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Journal Articles

4D intravital imaging studies identify platelets as the predominant cellular procoagulant surface in a mouse hemostasis model

Abigail Ballard-Kordeliski, Robert H. Lee, Ellen C. O’Shaughnessy, Paul Y. Kim, Summer R. Jones, Rafal Pawlinski, Matthew J. Flick, David S. Paul, Nigel Mackman, David A. Adalsteinsson, Wolfgang Bergmeier

Blood (2024) 144 (10): 1116–1126.

https://doi.org/10.1182/blood.2023022608

Published: 2024

Includes: Multimedia, Supplemental data

Journal Articles

Mice expressing nonpolymerizable fibrinogen have reduced arterial and venous thrombosis with preserved hemostasis

Woosuk S. Hur, Tomohiro Kawano, Jean Marie N. Mwiza, David S. Paul, Robert H. Lee, Emily G. Clark, Emma G. Bouck, Ananya Dutta, Can Cai, Stephen R. Baker, Martin Guthold, Nigel Mackman, Pierre Mangin, Alisa S. Wolberg, Wolfgang Bergmeier, Matthew J. Flick

Blood (2024) 143 (2): 105–117.

https://doi.org/10.1182/blood.2023020805

Published: 2024

Includes: Multimedia, Supplemental data

Journal Articles

4D Intravital Imaging Studies Identify Platelets As the Predominant Cellular Procoagulant Surface in Hemostasis

Abigail Ballard, Wolfgang Bergmeier, David Paul, Robert Hugh Lee, Nigel Mackman, Matthew J. Flick, Ellen O'Shaughnessy, David Adalsteinsson, Paul Kim

Blood (2023) 142 (Supplement 1): 2572.

https://doi.org/10.1182/blood-2023-179274

Published: 2023

Journal Articles

Thrombocytopenia in a Mouse Model of Pancreatic Cancer

Michelle M. Luo, Yaqiu Sang, Maria N. Barrachina, Andrew P. Stone, Keely G. Davey, Yi Yang, Lori A. Holle, Tomohiro Kawano, Nigel Mackman, Matthew J. Flick, Kellie R. Machlus, Alisa S. Wolberg

Blood (2022) 140 (Supplement 1): 8384.

https://doi.org/10.1182/blood-2022-169771

Published: 2022

Journal Articles

Pancreatic Ductal Adenocarcinoma Causes Bleeding Phenotype in Mice Associated with Loss of Procoagulant Activity and Increased Thrombomodulin Sensitivity

Michelle M. Luo, Keely G. Davey, Yohei Hisada, Yi Yang, Lori A. Holle, Ananya Dutta, Brian C. Cooley, Nigel Mackman, Matthew J. Flick, Alisa S. Wolberg

Blood (2022) 140 (Supplement 1): 11278.

https://doi.org/10.1182/blood-2022-169582

Published: 2022

Journal Articles

Hypofibrinogenemia with preserved hemostasis and protection from thrombosis in mice with an Fga truncation mutation

Woosuk S. Hur, David S. Paul, Emma G. Bouck, Oscar A. Negrón, Jean-Marie Mwiza, Lauren G. Poole, Holly M. Cline-Fedewa, Emily G. Clark, Lih Jiin Juang, Jerry Leung, Christian J. Kastrup, Tatiana P. Ugarova, Alisa S. Wolberg, James P. Luyendyk, Wolfgang Bergmeier, Matthew J. Flick

Blood (2022) 139 (9): 1374–1388.

https://doi.org/10.1182/blood.2021012537

Published: 2022

Includes: Multimedia, Supplemental data

Journal Articles

Suppression of fibrin(ogen)-driven pathologies in disease models through controlled knockdown by lipid nanoparticle delivery of siRNA

Lih Jiin Juang, Woosuk S. Hur, Lakmali M. Silva, Amy W. Strilchuk, Brenton Francisco, Jerry Leung, Madelaine K. Robertson, Dafna J. Groeneveld, Bridget La Prairie, Elizabeth M. Chun, Andrew P. Cap, James P. Luyendyk, Joseph S. Palumbo, Pieter R. Cullis, Thomas H. Bugge, Matthew J. Flick, Christian J. Kastrup

