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Journal Articles

PC-002 (Sepantronium Bromide) Enhances the Antitumor Efficacy of Anti-CD20 Antibody By CD20 Upregulation

Vernon Jiang, Xiang LI, Na He, Yan Lv, Haiyue Wang, Ming Zhang, Heiyan Zhai, Zhen Yang, Yi Yang, Dagang Guo, Zhixiang Cao, Yiyou Chen
Journal: Blood
Blood (2024) 144 (Supplement 1): 5822.
https://doi.org/10.1182/blood-2024-209648
Published: 2024
Journal Articles

Sirolimus Combined Dexamethasone As the First-Line Therapy for Newly Diagnosed Adult Primary Immune Thrombocytopenia: A Multicenter, Open-Label, Prospective, Randomized Controlled Clinical Trial

Yimei Feng, Hanqing Zeng, Yi Liao, Yi Yang, Wenzheng Yu, Changyong Yuan, Guojun Li, Zhanshu Liu, Huae Shu, Guoxiang Zhang, Yaqing Feng, Chunfang Peng, Xiaoli Chen, Jia Liu, Han Yao, Ming Hou, Xi Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 1187.
https://doi.org/10.1182/blood-2024-207041
Published: 2024
Journal Articles

LILRB4 Synthetic T-Cell Receptor and Antigen Receptor-T (STAR-T) for Refractory/Relapsed Acute Myeloid Leukemia: First-in-Human Phase I Clinical Trial

Xiangyu Zhao, Meng Lv, Yu Wang, Yi-Yang Ding, Zhixiao Zhou, Jiasheng Wang, HongLi Zheng, Xueqiang Zhao, Xin Lin, Xiao Jun Huang
Journal: Blood
Blood (2024) 144 (Supplement 1): 4831.
https://doi.org/10.1182/blood-2024-207297
Published: 2024
Journal Articles

Association between JAK2 V617F-Clonal Hematopoiesis of Indeterminate Potential and Microthromboembolism-Related Diseases

Chih-Cheng Chen, Ying-Hsuan Wang, Cih-En Huang, Yi-Yang Chen
Journal: Blood
Blood (2024) 144 (Supplement 1): 5643.
https://doi.org/10.1182/blood-2024-202889
Published: 2024
Journal Articles

Profiling the E3 Ubiquitin Ligase Landscape in Normal and Sickle Red Blood Cells

Augustina Frimpong, Francisco Garcia, Chien-Hsiang Hsu, Michael Jones, Ning Guo, Hongjing Xia, Kevin Xie, Pamela Ting, Yi Yang
Journal: Blood
Blood (2022) 140 (Supplement 1): 11096.
https://doi.org/10.1182/blood-2022-163265
Published: 2022
Journal Articles

Thrombocytopenia in a Mouse Model of Pancreatic Cancer

Michelle M. Luo, Yaqiu Sang, Maria N. Barrachina, Andrew P. Stone, Keely G. Davey, Yi Yang, Lori A. Holle, Tomohiro Kawano, Nigel Mackman, Matthew J. Flick, Kellie R. Machlus, Alisa S. Wolberg
Journal: Blood
Blood (2022) 140 (Supplement 1): 8384.
https://doi.org/10.1182/blood-2022-169771
Published: 2022
Journal Articles

Pancreatic Ductal Adenocarcinoma Causes Bleeding Phenotype in Mice Associated with Loss of Procoagulant Activity and Increased Thrombomodulin Sensitivity

Michelle M. Luo, Keely G. Davey, Yohei Hisada, Yi Yang, Lori A. Holle, Ananya Dutta, Brian C. Cooley, Nigel Mackman, Matthew J. Flick, Alisa S. Wolberg
Journal: Blood
Blood (2022) 140 (Supplement 1): 11278.
https://doi.org/10.1182/blood-2022-169582
Published: 2022
Journal Articles

CRISPR/Cas9 Genome-Edited Autologous Hematopoietic Stem Cell Transplantation Therapies for Sickle Cell Disease

Yi Liu, Vionnie W. Yu, Qi Zhang, Madhura Panditrao, Yi Yang, Alberto Del Rio-Espinola, Daher Ibrahim Aibo, Azeddine Elhajouji, Konrad Mueller, Karin Abitorabi, Daniel O'Connell, Bo Han, Nishit Patel, Carsten Russ, Craig Mickanin, Timothy K. MacLachlan, Susan C. Stevenson
Journal: Blood
Blood (2022) 140 (Supplement 1): 12982–12983.
https://doi.org/10.1182/blood-2022-159892
Published: 2022
Journal Articles

Identification of functional cooperative mutations of GNAO1 in human acute lymphoblastic leukemia

