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Melissa L. Comstock
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Journal Articles

Single-cell analysis of the multiple myeloma microenvironment after gamma-secretase inhibition and CAR T-cell therapy

David G Coffey, Pinar Ataca Atilla, Erden Atilla, Ola Landgren, Andrew J Cowan, Sylvain Simon, Margot Pont, Melissa L. Comstock, Geoffrey R Hill, Stanley R. Riddell, Damian J Green
Journal: Blood
Blood blood.2024025231.
https://doi.org/10.1182/blood.2024025231
Published: 2024
Includes: Supplemental data
Journal Articles

Regulatory T cells suppress myeloma-specific immunity during autologous stem cell mobilization and transplantation

Shuichiro Takahashi, Simone A. Minnie, Kathleen S. Ensbey, Christine R. Schmidt, Tomoko Sekiguchi, Samuel R. W. Legg, Ping Zhang, Motoko Koyama, Stuart D. Olver, Alika D. Collinge, Sara Keshmiri, Melissa L. Comstock, Antiopi Varelias, Damian J. Green, Geoffrey R. Hill
Journal: Blood
Blood (2024) 143 (16): 1656–1669.
https://doi.org/10.1182/blood.2023022000
Published: 2024
Includes: Supplemental data
Journal Articles

Resistance to CD38 Antigen Targeted Therapy in Multiple Myeloma May Result from Underrecognized Chromosome 4 Gene Deletions

Andrew J Portuguese, Min Fang, Sherilyn A. Tuazon, Margot Pont, Xiaoyu Qu, Carolyn Shasha, Melissa L Comstock, Justina Lyons, Gabriel Cole, Evan W. Newell, Emily Glynn, Lorinda Soma, Damian J Green
Journal: Blood
Blood (2023) 142 (Supplement 1): 1976.
https://doi.org/10.1182/blood-2023-186688
Published: 2023
Journal Articles

Trogocytosis May Attenuate the Efficacy of Anti-BCMA CAR T Cells Administered in Combination with γ-Secretase Inhibitor

Pinar Ataca Atilla, Sylvain Simon, Erden Atilla, Melissa L Comstock, Andrew J. Cowan, Geoffrey R Hill, Stanley R. Riddell, Damian J Green
Journal: Blood
Blood (2023) 142 (Supplement 1): 2083.
https://doi.org/10.1182/blood-2023-187132
Published: 2023
Journal Articles

Impact of Gamma-Secretase Inhibition on the Multiple Myeloma Immune Microenvironment

David Coffey, Ola Landgren, Andrew J. Cowan, Pinar Ataca Atilla, Sylvain Simon, Margot Pont, Melissa L Comstock, Geoffrey R Hill, Stanley R. Riddell, Damian J Green
Journal: Blood
Blood (2023) 142 (Supplement 1): 4683.
https://doi.org/10.1182/blood-2023-186980
Published: 2023
Journal Articles

BCMA-Directed Low Dose Alpha-Emitter Therapy Eliminates Minimal Residual Disease in a Multiple Myeloma Mouse Xenograft Model

Melissa L Comstock, Shyril O'Steen, Yukang Lin, Donald Hamlin, D Scott Wilbur, Johnnie J. Orozco, Rainer F. Storb, Roland B. Walter, Pinar Ataca Atilla, Brian G Till, Geoffrey R Hill, Brenda M. Sandmaier, Damian J Green
Journal: Blood
Blood (2023) 142 (Supplement 1): 53.
https://doi.org/10.1182/blood-2023-188055
Published: 2023
Journal Articles

γ-Secretase inhibition increases efficacy of BCMA-specific chimeric antigen receptor T cells in multiple myeloma

Margot J. Pont, Tyler Hill, Gabriel O. Cole, Joe J. Abbott, Jessica Kelliher, Alexander I. Salter, Michael Hudecek, Melissa L. Comstock, Anusha Rajan, Bharvin K. R. Patel, Jenna M. Voutsinas, Qian Wu, Lingfeng Liu, Andrew J. Cowan, Brent L. Wood, Damian J. Green, Stanley R. Riddell
Journal: Blood
Blood (2019) 134 (19): 1585–1597.
https://doi.org/10.1182/blood.2019000050
Published: 2019
Includes: Supplemental data
Journal Articles

The α-emitter astatine-211 targeted to CD38 can eradicate multiple myeloma in a disseminated disease model

Shyril O’Steen, Melissa L. Comstock, Johnnie J. Orozco, Donald K. Hamlin, D. Scott Wilbur, Jon C. Jones, Aimee Kenoyer, Margaret E. Nartea, Yukang Lin, Brian W. Miller, Theodore A. Gooley, Sherilyn A. Tuazon, Brian G. Till, Ajay K. Gopal, Brenda M. Sandmaier, Oliver W. Press, Damian J. Green
Journal: Blood
Blood (2019) 134 (15): 1247–1256.
https://doi.org/10.1182/blood.2019001250
Published: 2019
Includes: Supplemental data
Journal Articles

CD38-bispecific antibody pretargeted radioimmunotherapy for multiple myeloma and other B-cell malignancies

Damian J. Green, Shyril O’Steen, Yukang Lin, Melissa L. Comstock, Aimee L. Kenoyer, Donald K. Hamlin, D. Scott Wilbur, Darrell R. Fisher, Margaret Nartea, Mark D. Hylarides, Ajay K. Gopal, Theodore A. Gooley, Johnnie J. Orozco, Brian G. Till, Kelly D. Orcutt, K. Dane Wittrup, Oliver W. Press
Journal: Blood
Blood (2018) 131 (6): 611–620.
https://doi.org/10.1182/blood-2017-09-807610
Published: 2018
Includes: Supplemental data