Blood (2022) 139 (9): 1302–1311.

https://doi.org/10.1182/blood.2021014559

Published: 2022

Journal Articles

Targeting neutrophil PKM2 for stroke treatment

Matthew J. Flick

Blood (2022) 139 (8): 1131–1132.

https://doi.org/10.1182/blood.2021014199

Published: 2022

Journal Articles

Fibrin(ogen) Promotes Immune Cell Infiltration, Dysbiosis and ROS Production in Experimental Colitis

Balkrishan Sharma, Ramesh Kudira, Leah A. Rosenfeldt, Benjamin E Gourley, Rachel Cantrell, Miki Watanabe, Olivia Edwards, Lindsey E Romick-Rosendale, David Haslam, Matthew J. Flick, Joseph S. Palumbo

Blood (2021) 138 (Supplement 1): 443.

https://doi.org/10.1182/blood-2021-153148

Published: 2021

Journal Articles

Protective Role of Plasminogen Deficiency in Non-Alcoholic Fatty Liver Disease and Glucose Dysmetabolism

Woosuk Steve Steve Hur, Y-Van Nyugen, Matthew J. Flick

Blood (2021) 138 (Supplement 1): 1026.

https://doi.org/10.1182/blood-2021-145352

Published: 2021

Journal Articles

Plasmin-mediated cleavage of high-molecular-weight kininogen contributes to acetaminophen-induced acute liver failure

Michael W. Henderson, Erica M. Sparkenbaugh, Shaobin Wang, Anton Ilich, Denis F. Noubouossie, Reiner Mailer, Thomas Renné, Matthew J. Flick, James P. Luyendyk, Zu-Lin Chen, Sidney Strickland, R. Todd Stravitz, Keith R. McCrae, Nigel S. Key, Rafal Pawlinski

Blood (2021) 138 (3): 259–272.

https://doi.org/10.1182/blood.2020006198

Published: 2021

Includes: Supplemental data

Journal Articles

Mechanism of ICH with tPA thrombolysis

Matthew J. Flick

Blood (2021) 138 (1): 8–9.

https://doi.org/10.1182/blood.2021011268

Published: 2021

Journal Articles

Factor XIII cross-links fibrin(ogen) independent of fibrin polymerization in experimental acute liver injury

Lauren G. Poole, Anna K. Kopec, Dafna J. Groeneveld, Asmita Pant, Kevin S. Baker, Holly M. Cline-Fedewa, Matthew J. Flick, James P. Luyendyk

Blood (2021) 137 (18): 2520–2531.

https://doi.org/10.1182/blood.2020007415

Published: 2021

Includes: Supplemental data

Journal Articles

A high-fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice

Adam Miszta, Anna K. Kopec, Asmita Pant, Lori A. Holle, James R. Byrnes, Daniel A. Lawrence, Kirk C. Hansen, Matthew J. Flick, James P. Luyendyk, Bas de Laat, Alisa S. Wolberg

Blood (2020) 135 (19): 1704–1717.

https://doi.org/10.1182/blood.2019004267

Published: 2020

Includes: Supplemental data

Journal Articles

Fibrinogen Activates FAK to Promote the Colorectal Adenocarcinoma Growth

Balkrishan Sharma, PhD, Duaa Mureb, BS, Sumit Murab, PhD, Leah A. Rosenfeldt, BS, Brenton J Francisco, MD, Alexander A Boucher, MD, Rachel Cantrell, BS, Jacob Mast, Matthew J. Flick, PhD, Patrick W Whitlock, MD, Joseph S. Palumbo, MD

Blood (2019) 134 (Supplement_1): 1111.

https://doi.org/10.1182/blood-2019-130497

Published: 2019

Journal Articles

Plasmin-mediated fibrinolysis enables macrophage migration in a murine model of inflammation

Lakmali Munasinghage Silva, Andrew Gary Lum, Collin Tran, Molly W. Shaw, Zhen Gao, Matthew J. Flick, Niki M. Moutsopoulos, Thomas H. Bugge, Eric S. Mullins