Lili Song, Bo Yu, Yi Yang, Jianwei Liang, Yingwen Zhang, Lixia Ding, Tianyi Wang, Xinyu Wan, Xiaomin Yang, Jingyan Tang, Shengyue Wang, Benshang Li, Yanxin Li, Haizhong Feng
Journal: Blood
Blood (2021) 137 (9): 1181–1191.
https://doi.org/10.1182/blood.2020005622
Published: 2021
Includes: Supplemental data
Journal Articles

Therapeutic Effect of a Traditional Chinese Medicine Compound Mixture Compound Kushen Injection in Treating Multiple Myeloma

Hongqiang Jiang, PhD, Honglei Tu, Yanxia Jin, PhD, Xianjin Wu, Ziyi Luo, Yanling Chen, Dongdong Zhang, PhD, Balu Wu, Yongchang Wei, Yi Yang, Fuling Zhou, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 31–32.
https://doi.org/10.1182/blood-2020-141929
Published: 2020
Journal Articles

MDH1-mediated malate-aspartate NADH shuttle maintains the activity levels of fetal liver hematopoietic stem cells

Hao Gu, Chiqi Chen, Xiaoxin Hao, Ni Su, Dan Huang, Yejun Zou, Shu-Hai Lin, Xianjun Chen, Denghao Zheng, Ligen Liu, Zhuo Yu, Li Xie, Yaping Zhang, Xiaoxiao He, Xiaoyun Lai, Xiaocui Zhang, Guo-Qiang Chen, Yuzheng Zhao, Yi Yang, Joseph Loscalzo, Junke Zheng
Journal: Blood
Blood (2020) 136 (5): 553–571.
https://doi.org/10.1182/blood.2019003940
Published: 2020
Includes: Multimedia, Supplemental data
Journal Articles

Durable Responses with Pembrolizumab in Relapsed/Refractory Mycosis Fungoides and Sézary Syndrome: Final Results from a Phase 2 Multicenter Study

Michael S Khodadoust, MD PhD, Alain Rook, MD, Pierluigi Porcu, MD, Francine M. Foss, MD, Alison J. Moskowitz, MD, Andrei R. Shustov, MD, Satish Shanbhag, MD, Lubomir Sokol, MD PhD, Steven P Fling, PhD, Shufeng Li, MS, Asa Davis, PhD, Sophia Fong, BS, Jinah Kim, MD PhD, Yi Yang, Jennifer H Yearley, PhD DVM, Priyanka B Subrahmanyam, PhD, Holden T. Maecker, PhD, Yelena Budovskaya, PhD, Biswajit Das, PhD, Rajesh Patidar, PhD, Vivekananda Datta, MD PhD, Chris Karlovich, PhD, Steven M. Horwitz, MD, Elad Sharon, MD MPH, Holbrook Kohrt, MD PhD, Martin A Cheever, MD, Youn H. Kim, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2896.
https://doi.org/10.1182/blood-2018-99-117244
Published: 2018
Journal Articles

CRISPR/Cas9 Gene-Edited Hematopoietic Stem Cell Therapy for Sickle Cell Disease

Vionnie W. C. Yu, PhD, Yi Liu, PhD, Matthew Curran, Pu Zhang, MD, Jennifer Snead, PhD, Christian Schmedt, Yi Yang, PhD, Victor Guosheng Lin, William R Tschantz, PhD, Lisa Quinn, Carsten Russ, Scott Clarkson, Amy Janiak, Morag Stewart, PhD, Yanick Mulumba, Reynald Lescarbeau, Brad Murray, Jessica Seitzer, Walter Strapps, Hon-Ren Huang, Kevin Sloan, Craig S Mickanin, BS, Lloyd Klickstein, MD, Susan Stevenson
Journal: Blood
Blood (2017) 130 (Supplement 1): 535.
https://doi.org/10.1182/blood.V130.Suppl_1.535.535
Published: 2017
Journal Articles

Pembrolizumab for Treatment of Relapsed/Refractory Mycosis Fungoides and Sezary Syndrome: Clinical Efficacy in a Citn Multicenter Phase 2 Study

Michael Khodadoust, MD PhD, Alain H. Rook, MD, Pierluigi Porcu, MD, Francine M. Foss, MD, Alison J. Moskowitz, MD, Andrei R Shustov, MD, Satish Shanbhag, MBBS, MPH, Lubomir Sokol, MD PhD, Richard Shine, PharmD, Steven P Fling, PhD, Shufeng Li, MS, Ziba Rabhar, Jinah Kim, MD PhD, Yi Yang, Jennifer Yearley, DVM, PhD, Elliot Keith Chartash, MD, Steven M. Townson, PhD, Priyanka B Subrahmanyam, PhD, Holden Maecker, PhD, Ash A. Alizadeh, MD PhD, Julia Dai, MD, Steven M Horwitz, MD, Elad Sharon, MD MPH, Holbrook Kohrt, MD, Martin A Cheever, MD, Youn Kim, MD
Journal: Blood
Blood (2016) 128 (22): 181.
https://doi.org/10.1182/blood.V128.22.181.181
Published: 2016
Journal Articles

