo, PhD MD, Edoardo Benedetti, MD, Mario Petrini, PhD MD Prof, Jarrod A Dudakov, PhD

Blood (2018) 132 (Supplement 1): 3321.

https://doi.org/10.1182/blood-2018-99-112707

Published: 2018

Journal Articles

Cytokine Release from Stimulated PBMC after-HSCT: Results of a Post-Transplant Zinc Oral Supplementation Trial (ZENITH)

Lorenzo Iovino, MD, Federico Pratesi, BD, Francesco Mazziotta, MD, Enrico Orciuolo, PhD MD, Gabriele Buda, PhD MD, Edoardo Benedetti, MD, Mario Petrini, PhD MD Prof, Paola Migliorini, PhD MD Prof, Sara Galimberti, PhD MD

Blood (2017) 130 (Supplement 1): 1017.

https://doi.org/10.1182/blood.V130.Suppl_1.1017.1017

Published: 2017

NARROW

Testing the Limits of Endogenous Thymic Regeneration after HCT Conditioning

Day +3/Day 0 Ferritin Ratio: A Simple Point-of-Care Index Predictive of Severe Immune Effector Cell-Associated Neurotoxicity Syndrome after CD19 CAR T-Cell Therapy

Machine Learning-Based Time-Series Clustering Identifies Archetypal Trajectories of Hematotoxicity after CAR T-Cell Therapy

Hematopoietic Stem Cell Transplantation (HCT) Conditioning Leads to NK Cell Cytotoxicity Limiting Endogenous Thymus Regeneration

Factors Associated with Prolonged CRS and Neurotoxicity after Treatment with Axicabtagene Ciloleucel

Lisocabtagene Maraleucel Versus Axicabtagene Ciloleucel: Efficacy and Toxicity in a Real-World Setting

Impact of “Cell-of-Origin” on Outcome after Axicabtagene-Ciloleucel CAR-T Cell Therapy in Relapsed/Refractory Aggressive Non-Hodgkin B-Cell Lymphomas

Zinc Status Affects T Cell Reconstitution in Patients Receiving Naïve T Cell Depleted Allogeneic HSCT

Phase 2 Study of Anakinra to Prevent CRS and Neurotoxicity after Treatment with Lisocabtagene Maraleucel: Planned Interim Analysis

Phase 2 Study of CD19 CAR T Cells with a Fully Human Binder for Large B-Cell Lymphoma in Relapse or Progression after a Murine Binder-Bearing CD19 CAR T-Cell Therapy

Interleukin 18 Suppresses Regeneration of the Thymus

The Zinc-Sensing Receptor GPR39 Is a Master Regulator of Immune Reconstitution after Bone Marrow Transplant in the Thymus and in the Bone Marrow

Activation of the zinc-sensing receptor GPR39 promotes T-cell reconstitution after hematopoietic cell transplant in mice

Damage-Induced Pyroptotic Cell Death Facilitates Regeneration of the Thymus

The Impact of Different Mobilization Strategies in the Setting of Multiple Myeloma

Homeostatic Regulation of Apoptosis Governs Thymus Regeneration

Zinc Treatment Stimulates Thymic Regeneration after Bone Marrow Transplant

NOD2 Acts As a Master Regulator of Endogenous Thymic Regeneration

Zinc Supplementation Improves T Cell Reconstitution after Allogeneic HSCT By Stimulating Endogenous Pathways of Thymic Regeneration

Cytokine Release from Stimulated PBMC after-HSCT: Results of a Post-Transplant Zinc Oral Supplementation Trial (ZENITH)

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American Society of Hematology

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American Society of Hematology

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