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Journal Articles

Reciprocal stabilization of coagulation factor XIII-A and -B subunits is a determinant of plasma FXIII concentration

James R. Byrnes, Taek Lee, Sherif Sharaby, Robert A. Campbell, Dre’Von A. Dobson, Lori A. Holle, Michelle Luo, Kadri Kangro, Jonathon W. Homeister, Maria M. Aleman, James P. Luyendyk, Bryce A. Kerlin, Julie B. Dumond, Alisa S. Wolberg

Blood (2024) 143 (5): 444–455.

https://doi.org/10.1182/blood.2023022042

Published: 2024

Includes: Supplemental data

Journal Articles

Hypofibrinogenemia with preserved hemostasis and protection from thrombosis in mice with an Fga truncation mutation

Woosuk S. Hur, David S. Paul, Emma G. Bouck, Oscar A. Negrón, Jean-Marie Mwiza, Lauren G. Poole, Holly M. Cline-Fedewa, Emily G. Clark, Lih Jiin Juang, Jerry Leung, Christian J. Kastrup, Tatiana P. Ugarova, Alisa S. Wolberg, James P. Luyendyk, Wolfgang Bergmeier, Matthew J. Flick

Blood (2022) 139 (9): 1374–1388.

https://doi.org/10.1182/blood.2021012537

Published: 2022

Includes: Multimedia, Supplemental data

Journal Articles

Suppression of fibrin(ogen)-driven pathologies in disease models through controlled knockdown by lipid nanoparticle delivery of siRNA

Lih Jiin Juang, Woosuk S. Hur, Lakmali M. Silva, Amy W. Strilchuk, Brenton Francisco, Jerry Leung, Madelaine K. Robertson, Dafna J. Groeneveld, Bridget La Prairie, Elizabeth M. Chun, Andrew P. Cap, James P. Luyendyk, Joseph S. Palumbo, Pieter R. Cullis, Thomas H. Bugge, Matthew J. Flick, Christian J. Kastrup

Blood (2022) 139 (9): 1302–1311.

https://doi.org/10.1182/blood.2021014559

Published: 2022

Journal Articles

Manipulation of Fatty Acid Metabolism Impairs Megakaryocyte Differentiation and Platelet Production

Maria N. Barrachina, Gerard Pernes, Isabelle C Becker, Dafna Groeneveld, James P. Luyendyk, Peter J Meikle, Graeme I Lancaster, Andrew J Murphy, Kellie Machlus

Blood (2021) 138 (Supplement 1): 577.

https://doi.org/10.1182/blood-2021-151316

Published: 2021

Journal Articles

Plasmin-mediated cleavage of high-molecular-weight kininogen contributes to acetaminophen-induced acute liver failure

Michael W. Henderson, Erica M. Sparkenbaugh, Shaobin Wang, Anton Ilich, Denis F. Noubouossie, Reiner Mailer, Thomas Renné, Matthew J. Flick, James P. Luyendyk, Zu-Lin Chen, Sidney Strickland, R. Todd Stravitz, Keith R. McCrae, Nigel S. Key, Rafal Pawlinski

Blood (2021) 138 (3): 259–272.

https://doi.org/10.1182/blood.2020006198

Published: 2021

Includes: Supplemental data

Journal Articles

Factor XIII cross-links fibrin(ogen) independent of fibrin polymerization in experimental acute liver injury

Lauren G. Poole, Anna K. Kopec, Dafna J. Groeneveld, Asmita Pant, Kevin S. Baker, Holly M. Cline-Fedewa, Matthew J. Flick, James P. Luyendyk

Blood (2021) 137 (18): 2520–2531.

https://doi.org/10.1182/blood.2020007415

Published: 2021

Includes: Supplemental data

Journal Articles

A high-fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice

Adam Miszta, Anna K. Kopec, Asmita Pant, Lori A. Holle, James R. Byrnes, Daniel A. Lawrence, Kirk C. Hansen, Matthew J. Flick, James P. Luyendyk, Bas de Laat, Alisa S. Wolberg

Blood (2020) 135 (19): 1704–1717.

https://doi.org/10.1182/blood.2019004267

Published: 2020

Includes: Supplemental data

Journal Articles

Intrahepatic fibrin(ogen) deposition drives liver regeneration after partial hepatectomy in mice and humans

Dafna Groeneveld, David Pereyra, Zwanida Veldhuis, Jelle Adelmeijer, Petra Ottens, Anna K. Kopec, Patrick Starlinger, Ton Lisman, James P. Luyendyk

Blood (2019) 133 (11): 1245–1256.

https://doi.org/10.1182/blood-2018-08-869057

Published: 2019

Includes: Supplemental data

Journal Articles

The multifaceted role of fibrinogen in tissue injury and inflammation

James P. Luyendyk, Jonathan G. Schoenecker, Matthew J. Flick

Blood (2019) 133 (6): 511–520.

https://doi.org/10.1182/blood-2018-07-818211

Published: 2019

Journal Articles

Inflammation and Tissue Damage Mediated By PAR-1 Expression Is Cell Type-Specific and Varies Depending on the Inflammatory Challenge