Aberrant Let7a/HMGA2 Signaling Axis with Unique Clinical Phenotype in JAK2 -Mutated Myeloproliferative Neoplasms

Chia-Chen Hsu, PhD, Chih-Cheng Chen, MD PhD, Jyh-Pyng Gau, MD PhD, Cih-En Huang, MD, Jie-Yu You, MD PhD, Jrhau Lung, PhD, YI-Yang Chen, Hsing-Ying Ho, MS, Chian-Pei Li, MS, Chang-Hsien Lu, MD, Kuan-Der Lee, MD PhD
Journal: Blood
Blood (2016) 128 (22): 5492.
https://doi.org/10.1182/blood.V128.22.5492.5492
Published: 2016
Journal Articles

Tumor Cell Thrombin/PAR-1 Signaling Drives Pancreatic Ductal Adenocarcinoma Growth and Dissemination

Matthew J. Flick, PhD, Cheryl Rewerts, M.S., Carolina Cruz, Joseph S. Palumbo, MD, James P. Luyendyk, PhD, Yi Yang, Stephen F. Konieczny, PhD
Journal: Blood
Blood (2015) 126 (23): 1070.
https://doi.org/10.1182/blood.V126.23.1070.1070
Published: 2015
Journal Articles

Favorable Clinical Outcome and Unique Characteristics in Association with Twist1 overexpression in De Novo Acute Myeloid Leukemia

Cih-En Huang, MD, Chih-Cheng Chen, MDPhD, Jyh-Pyng Gau, MD, Jie-Yu You, MD, Yi-Yang Chen, MD, Hui-Ju Chou, Jrhau Lung, Muh-Hwa Yang, MD
Journal: Blood
Blood (2014) 124 (21): 5263.
https://doi.org/10.1182/blood.V124.21.5263.5263
Published: 2014
Journal Articles

Chemical Genomics Reveals JAK STAT Activation As a Mechanism of Resistance to HDAC Inhibitors in B Cell Lymphomas

Matthew S. McKinney, MD, Anne W Beaven, MD, Andrea Moffitt, Jason Landon Smith, MD, Eric Lock, PhD, Dereje Jima, Jane Healy, MD PhD, Guojie Li, Adrienne Greenough, PhD, Cassandra L Love, MS, Xiao Yi Yang, MD, David Dunson, PhD, Herbert Kim Lyerly, MD, Leon Bernal-Mizrachi, MD, Randy D. Gascoyne, MD, Sandeep S. Dave, MD
Journal: Blood
Blood (2014) 124 (21): 271.
https://doi.org/10.1182/blood.V124.21.271.271
Published: 2014
Journal Articles

A Common Deletion Polymorphism in the BIM Gene Contributes to Intrinsic Imatinib Resistance in Chronic Myelogenous Leukemia

Axel M Hillmer, PhD, King-Pan Ng, PhD, Charles Chuah, MBChB, FRCPE, MD, Wen Chun Juan, B.Sc, Tun-Kiat Ko, PhD, Audrey S.M. Teo, M.Sc, Pramila N Ariyaratne, M.Sc, Naoto Takahashi, MD, PhD, Kenichi Sawada, MD, PhD, Yao Fei, M.Sc, Wah Heng Lee, PhD, Weijie Huang, B.Sc, John C Allen, Jr., PhD, Xing Yi Woo, PhD, Niranjan Nagarajan, PhD, Vikrant Kumar, PhD, Anbupalam Thalamuthu, PhD, Wan Ting Poh, B.S, Ai Leen Ang, MBBS, MMed, (Internal, Medicine), Hae Tha Mya, M.B.B.S, Gee Fung How, PhD, Li Yi Yang, B.Sc, Liang Piu Koh, M.B.B.S, Veera S Nadarajan, M.B.B.S, Wee-Joo Chng, M.B.Ch.B, Hein Than, M.B.B.S, Lay Cheng Lim, MD, Yeow-Tee Goh, MBBS, MMed, Markus M Nöthen, M.D, Tien Y Wong, M.D, PhD, Atif Shahab, PhD, Xiaoan Ruan, PhD, Valère Cacheux-Rataboul, PhD, Wing-Kin Sung, PhD, Yijun Ruan, PhD, S. Tiong Ong, M.A., M.B.B.Ch., M.R.C.P., (UK)
Journal: Blood
Blood (2011) 118 (21): 1666.
https://doi.org/10.1182/blood.V118.21.1666.1666
Published: 2011
Journal Articles

Bone Marrow Hypoplasia Induced by Conditional Knockout of the RNase III Domain of Dicer-1

Tai-Chung Huang, M.D., Yi Yang, M.D., Ph.D., Cory Brayton, D.V.M., Wen-Chien Chou, MD, PhD, Akhilesh Pandey, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2226.
https://doi.org/10.1182/blood.V116.21.2226.2226
Published: 2010