Blood (2019) 134 (3): 291–303.

https://doi.org/10.1182/blood.2018874859

Published: 2019

Includes: Supplemental data

Journal Articles

The multifaceted role of fibrinogen in tissue injury and inflammation

James P. Luyendyk, Jonathan G. Schoenecker, Matthew J. Flick

Blood (2019) 133 (6): 511–520.

https://doi.org/10.1182/blood-2018-07-818211

Published: 2019

Journal Articles

A Human Fibrinogen Variant with Impaired Staphylococcus Aureus Binding Function Promotes Host Survival during Septicemia in Mice

Oscar Negron, Jaap Koopman, PhD, Miranda Weggeman, PhD, Linda Huisman, PhD, Amanda Stang, Matthew J. Flick, PhD

Blood (2018) 132 (Supplement 1): 3775.

https://doi.org/10.1182/blood-2018-99-118491

Published: 2018

Journal Articles

Diminished Renal Pathology in a Mouse Model of Sickle Cell Anemia in Which Fibrinogen Binding to Mac-1 Is Inhibited

Md Nasimuzzaman, PhD, Paritha I. Arumugam, PhD, Eric S. Mullins, MD, Jeanne M James, MD, Katherine VandenHeuvel, MD, Marilou Narciso, BS, Maureen A. Shaw, MSc, Sarah McGraw, Bruce J. Aronow, PhD, Matthew J. Flick, PhD, Punam Malik, MD

Blood (2018) 132 (Supplement 1): 267.

https://doi.org/10.1182/blood-2018-99-112641

Published: 2018

Journal Articles

Plasmin-Mediated Fibrinolysis Enables Macrophage Migration Via Liberation from Fibrin-α M β 2 Interactions

Eric S. Mullins, MD, Maureen A. Shaw, MSc, Zhen Gao, PhD, Matthew J. Flick, PhD

Blood (2018) 132 (Supplement 1): 136.

https://doi.org/10.1182/blood-2018-99-117018

Published: 2018

NARROW

4D intravital imaging studies identify platelets as the predominant cellular procoagulant surface in a mouse hemostasis model

Mice expressing nonpolymerizable fibrinogen have reduced arterial and venous thrombosis with preserved hemostasis

4D Intravital Imaging Studies Identify Platelets As the Predominant Cellular Procoagulant Surface in Hemostasis

Thrombocytopenia in a Mouse Model of Pancreatic Cancer

Pancreatic Ductal Adenocarcinoma Causes Bleeding Phenotype in Mice Associated with Loss of Procoagulant Activity and Increased Thrombomodulin Sensitivity

Hypofibrinogenemia with preserved hemostasis and protection from thrombosis in mice with an Fga truncation mutation

Suppression of fibrin(ogen)-driven pathologies in disease models through controlled knockdown by lipid nanoparticle delivery of siRNA

Targeting neutrophil PKM2 for stroke treatment

Fibrin(ogen) Promotes Immune Cell Infiltration, Dysbiosis and ROS Production in Experimental Colitis

Protective Role of Plasminogen Deficiency in Non-Alcoholic Fatty Liver Disease and Glucose Dysmetabolism

Plasmin-mediated cleavage of high-molecular-weight kininogen contributes to acetaminophen-induced acute liver failure

Mechanism of ICH with tPA thrombolysis

Factor XIII cross-links fibrin(ogen) independent of fibrin polymerization in experimental acute liver injury

A high-fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice

Fibrinogen Activates FAK to Promote the Colorectal Adenocarcinoma Growth

Plasmin-mediated fibrinolysis enables macrophage migration in a murine model of inflammation

The multifaceted role of fibrinogen in tissue injury and inflammation

A Human Fibrinogen Variant with Impaired Staphylococcus Aureus Binding Function Promotes Host Survival during Septicemia in Mice

Diminished Renal Pathology in a Mouse Model of Sickle Cell Anemia in Which Fibrinogen Binding to Mac-1 Is Inhibited

Plasmin-Mediated Fibrinolysis Enables Macrophage Migration Via Liberation from Fibrin-α M β 2 Interactions

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American Society of Hematology

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American Society of Hematology

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