Alexander A Boucher, MD, Leah A. Rosenfeldt, BS, Duaa Mureb, BS, Anna K Kopec, PhD, James P. Luyendyk, PhD, Matthew J. Flick, PhD, Joseph S. Palumbo, MD

Blood (2018) 132 (Supplement 1): 133.

https://doi.org/10.1182/blood-2018-99-117312

Published: 2018

Journal Articles

Fibrin deposition following bile duct injury limits fibrosis through an α M β 2 -dependent mechanism

Nikita Joshi, Anna K. Kopec, Jessica L. Ray, Holly Cline-Fedewa, Atta Nawabi, Timothy Schmitt, Rance Nault, Timothy R. Zacharewski, Cheryl E. Rockwell, Matthew J. Flick, James P. Luyendyk

Blood (2016) 127 (22): 2751–2762.

https://doi.org/10.1182/blood-2015-09-670703

Published: 2016

Includes: Supplemental data

Journal Articles

Tumor Cell Thrombin/PAR-1 Signaling Drives Pancreatic Ductal Adenocarcinoma Growth and Dissemination

Matthew J. Flick, PhD, Cheryl Rewerts, M.S., Carolina Cruz, Joseph S. Palumbo, MD, James P. Luyendyk, PhD, Yi Yang, Stephen F. Konieczny, PhD

Blood (2015) 126 (23): 1070.

https://doi.org/10.1182/blood.V126.23.1070.1070

Published: 2015

Journal Articles

Platelets and protease-activated receptor-4 contribute to acetaminophen-induced liver injury in mice

Kazuhisa Miyakawa, Nikita Joshi, Bradley P. Sullivan, Ryan Albee, Christina Brandenberger, Hartmut Jaeschke, Mitchell R. McGill, Michael A. Scott, Patricia E. Ganey, James P. Luyendyk, Robert A. Roth

Blood (2015) 126 (15): 1835–1843.

https://doi.org/10.1182/blood-2014-09-598656

Published: 2015

Includes: Supplemental data

Journal Articles

A balance between TFPI and thrombin-mediated platelet activation is required for murine embryonic development

Paul E. R. Ellery, Susan A. Maroney, Brian C. Cooley, James P. Luyendyk, Mark Zogg, Hartmut Weiler, Alan E. Mast

Blood (2015) 125 (26): 4078–4084.

https://doi.org/10.1182/blood-2015-03-633958

Published: 2015

Includes: Supplemental data

Journal Articles

Hepatocyte tissue factor activates the coagulation cascade in mice

Bradley P. Sullivan, Anna K. Kopec, Nikita Joshi, Holly Cline, Juliette A. Brown, Stephanie C. Bishop, Karen M. Kassel, Cheryl Rockwell, Nigel Mackman, James P. Luyendyk

Blood (2013) 121 (10): 1868–1874.

https://doi.org/10.1182/blood-2012-09-455436

Published: 2013

Includes: Supplemental data

Journal Articles

Insulin Activation of PI3K Reduces Inflammation in a Mouse Model of Endotoxemia.

Nigel Mackman, PhD, Gernot Schabbauer, PhD, Michael Tencati, BSc, Todd Holscher, BSc, James P. Luyendyk, PhD

Blood (2005) 106 (11): 3078.

https://doi.org/10.1182/blood.V106.11.3078.3078

Published: 2005

NARROW

Reciprocal stabilization of coagulation factor XIII-A and -B subunits is a determinant of plasma FXIII concentration

Hypofibrinogenemia with preserved hemostasis and protection from thrombosis in mice with an Fga truncation mutation

Suppression of fibrin(ogen)-driven pathologies in disease models through controlled knockdown by lipid nanoparticle delivery of siRNA

Manipulation of Fatty Acid Metabolism Impairs Megakaryocyte Differentiation and Platelet Production

Plasmin-mediated cleavage of high-molecular-weight kininogen contributes to acetaminophen-induced acute liver failure

Factor XIII cross-links fibrin(ogen) independent of fibrin polymerization in experimental acute liver injury

A high-fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice

Intrahepatic fibrin(ogen) deposition drives liver regeneration after partial hepatectomy in mice and humans

The multifaceted role of fibrinogen in tissue injury and inflammation

Inflammation and Tissue Damage Mediated By PAR-1 Expression Is Cell Type-Specific and Varies Depending on the Inflammatory Challenge

Fibrin deposition following bile duct injury limits fibrosis through an α M β 2 -dependent mechanism

Tumor Cell Thrombin/PAR-1 Signaling Drives Pancreatic Ductal Adenocarcinoma Growth and Dissemination

Platelets and protease-activated receptor-4 contribute to acetaminophen-induced liver injury in mice

A balance between TFPI and thrombin-mediated platelet activation is required for murine embryonic development

Hepatocyte tissue factor activates the coagulation cascade in mice

Insulin Activation of PI3K Reduces Inflammation in a Mouse Model of Endotoxemia.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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